Alteration of Scn3a expression is mediated via CpG methylation and MBD2 in mouse hippocampus during postnatal development and seizure condition

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1849, Issue 1, 2015, Pages 1-9

  Li, Hai Jun ^a,b   Wan, Rui Ping ^a   Tang, Ling Jia ^a   Liu, Shu Jing ^a   Zhao, Qi Hua ^a   Gao, Mei Mei ^a   Yi, Yong Hong ^a   Liao, Wei Ping ^a   Sun, Xiao Fang ^b   Long, Yue Sheng ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b Key Laboratory for Major Obstetric Diseases of Guangdong Province   (China)

Author keywords

CpG methylation; MBD2; Promoter; Scn3a; Seizure

Indexed keywords

MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; SODIUM CHANNEL NAV1.3; DNA BINDING PROTEIN; MBD2 PROTEIN, MOUSE; SCN3A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; GENE EXPRESSION; HIPPOCAMPUS; MALE; METHYLATION; MOUSE; MUTATION; NONHUMAN; POSTNATAL DEVELOPMENT; PROMOTER REGION; REPORTER GENE; SEIZURE; UPREGULATION; ANIMAL; BIOSYNTHESIS; DNA METHYLATION; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; PATHOLOGY;

ANIMALS; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HUMANS; MICE; NAV1.3 VOLTAGE-GATED SODIUM CHANNEL; RNA, MESSENGER; SEIZURES; TRANSCRIPTION, GENETIC;

EID: 84911919894     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2014.11.004     Document Type: Article

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