-
1
-
-
1242286146
-
Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions
-
Tomisato W, Tsutsumi S, Hoshino T, et al. Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions. Biochem Pharmacol 2004 67 : 575 85.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 575-585
-
-
Tomisato, W.1
Tsutsumi, S.2
Hoshino, T.3
-
3
-
-
34548451974
-
Reactive oxygen species in mitochondria-mediated cell death
-
Orrenius S. Reactive oxygen species in mitochondria-mediated cell death. Drug Metab Rev 2007 39 : 443 55.
-
(2007)
Drug Metab Rev
, vol.39
, pp. 443-455
-
-
Orrenius, S.1
-
4
-
-
25644432016
-
Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells
-
Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci 2005 50 (Suppl 1) S76 83.
-
(2005)
Dig Dis Sci
, vol.50
, Issue.SUPPL. 1
-
-
Nagano, Y.1
Matsui, H.2
Muramatsu, M.3
-
5
-
-
3242706202
-
The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice
-
Darling RL, Romero JJ, Dial EJ, Akunda JK, Langenbach R, Lichtenberger LM. The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice. Gastroenterology 2004 127 : 94 104.
-
(2004)
Gastroenterology
, vol.127
, pp. 94-104
-
-
Darling, R.L.1
Romero, J.J.2
Dial, E.J.3
Akunda, J.K.4
Langenbach, R.5
Lichtenberger, L.M.6
-
6
-
-
33751226593
-
NSAID injury to the gastrointestinal tract: Evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable pores in membranes
-
Lichtenberger LM, Zhou Y, Dial EJ, Raphael RM. NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable pores in membranes. J Pharm Pharmacol 2006 58 : 1421 8.
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 1421-1428
-
-
Lichtenberger, L.M.1
Zhou, Y.2
Dial, E.J.3
Raphael, R.M.4
-
7
-
-
33746632611
-
Oral but not parenteral aspirin upregulates COX-2 expression in rat stomachs. A relationship between COX-2 expression and PG deficiency
-
Mashita Y, Taniguchi M, Yokota A, Tanaka A, Takeuchi K. Oral but not parenteral aspirin upregulates COX-2 expression in rat stomachs. a relationship between COX-2 expression and PG deficiency. Digestion 2006 73 : 124 32.
-
(2006)
Digestion
, vol.73
, pp. 124-132
-
-
Mashita, Y.1
Taniguchi, M.2
Yokota, A.3
Tanaka, A.4
Takeuchi, K.5
-
8
-
-
33846082831
-
Oxidative stress involvement and gene expression in indomethacin-induced gastropathy
-
Naito Y, Yoshikawa T. Oxidative stress involvement and gene expression in indomethacin-induced gastropathy. Redox Rep 2006 11 : 243 53.
-
(2006)
Redox Rep
, vol.11
, pp. 243-253
-
-
Naito, Y.1
Yoshikawa, T.2
-
9
-
-
33646484112
-
Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen
-
Chattopadhyay I, Bandyopadhyay U, Biswas K, Maity P, Banerjee RK. Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen. Free Radic Biol Med 2006 40 : 1397 408.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1397-1408
-
-
Chattopadhyay, I.1
Bandyopadhyay, U.2
Biswas, K.3
Maity, P.4
Banerjee, R.K.5
-
10
-
-
33751019656
-
Prostaglandin E2 receptor distribution and function in the gastrointestinal tract
-
Dey I, Lejeune M, Chadee K. Prostaglandin E2 receptor distribution and function in the gastrointestinal tract. Br J Pharmacol 2006 149 : 611 23.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 611-623
-
-
Dey, I.1
Lejeune, M.2
Chadee, K.3
-
11
-
-
0033851568
-
NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2
-
Wallace JL, McKnight W, Reuter BK, Vergnolle N. NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 2000 119 : 706 14.
-
(2000)
Gastroenterology
, vol.119
, pp. 706-714
-
-
Wallace, J.L.1
McKnight, W.2
Reuter, B.K.3
Vergnolle, N.4
-
12
-
-
0035067053
-
Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge
-
Gretzer B, Maricic N, Respondek M, Schuligoi R, Peskar BM. Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge. Br J Pharmacol 2001 132 : 1565 73.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1565-1573
-
-
Gretzer, B.1
Maricic, N.2
Respondek, M.3
Schuligoi, R.4
Peskar, B.M.5
-
13
-
-
0034747922
-
Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs
-
Tanaka A, Araki H, Komoike Y, Hase S, Takeuchi K. Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs. J Physiol Paris 2001 95 : 21 7.
-
(2001)
J Physiol Paris
, vol.95
, pp. 21-27
-
-
Tanaka, A.1
Araki, H.2
Komoike, Y.3
Hase, S.4
Takeuchi, K.5
-
14
-
-
0345866794
-
Interaction of cyclooxygenase isoenzymes, nitric oxide, and afferent neurons in gastric mucosal defense in rats
-
Ehrlich K, Sicking C, Respondek M, Peskar BM. Interaction of cyclooxygenase isoenzymes, nitric oxide, and afferent neurons in gastric mucosal defense in rats. J Pharmacol Exp Ther 2004 308 : 277 83.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 277-283
-
-
Ehrlich, K.1
Sicking, C.2
Respondek, M.3
Peskar, B.M.4
-
15
-
-
0036551298
-
Up-regulation of COX-2 by inhibition of COX-1 in the rat: A key to NSAID-induced gastric injury
-
Tanaka A, Araki H, Hase S, Komoike Y, Takeuchi K. Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury. Aliment Pharmacol Ther 2002 16 (Suppl 2) 90 101.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, Issue.SUPPL. 2
, pp. 90-101
-
-
Tanaka, A.1
Araki, H.2
Hase, S.3
Komoike, Y.4
Takeuchi, K.5
-
16
-
-
33645837239
-
Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice
-
Schmassmann A, Zoidl G, Peskar BM, et al. Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice. Am J Physiol Gastrointest Liver Physiol 2006 290 : G747 56.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Schmassmann, A.1
Zoidl, G.2
Peskar, B.M.3
-
17
-
-
0035176365
-
Up-regulation of cyclooxygenase-1 and -2 in human gastric ulcer
-
To KF, Chan FK, Cheng AS, Lee TL, Ng YP, Sung JJ. Up-regulation of cyclooxygenase-1 and -2 in human gastric ulcer. Aliment Pharmacol Ther 2001 15 : 25 34.
-
(2001)
Aliment Pharmacol Ther
, vol.15
, pp. 25-34
-
-
To, K.F.1
Chan, F.K.2
Cheng, A.S.3
Lee, T.L.4
Ng, Y.P.5
Sung, J.J.6
-
18
-
-
14844307023
-
Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa
-
Bhandari P, Bateman AC, Mehta RL, Patel P. Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa. Histopathology 2005 46 : 280 6.
-
(2005)
Histopathology
, vol.46
, pp. 280-286
-
-
Bhandari, P.1
Bateman, A.C.2
Mehta, R.L.3
Patel, P.4
-
20
-
-
33645811931
-
Effect of Celecoxib on the Healing of Complicated Gastric Ulcers: A Prospective, Double Rounded Randomised Trial
-
(Abstract).
-
Chan FK, Wong VW, Suen BY, et al. Effect of Celecoxib on the Healing of Complicated Gastric Ulcers: a Prospective, Double Rounded Randomised Trial (Abstract). Gasroenterology 2005 128 : A24.
-
(2005)
Gasroenterology
, vol.128
-
-
Chan, F.K.1
Wong, V.W.2
Suen, B.Y.3
-
21
-
-
61849111082
-
A randomized, placebo-controlled study of the effects of naproxen, aspirin, celecoxib or clopidogrel on gastroduodenal mucosal healing
-
Dikman A, Sanyal S, Von AC, et al. A randomized, placebo-controlled study of the effects of naproxen, aspirin, celecoxib or clopidogrel on gastroduodenal mucosal healing. Aliment Pharmacol Ther 2009 29 : 781 91.
-
(2009)
Aliment Pharmacol Ther
, vol.29
, pp. 781-791
-
-
Dikman, A.1
Sanyal, S.2
Von, A.C.3
-
22
-
-
12444344791
-
Functional mechanism underlying cyclooxygenase-2 expression in rat small intestine following administration of indomethacin: Relation to intestinal hypermotility
-
Tanaka A, Matsumoto M, Hayashi Y, Takeuchi K. Functional mechanism underlying cyclooxygenase-2 expression in rat small intestine following administration of indomethacin: relation to intestinal hypermotility. J Gastroenterol Hepatol 2005 20 : 38 45.
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 38-45
-
-
Tanaka, A.1
Matsumoto, M.2
Hayashi, Y.3
Takeuchi, K.4
-
23
-
-
0033638131
-
Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach
-
Barnett K, Bell CJ, McKnight W, Dicay M, Sharkey KA, Wallace JL. Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach. Am J Physiol Gastrointest Liver Physiol 2000 279 : G1292 7.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Barnett, K.1
Bell, C.J.2
McKnight, W.3
Dicay, M.4
Sharkey, K.A.5
Wallace, J.L.6
-
24
-
-
0036149015
-
NSAID gastric ulceration: Predictive value of gastric pH, mucosal density of polymorphonuclear leukocytes, or levels of IL-8 or nitrite
-
Shiotani A, Yamaoka Y, El-Zimaity HM, Saeed MA, Qureshi WA, Graham DY. NSAID gastric ulceration: predictive value of gastric pH, mucosal density of polymorphonuclear leukocytes, or levels of IL-8 or nitrite. Dig Dis Sci 2002 47 : 38 43.
-
(2002)
Dig Dis Sci
, vol.47
, pp. 38-43
-
-
Shiotani, A.1
Yamaoka, Y.2
El-Zimaity, H.M.3
Saeed, M.A.4
Qureshi, W.A.5
Graham, D.Y.6
-
26
-
-
33751436594
-
Mucosal acid causes gastric mucosal microcirculatory disturbance in nonsteroidal anti-inflammatory drug-treated rats
-
Funatsu T, Chono K, Hirata T, Keto Y, Kimoto A, Sasamata M. Mucosal acid causes gastric mucosal microcirculatory disturbance in nonsteroidal anti-inflammatory drug-treated rats. Eur J Pharmacol 2007 554 : 53 9.
-
(2007)
Eur J Pharmacol
, vol.554
, pp. 53-59
-
-
Funatsu, T.1
Chono, K.2
Hirata, T.3
Keto, Y.4
Kimoto, A.5
Sasamata, M.6
-
27
-
-
33744459216
-
Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection
-
Wallace JL. Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection. Inflamm Allergy Drug Targets 2006 5 : 133 7.
-
(2006)
Inflamm Allergy Drug Targets
, vol.5
, pp. 133-137
-
-
Wallace, J.L.1
-
28
-
-
23044505095
-
Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells
-
Nascimento-Silva V, Arruda MA, Barja-Fidalgo C, Villela CG, Fierro IM. Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells. Am J Physiol Cell Physiol 2005 289 : C557 63.
-
(2005)
Am J Physiol Cell Physiol
, vol.289
-
-
Nascimento-Silva, V.1
Arruda, M.A.2
Barja-Fidalgo, C.3
Villela, C.G.4
Fierro, I.M.5
-
29
-
-
6344259980
-
Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial
-
Chiang N, Bermudez EA, Ridker PM, Hurwitz S, Serhan CN. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. Proc Natl Acad Sci U S A 2004 101 : 15178 83.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15178-15183
-
-
Chiang, N.1
Bermudez, E.A.2
Ridker, P.M.3
Hurwitz, S.4
Serhan, C.N.5
-
30
-
-
0141479985
-
Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa
-
Fiorucci S, Santucci L, Wallace JL, et al. Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa. Proc Natl Acad Sci U S A 2003 100 : 10937 41.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10937-10941
-
-
Fiorucci, S.1
Santucci, L.2
Wallace, J.L.3
-
31
-
-
0036828285
-
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage
-
Fiorucci S, de LO Jr., Mencarelli A, et al. Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage. Gastroenterology 2002 123 : 1598 606.
-
(2002)
Gastroenterology
, vol.123
, pp. 1598-1606
-
-
Fiorucci, S.1
De Jr., L.O.2
Mencarelli, A.3
-
32
-
-
21244441174
-
Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense
-
Wallace JL, Devchand PR. Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense. Br J Pharmacol 2005 145 : 275 82.
-
(2005)
Br J Pharmacol
, vol.145
, pp. 275-282
-
-
Wallace, J.L.1
Devchand, P.R.2
-
33
-
-
3142749700
-
15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation
-
Paul-Clark MJ, Van CT, Moradi-Bidhendi N, Cooper D, Gilroy DW. 15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation. J Exp Med 2004 200 : 69 78.
-
(2004)
J Exp Med
, vol.200
, pp. 69-78
-
-
Paul-Clark, M.J.1
Van, C.T.2
Moradi-Bidhendi, N.3
Cooper, D.4
Gilroy, D.W.5
-
34
-
-
36549020979
-
Role of visceral afferent neurons in mucosal inflammation and defense
-
Holzer P. Role of visceral afferent neurons in mucosal inflammation and defense. Curr Opin Pharmacol 2007 7 : 563 9.
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 563-569
-
-
Holzer, P.1
-
35
-
-
37349026909
-
Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis
-
Ohno T, Hattori Y, Komine R, et al. Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. Gastroenterology 2008 134 : 215 25.
-
(2008)
Gastroenterology
, vol.134
, pp. 215-225
-
-
Ohno, T.1
Hattori, Y.2
Komine, R.3
-
36
-
-
33845600464
-
Contribution of sensory neurons to sex difference in the development of stress-induced gastric mucosal injury in mice
-
Shimozawa N, Okajima K, Harada N, et al. Contribution of sensory neurons to sex difference in the development of stress-induced gastric mucosal injury in mice. Gastroenterology 2006 131 : 1826 34.
-
(2006)
Gastroenterology
, vol.131
, pp. 1826-1834
-
-
Shimozawa, N.1
Okajima, K.2
Harada, N.3
-
37
-
-
33847019182
-
Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats
-
Shimozawa N, Okajima K, Harada N. Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. Am J Physiol Gastrointest Liver Physiol 2007 292 : G615 9.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
-
-
Shimozawa, N.1
Okajima, K.2
Harada, N.3
-
38
-
-
34247204039
-
Preventive effects of rebamipide on NSAID-induced gastric mucosal injury and reduction of gastric mucosal blood flow in healthy volunteers
-
Kim HK, Kim JI, Kim JK, et al. Preventive effects of rebamipide on NSAID-induced gastric mucosal injury and reduction of gastric mucosal blood flow in healthy volunteers. Dig Dis Sci 2007 52 : 1776 82.
-
(2007)
Dig Dis Sci
, vol.52
, pp. 1776-1782
-
-
Kim, H.K.1
Kim, J.I.2
Kim, J.K.3
-
39
-
-
4644231135
-
Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha
-
Watanabe T, Higuchi K, Hamaguchi M, et al. Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha. Am J Physiol Gastrointest Liver Physiol 2004 287 : G919 28.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Watanabe, T.1
Higuchi, K.2
Hamaguchi, M.3
-
40
-
-
2442686478
-
Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide synthase (iNOS) deficient mice
-
Souza MH, Lemos HP, Oliveira RB, Cunha FQ. Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide synthase (iNOS) deficient mice. Gut 2004 53 : 791 6.
-
(2004)
Gut
, vol.53
, pp. 791-796
-
-
Souza, M.H.1
Lemos, H.P.2
Oliveira, R.B.3
Cunha, F.Q.4
-
41
-
-
32244447306
-
Gastrointestinal inflammation: A central component of mucosal defense and repair
-
Martin GR, Wallace JL. Gastrointestinal inflammation: a central component of mucosal defense and repair. Exp Biol Med (Maywood.) 2006 231 : 130 7.
-
(2006)
Exp Biol Med (Maywood.)
, vol.231
, pp. 130-137
-
-
Martin, G.R.1
Wallace, J.L.2
-
42
-
-
34250313282
-
Up-regulation of TFF1 (pS2) expression by TNF-alpha in gastric epithelial cells
-
Koike T, Shimada T, Fujii Y, et al. Up-regulation of TFF1 (pS2) expression by TNF-alpha in gastric epithelial cells. J Gastroenterol Hepatol 2007 22 : 936 42.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 936-942
-
-
Koike, T.1
Shimada, T.2
Fujii, Y.3
-
43
-
-
0034087137
-
Growth factors in ulcer healing: Lessons from recent studies
-
Szabo S, Vincze A. Growth factors in ulcer healing: lessons from recent studies. J Physiol Paris 2000 94 : 77 81.
-
(2000)
J Physiol Paris
, vol.94
, pp. 77-81
-
-
Szabo, S.1
Vincze, A.2
-
44
-
-
33747727565
-
Integrative roles of transforming growth factor-alpha in the cytoprotection mechanisms of gastric mucosal injury
-
Kosone T, Takagi H, Kakizaki S, et al. Integrative roles of transforming growth factor-alpha in the cytoprotection mechanisms of gastric mucosal injury. BMC Gastroenterol 2006 6 : 22.
-
(2006)
BMC Gastroenterol
, vol.6
, pp. 22
-
-
Kosone, T.1
Takagi, H.2
Kakizaki, S.3
-
45
-
-
0347064072
-
COX-2 is essential for EGF induction of cell proliferation in gastric RGM1 cells
-
Sasaki E, Tominaga K, Watanabe T, et al. COX-2 is essential for EGF induction of cell proliferation in gastric RGM1 cells. Dig Dis Sci 2003 48 : 2257 62.
-
(2003)
Dig Dis Sci
, vol.48
, pp. 2257-2262
-
-
Sasaki, E.1
Tominaga, K.2
Watanabe, T.3
-
46
-
-
0037634338
-
Interaction of hepatocyte growth factor and non-steroidal anti-inflammatory drugs during gastric epithelial wound healing
-
Netzer P, Halter F, Ma TY, et al. Interaction of hepatocyte growth factor and non-steroidal anti-inflammatory drugs during gastric epithelial wound healing. Digestion 2003 67 : 118 28.
-
(2003)
Digestion
, vol.67
, pp. 118-128
-
-
Netzer, P.1
Halter, F.2
Ma, T.Y.3
-
47
-
-
2642553749
-
Trefoil factor family (TFF) peptides: Regulators of mucosal regeneration and repair, and more
-
Hoffmann W. Trefoil factor family (TFF) peptides: regulators of mucosal regeneration and repair, and more. Peptides 2004 25 : 727 30.
-
(2004)
Peptides
, vol.25
, pp. 727-730
-
-
Hoffmann, W.1
-
48
-
-
29344457901
-
Trefoil factors TFF (trefoil factor family) peptide-triggered signals promoting mucosal restitution
-
Hoffmann W. Trefoil factors TFF (trefoil factor family) peptide-triggered signals promoting mucosal restitution. Cell Mol Life Sci 2005 62 : 2932 8.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 2932-2938
-
-
Hoffmann, W.1
-
49
-
-
0842346328
-
PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells
-
Shimada T, Koitabashi A, Fujii Y, et al. PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells. FEBS Lett 2004 558 : 33 8.
-
(2004)
FEBS Lett
, vol.558
, pp. 33-38
-
-
Shimada, T.1
Koitabashi, A.2
Fujii, Y.3
-
50
-
-
17644403756
-
AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells
-
Berndt G, Grosser N, Hoogstraate J, Schroder H. AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells. Eur J Pharm Sci 2005 25 : 229 35.
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 229-235
-
-
Berndt, G.1
Grosser, N.2
Hoogstraate, J.3
Schroder, H.4
-
51
-
-
35848961446
-
Pharmacologic induction of heme oxygenase-1
-
Li C, Hossieny P, Wu BJ, Qawasmeh A, Beck K, Stocker R. Pharmacologic induction of heme oxygenase-1. Antioxid Redox Signal 2007 9 : 2227 39.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2227-2239
-
-
Li, C.1
Hossieny, P.2
Wu, B.J.3
Qawasmeh, A.4
Beck, K.5
Stocker, R.6
-
52
-
-
33745115862
-
Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide
-
Oh GS, Pae HO, Lee BS, et al. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med 2006 41 : 106 19.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 106-119
-
-
Oh, G.S.1
Pae, H.O.2
Lee, B.S.3
-
53
-
-
0030921169
-
Regulation of cyclooxygenase enzymes by nitric oxide
-
Salvemini D. Regulation of cyclooxygenase enzymes by nitric oxide. Cell Mol Life Sci 1997 53 : 576 82.
-
(1997)
Cell Mol Life Sci
, vol.53
, pp. 576-582
-
-
Salvemini, D.1
-
54
-
-
28444479852
-
Nitric oxide inhibits gastric acid secretion by increasing intraparietal cell levels of cGMP in isolated human gastric glands
-
Berg A, Redeen S, Grenegard M, Ericson AC, Sjostrand SE. Nitric oxide inhibits gastric acid secretion by increasing intraparietal cell levels of cGMP in isolated human gastric glands. Am J Physiol Gastrointest Liver Physiol 2005 289 : G1061 6.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Berg, A.1
Redeen, S.2
Grenegard, M.3
Ericson, A.C.4
Sjostrand, S.E.5
-
55
-
-
0035368275
-
Nitric oxide: Relation to integrity, injury, and healing of the gastric mucosa
-
Calatayud S, Barrachina D, Esplugues JV. Nitric oxide: relation to integrity, injury, and healing of the gastric mucosa. Microsc.Res.Tech. 2001 53 : 325 35.
-
(2001)
Microsc.Res.Tech.
, vol.53
, pp. 325-335
-
-
Calatayud, S.1
Barrachina, D.2
Esplugues, J.V.3
-
56
-
-
34548379105
-
The novel proangiogenic effect of hydrogen sulfide is dependent on Akt phosphorylation
-
Cai WJ, Wang MJ, Moore PK, Jin HM, Yao T, Zhu YC. The novel proangiogenic effect of hydrogen sulfide is dependent on Akt phosphorylation. Cardiovasc Res 2007 76 : 29 40.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 29-40
-
-
Cai, W.J.1
Wang, M.J.2
Moore, P.K.3
Jin, H.M.4
Yao, T.5
Zhu, Y.C.6
-
57
-
-
0034864543
-
Apoptosis of rat gastric mucosa and of primary cultures of gastric epithelial cells by indomethacin: Role of inducible nitric oxide synthase and interleukin-8
-
Imamine S, Akbar F, Mizukami Y, Matsui H, Onji M. Apoptosis of rat gastric mucosa and of primary cultures of gastric epithelial cells by indomethacin: role of inducible nitric oxide synthase and interleukin-8. Int J Exp Pathol 2001 82 : 221 9.
-
(2001)
Int J Exp Pathol
, vol.82
, pp. 221-229
-
-
Imamine, S.1
Akbar, F.2
Mizukami, Y.3
Matsui, H.4
Onji, M.5
-
58
-
-
0033033415
-
Activation of apoptotic caspase-3 and nitric oxide synthase-2 in gastric mucosal injury induced by indomethacin
-
Piotrowski J, Slomiany A, Slomiany BL. Activation of apoptotic caspase-3 and nitric oxide synthase-2 in gastric mucosal injury induced by indomethacin. Scand J Gastroenterol 1999 34 : 129 34.
-
(1999)
Scand J Gastroenterol
, vol.34
, pp. 129-134
-
-
Piotrowski, J.1
Slomiany, A.2
Slomiany, B.L.3
-
59
-
-
38349093979
-
Gastric damage induced by different doses of indomethacin in rats is variably affected by inhibiting iNOS or leukocyte infiltration
-
Souza MH, Mota JM, Oliveira RB, Cunha FQ. Gastric damage induced by different doses of indomethacin in rats is variably affected by inhibiting iNOS or leukocyte infiltration. Inflamm Res 2008 57 : 28 33.
-
(2008)
Inflamm Res
, vol.57
, pp. 28-33
-
-
Souza, M.H.1
Mota, J.M.2
Oliveira, R.B.3
Cunha, F.Q.4
-
60
-
-
0033635149
-
Role of endothelin-converting enzyme-1 in the suppression of constitutive nitric oxide synthase in rat gastric mucosal injury by indomethacin
-
Slomiany BL, Slomiany A. Role of endothelin-converting enzyme-1 in the suppression of constitutive nitric oxide synthase in rat gastric mucosal injury by indomethacin. Scand J Gastroenterol 2000 35 : 1131 6.
-
(2000)
Scand J Gastroenterol
, vol.35
, pp. 1131-1136
-
-
Slomiany, B.L.1
Slomiany, A.2
-
61
-
-
35548934557
-
Modulation of indomethacin-induced gastric injury by spermine and taurine in rats
-
Motawi TK, bd Elgawad HM, Shahin NN. Modulation of indomethacin-induced gastric injury by spermine and taurine in rats. J Biochem Mol Toxicol 2007 21 : 280 8.
-
(2007)
J Biochem Mol Toxicol
, vol.21
, pp. 280-288
-
-
Motawi, T.K.1
Bd Elgawad, H.M.2
Shahin, N.N.3
-
62
-
-
58149161550
-
Involvement of interleukin 18 in indomethacin-induced lesions of the gastric mucosa in adjuvant-induced arthritis rat
-
Nagai N, Fukuhata T, Ito Y, Usui S, Hirano K. Involvement of interleukin 18 in indomethacin-induced lesions of the gastric mucosa in adjuvant-induced arthritis rat. Toxicology 2009 255 : 124 30.
-
(2009)
Toxicology
, vol.255
, pp. 124-130
-
-
Nagai, N.1
Fukuhata, T.2
Ito, Y.3
Usui, S.4
Hirano, K.5
-
63
-
-
4644364924
-
Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: Correlation with endoscopic lesions and adverse reactions
-
Gallego-Sandin S, Novalbos J, Rosado A, et al. Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions. Dig Dis Sci 2004 49 : 1538 44.
-
(2004)
Dig Dis Sci
, vol.49
, pp. 1538-1544
-
-
Gallego-Sandin, S.1
Novalbos, J.2
Rosado, A.3
-
65
-
-
26844568431
-
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs
-
Fiorucci S, Antonelli E, Distrutti E, et al. Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs. Gastroenterology 2005 129 : 1210 24.
-
(2005)
Gastroenterology
, vol.129
, pp. 1210-1224
-
-
Fiorucci, S.1
Antonelli, E.2
Distrutti, E.3
-
66
-
-
34047142764
-
Hydrogen sulfide (H2S) - The third gas of interest for pharmacologists
-
Lowicka E, Beltowski J. Hydrogen sulfide (H2S) - the third gas of interest for pharmacologists. Pharmacol Rep 2007 59 : 4 24.
-
(2007)
Pharmacol Rep
, vol.59
, pp. 4-24
-
-
Lowicka, E.1
Beltowski, J.2
-
67
-
-
33845602529
-
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation
-
Zanardo RC, Brancaleone V, Distrutti E, Fiorucci S, Cirino G, Wallace JL. Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. FASEB J 2006 20 : 2118 20.
-
(2006)
FASEB J
, vol.20
, pp. 2118-2120
-
-
Zanardo, R.C.1
Brancaleone, V.2
Distrutti, E.3
Fiorucci, S.4
Cirino, G.5
Wallace, J.L.6
-
68
-
-
34247523663
-
Various stress proteins protect gastric mucosal cells against non-steroidal anti-inflammatory drugs
-
Mizushima T. Various stress proteins protect gastric mucosal cells against non-steroidal anti-inflammatory drugs. Inflammopharmacol 2007 15 : 67 73.
-
(2007)
Inflammopharmacol
, vol.15
, pp. 67-73
-
-
Mizushima, T.1
-
69
-
-
33947367704
-
Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions
-
Tanaka K, Tsutsumi S, Arai Y, et al. Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions. Mol Pharmacol 2007 71 : 985 93.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 985-993
-
-
Tanaka, K.1
Tsutsumi, S.2
Arai, Y.3
-
70
-
-
26044460211
-
Protective role of heat shock protein 27 in gastric mucosal injury
-
Ebert MP, Schafer C, Chen J, et al. Protective role of heat shock protein 27 in gastric mucosal injury. J Pathol 2005 207 : 177 84.
-
(2005)
J Pathol
, vol.207
, pp. 177-184
-
-
Ebert, M.P.1
Schafer, C.2
Chen, J.3
-
71
-
-
68949205369
-
Investigating the effects of NSAIDs on the expression of regulatory components of the polyamine pathway
-
Saunders FR, Hughes A, Wallace HM. Investigating the effects of NSAIDs on the expression of regulatory components of the polyamine pathway. Toxicology 2008 253 : 22 3.
-
(2008)
Toxicology
, vol.253
, pp. 22-23
-
-
Saunders, F.R.1
Hughes, A.2
Wallace, H.M.3
-
72
-
-
68949212653
-
Protective Effects of Polyamines on NSAID-induced injury and Apoptosis
-
Wang JY, Casero JR, eds. Totowa, NJ : Humana Press Inc
-
Wallace HM, Hughes A. Protective Effects of Polyamines on NSAID-induced injury and Apoptosis. In: Wang JY, Casero JR, eds. Polyamine Cell Signalling: Physiology, Pharmacology and Cancer Research. Totowa, NJ : Humana Press Inc, 2006 267 78.
-
(2006)
Polyamine Cell Signalling: Physiology, Pharmacology and Cancer Research
, pp. 267-278
-
-
Wallace, H.M.1
Hughes, A.2
-
73
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002 2 : 161 74.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
74
-
-
0033921878
-
Matrix metalloproteinases 2 and 9 in indomethacin-induced rat gastric ulcer
-
Lempinen M, Inkinen K, Wolff H, Ahonen J. Matrix metalloproteinases 2 and 9 in indomethacin-induced rat gastric ulcer. Eur Surg Res 2000 32 : 169 76.
-
(2000)
Eur Surg Res
, vol.32
, pp. 169-176
-
-
Lempinen, M.1
Inkinen, K.2
Wolff, H.3
Ahonen, J.4
-
75
-
-
0035877020
-
Remodeling of extracellular matrix in gastric ulceration
-
Shahin M, Konturek JW, Pohle T, Schuppan D, Herbst H, Domschke W. Remodeling of extracellular matrix in gastric ulceration. Microsc Res Tech 2001 53 : 396 408.
-
(2001)
Microsc Res Tech
, vol.53
, pp. 396-408
-
-
Shahin, M.1
Konturek, J.W.2
Pohle, T.3
Schuppan, D.4
Herbst, H.5
Domschke, W.6
-
76
-
-
15744405822
-
Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer
-
Swarnakar S, Ganguly K, Kundu P, Banerjee A, Maity P, Sharma AV. Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer. J Biol Chem 2005 280 : 9409 15.
-
(2005)
J Biol Chem
, vol.280
, pp. 9409-9415
-
-
Swarnakar, S.1
Ganguly, K.2
Kundu, P.3
Banerjee, A.4
Maity, P.5
Sharma, A.V.6
-
77
-
-
4043161974
-
Mitochondrial redox control of matrix metalloproteinases
-
Nelson KK, Melendez JA. Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med 2004 37 : 768 84.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 768-784
-
-
Nelson, K.K.1
Melendez, J.A.2
-
78
-
-
0037031833
-
Nonsteroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 via suppression of the ERK/Sp1-mediated transcription
-
Pan MR, Hung WC. Nonsteroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 via suppression of the ERK/Sp1-mediated transcription. J Biol Chem 2002 277 : 32775 80.
-
(2002)
J Biol Chem
, vol.277
, pp. 32775-32780
-
-
Pan, M.R.1
Hung, W.C.2
-
79
-
-
33747594750
-
Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants
-
Ganguly K, Kundu P, Banerjee A, Reiter RJ, Swarnakar S. Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants. Free Radic Biol Med 2006 41 : 911 25.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 911-925
-
-
Ganguly, K.1
Kundu, P.2
Banerjee, A.3
Reiter, R.J.4
Swarnakar, S.5
-
80
-
-
0033672109
-
Higher concentration of matrix-metalloproteinase 1 (interstitial collagenase) in H. pylori-compared to NSAID-induced gastric ulcers
-
Menges M, Chan CC, Zeitz M, Stallmach A. Higher concentration of matrix-metalloproteinase 1 (interstitial collagenase) in H. pylori-compared to NSAID-induced gastric ulcers. Z Gastroenterol 2000 38 : 887 91.
-
(2000)
Z Gastroenterol
, vol.38
, pp. 887-891
-
-
Menges, M.1
Chan, C.C.2
Zeitz, M.3
Stallmach, A.4
-
81
-
-
60749101830
-
Potential role for matrix metalloproteinase-3 in gastric ulcer healing
-
Tomita M, Ando T, Minami M, et al. Potential role for matrix metalloproteinase-3 in gastric ulcer healing. Digestion 2009 79 : 23 9.
-
(2009)
Digestion
, vol.79
, pp. 23-29
-
-
Tomita, M.1
Ando, T.2
Minami, M.3
-
82
-
-
14344250929
-
Melatonin as an organoprotector in the stomach and the pancreas
-
Jaworek J, Brzozowski T, Konturek SJ. Melatonin as an organoprotector in the stomach and the pancreas. J Pineal Res 2005 38 : 73 83.
-
(2005)
J Pineal Res
, vol.38
, pp. 73-83
-
-
Jaworek, J.1
Brzozowski, T.2
Konturek, S.J.3
-
83
-
-
25144509375
-
Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer
-
Ganguly K, Maity P, Reiter RJ, Swarnakar S. Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer. J Pineal Res 2005 39 : 307 15.
-
(2005)
J Pineal Res
, vol.39
, pp. 307-315
-
-
Ganguly, K.1
Maity, P.2
Reiter, R.J.3
Swarnakar, S.4
-
84
-
-
0036223640
-
Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan
-
Brzozowska I, Konturek PC, Brzozowski T, et al. Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan. J Pineal Res 2002 32 : 149 62.
-
(2002)
J Pineal Res
, vol.32
, pp. 149-162
-
-
Brzozowska, I.1
Konturek, P.C.2
Brzozowski, T.3
-
85
-
-
27744484922
-
Importance of the pineal gland, endogenous prostaglandins and sensory nerves in the gastroprotective actions of central and peripheral melatonin against stress-induced damage
-
Brzozowski T, Konturek PC, Zwirska-Korczala K, et al. Importance of the pineal gland, endogenous prostaglandins and sensory nerves in the gastroprotective actions of central and peripheral melatonin against stress-induced damage. J Pineal Res 2005 39 : 375 85.
-
(2005)
J Pineal Res
, vol.39
, pp. 375-385
-
-
Brzozowski, T.1
Konturek, P.C.2
Zwirska-Korczala, K.3
-
86
-
-
0037404885
-
Melatonin in the duodenal lumen is a potent stimulant of mucosal bicarbonate secretion
-
Sjoblom M, Flemstrom G. Melatonin in the duodenal lumen is a potent stimulant of mucosal bicarbonate secretion. J Pineal Res 2003 34 : 288 93.
-
(2003)
J Pineal Res
, vol.34
, pp. 288-293
-
-
Sjoblom, M.1
Flemstrom, G.2
-
87
-
-
49549117289
-
Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor L-tryptophan in rats
-
Konturek PC, Konturek SJ, Burnat G, Brzozowski T, Brzozowska I, Reiter RJ. Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor L-tryptophan in rats. J Pineal Res 2008 45 : 180 90.
-
(2008)
J Pineal Res
, vol.45
, pp. 180-190
-
-
Konturek, P.C.1
Konturek, S.J.2
Burnat, G.3
Brzozowski, T.4
Brzozowska, I.5
Reiter, R.J.6
-
89
-
-
51449084031
-
Melatonin and its precursor L-tryptophan prevent acute gastric mucosal damage induced by aspirin in humans
-
Konturek PC, Celinski K, Slomka M, et al. Melatonin and its precursor L-tryptophan prevent acute gastric mucosal damage induced by aspirin in humans. J Physiol Pharmacol 2008 59 (Suppl 2) 67 75.
-
(2008)
J Physiol Pharmacol
, vol.59
, Issue.SUPPL. 2
, pp. 67-75
-
-
Konturek, P.C.1
Celinski, K.2
Slomka, M.3
-
90
-
-
0034638766
-
Pharmacogenetics and adverse drug reactions
-
Meyer UA. Pharmacogenetics and adverse drug reactions. Lancet 2000 356 : 1667 71.
-
(2000)
Lancet
, vol.356
, pp. 1667-1671
-
-
Meyer, U.A.1
-
91
-
-
30044436433
-
Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2
-
Fries S, Grosser T, Price TS, et al. Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2. Gastroenterology 2006 130 : 55 64.
-
(2006)
Gastroenterology
, vol.130
, pp. 55-64
-
-
Fries, S.1
Grosser, T.2
Price, T.S.3
-
92
-
-
50649086561
-
Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers
-
Lopez-Rodriguez R, Novalbos J, Gallego-Sandin S, et al. Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers. Pharmacol Res 2008 58 : 77 84.
-
(2008)
Pharmacol Res
, vol.58
, pp. 77-84
-
-
Lopez-Rodriguez, R.1
Novalbos, J.2
Gallego-Sandin, S.3
-
93
-
-
0034818966
-
Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration?
-
Martin JH, Begg EJ, Kennedy MA, Roberts R, Barclay ML. Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration? Br J Clin Pharmacol 2001 51 : 627 30.
-
(2001)
Br J Clin Pharmacol
, vol.51
, pp. 627-630
-
-
Martin, J.H.1
Begg, E.J.2
Kennedy, M.A.3
Roberts, R.4
Barclay, M.L.5
-
94
-
-
10744225344
-
Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use
-
Martinez C, Blanco G, Ladero JM, et al. Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use. Br J Pharmacol 2004 141 : 205 8.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 205-208
-
-
Martinez, C.1
Blanco, G.2
Ladero, J.M.3
-
95
-
-
34547558049
-
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: Role of cytochrome P450 2C9 polymorphisms
-
Pilotto A, Seripa D, Franceschi M, et al. Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms. Gastroenterology 2007 133 : 465 71.
-
(2007)
Gastroenterology
, vol.133
, pp. 465-471
-
-
Pilotto, A.1
Seripa, D.2
Franceschi, M.3
-
96
-
-
35148859360
-
Association between genetic polymorphisms in the cyclooxygenase-1 gene promoter and peptic ulcers in Japan
-
Arisawa T, Tahara T, Shibata T, et al. Association between genetic polymorphisms in the cyclooxygenase-1 gene promoter and peptic ulcers in Japan. Int J Mol Med 2007 20 : 373 8.
-
(2007)
Int J Mol Med
, vol.20
, pp. 373-378
-
-
Arisawa, T.1
Tahara, T.2
Shibata, T.3
-
97
-
-
33846991602
-
Effect of a specific cyclooxygenase-gene polymorphism (A-842G/C50T) on the occurrence of peptic ulcer hemorrhage
-
van Oijen MG, Laheij RJ, Koetsier M, et al. Effect of a specific cyclooxygenase-gene polymorphism (A-842G/C50T) on the occurrence of peptic ulcer hemorrhage. Dig Dis Sci 2006 51 : 2348 52.
-
(2006)
Dig Dis Sci
, vol.51
, pp. 2348-2352
-
-
Van Oijen, M.G.1
Laheij, R.J.2
Koetsier, M.3
-
98
-
-
45249104350
-
A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin
-
Piazuelo E, Fuentes J, Garcfa-Gonzalez MA, Jimenez P, Lanas A. A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin. Clin Ther 2008 30 : 121 30.
-
(2008)
Clin Ther
, vol.30
, pp. 121-130
-
-
Piazuelo, E.1
Fuentes, J.2
Garcfa-Gonzalez, M.A.3
Jimenez, P.4
Lanas, A.5
-
99
-
-
28844447720
-
Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression
-
Kim KM, Song JJ, An JY, Kwon YT, Lee YJ. Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression. J Biol Chem 2005 280 : 41047 56.
-
(2005)
J Biol Chem
, vol.280
, pp. 41047-41056
-
-
Kim, K.M.1
Song, J.J.2
An, J.Y.3
Kwon, Y.T.4
Lee, Y.J.5
-
100
-
-
4644240763
-
Aspirin-induced mucosal cell death in human gastric cells: Evidence supporting an apoptotic mechanism
-
Power JJ, Dennis MS, Redlak MJ, Miller TA. Aspirin-induced mucosal cell death in human gastric cells: evidence supporting an apoptotic mechanism. Dig Dis Sci 2004 49 : 1518 25.
-
(2004)
Dig Dis Sci
, vol.49
, pp. 1518-1525
-
-
Power, J.J.1
Dennis, M.S.2
Redlak, M.J.3
Miller, T.A.4
-
102
-
-
58149312789
-
Aspirin-induced mucosal cell death in human gastric cells: Role of a caspase-independent mechanism
-
Leung AM, Redlak MJ, Miller TA. Aspirin-induced mucosal cell death in human gastric cells: role of a caspase-independent mechanism. Dig Dis Sci 2009 54 : 28 35.
-
(2009)
Dig Dis Sci
, vol.54
, pp. 28-35
-
-
Leung, A.M.1
Redlak, M.J.2
Miller, T.A.3
-
103
-
-
43049168293
-
NSAIDs and apoptosis
-
Jana NR. NSAIDs and apoptosis. Cell Mol Life Sci 2008 65 : 1295 301.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1295-1301
-
-
Jana, N.R.1
-
104
-
-
35348925963
-
NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis
-
Chiou SK, Mandayam S. NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis. Biochem Pharmacol 2007 74 : 1485 95.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1485-1495
-
-
Chiou, S.K.1
Mandayam, S.2
-
105
-
-
33749404802
-
Aspirin induces apoptosis through the inhibition of proteasome function
-
Dikshit P, Chatterjee M, Goswami A, Mishra A, Jana NR. Aspirin induces apoptosis through the inhibition of proteasome function. J Biol Chem 2006 281 : 29228 35.
-
(2006)
J Biol Chem
, vol.281
, pp. 29228-29235
-
-
Dikshit, P.1
Chatterjee, M.2
Goswami, A.3
Mishra, A.4
Jana, N.R.5
-
106
-
-
24744462508
-
Involvement of intracellular Ca2+ levels in nonsteroidal anti-inflammatory drug-induced apoptosis
-
Tanaka K, Tomisato W, Hoshino T, et al. Involvement of intracellular Ca2+ levels in nonsteroidal anti-inflammatory drug-induced apoptosis. J Biol Chem 2005 280 : 31059 67.
-
(2005)
J Biol Chem
, vol.280
, pp. 31059-31067
-
-
Tanaka, K.1
Tomisato, W.2
Hoshino, T.3
-
107
-
-
21744445898
-
Dual action of prostaglandin E2 on gastric acid secretion through different EP-receptor subtypes in the rat
-
Kato S, Aihara E, Yoshii K, Takeuchi K. Dual action of prostaglandin E2 on gastric acid secretion through different EP-receptor subtypes in the rat. Am J Physiol Gastrointest Liver Physiol 2005 289 : G64 9.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Kato, S.1
Aihara, E.2
Yoshii, K.3
Takeuchi, K.4
-
108
-
-
34948833723
-
Involvement of prostaglandin e receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach
-
Nishio H, Terashima S, Nakashima M, Aihara E, Takeuchi K. Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach. J Physiol Pharmacol 2007 58 : 407 21.
-
(2007)
J Physiol Pharmacol
, vol.58
, pp. 407-421
-
-
Nishio, H.1
Terashima, S.2
Nakashima, M.3
Aihara, E.4
Takeuchi, K.5
-
109
-
-
0034032989
-
The roles of prostaglandin e receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach
-
Araki H, Ukawa H, Sugawa Y, Yagi K, Suzuki K, Takeuchi K. The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach. Aliment Pharmacol Ther 2000 14 (Suppl 1) 116 24.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, Issue.SUPPL. 1
, pp. 116-124
-
-
Araki, H.1
Ukawa, H.2
Sugawa, Y.3
Yagi, K.4
Suzuki, K.5
Takeuchi, K.6
-
110
-
-
9344245196
-
Cyclooxygenase 1 is required for pH control at the mouse gastric surface
-
Baumgartner HK, Starodub OT, Joehl JS, Tackett L, Montrose MH. Cyclooxygenase 1 is required for pH control at the mouse gastric surface. Gut 2004 53 : 1751 7.
-
(2004)
Gut
, vol.53
, pp. 1751-1757
-
-
Baumgartner, H.K.1
Starodub, O.T.2
Joehl, J.S.3
Tackett, L.4
Montrose, M.H.5
-
111
-
-
33846191515
-
Involvement of cyclooxygenase-1, prostaglandin E2 and EP1 receptors in acid-induced
-
Takeuchi K, Aihara E, Sasaki Y, Nomura Y, Ise F. Involvement of cyclooxygenase-1, prostaglandin E2 and EP1 receptors in acid-induced. J Physiol Pharmacol 2006 57 : 661 76.
-
(2006)
J Physiol Pharmacol
, vol.57
, pp. 661-676
-
-
Takeuchi, K.1
Aihara, E.2
Sasaki, Y.3
Nomura, Y.4
Ise, F.5
-
113
-
-
25844483661
-
Duodenal secretion in humans mediated by the EP4 receptor subtype
-
Larsen R, Hansen MB, Bindslev N. Duodenal secretion in humans mediated by the EP4 receptor subtype. Acta Physiol Scand 2005 185 : 133 40.
-
(2005)
Acta Physiol Scand
, vol.185
, pp. 133-140
-
-
Larsen, R.1
Hansen, M.B.2
Bindslev, N.3
-
114
-
-
0042914797
-
Prostaglandin E receptor EP1 subtype but not prostacyclin IP receptor involved in mucosal blood flow response of mouse stomachs following barrier disruption
-
Komoike Y, Nakashima M, Nakagiri A, Takeuchi K. Prostaglandin E receptor EP1 subtype but not prostacyclin IP receptor involved in mucosal blood flow response of mouse stomachs following barrier disruption. Digestion 2003 67 : 186 94.
-
(2003)
Digestion
, vol.67
, pp. 186-194
-
-
Komoike, Y.1
Nakashima, M.2
Nakagiri, A.3
Takeuchi, K.4
-
115
-
-
0037371555
-
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors
-
Takeuchi K, Kato S, Takeeda M, Ogawa Y, Nakashima M, Matsumoto M. Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors. J Pharmacol Exp Ther 2003 304 : 1055 62.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1055-1062
-
-
Takeuchi, K.1
Kato, S.2
Takeeda, M.3
Ogawa, Y.4
Nakashima, M.5
Matsumoto, M.6
-
116
-
-
34347380335
-
Roles of cyclooxygenase-2 and prostaglandin e receptors in gastric mucosal defence in Helicobacter pylori-infected mice
-
Taira K, Watanabe T, Tanigawa T, et al. Roles of cyclooxygenase-2 and prostaglandin E receptors in gastric mucosal defence in Helicobacter pylori-infected mice. Inflammopharmacol 2009 15 : 132 8.
-
(2009)
Inflammopharmacol
, vol.15
, pp. 132-138
-
-
Taira, K.1
Watanabe, T.2
Tanigawa, T.3
-
117
-
-
0038306837
-
Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation
-
Hoshino T, Tsutsumi S, Tomisato W, Hwang HJ, Tsuchiya T, Mizushima T. Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation. J Biol Chem 2003 278 : 12752 8.
-
(2003)
J Biol Chem
, vol.278
, pp. 12752-12758
-
-
Hoshino, T.1
Tsutsumi, S.2
Tomisato, W.3
Hwang, H.J.4
Tsuchiya, T.5
Mizushima, T.6
-
118
-
-
0742286996
-
Role of prostaglandins in maintaining gastric mucus-cell permeability against acid exposure
-
Takezono Y, Joh T, Oshima T, et al. Role of prostaglandins in maintaining gastric mucus-cell permeability against acid exposure. J Lab Clin Med 2004 143 : 52 8.
-
(2004)
J Lab Clin Med
, vol.143
, pp. 52-58
-
-
Takezono, Y.1
Joh, T.2
Oshima, T.3
-
119
-
-
0035019326
-
Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: A study using rats and knockout mice
-
Takeuchi K, Araki H, Umeda M, Komoike Y, Suzuki K. Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice. J Pharmacol Exp Ther 2001 297 : 1160 5.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1160-1165
-
-
Takeuchi, K.1
Araki, H.2
Umeda, M.3
Komoike, Y.4
Suzuki, K.5
-
120
-
-
0035834283
-
The role of cellular migration in the repair process of gastric epithelial cells
-
Terano A, Sakata-Horie K, Shimada T, et al. The role of cellular migration in the repair process of gastric epithelial cells. Life Sci 2001 69 : 3083 9.
-
(2001)
Life Sci
, vol.69
, pp. 3083-3089
-
-
Terano, A.1
Sakata-Horie, K.2
Shimada, T.3
-
121
-
-
35349031088
-
Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors
-
Hatazawa R, Tanaka A, Tanigami M, et al. Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors. Am J Physiol Gastrointest Liver Physiol 2007 293 : G788 97.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
-
-
Hatazawa, R.1
Tanaka, A.2
Tanigami, M.3
-
122
-
-
31144475770
-
Roles of cyclooxygenase-2 and prostacyclin/IP receptors in mucosal defense against ischemia/reperfusion injury in mouse stomach
-
Kotani T, Kobata A, Nakamura E, Amagase K, Takeuchi K. Roles of cyclooxygenase-2 and prostacyclin/IP receptors in mucosal defense against ischemia/reperfusion injury in mouse stomach. J Pharmacol Exp Ther 2006 316 : 547 55.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 547-555
-
-
Kotani, T.1
Kobata, A.2
Nakamura, E.3
Amagase, K.4
Takeuchi, K.5
-
123
-
-
55949135789
-
Prostaglandins, NSAIDs, and gastric mucosal protection: Why doesn't the stomach digest itself?
-
Wallace JL. Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself? Physiol Rev 2008 88 : 1547 65.
-
(2008)
Physiol Rev
, vol.88
, pp. 1547-1565
-
-
Wallace, J.L.1
-
124
-
-
0037256309
-
Genetic variation in cyclooxygenase 1: Effects on response to aspirin
-
Halushka MK, Walker LP, Halushka PV. Genetic variation in cyclooxygenase 1: effects on response to aspirin. Clin Pharmacol Ther 2003 73 : 122 30.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 122-130
-
-
Halushka, M.K.1
Walker, L.P.2
Halushka, P.V.3
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