Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?

Critical Care

Volumn 15, Issue 2, 2011, Pages

  Curley, Gerard ^a   Hayes, Mairead ^a   Laffey, John G ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ADAPTIVE IMMUNITY; ANTIBIOTIC THERAPY; B LYMPHOCYTE; BACTERIAL INFECTION; CELLULAR IMMUNITY; DISEASE SEVERITY; EFFECTOR CELL; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HYPERCAPNIA; IMMUNOMODULATION; INNATE IMMUNITY; LUNG INFECTION; LYMPHOKINE ACTIVATED KILLER CELL; MACROPHAGE; METABOLIC ACIDOSIS; MONOCYTE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY ACIDOSIS; RESPIRATORY DISTRESS; REVIEW; SEPSIS; T LYMPHOCYTE; ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; BACTEREMIA; IMMUNOLOGY; METHODOLOGY;

ACIDOSIS, RESPIRATORY; ADAPTIVE IMMUNITY; BACTEREMIA; HUMANS; HYPERCAPNIA; IMMUNITY, INNATE; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS;

EID: 79953017464     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9994     Document Type: Review

References (45)

1. The ARDS Network Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000, 342:1301-1308. 10.1056/NEJM200005043421801, 10793162, The ARDS Network.
2. Hickling KG, Walsh J, Henderson S, Jackson R. Low mortality rate in adult respiratory distress syndrome using low-volume, pressure-limited ventilation with permissive hypercapnia: a prospective study. Crit Care Med 1994, 22:1568-1578. 10.1097/00003246-199422100-00011, 7924367.
3. Kregenow DA, Rubenfeld GD, Hudson LD, Swenson ER. Hypercapnic acidosis and mortality in acute lung injury. Crit Care Med 2006, 34:1-7. 10.1097/01.CCM.0000194533.75481.03, 16374149.
4. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000, 342:1334-1349. 10.1056/NEJM200005043421806, 10793167.
5. Barton GM. A calculated response: control of inflammation by the innate immune system. J Clin Invest 2008, 118:413-420. 10.1172/JCI34431, 2214713, 18246191.
6. Laffey JG, Kavanagh BP. Carbon dioxide and the critically ill-too little of a good thing?. Lancet 1999, 354:1283-1286. 10.1016/S0140-6736(99)02388-0, 10520649.
7. Laffey JG, O'Croinin D, McLoughlin P, Kavanagh BP. Permissive hypercapnia- role in protective lung ventilatory strategies. Intensive Care Med 2004, 30:347-356. 10.1007/s00134-003-2051-1, 14722644.
8. Shibata K, Cregg N, Engelberts D, Takeuchi A, Fedorko L, Kavanagh BP. Hypercapnic acidosis may attenuate acute lung injury by inhibition of endogenous xanthine oxidase. Am J Respir Crit Care Med 1998, 158:1578-1584.
9. Laffey JG, Jankov RP, Engelberts D, et al. Effects of therapeutic hypercapnia on mesenteric ischemia-reperfusion injury. Am J Respir Crit Care Med 2003, 168:1383-1390. 10.1164/rccm.2108078, 14644926.
10. Laffey JG, Tanaka M, Engelberts D, et al. Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion. Am J Respir Crit Care Med 2000, 162:2287-2294.
11. Laffey JG, Honan D, Hopkins N, Hyvelin JM, Boylan JF, McLoughlin P. Hypercapnic acidosis attenuates endotoxin-induced acute lung injury. Am J Respir Crit Care Med 2004, 169:46-56. 10.1164/rccm.200205-394OC, 12958048.
12. Sinclair SE, Kregenow DA, Lamm WJ, Starr IR, Chi EY, Hlastala MP. Hypercapnic acidosis is protective in an in vivo model of ventilator-induced lung injury. Am J Respir Crit Care Med 2002, 166:403-408. 10.1164/rccm.200112-117OC, 12153979.
13. Hudson LD, Milberg JA, Anardi D, Maunder RJ. Clinical risks for development of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1995, 51:293-301.
14. Vincent JL, Bihari DJ, Suter PM, et al. The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 1995, 274:639-644. 10.1001/jama.274.8.639, 7637145.
15. Zhang Q, Raoof M, Chen Y, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010, 464:104-107. 10.1038/nature08780, 2843437, 20203610.
16. Takeshita K, Suzuki Y, Nishio K, et al. Hypercapnic acidosis attenuates endotoxin-induced nuclear factor-kappa B activation. Am J Respir Cell Mol Biol 2003, 29:124-132. 10.1165/rcmb.2002-0126OC, 12600832.
17. Cummins EP, Oliver KM, Lenihan CR, et al. NF-kB links CO2 sensing to innate immunity and inflammation in mammalian cells. J Immunol 2010, 185:4439-44. 10.4049/jimmunol.1000701, 20817876.
18. O'Toole D, Hassett P, Contreras M, et al. Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappaB dependent mechanism. Thorax 2009, 64:976-982. 10.1136/thx.2008.110304, 19617214.
19. Wang N, Gates KL, Trejo H, et al. Elevated CO2 selectively inhibits interleukin-6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage. Faseb J 2010, 24:2178-2190. 10.1096/fj.09-136895, 20181940.
20. Coakley RJ, Taggart C, Greene C, McElvaney NG, O'Neill SJ. Ambient pCO2 modulates intracellular pH, intracellular oxidant generation, and interleukin-8 secretion in human neutrophils. J Leukoc Biol 2002, 71:603-610.
21. West MA, Baker J, Bellingham J. Kinetics of decreased LPS-stimulated cytokine release by macrophages exposed to CO2. J Surg Res 1996, 63:269-274. 10.1006/jsre.1996.0259, 8661209.
22. Gupta A, Watson DI. Effect of laparoscopy on immune function. Br J Surg 2001, 88:1296-1306. 10.1046/j.0007-1323.2001.01860.x, 11578282.
23. O'Croinin DF, Nichol AD, Hopkins N, et al. Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury. Crit Care Med 2008, 36:2128-2135. 10.1097/CCM.0b013e31817d1b59, 18552698.
24. Nichol AD, O'Cronin DF, Howell K, et al. Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis. Crit Care Med 2009, 37:2953-2961. 10.1097/CCM.0b013e3181b028ce, 19773647.
25. Swallow CJ, Grinstein S, Sudsbury RA, Rotstein OD. Relative roles of Na+/H+ exchange and vacuolar-type H+ ATPases in regulating cytoplasmic pH and function in murine peritoneal macrophages. J Cell Physiol 1993, 157:453-460. 10.1002/jcp.1041570304, 8253856.
26. Nichol AD, O'Cronin DF, Naughton F, Hopkins N, Boylan J, McLoughlin P. Hypercapnic acidosis reduces oxidative reactions in endotoxin-induced lung injury. Anesthesiology 2010, 113:116-125. 10.1097/ALN.0b013e3181dfd2fe, 20526182.
27. Coakley RJ, Taggart C, McElvaney NG, O'Neill SJ. Cytosolic pH and the inflammatory microenvironment modulate cell death in human neutrophils after phagocytosis. Blood 2002, 100:3383-3391. 10.1182/blood.V100.9.3383, 12384441.
28. Severin T, Muller B, Giese G, et al. pH-dependent LAK cell cytotoxicity. Tumour Biol 1994, 15:304-310. 10.1159/000217905, 7991991.
29. Redegeld F, Filippini A, Sitkovsky M. Comparative studies of the cytotoxic T lymphocyte-mediated cytotoxicity and of extracellular ATP-induced cell lysis. Different requirements in extracellular Mg2+ and pH. J Immunol 1991, 147:3638-3645.
30. Vermeulen M, Giordano M, Trevani AS, et al. Acidosis improves uptake of antigens and MHC class I-restricted presentation by dendritic cells. J Immunol 2004, 172:3196-3204.
31. Metzelder M, Kuebler JF, Shimotakahara A, Chang DH, Vieten G, Ure BL. CO2 pneumoperitoneum increases survival in mice with polymicrobial peritonitis. Eur J Pediatr Surg 2008, 18:171-175. 10.1055/s-2008-1038365, 18493892.
32. Dixon NM, Kell DB. The inhibition by CO2 of the growth and metabolism of micro-organisms. J Appl Bacteriol 1989, 67:109-136.
33. Mori H, Kobayashi T, Shimizu S. Effect of carbon dioxide on growth of microorganisms in fed-batch cultures. J Ferment Technol 1983, 61:211-213.
34. Pugin J, Dunn-Siegrist I, Dufour J, Tissieres P, Charles PE, Comte R. Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth. Am J Respir Cell Mol Biol 2008, 38:362-370. 10.1165/rcmb.2007-0114OC, 17921360.
35. Azoulay E, Darmon M, Delclaux C, et al. Deterioration of previous acute lung injury during neutropenia recovery. Crit Care Med 2002, 30:781-786. 10.1097/00003246-200204000-00010, 11940745.
36. Alves-Filho JC, de Freitas A, Spiller F, Souto FO, Cunha FQ. The role of neutrophils in severe sepsis. Shock 2008, 30(Suppl 1):3-9. 10.1097/SHK.0b013e3181818466, 18704017.
37. Doerr CH, Gajic O, Berrios JC, et al. Hypercapnic acidosis impairs plasma membrane wound resealing in ventilator-injured lungs. Am J Respir Crit Care Med 2005, 171:1371-1377. 10.1164/rccm.200309-1223OC, 2718480, 15695495.
38. Ni Chonghaile M, Higgins BD, Costello JF, Laffey JG. Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism. Crit Care Med 2008, 36:3135-3144. 10.1097/CCM.0b013e31818f0d13, 18936707.
39. O'Croinin DF, Hopkins NO, Moore MM, Boylan JF, McLoughlin P, Laffey JG. Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury. Crit Care Med 2005, 33:2606-2612. 10.1097/01.CCM.0000186761.41090.C6, 16276187.
40. Chonghaile MN, Higgins BD, Costello J, Laffey JG. Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumonia. Anesthesiology 2008, 109:837-848. 10.1097/ALN.0b013e3181895fb7, 18946296.
41. Helenius IT, Krupinski T, Turnbull DW, et al. Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:18710-18715. 10.1073/pnas.0905925106, 2773965, 19846771.
42. Costello J, Higgins B, Contreras M, et al. Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis. Crit Care Med 2009, 37:2412-2420. 10.1097/CCM.0b013e3181a385d3, 19531945.
43. Wang Z, Su F, Bruhn A, Yang X, Vincent JL. Acute hypercapnia improves indices of tissue oxygenation more than dobutamine in septic shock. Am J Respir Crit Care Med 2008, 177:178-183. 10.1164/rccm.200706-906OC, 17947612.
44. Fuentes JM, Hanly EJ, Aurora AR, et al. CO2 abdominal insufflation pretreatment increases survival after a lipopolysaccharide-contaminated laparotomy. J Gastrointest Surg 2006, 10:32-38. 10.1016/j.gassur.2005.07.031, 16368488.
45. Higgins BD, Costello J, Contreras M, Hassett P, D OT, Laffey JG. Differential Effects of Buffered Hypercapnia versus Hypercapnic Acidosis on Shock and Lung Injury Induced by Systemic Sepsis. Anesthesiology 2009, 111:1317-1326. 10.1097/ALN.0b013e3181ba3c11, 19934878.