Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway

GLIA

Volumn 63, Issue 1, 2015, Pages 78-90

  Ott, Martina ^a   Litzenburger, Ulrike M ^a   Rauschenbach, Katharina J ^a   Bunse, Lukas ^a   Ochs, Katharina ^a   Sahm, Felix ^a   Pusch, Stefan ^a   Opitz, Christiane A ^a   Blaes, Jonas ^a   von Deimling, Andreas ^a   Wick, Wolfgang ^a   Platten, Michael ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Glioma; Glucocorticoid; Kynurenine; Tryptophan; Tumor immune escape

Indexed keywords

DEXAMETHASONE; FKBP52 PROTEIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOPHILIN; KYNURENINE; SMALL INTERFERING RNA; STEROID; TACROLIMUS; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG; FK 506 BINDING PROTEIN; TACROLIMUS BINDING PROTEIN 4;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CANCER IMMUNOTHERAPY; CATABOLISM; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; FEMALE; FLUORESCENCE; GENE EXPRESSION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AGING; ANIMALS; CELL LINE, TUMOR; DEXAMETHASONE; GLIOBLASTOMA; HUMANS; MICE; SIGNAL TRANSDUCTION; TACROLIMUS; TACROLIMUS BINDING PROTEINS; TRYPTOPHAN; TRYPTOPHAN OXYGENASE;

EID: 84911989626     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22734     Document Type: Article

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