Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury

Journal of Biological Chemistry

Volumn 286, Issue 12, 2011, Pages 10660-10670

  Finigan, James H ^a,d   Faress, Jihane A ^a   Wilkinson, Emily ^a   Mishra, Rangnath S ^a   Nethery, David E ^a   Wyler, David ^a   Shatat, Mohammad ^a   Ware, Lorraine B ^b   Matthay, Michael A ^c   Mason, Robert ^d   Silver, Richard F ^a   Kern, Jeffrey A ^d  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d DEPARTMENT OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LUNG INJURY; AIRWAY EPITHELIAL CELLS; EPITHELIAL BARRIER; EPITHELIAL PERMEABILITY; HUMAN EPIDERMAL GROWTH FACTOR; HUMAN EPITHELIAL CELLS; IN-VIVO; INTERLEUKIN-1; LUNG INJURY; MECHANISTIC STUDIES; METALLO-PROTEASE; MURINE MODEL; NEUREGULIN; PATHOPHYSIOLOGY; PULMONARY EDEMA; TYROSINE KINASE;

AMINO ACIDS; CELLS; MONOLAYERS; SIGNALING;

BIOLOGICAL ORGANS;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; INTERLEUKIN 1BETA; NEU DIFFERENTIATION FACTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ACUTE LUNG INJURY; ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

ACUTE LUNG INJURY; ADAM PROTEINS; ANIMALS; BLOOD-AIR BARRIER; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-1BETA; MICE; NEUREGULIN-1; PERMEABILITY; RECEPTOR, ERBB-2; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

MURINAE;

EID: 79953214031     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.208041     Document Type: Article

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