DJ-1 plays an important role in caffeic acid-mediated protection of the gastrointestinal mucosa against ketoprofen-induced oxidative damage

Journal of Nutritional Biochemistry

Volumn 25, Issue 10, 2014, Pages 1045-1057

  Cheng, Yu Ting ^a   Ho, Cheng Ying ^a   Jhang, Jhih Jia ^a   Lu, Chi Cheng ^a   Yen, Gow Chin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Caffeic acid; DJ 1; Gastrointestinal ulcer; HO 1; Ketoprofen; Nrf2; NSAIDs

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; APIGENIN; BETA CAROTENE; CAFFEIC ACID; CYANIDIN; DJ 1 PROTEIN; FERULIC ACID; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; KETOPROFEN; LACTATE DEHYDROGENASE; LYCOPENE; MALONALDEHYDE; MALVIDIN CHLORIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; PROTOPORPHYRIN ZINC; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; THEAFLAVIN; THIOL GROUP; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; CYCLOOXYGENASE 2; MICROTUBULE ASSOCIATED PROTEIN; NFE2L2 PROTEIN, HUMAN; NFE2L2 PROTEIN, RAT; NONSTEROID ANTIINFLAMMATORY AGENT; ONCOPROTEIN; PARK7 PROTEIN, HUMAN; PTGS2 PROTEIN, RAT; REACTIVE OXYGEN METABOLITE; SIGNAL PEPTIDE; SP22 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL MUCOSA PROTECTION; GASTROINTESTINAL TOXICITY; GENE EXPRESSION; GENE SILENCING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTECTION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; GASTROINTESTINAL TRACT; GENE TRANSLOCATION; GENETICS; INFLAMMATION; METABOLISM; MUCOSA; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; CAFFEIC ACIDS; CELL LINE; CYCLOOXYGENASE 2; EPITHELIAL CELLS; GASTROINTESTINAL TRACT; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE-1; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KETOPROFEN; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MUCOUS MEMBRANE; NF-E2-RELATED FACTOR 2; ONCOGENE PROTEINS; OXIDATIVE STRESS; PHYTOCHEMICALS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRANSLOCATION, GENETIC;

EID: 84911882085     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2014.05.007     Document Type: Article

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