메뉴 건너뛰기




Volumn 12, Issue 4, 2014, Pages 342-352

Noradrenergic regulation of glial activation: Molecular mechanisms and therapeutic implications

Author keywords

Alzheimer s disease; Amyloid; EAE; GFAP; Locus coeruleus; Multiple sclerosis; Noradrenaline; Review; Transgenic mice; Tyrosine hydroxylase

Indexed keywords

ATOMOXETINE; THREO 3, 4 DIHYDROXYPHENYLSERINE; UNCLASSIFIED DRUG;

EID: 84911480443     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X12666140828220938     Document Type: Article
Times cited : (44)

References (124)
  • 1
    • 84880477026 scopus 로고    scopus 로고
    • Functional neuroanatomy of the central noradrenergic system
    • Szabadi, E. Functional neuroanatomy of the central noradrenergic system. J. Psychopharmacol., 2013, 27, 659-693. doi: 10. 1177/0269881113490326.
    • (2013) J. Psychopharmacol , vol.27 , pp. 659-693
    • Szabadi, E.1
  • 2
    • 77956226559 scopus 로고    scopus 로고
    • Adrenoceptors in brain: Cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i
    • Hertz, L.; Lovatt, D.; Goldman, S. A.; Nedergaard, M. Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i. Neurochem. Int., 2010, 57, 411-420. DOI: 10. 1016/j. neuint. 2010. 03. 019.
    • (2010) Neurochem. Int , vol.57 , pp. 411-420
    • Hertz, L.1    Lovatt, D.2    Goldman, S.A.3    Nedergaard, M.4
  • 3
    • 84871450029 scopus 로고    scopus 로고
    • Norepinephrine: A neuromodulator that boosts the function of multiple cell types to optimize CNS performance
    • O'Donnell, J.; Zeppenfeld, D.; McConnell, E.; Pena, S.; Nedergaard, M. Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance. Neurochem. Res., 2012, 37, 2496-2512. DOI10. 1007/s11064-012-0818-x.
    • (2012) Neurochem. Res , vol.37 , pp. 2496-2512
    • O'Donnell, J.1    Zeppenfeld, D.2    McConnell, E.3    Pena, S.4    Nedergaard, M.5
  • 4
    • 84893734691 scopus 로고    scopus 로고
    • Dynamics of beta-adrenergic/cAMP signaling and morphological changes in cultured astrocytes
    • Vardjan, N.; Kreft, M.; Zorec, R. Dynamics of beta-adrenergic/cAMP signaling and morphological changes in cultured astrocytes. Glia, 2014, 62, 566-579. DOI: 10. 1002/glia. 22626.
    • (2014) Glia , vol.62 , pp. 566-579
    • Vardjan, N.1    Kreft, M.2    Zorec, R.3
  • 5
    • 69349103856 scopus 로고    scopus 로고
    • ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors
    • Du T.; Li B.; Liu S.; Zang P.; Prevot V.; Hertz L.; Peng L. ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors. Neurochem. Int., 2009, 55, 593-600. DOI: 10. 1016/j. neuint. 2009. 05. 016.
    • (2009) Neurochem. Int , vol.55 , pp. 593-600
    • Du, T.1    Li, B.2    Liu, S.3    Zang, P.4    Prevot, V.5    Hertz, L.6    Peng, L.7
  • 6
    • 0028344765 scopus 로고
    • Clonidine enhances astrocytic glutamine uptake by authentic alpha 2-adrenoceptor stimulation
    • Huang, R. and Hertz, L. Clonidine enhances astrocytic glutamine uptake by authentic alpha 2-adrenoceptor stimulation. Neuroreport, 1994, 5, 632-634. DOI: 10. 1097/00001756-199401000-00025.
    • (1994) Neuroreport , vol.5 , pp. 632-634
    • Huang, R.1    Hertz, L.2
  • 7
    • 0026452954 scopus 로고
    • Dexmedetomidine, a potent and highly specific alpha 2 agonist, evokes cytosolic calcium surge in astrocytes but not in neurons
    • Zhao, Z.; Code, W. E.; Hertz, L. Dexmedetomidine, a potent and highly specific alpha 2 agonist, evokes cytosolic calcium surge in astrocytes but not in neurons. Neuropharmacology, 1992, 31, 1077-1079. DOI: 10. 1016/0028-3908(92)90111-2.
    • (1992) Neuropharmacology , vol.31 , pp. 1077-1079
    • Zhao, Z.1    Code, W.E.2    Hertz, L.3
  • 8
    • 0027763898 scopus 로고
    • Neurotransmitters regulate energy metabolism in astrocytes: Implications for the metabolic trafficking between neural cells
    • Magistretti, P. J.; Sorg, O.; Yu, N.; Martin, J. L.; Pellerin, L. Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells. Dev. Neurosci., 1993, 15, 306-312. DOI: 10.1159/000111349.
    • (1993) Dev. Neurosci , vol.15 , pp. 306-312
    • Magistretti, P.J.1    Sorg, O.2    Yu, N.3    Martin, J.L.4    Pellerin, L.5
  • 9
    • 0025674614 scopus 로고
    • Effect of adrenergic agonists on glycogenolysis in primary cultures of astrocytes
    • Subbarao, K. V. and Hertz, L. Effect of adrenergic agonists on glycogenolysis in primary cultures of astrocytes. Brain Res., 1990, 536, 220-226. DOI: 10. 1016/0006-8993(90)90028-A.
    • (1990) Brain Res , vol.536 , pp. 220-226
    • Subbarao, K.V.1    Hertz, L.2
  • 10
    • 0034672474 scopus 로고    scopus 로고
    • Beta-agonists regulate Na, K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways
    • Pesce, L.; Guerrero, C.; Comellas, A.; Ridge, K. M.; Sznajder, J. I. beta-agonists regulate Na, K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways. FEBS Lett., 2000, 486, 310-314. DOI: 10. 1016/S0014-5793(00)02298-5.
    • (2000) FEBS Lett , vol.486 , pp. 310-314
    • Pesce, L.1    Guerrero, C.2    Comellas, A.3    Ridge, K.M.4    Sznajder, J.I.5
  • 11
    • 0031081781 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors
    • Minghetti, L.; Nicolini, A.; Polazzi, E.; Creminon C.; Maclouf J.; Levi, G. Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors. Glia, 1997, 19, 152-160. DOI: 10. 1002/(SICI)1098-1136(199702)19: 2<152:: AID-GLIA>63. 0. CO; 2-2.
    • (1997) Glia , vol.19 , pp. 152-160
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Creminon, C.4    Maclouf, J.5    Levi, G.6
  • 12
    • 0032779378 scopus 로고    scopus 로고
    • Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP
    • PMID: 10593859
    • Galea, E. and Feinstein, D. L. Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP. FASEB J., 1999, 13, 2125-2137. PMID: 10593859.
    • (1999) FASEB J , vol.13 , pp. 2125-2137
    • Galea, E.1    Feinstein, D.L.2
  • 13
    • 0031022127 scopus 로고    scopus 로고
    • Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide produciton and protects against the development of vascular hyporeactivity in endotoxaemia
    • Szabo, C.; Hasko, G.; Zingarelli, B.; Nemeth, Z. H.; Salzman, A. L.; Kvetan, V.; Pastores, S. M.; Vizi, E. S. Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide produciton and protects against the development of vascular hyporeactivity in endotoxaemia. Immunology, 1997, 90, 95-100. DOI: 10. 1046/j. 1365-2567. 1997. 00137. x.
    • (1997) Immunology , vol.90 , pp. 95-100
    • Szabo, C.1    Hasko, G.2    Zingarelli, B.3    Nemeth, Z.H.4    Salzman, A.L.5    Kvetan, V.6    Pastores, S.M.7    Vizi, E.S.8
  • 14
    • 0023869747 scopus 로고
    • Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms
    • PubMed ID2829222
    • Frohman, E. M.; Vayuvegula, B.; Gupta, S.; van den, N. S. Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms. Proc. Natl. Acad. Sci. U. S. A, 1988, 85, 1292-1296. PubMed ID2829222.
    • (1988) Proc. Natl. Acad. Sci. U.S. A , vol.85 , pp. 1292-1296
    • Frohman, E.M.1    Vayuvegula, B.2    Gupta, S.3    van den, N.S.4
  • 15
    • 0027155514 scopus 로고
    • Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures
    • Feinstein, D. L.; Galea, E.; Reis, D. J. Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. J. Neurochem., 1993, 60, 1945-1948. DOI: 10. 1111/j. 1471-4159. 1993. tb13425. x.
    • (1993) J. Neurochem , vol.60 , pp. 1945-1948
    • Feinstein, D.L.1    Galea, E.2    Reis, D.J.3
  • 16
    • 4344605751 scopus 로고    scopus 로고
    • Inhibition of microglial inflammatory responses by norepinephrine: Effects on nitric oxide and interleukin-1beta production
    • Dello, R. C.; Boullerne, A. I.; Gavrilyuk, V.; Feinstein, D. L. Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1beta production. J. Neuroinflammation, 2004, 1, 9. DOI: 10. 1186/1742-2094-1-9.
    • (2004) J. Neuroinflammation , vol.1 , pp. 9
    • Dello, R.C.1    Boullerne, A.I.2    Gavrilyuk, V.3    Feinstein, D.L.4
  • 17
    • 77956228094 scopus 로고    scopus 로고
    • Astrocytes as potential targets to suppress inflammatory demyelinating lesions in multiple sclerosis
    • De Keyser, J.; Laureys, G.; Demol, F.; Wilczak, N.; Mostert, J.; Clinckers, R. Astrocytes as potential targets to suppress inflammatory demyelinating lesions in multiple sclerosis. Neurochem. Int., 2010, 57, 446-450. DOI: 10. 1016/j. neuint. 2010. 02. 012.
    • (2010) Neurochem. Int , vol.57 , pp. 446-450
    • De Keyser, J.1    Laureys, G.2    Demol, F.3    Wilczak, N.4    Mostert, J.5    Clinckers, R.6
  • 19
    • 0034935988 scopus 로고    scopus 로고
    • A 27-bp region of the inducible nitric oxide synthase promoter regulates expression in glial cells
    • Gavrilyuk, V.; Horvath, P.; Weinberg, G.; Feinstein, D. L. A 27-bp region of the inducible nitric oxide synthase promoter regulates expression in glial cells. J. Neurochem., 2001, 78, 129-140. DOI: 10. 1046/j. 1471-4159. 2001. 00375. x.
    • (2001) J. Neurochem , vol.78 , pp. 129-140
    • Gavrilyuk, V.1    Horvath, P.2    Weinberg, G.3    Feinstein, D.L.4
  • 20
    • 25444432765 scopus 로고    scopus 로고
    • Norepinephrine protects cortical neurons against microglial-induced cell death
    • Madrigal, J. L.; Feinstein, D. L.; Dello, R. C. Norepinephrine protects cortical neurons against microglial-induced cell death. J. Neurosci. Res., 2005, 81, 390-396. DOI: 10. 1002/jnr. 20481.
    • (2005) J. Neurosci. Res , vol.81 , pp. 390-396
    • Madrigal, J.L.1    Feinstein, D.L.2    Dello, R.C.3
  • 21
    • 0032217094 scopus 로고    scopus 로고
    • Neuroprotective effects of the alpha2-adrenoceptor antagonists, (+)-efaroxan and (+/-)-idazoxan, against quinolinic acid-induced lesions of the rat striatum
    • Martel, J.; Chopin, P.; Colpaert, F.; Marien, M. Neuroprotective effects of the alpha2-adrenoceptor antagonists, (+)-efaroxan and (+/-)-idazoxan, against quinolinic acid-induced lesions of the rat striatum. Exp. Neurol., 1998, 154, 595-601. DOI: 10. 1006/exnr. 1998. 6942.
    • (1998) Exp. Neurol , vol.154 , pp. 595-601
    • Martel, J.1    Chopin, P.2    Colpaert, F.3    Marien, M.4
  • 22
    • 0025006009 scopus 로고
    • Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: Influence of time of administration and possible mechanisms of action
    • Gustafson, I.; Westerberg, E.; Wieloch, T. Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action. J Cereb. Blood Flow Metab, 1990, 10, 885-894. doi: 10. 1038/jcbfm. 1990. 145.
    • (1990) J Cereb. Blood Flow Metab , vol.10 , pp. 885-894
    • Gustafson, I.1    Westerberg, E.2    Wieloch, T.3
  • 23
    • 22044445939 scopus 로고    scopus 로고
    • Activation of noradrenergic transmission by alpha2-adrenoceptor antagonists counteracts deafferentation-induced neuronal death and cell proliferation in the adult mouse olfactory bulb
    • Veyrac A.; Didier A.; Colpaert F.; Jourdan F.; Marien M. Activation of noradrenergic transmission by alpha2-adrenoceptor antagonists counteracts deafferentation-induced neuronal death and cell proliferation in the adult mouse olfactory bulb. Exp. Neurol., 2005, 194, 444-456. DOI: 10. 1016/j. expneurol. 2005. 03. 004.
    • (2005) Exp. Neurol , vol.194 , pp. 444-456
    • Veyrac, A.1    Didier, A.2    Colpaert, F.3    Jourdan, F.4    Marien, M.5
  • 25
    • 78650810278 scopus 로고    scopus 로고
    • Chronic treatment with the alpha2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APPxPS1 transgenic mice without altering beta-amyloid plaque load or astrocytosis
    • Scullion, G. A.; Kendall, D. A.; Marsden, C. A.; Sunter, D.; Pardon, M. C. Chronic treatment with the alpha2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APPxPS1 transgenic mice without altering beta-amyloid plaque load or astrocytosis. Neuropharmacology, 2011, 60, 223-234. DOI: 10. 1016/j. neuropharm. 2010. 09. 002.
    • (2011) Neuropharmacology , vol.60 , pp. 223-234
    • Scullion, G.A.1    Kendall, D.A.2    Marsden, C.A.3    Sunter, D.4    Pardon, M.C.5
  • 26
    • 77649338803 scopus 로고    scopus 로고
    • Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge
    • O'Sullivan, J. B.; Ryan, K. M.; Harkin, A.; Connor, T. J. Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge. J. Neuroimmunol., 2010, 220, 34-42. DOI: 10. 1016/j. jneuroim. 2009. 12. 007.
    • (2010) J. Neuroimmunol , vol.220 , pp. 34-42
    • O'Sullivan, J.B.1    Ryan, K.M.2    Harkin, A.3    Connor, T.J.4
  • 27
    • 77953285381 scopus 로고    scopus 로고
    • Noradrenaline acting at beta-adrenoceptors induces expression of IL-1beta and its negative regulators IL-1 ra and IL-1RII, and drives an overall antiinflammatory phenotype in rat cortex
    • McNamee, E. N.; Griffin, E. W.; Ryan, K. M.; Ryan, K. J.; Heffernan S.; Harkin, A.; Connor, T. J. Noradrenaline acting at beta-adrenoceptors induces expression of IL-1beta and its negative regulators IL-1 ra and IL-1RII, and drives an overall antiinflammatory phenotype in rat cortex. Neuropharmacology, 2010, 59, 37-48. DOI: 10. 1016/j. neuropharm. 2010. 03. 014.
    • (2010) Neuropharmacology , vol.59 , pp. 37-48
    • McNamee, E.N.1    Griffin, E.W.2    Ryan, K.M.3    Ryan, K.J.4    Heffernan, S.5    Harkin, A.6    Connor, T.J.7
  • 28
    • 34250648917 scopus 로고    scopus 로고
    • Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide
    • Hashioka, S.; Klegeris, A.; Monji A.; Kato, T.; Sawada, M.; McGeer P. L.; Kanba S. Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide. Exp. Neurol., 2007, 206, 33-42. DOI: 10. 1016/j. expneurol. 2007. 03. 022.
    • (2007) Exp. Neurol , vol.206 , pp. 33-42
    • Hashioka, S.1    Klegeris, A.2    Monji, A.3    Kato, T.4    Sawada, M.5    McGeer, P.L.6    Kanba, S.7
  • 29
    • 0032863708 scopus 로고    scopus 로고
    • Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression
    • Russo-Neustadt, A.; Beard, R. C.; Cotman, C. W. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology, 1999, 21, 679-682. doi: 10. 1016/S0893-133X(99)00059-7.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 679-682
    • Russo-Neustadt, A.1    Beard, R.C.2    Cotman, C.W.3
  • 30
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • PMID: 11124987
    • Malberg, J. E.; Eisch, A. J.; Nestler, E. J.; Duman, R. S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci., 2000, 20, 9104-9110. PMID: 11124987.
    • (2000) J. Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 31
    • 28444437362 scopus 로고    scopus 로고
    • Pharmacotherapy of attention-deficit hyperactivity disorder in children and adolescents: Update on new stimulant preparations, atomoxetine, and novel treatments
    • Prince, J. B. Pharmacotherapy of attention-deficit hyperactivity disorder in children and adolescents: update on new stimulant preparations, atomoxetine, and novel treatments. Child Adolesc. Psychiatr. Clin. N. Am., 2006, 15, 13-50. DOI: 10. 1016/j. chc. 2005. 08. 002.
    • (2006) Child Adolesc. Psychiatr. Clin. N. Am , vol.15 , pp. 13-50
    • Prince, J.B.1
  • 33
    • 69449085737 scopus 로고    scopus 로고
    • Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with Alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study
    • Mohs, R. C.; Shiovitz, T. M.; Tariot, P. N.; Porsteinsson, A. P.; Baker, K. D.; Feldman, P. D. Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with Alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study. Am. J. Geriatr. Psychiatry, 2009, 17, 752-759. doi: 10. 1097/JGP. 0b013e3181aad585.
    • (2009) Am. J. Geriatr. Psychiatry , vol.17 , pp. 752-759
    • Mohs, R.C.1    Shiovitz, T.M.2    Tariot, P.N.3    Porsteinsson, A.P.4    Baker, K.D.5    Feldman, P.D.6
  • 34
    • 33847770509 scopus 로고    scopus 로고
    • L-Dihydroxyphenylserine (L-DOPS): A norepinephrine prodrug
    • Goldstein, D. S. L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug. Cardiovasc. Drug Rev., 2006, 24, 189-203. DOI: 10. 1111/j. 1527-3466. 2006. 00189. x.
    • (2006) Cardiovasc. Drug Rev , vol.24 , pp. 189-203
    • Goldstein, D.S.1
  • 35
    • 0034532928 scopus 로고    scopus 로고
    • The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3, 4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models
    • PMID: 11144954
    • Nakamura, K.; Ahmed, M.; Barr, E.; Leiden, J. M.; Kang, U. J. The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3, 4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models. Cell Transplant., 1999, 9, 567-576. PMID: 11144954.
    • (1999) Cell Transplant , vol.9 , pp. 567-576
    • Nakamura, K.1    Ahmed, M.2    Barr, E.3    Leiden, J.M.4    Kang, U.J.5
  • 37
    • 84861878510 scopus 로고    scopus 로고
    • The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease
    • Kalinin, S.; Polak, P. E.; Lin, S. X.; Sakharkar, A. J.; Pandey, S. C.; Feinstein, D. L. The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease. Neurobiol. Aging, 2012, 33, 1651-1663. DOI: 10. 1016/j. neurobiolaging. 2011. 04. 012.
    • (2012) Neurobiol. Aging , vol.33 , pp. 1651-1663
    • Kalinin, S.1    Polak, P.E.2    Lin, S.X.3    Sakharkar, A.J.4    Pandey, S.C.5    Feinstein, D.L.6
  • 38
    • 0028207960 scopus 로고
    • Different metabolism of norepinephrine and epinephrine by catechol-O-methyltransferase and monoamine oxidase in rats
    • PMID: 8138937
    • Eisenhofer, G. and Finberg, J. P. Different metabolism of norepinephrine and epinephrine by catechol-O-methyltransferase and monoamine oxidase in rats. J. Pharmacol. Exp. Ther., 1994, 268, 1242-1251. PMID: 8138937.
    • (1994) J. Pharmacol. Exp. Ther , vol.268 , pp. 1242-1251
    • Eisenhofer, G.1    Finberg, J.P.2
  • 39
    • 22444439252 scopus 로고    scopus 로고
    • Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons
    • Huang, G.; Dragan, M.; Freeman, D.; Wilson, J. X. Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons. Glia, 2005, 51, 47-55. DOI: 10. 1002/glia. 20185.
    • (2005) Glia , vol.51 , pp. 47-55
    • Huang, G.1    Dragan, M.2    Freeman, D.3    Wilson, J.X.4
  • 40
    • 34848926047 scopus 로고    scopus 로고
    • Increased catechol-O-methyltrans-ferase activity and protein expression in OX-42-positive cells in the substantia nigra after lipopolysaccharide microinfusion
    • Helkamaa, T.; Reenila, I.; Tuominen, R. K.; Soinila, S.; Vaananen, A.; Tilgmann, C.; Rauhala, P. Increased catechol-O-methyltrans-ferase activity and protein expression in OX-42-positive cells in the substantia nigra after lipopolysaccharide microinfusion. Neurochem. Int., 2007, 51, 412-423. DOI: 10. 1016/j. neuint. 2007. 04. 020.
    • (2007) Neurochem. Int , vol.51 , pp. 412-423
    • Helkamaa, T.1    Reenila, I.2    Tuominen, R.K.3    Soinila, S.4    Vaananen, A.5    Tilgmann, C.6    Rauhala, P.7
  • 41
    • 77953104962 scopus 로고    scopus 로고
    • Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice
    • Myohanen, T. T.; Schendzielorz, N.; Mannisto, P. T. Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice. J. Neurochem., 2010, 113, 1632-1643. DOI: 10. 1111/j. 1471-4159. 2010. 06723. x.
    • (2010) J. Neurochem , vol.113 , pp. 1632-1643
    • Myohanen, T.T.1    Schendzielorz, N.2    Mannisto, P.T.3
  • 42
    • 77951278327 scopus 로고    scopus 로고
    • Levodopa/carbidopa and entacapone in the treatment of Parkinson's disease: Efficacy, safety and patient preference. Patient
    • Muller, T. Levodopa/carbidopa and entacapone in the treatment of Parkinson's disease: efficacy, safety and patient preference. Patient. Prefer. Adherence., 2009, 3, 51-59. DOI http://dx. doi. org/10. 2147/ PPA. S4084.
    • (2009) Prefer. Adherence , vol.3 , pp. 51-59
    • Muller, T.1
  • 43
    • 0027250362 scopus 로고
    • Therapy with central active catechol-O-methyltransferase (COMT)-inhibitors: Is addition of monoamine oxidase (MAO)-inhibitors necessary to slow progress of neurodegenerative disorders?
    • Muller, T.; Kuhn, W.; Przuntek, H. Therapy with central active catechol-O-methyltransferase (COMT)-inhibitors: is addition of monoamine oxidase (MAO)-inhibitors necessary to slow progress of neurodegenerative disorders? J. Neural Transm. Gen. Sect., 1992, 92, 187-195. DOI10. 1007/BF01244877.
    • (1992) J. Neural Transm. Gen. Sect , vol.92 , pp. 187-195
    • Muller, T.1    Kuhn, W.2    Przuntek, H.3
  • 44
    • 70849110410 scopus 로고    scopus 로고
    • Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity
    • McNamee, E. N.; Ryan, K. M.; Kilroy, D.; Connor, T. J. Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity. Eur. J. Pharmacol., 2010, 626, 219-228. DOI: 10. 1016/j. ejphar. 2009. 09. 054.
    • (2010) Eur. J. Pharmacol , vol.626 , pp. 219-228
    • McNamee, E.N.1    Ryan, K.M.2    Kilroy, D.3    Connor, T.J.4
  • 45
    • 58149392087 scopus 로고    scopus 로고
    • Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline
    • Madrigal, J. L.; Leza, J. C.; Polak, P.; Kalinin, S.; Fein stein, D. L. Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J. Neurosci., 2009, 29, 263-267. doi: 10. 1523/JNEUROSCI. 4926-08. 2009.
    • (2009) J. Neurosci , vol.29 , pp. 263-267
    • Madrigal, J.L.1    Leza, J.C.2    Polak, P.3    Kalinin, S.4    Fein stein, D.L.5
  • 46
    • 79955945545 scopus 로고    scopus 로고
    • Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson's disease
    • Mangano, E. N.; Peters, S.; Litteljohn, D.; So, R.; Bethune, C.; Bobyn J.; Clarke M.; Hayley S. Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson's disease. Neurobiol. Dis., 2011, 43, 99-112. DOI: 10. 1016/j. nbd. 2011. 02. 011.
    • (2011) Neurobiol. Dis , vol.43 , pp. 99-112
    • Mangano, E.N.1    Peters, S.2    Litteljohn, D.3    So, R.4    Bethune, C.5    Bobyn, J.6    Clarke, M.7    Hayley, S.8
  • 48
    • 84888369519 scopus 로고    scopus 로고
    • GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine intoxicated mice
    • Kosloski, L. M.; Kosmacek, E. A.; Olson, K. E.; Mosley, R. L.; Gendelman, H. E. GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine intoxicated mice. J. Neuroimmunol., 2013, 265, 1-10. DOI: 10. 1016/j jneuroim. 2013. 10. 009.
    • (2013) J. Neuroimmunol , vol.265 , pp. 1-10
    • Kosloski, L.M.1    Kosmacek, E.A.2    Olson, K.E.3    Mosley, R.L.4    Gendelman, H.E.5
  • 49
    • 0030275956 scopus 로고    scopus 로고
    • Immunogenetic mechanisms in autoimmune processes: Disorders of immune regulatory mechanisms, genetic determination of autoimmunity, effector mechanisms of autoimmune processes and their therapy
    • PMID: 9117429
    • Buc, M. [Immunogenetic mechanisms in autoimmune processes: disorders of immune regulatory mechanisms, genetic determination of autoimmunity, effector mechanisms of autoimmune processes and their therapy]. Bratisl. Lek. Listy, 1996, 97, 660-668. PMID: 9117429.
    • (1996) Bratisl. Lek. Listy , vol.97 , pp. 660-668
    • Buc, M.1
  • 50
    • 84862733981 scopus 로고    scopus 로고
    • Regulatory T cells in the central nervous system
    • Lowther, D. E. and Hafler, D. A. Regulatory T cells in the central nervous system. Immunol. Rev., 2012, 248, 156-169. DOI: 10. 1111/j. 1600-065X. 2012. 01130. x.
    • (2012) Immunol. Rev , vol.248 , pp. 156-169
    • Lowther, D.E.1    Hafler, D.A.2
  • 51
    • 79955784400 scopus 로고    scopus 로고
    • MCP-1: Chemoattractant with a role beyond immunity: A review
    • Yadav, A.; Saini, V.; Arora S. MCP-1: chemoattractant with a role beyond immunity: a review. Clin. Chim. Acta, 2010, 411, 1570-1579. DOI: 10. 1016/j. cca. 2010. 07. 006.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1570-1579
    • Yadav, A.1    Saini, V.2    Arora, S.3
  • 52
    • 79959835836 scopus 로고    scopus 로고
    • CCL2/MCP-1 modulation of microglial activation and proliferation
    • Hinojosa, A. E.; Garcia-Bueno, B.; Leza, J. C.; Madrigal, J. L. CCL2/MCP-1 modulation of microglial activation and proliferation. J. Neuroinflammation., 2011, 8, 77. doi: 10. 1186/1742-2094-8-77.
    • (2011) J. Neuroinflammation , vol.8 , pp. 77
    • Hinojosa, A.E.1    Garcia-Bueno, B.2    Leza, J.C.3    Madrigal, J.L.4
  • 53
    • 77949721179 scopus 로고    scopus 로고
    • Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs
    • Madrigal, J. L.; Garcia-Bueno, B.; Hinojosa, A. E.; Polak, P.; Feinstein, D. L.; Leza J. C. Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. J. Neurochem., 2010, 113, 543-551. DOI: 10. 1111/j. 1471-4159. 2010. 06623. x.
    • (2010) J. Neurochem , vol.113 , pp. 543-551
    • Madrigal, J.L.1    Garcia-Bueno, B.2    Hinojosa, A.E.3    Polak, P.4    Feinstein, D.L.5    Leza, J.C.6
  • 54
    • 0034617343 scopus 로고    scopus 로고
    • Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture
    • Bruno V.; Copani A.; Besong G.; Scoto G.; Nicoletti F. Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture. Eur. J. Pharmacol., 2000, 399, 117-121. DOI: 10. 1016/S0014-2999(00) 00367-8.
    • (2000) Eur. J. Pharmacol , vol.399 , pp. 117-121
    • Bruno, V.1    Copani, A.2    Besong, G.3    Scoto, G.4    Nicoletti, F.5
  • 55
    • 84873386607 scopus 로고    scopus 로고
    • Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression
    • Bray J. G.; Reyes K. C.; Roberts A. J.; Ransohoff R. M.; Gruol D. L. Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Neuropharmacology, 2013, 67, 115-125. DOI: 10. 1016/j. neuropharm. 2012. 11. 007.
    • (2013) Neuropharmacology , vol.67 , pp. 115-125
    • Bray, J.G.1    Reyes, K.C.2    Roberts, A.J.3    Ransohoff, R.M.4    Gruol, D.L.5
  • 56
    • 84884208321 scopus 로고    scopus 로고
    • Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases
    • Bose, S. and Cho, J. Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases. Arch. Pharm. Res., 2013, 36, 1039-1050. DOI10. 1007/s12272-013-0161-z.
    • (2013) Arch. Pharm. Res , vol.36 , pp. 1039-1050
    • Bose, S.1    Cho, J.2
  • 57
    • 84872354623 scopus 로고    scopus 로고
    • CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease
    • Kiyota, T.; Gendelman, H. E.; Weir, R. A.; Higgins, E. E.; Zhang, G.; Jain, M. CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease. Neurobiol. Aging, 2013, 34, 1060-1068. DOI: 10. 1016/j. neurobiolaging. 2012. 08. 009.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1060-1068
    • Kiyota, T.1    Gendelman, H.E.2    Weir, R.A.3    Higgins, E.E.4    Zhang, G.5    Jain, M.6
  • 58
    • 79955775349 scopus 로고    scopus 로고
    • CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease
    • Naert, G. and Rivest, S. CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease. J. Neurosci., 2011, 31, 6208-6220. DOI: 10. 1016/j. neurobiolaging. 2012. 08. 009.
    • (2011) J. Neurosci , vol.31 , pp. 6208-6220
    • Naert, G.1    Rivest, S.2
  • 59
    • 0023252287 scopus 로고
    • Regulation of nerve growth factor synthesis/secretion by catecholamine in cultured mouse astroglial cells
    • Furukawa, S.; Furukawa, Y.; Satoyoshi, E.; Hayashi, K. Regulation of nerve growth factor synthesis/secretion by catecholamine in cultured mouse astroglial cells. Biochem. Biophys. Res. Commun., 1987, 147, 1048-1054. DOI: 10. 1016/S0006-291X(87)80176-6.
    • (1987) Biochem. Biophys. Res. Commun , vol.147 , pp. 1048-1054
    • Furukawa, S.1    Furukawa, Y.2    Satoyoshi, E.3    Hayashi, K.4
  • 60
    • 0035341498 scopus 로고    scopus 로고
    • Neuroprotection mediated by glial cell line-derived neurotrophic factor: Involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway
    • PMID: 11312287
    • Nicole, O.; Ali, C.; Docagne, F.; Plawinski, L.; MacKenzie, E. T.; Vivien, D.; Buisson, A. Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. J. Neurosci., 2001, 21, 3024-3033. PMID: 11312287.
    • (2001) J. Neurosci , vol.21 , pp. 3024-3033
    • Nicole, O.1    Ali, C.2    Docagne, F.3    Plawinski, L.4    McKenzie, E.T.5    Vivien, D.6    Buisson, A.7
  • 61
    • 0026651436 scopus 로고
    • Expression of Ciliary Neurotrophic Factor and the Neurotrophins-Nerve Growth Factor, Brain-Derived Neuro-trophic Factor and Neurotrophin 3-in Cultured Rat Hippocampal Astrocytes
    • Rudge, J. S.; Alderson, R. F.; Pasnikowski, E.; McClain, J.; Ip, N. Y.; Lindsay, R. M. Expression of Ciliary Neurotrophic Factor and the Neurotrophins-Nerve Growth Factor, Brain-Derived Neuro-trophic Factor and Neurotrophin 3-in Cultured Rat Hippocampal Astrocytes. Eur. J. Neurosci., 1992, 4, 459-471. DOI: 10. 1111/j. 1460-9568. 1992. tb00896. x.
    • (1992) Eur. J. Neurosci , vol.4 , pp. 459-471
    • Rudge, J.S.1    Alderson, R.F.2    Pasnikowski, E.3    McClain, J.4    Ip, N.Y.5    Lindsay, R.M.6
  • 62
    • 0035340452 scopus 로고    scopus 로고
    • Differential regulation of GDNF, neurturin, and their receptors in primary cultures of rat glial cells
    • Remy, S.; Naveilhan, P.; Brachet, P.; Neveu, I. Differential regulation of GDNF, neurturin, and their receptors in primary cultures of rat glial cells. J. Neurosci. Res., 2001, 64, 242-251. DOI: 10. 1002/jnr. 1072.
    • (2001) J. Neurosci. Res , vol.64 , pp. 242-251
    • Remy, S.1    Naveilhan, P.2    Brachet, P.3    Neveu, I.4
  • 63
    • 0029421101 scopus 로고
    • Neurotrophins and their trk receptors in cultured cells of the glial lineage and in white matter of the central nervous system
    • Condorelli, D. F.; Salin, T.; Dell', A. P.; Mudo, G.; Corsaro, M.; Timmusk, T.; Metsis, M.; Belluardo, N. Neurotrophins and their trk receptors in cultured cells of the glial lineage and in white matter of the central nervous system. J. Mol. Neurosci., 1995, 6, 237-248. DOI10. 1007/BF02736783.
    • (1995) J. Mol. Neurosci , vol.6 , pp. 237-248
    • Condorelli, D.F.1    Salin, T.2    Dell', A.P.3    Mudo, G.4    Corsaro, M.5    Timmusk, T.6    Metsis, M.7    Belluardo, N.8
  • 64
    • 27844498036 scopus 로고    scopus 로고
    • Muller Cells as a source of brain-derived neurotrophic factor in the retina: Noradrenaline upregulates brain-derived neurotrophic factor levels in cultured rat Muller cells
    • Seki, M.; Tanaka, T.; Sakai, Y.; Fukuchi, T.; Abe, H.; Nawa, H.; Takei N. Muller Cells as a source of brain-derived neurotrophic factor in the retina: noradrenaline upregulates brain-derived neurotrophic factor levels in cultured rat Muller cells. Neurochem. Res., 2005, 30, 1163-1170. DOI10. 1007/s11064-005-7936-7.
    • (2005) Neurochem. Res , vol.30 , pp. 1163-1170
    • Seki, M.1    Tanaka, T.2    Sakai, Y.3    Fukuchi, T.4    Abe, H.5    Nawa, H.6    Takei, N.7
  • 65
    • 2942511600 scopus 로고    scopus 로고
    • Increase by FK960, a novel cognitive enhancer, in glial cell line-derived neurotrophic factor production in cultured rat astrocytes
    • Koyama, Y.; Egawa, H.; Osakada, M.; Baba, A.; Matsuda, T. Increase by FK960, a novel cognitive enhancer, in glial cell line-derived neurotrophic factor production in cultured rat astrocytes. Biochem. Pharmacol., 2004, 68, 275-282. DOI: 10. 1016/j. bcp. 2004. 03. 023.
    • (2004) Biochem. Pharmacol , vol.68 , pp. 275-282
    • Koyama, Y.1    Egawa, H.2    Osakada, M.3    Baba, A.4    Matsuda, T.5
  • 66
    • 84870788182 scopus 로고    scopus 로고
    • Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: Differential regulation of FGF-2 by noradrenaline
    • Kajitani, N.; Hisaoka-Nakashima, K.; Morioka, N.; Okada-Tsuchioka, M.; Kaneko, M.; Kasai, M.; Shibasaki, C.; Nakata, Y.; Takebayashi, M. Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: differential regulation of FGF-2 by noradrenaline. PLoS. One., 2012, 7, e51197. doi: 10. 1371/journal. pone. 0051197.
    • (2012) PLoS. One , vol.7
    • Kajitani, N.1    Hisaoka-Nakashima, K.2    Morioka, N.3    Okada-Tsuchioka, M.4    Kaneko, M.5    Kasai, M.6    Shibasaki, C.7    Nakata, Y.8    Takebayashi, M.9
  • 67
    • 79952574434 scopus 로고    scopus 로고
    • Effects of dexmedetomidine on the release of glial cell line-derived neurotrophic factor from rat astrocyte cells
    • Yan, M.; Dai, H.; Ding, T.; Dai, A.; Zhang, F.; Yu, L.; Chen, G.; Chen, Z. Effects of dexmedetomidine on the release of glial cell line-derived neurotrophic factor from rat astrocyte cells. Neurochem. Int., 2011, 58, 549-557. DOI: 10. 1016/j. neuint. 2011. 01. 013.
    • (2011) Neurochem. Int , vol.58 , pp. 549-557
    • Yan, M.1    Dai, H.2    Ding, T.3    Dai, A.4    Zhang, F.5    Yu, L.6    Chen, G.7    Chen, Z.8
  • 68
    • 4143067835 scopus 로고    scopus 로고
    • Gene expression profiles of reactive astrocytes in dopamine-depleted striatum
    • Nakagawa, T. and Schwartz, J. P. Gene expression profiles of reactive astrocytes in dopamine-depleted striatum. Brain Pathol., 2004, 14, 275-280. DOI: 10. 1111/j. 1750-3639. 2004. tb00064. x.
    • (2004) Brain Pathol , vol.14 , pp. 275-280
    • Nakagawa, T.1    Schwartz, J.P.2
  • 69
    • 33747754751 scopus 로고    scopus 로고
    • Monoaminergic neuronal activity up-regulates BDNF synthesis in cultured neonatal rat astrocytes
    • Juric, D. M.; Miklic, S.; Carman-Krzan, M. Monoaminergic neuronal activity up-regulates BDNF synthesis in cultured neonatal rat astrocytes. Brain Res., 2006, 1108, 54-62. DOI: 10. 1016/j. brainres. 2006. 06. 008.
    • (2006) Brain Res , vol.1108 , pp. 54-62
    • Juric, D.M.1    Miklic, S.2    Carman-Krzan, M.3
  • 70
    • 74449085179 scopus 로고    scopus 로고
    • Regulatory role of monoamine neurotransmitters in astrocytic NT-3 synthesis
    • Mele, T.; Carman-Krzan, M.; Juric, D. M. Regulatory role of monoamine neurotransmitters in astrocytic NT-3 synthesis. Int. J. Dev. Neurosci., 2010, 28, 13-19. DOI: 10. 1016/j. ijdevneu. 2009. 10. 003.
    • (2010) Int. J. Dev. Neurosci , vol.28 , pp. 13-19
    • Mele, T.1    Carman-Krzan, M.2    Juric, D.M.3
  • 71
    • 0019353236 scopus 로고
    • Cell loss in the locus coeruleus in senile dementia of Alzheimer type
    • Tomlinson, B. E.; Irving D.; Blessed G. Cell loss in the locus coeruleus in senile dementia of Alzheimer type. J. Neurol. Sci., 1981, 49, 419-428. DOI: 10. 1016/0022-510X(81)90031-9.
    • (1981) J. Neurol. Sci , vol.49 , pp. 419-428
    • Tomlinson, B.E.1    Irving, D.2    Blessed, G.3
  • 73
    • 0018305844 scopus 로고
    • Changes in the brain catecholamines in patients with dementia of Alzheimer type
    • Adolfsson, R.; Gottfries, C. G.; Roos, B. E.; Winblad, B. Changes in the brain catecholamines in patients with dementia of Alzheimer type. Br. J. Psychiatry, 1979, 135, 216-223. doi: 10. 1192/bjp. 135. 3. 216.
    • (1979) Br. J. Psychiatry , vol.135 , pp. 216-223
    • Adolfsson, R.1    Gottfries, C.G.2    Roos, B.E.3    Winblad, B.4
  • 74
    • 0018857625 scopus 로고
    • Changes in the monoamine containing neurones of the human CNS in senile dementia
    • Mann, D. M.; Lincoln, J.; Yates, P. O.; Stamp, J. E.; Toper, S. Changes in the monoamine containing neurones of the human CNS in senile dementia. Br. J. Psychiatry, 1980, 136, 533-541. doi: 10. 1192/bjp. 136. 6. 533.
    • (1980) Br. J. Psychiatry , vol.136 , pp. 533-541
    • Mann, D.M.1    Lincoln, J.2    Yates, P.O.3    Stamp, J.E.4    Toper, S.5
  • 75
    • 33846583006 scopus 로고    scopus 로고
    • Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease
    • Grudzien, A.; Shaw, P.; Weintraub, S.; Bigio, E.; Mash, D. C.; Mesulam, M. M. Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease. Neurobiol. Aging, 2006, 28, 327-35. DOI: 10. 1016/j. neurobiolaging. 2006. 02. 007.
    • (2006) Neurobiol. Aging , vol.28 , pp. 327-335
    • Grudzien, A.1    Shaw, P.2    Weintraub, S.3    Bigio, E.4    Mash, D.C.5    Mesulam, M.M.6
  • 76
    • 33846583006 scopus 로고    scopus 로고
    • Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease
    • Grudzien, A.; Shaw, P.; Weintraub, S.; Bigio, E.; Mash, D. C.; Mesulam, M. M. Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease. Neurobiol. Aging, 2007, 28, 327-335. DOI: 10. 1016/j. neurobiolaging. 2006. 02. 007.
    • (2007) Neurobiol. Aging , vol.28 , pp. 327-335
    • Grudzien, A.1    Shaw, P.2    Weintraub, S.3    Bigio, E.4    Mash, D.C.5    Mesulam, M.M.6
  • 77
    • 0037337815 scopus 로고    scopus 로고
    • Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
    • Zarow, C.; Lyness, S. A.; Mortimer, J. A.; Chui, H. C. Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch. Neurol., 2003, 60, 337-341. doi: 10. 1001/archneur. 60. 3. 337.
    • (2003) Arch. Neurol , vol.60 , pp. 337-341
    • Zarow, C.1    Lyness, S.A.2    Mortimer, J.A.3    Chui, H.C.4
  • 78
    • 0024820792 scopus 로고
    • Is Alzheimer's disease an anterograde degeneration, originating in the brainstem, and disrupting metabolic and functional interactions between neurons and glial cells?
    • Hertz L. Is Alzheimer's disease an anterograde degeneration, originating in the brainstem, and disrupting metabolic and functional interactions between neurons and glial cells? Brain Res. Brain Res. Rev., 1989, 14, 335-353. DOI: 10. 1016/0165-0173(89)90017-9.
    • (1989) Brain Res. Brain Res. Rev , vol.14 , pp. 335-353
    • Hertz, L.1
  • 80
    • 0025789565 scopus 로고
    • Selective effects of DSP-4 on locus coeruleus axons: Are there pharmacologically different types of noradrenergic axons in the central nervous system?
    • Fritschy, J. M. and Grzanna, R. Selective effects of DSP-4 on locus coeruleus axons: are there pharmacologically different types of noradrenergic axons in the central nervous system? Prog. Brain Res., 1991, 88, 257-268. DOI: 10. 1016/S0079-6123(08)63815-7.
    • (1991) Prog. Brain Res , vol.88 , pp. 257-268
    • Fritschy, J.M.1    Grzanna, R.2
  • 82
    • 34249281253 scopus 로고    scopus 로고
    • Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease
    • Kalinin S.; Gavrilyuk V.; Polak P. E.; Heneka M. T.; Feinstein D. L. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol. Aging, 2006. DOI: 10. 1016/j. neurobiolaging. 2006. 06. 003.
    • (2006) Neurobiol. Aging
    • Kalinin, S.1    Gavrilyuk, V.2    Polak, P.E.3    Heneka, M.T.4    Feinstein, D.L.5
  • 83
    • 33847782486 scopus 로고    scopus 로고
    • Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes
    • PMID: 17324270
    • Pugh, P. L.; Vidgeon-Hart, M. P.; Ashmeade, T.; Culbert, A. A.; Seymour, Z.; Perren M. J.; Joyce, F.; Bate, S. T.; Babin, A.; Virley D. J.; Richardson, J. C.; Upton, N.; Sunter, D. Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes. J. Neuroinflammation., 2007, 4, 8. PMID: 17324270.
    • (2007) J. Neuroinflammation , vol.4 , pp. 8
    • Pugh, P.L.1    Vidgeon-Hart, M.P.2    Ashmeade, T.3    Culbert, A.A.4    Seymour, Z.5    Perren, M.J.6    Joyce, F.7    Bate, S.T.8    Babin, A.9    Virley, D.J.10    Richardson, J.C.11    Upton, N.12    Sunter, D.13
  • 86
    • 34249281253 scopus 로고    scopus 로고
    • Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease
    • Kalinin, S.; Gavrilyuk, V.; Polak, P. E.; Vasser, R.; Zhao, J.; Heneka M. T.; Feinstein, D. L. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol. Aging, 2007, 28, 1206-1214. DOI: 10. 1016/j. neurobiolaging. 2006. 06. 003.
    • (2007) Neurobiol. Aging , vol.28 , pp. 1206-1214
    • Kalinin, S.1    Gavrilyuk, V.2    Polak, P.E.3    Vasser, R.4    Zhao, J.5    Heneka, M.T.6    Feinstein, D.L.7
  • 87
    • 77956225289 scopus 로고    scopus 로고
    • Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits
    • Jardanhazi-Kurutz, D.; Kummer, M. P.; Terwel, D.; Vogel, K.; Dyrks T.; Thiele, A.; Heneka, M. T. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochem. Int., 2010. DOI: 10. 1016/j. neuint. 2010. 02. 001.
    • (2010) Neurochem. Int
    • Jardanhazi-Kurutz, D.1    Kummer, M.P.2    Terwel, D.3    Vogel, K.4    Dyrks, T.5    Thiele, A.6    Heneka, M.T.7
  • 89
    • 57749114849 scopus 로고    scopus 로고
    • Early locus coeruleus degeneration and olfactory dysfunctions in Tg2576 mice
    • Guerin, D.; Sacquet, J.; Mandairon N.; Jourdan F.; Didier A. Early locus coeruleus degeneration and olfactory dysfunctions in Tg2576 mice. Neurobiol. Aging, 2007. DOI: 10. 1016/j. neurobiolaging. 2007. 05. 020.
    • (2007) Neurobiol. Aging
    • Guerin, D.1    Sacquet, J.2    Mandairon, N.3    Jourdan, F.4    Didier, A.5
  • 90
    • 81555214518 scopus 로고    scopus 로고
    • A comparative study of five mouse models of Alzheimer's disease: Cell cycle events reveal new insights into neurons at risk for death
    • Li L.; Cheung T.; Chen J.; Herrup K. A comparative study of five mouse models of Alzheimer's disease: cell cycle events reveal new insights into neurons at risk for death. Int. J. Alzheimers. Dis., 2011, 2011, 171464. http://dx. doi. org/10. 4061/2011/171464.
    • (2011) Int. J. Alzheimers. Dis , vol.2011
    • Li, L.1    Cheung, T.2    Chen, J.3    Herrup, K.4
  • 91
    • 84870004031 scopus 로고    scopus 로고
    • Where, when, and in what form does sporadic Alzheimer's disease begin?
    • Braak, H. and Del, T. K. Where, when, and in what form does sporadic Alzheimer's disease begin? Curr. Opin. Neurol., 2012, 25, 708-714. doi: 10. 1097/WCO. 0b013e32835a3432.
    • (2012) Curr. Opin. Neurol , vol.25 , pp. 708-714
    • Braak, H.1    Del, T.K.2
  • 92
    • 84864384240 scopus 로고    scopus 로고
    • The relationship between subcortical tau pathology and Alzheimer's disease
    • Attems, J.; Thal, D. R.; Jellinger, K. A. The relationship between subcortical tau pathology and Alzheimer's disease. Biochem. Soc. Trans., 2012, 40, 711-715. doi: 10. 1042/BST20120034.
    • (2012) Biochem. Soc. Trans , vol.40 , pp. 711-715
    • Attems, J.1    Thal, D.R.2    Jellinger, K.A.3
  • 93
    • 0028039812 scopus 로고
    • Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo
    • Arenas, E. and Persson, H. Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo. Nature, 1994, 367, 368-371. doi: 10. 1038/367368a0.
    • (1994) Nature , vol.367 , pp. 368-371
    • Arenas, E.1    Persson, H.2
  • 94
    • 0041976009 scopus 로고    scopus 로고
    • Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons
    • Holm, P. C.; Rodriguez, F. J.; Kresse, A.; Canals, J. M.; Silos-Santiago I.; Arenas, E. Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Development, 2003, 130, 3535-3545. doi: 10. 1242/dev. 00565.
    • (2003) Development , vol.130 , pp. 3535-3545
    • Holm, P.C.1    Rodriguez, F.J.2    Kresse, A.3    Canals, J.M.4    Silos-Santiago, I.5    Arenas, E.6
  • 95
    • 77950652321 scopus 로고    scopus 로고
    • Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity
    • Counts, S. E. and Mufson, E. J. Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity. J. Neurochem., 2010. DOI: 10. 1111/j. 1471-4159. 2010. 06622. x.
    • (2010) J. Neurochem
    • Counts, S.E.1    Mufson, E.J.2
  • 96
    • 34347384600 scopus 로고    scopus 로고
    • Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice
    • Luellen, B. A.; Bianco, L. E.; Schneider, L. M.; Andrews, A. M. Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice. Genes Brain Behav., 2007, 6, 482-490. DOI: 10. 1111/j. 1601-183X. 2006. 00279. x.
    • (2007) Genes Brain Behav , vol.6 , pp. 482-490
    • Luellen, B.A.1    Bianco, L.E.2    Schneider, L.M.3    Andrews, A.M.4
  • 97
    • 1242338805 scopus 로고    scopus 로고
    • BDNF is necessary for maintenance of noradrenergic innervations in the aged rat brain
    • Matsunaga, W.; Shirokawa, T.; Isobe, K. BDNF is necessary for maintenance of noradrenergic innervations in the aged rat brain. Neurobiol Aging, 2004, 25, 341-348. DOI: 10. 1016/S0197-4580(03)00093-9.
    • (2004) Neurobiol Aging , vol.25 , pp. 341-348
    • Matsunaga, W.1    Shirokawa, T.2    Isobe, K.3
  • 98
    • 33244492856 scopus 로고    scopus 로고
    • Effects of BDNF infusion on the axon terminals of locus coeruleus neurons of aging rats
    • Nakai S.; Matsunaga W.; Ishida Y.; Isobe K.; Shirokawa T. Effects of BDNF infusion on the axon terminals of locus coeruleus neurons of aging rats. Neurosci. Res., 2006, 54, 213-219. DOI: 10. 1016/j. neures. 2005. 12. 001.
    • (2006) Neurosci. Res , vol.54 , pp. 213-219
    • Nakai, S.1    Matsunaga, W.2    Ishida, Y.3    Isobe, K.4    Shirokawa, T.5
  • 99
    • 0031889870 scopus 로고    scopus 로고
    • Distribution of the neurotrophins brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the postnatal rat brain: An immuno-cytochemical study
    • Friedman, W. J.; Black, I. B.; Kaplan, D. R. Distribution of the neurotrophins brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the postnatal rat brain: an immuno-cytochemical study. Neuroscience, 1998, 84, 101-114. DOI: 10. 1016/S0306-4522(97)00526-5.
    • (1998) Neuroscience , vol.84 , pp. 101-114
    • Friedman, W.J.1    Black, I.B.2    Kaplan, D.R.3
  • 100
    • 33744785082 scopus 로고    scopus 로고
    • The norepinephrine level is decreased in the lymphocytes of long-term interferon-beta-treated multiple sclerosis patients
    • Rajda, C.; Bencsik, K.; Fuvesi, J.; Seres, E.; Vecsei, L.; Bergquist, J. The norepinephrine level is decreased in the lymphocytes of long-term interferon-beta-treated multiple sclerosis patients. Mult. Scler., 2006, 12, 265-270. doi: 10. 1191/135248506ms1269oa.
    • (2006) Mult. Scler , vol.12 , pp. 265-270
    • Rajda, C.1    Bencsik, K.2    Fuvesi, J.3    Seres, E.4    Vecsei, L.5    Bergquist, J.6
  • 101
    • 0036890452 scopus 로고    scopus 로고
    • Catecholamine production and tyrosine hydroxylase expression in peripheral blood mononuclear cells from multiple sclerosis patients: Effect of cell stimulation and possible relevance for activation-induced apoptosis
    • Cosentino M.; Zaffaroni M.; Marino F.; Bombelli R.; Ferrari M.; Rasini E.; Lecchini S.; Ghezzi A.; Frigo G. Catecholamine production and tyrosine hydroxylase expression in peripheral blood mononuclear cells from multiple sclerosis patients: effect of cell stimulation and possible relevance for activation-induced apoptosis. J. Neuroimmunol., 2002, 133, 233-240. DOI: 10. 1016/S0165-5728(02)00372-7.
    • (2002) J. Neuroimmunol , vol.133 , pp. 233-240
    • Cosentino, M.1    Zaffaroni, M.2    Marino, F.3    Bombelli, R.4    Ferrari, M.5    Rasini, E.6    Lecchini, S.7    Ghezzi, A.8    Frigo, G.9
  • 102
    • 0026728944 scopus 로고
    • Beta-Adrenergic receptor density and function of peripheral blood mononuclear cells are increased in multiple sclerosis: A regulatory role for cortisol and interleukin-1
    • PMID: 1325138
    • Zoukos, Y.; Leonard, J. P.; Thomaides, T.; Thompson, A. J.; Cuzner, M. L. beta-Adrenergic receptor density and function of peripheral blood mononuclear cells are increased in multiple sclerosis: a regulatory role for cortisol and interleukin-1. Ann. Neurol., 1992, 31, 657-662. PMID: 1325138.
    • (1992) Ann. Neurol , vol.31 , pp. 657-662
    • Zoukos, Y.1    Leonard, J.P.2    Thomaides, T.3    Thompson, A.J.4    Cuzner, M.L.5
  • 103
    • 0023872336 scopus 로고
    • Chemical sympathectomy augments the severity of experimental allergic encephalomyelitis
    • Chelmicka-Schorr, E.; Checinski, M.; Arnason, B. G. Chemical sympathectomy augments the severity of experimental allergic encephalomyelitis. J. Neuroimmunol., 1988, 17, 347-350. DOI: 10. 1016/0165-5728(88)90125-7.
    • (1988) J. Neuroimmunol , vol.17 , pp. 347-350
    • Chelmicka-Schorr, E.1    Checinski, M.2    Arnason, B.G.3
  • 104
    • 0026345308 scopus 로고
    • Hypothalamic noradrenergic pathways exert an influence on neuroendocrine and clinical status in experimental autoimmune encephalomyelitis
    • Leonard, J. P.; MacKenzie, F. J.; Patel, H. A.; Cuzner, M. L. Hypothalamic noradrenergic pathways exert an influence on neuroendocrine and clinical status in experimental autoimmune encephalomyelitis. Brain Behav. Immun., 1991, 5, 328-338. DOI: 10. 1016/0889-1591(91)90028-9.
    • (1991) Brain Behav. Immun , vol.5 , pp. 328-338
    • Leonard, J.P.1    McKenzie, F.J.2    Patel, H.A.3    Cuzner, M.L.4
  • 105
    • 0027395328 scopus 로고
    • The beta 2-adrenergic agonist terbutaline suppresses acute passive transfer experimental autoimmune myasthenia gravis (EAMG)
    • Chelmicka-Schorr, E.; Wollmann, R. L.; Kwasniewski, M. N.; Kim, D. H.; Dupont, B. L. The beta 2-adrenergic agonist terbutaline suppresses acute passive transfer experimental autoimmune myasthenia gravis (EAMG). Int. J. Immunopharmacol., 1993, 15, 19-24. DOI: 10. 1016/0192-0561(93)90027-V.
    • (1993) Int. J. Immunopharmacol , vol.15 , pp. 19-24
    • Chelmicka-Schorr, E.1    Wollmann, R.L.2    Kwasniewski, M.N.3    Kim, D.H.4    Dupont, B.L.5
  • 106
    • 0028983525 scopus 로고
    • Beta-adrenergic agonists suppress chronic/relapsing experimental allergic encephalomyelitis (CREAE) in Lewis rats
    • Wiegmann, K.; Muthyala, S.; Kim, D. H.; Arnason, B. G.; Chelmicka-Schorr E. Beta-adrenergic agonists suppress chronic/relapsing experimental allergic encephalomyelitis (CREAE) in Lewis rats. J. Neuroimmunol., 1995, 56, 201-206. DOI: 10. 1016/0165-5728(94)00153-F.
    • (1995) J. Neuroimmunol , vol.56 , pp. 201-206
    • Wiegmann, K.1    Muthyala, S.2    Kim, D.H.3    Arnason, B.G.4    Chelmicka-Schorr, E.5
  • 107
    • 0016512884 scopus 로고
    • Change in monoamine content and monoamine oxidase activity in brain structures during experimental allergic encephalomyelitis
    • PMID: 1222257
    • Khoruzhaia, T. A. and Saakov, B. A. [Change in monoamine content and monoamine oxidase activity in brain structures during experimental allergic encephalomyelitis]. Biull. Eksp. Biol. Med., 1975, 79, 80-82. PMID: 1222257.
    • (1975) Biull. Eksp. Biol. Med , vol.79 , pp. 80-82
    • Khoruzhaia, T.A.1    Saakov, B.A.2
  • 108
    • 0022539731 scopus 로고
    • Changes of neurotransmitter systems in chronic relapsing experimental allergic encephalomyelitis in rat brain and spinal cord
    • Krenger W.; Honegger C. G.; Feurer C.; Cammisuli S. Changes of neurotransmitter systems in chronic relapsing experimental allergic encephalomyelitis in rat brain and spinal cord. J. Neurochem., 1986, 47, 1247-1254. DOI: 10. 1111/j. 1471-4159. 1986. tb00747. x.
    • (1986) J. Neurochem , vol.47 , pp. 1247-1254
    • Krenger, W.1    Honegger, C.G.2    Feurer, C.3    Cammisuli, S.4
  • 109
    • 0020626598 scopus 로고
    • Norepinephrine depletion in the spinal cord gray matter of rats with experimental allergic encephalomyelitis
    • White, S. R.; Bhatnagar, R. K.; Bardo, M. T. Norepinephrine depletion in the spinal cord gray matter of rats with experimental allergic encephalomyelitis. J. Neurochem., 1983, 40, 1771-1773. DOI: 10. 1111/j. 1471-4159. 1983. tb08156. x.
    • (1983) J. Neurochem , vol.40 , pp. 1771-1773
    • White, S.R.1    Bhatnagar, R.K.2    Bardo, M.T.3
  • 111
    • 0034725454 scopus 로고    scopus 로고
    • [3H]dihydroalprenolol binding to beta adrenergic receptors in multiple sclerosis brain
    • Zeinstra, E.; Wilczak, N.; De Keyser, J. [3H]dihydroalprenolol binding to beta adrenergic receptors in multiple sclerosis brain. Neurosci. Lett., 2000, 289, 75-77. DOI: 10. 1016/S0304-3940(00) 01254-4.
    • (2000) Neurosci. Lett , vol.289 , pp. 75-77
    • Zeinstra, E.1    Wilczak, N.2    De Keyser, J.3
  • 112
    • 79952147737 scopus 로고    scopus 로고
    • Locus coeruleus damage and noradrenaline reductions in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Polak P. E.; Kalinin S.; Feinstein D. L. Locus coeruleus damage and noradrenaline reductions in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain, 2011, 134, 665-677. doi: 10. 1093/brain/awq362.
    • (2011) Brain , vol.134 , pp. 665-677
    • Polak, P.E.1    Kalinin, S.2    Feinstein, D.L.3
  • 113
    • 0027549290 scopus 로고
    • Locus ceruleus and immunity. II. Suppression of experimental allergic encephalomyelitis and hypersensitivity skin reactions in rats with lesioned locus ceruleus
    • Jovanova-Nesic, K.; Nikolic, V.; Jankovic, B. D. Locus ceruleus and immunity. II. Suppression of experimental allergic encephalomyelitis and hypersensitivity skin reactions in rats with lesioned locus ceruleus. Int. J. Neurosci., 1993, 68, 289-294. DOI: 10. 3109/00207459308994284.
    • (1993) Int. J. Neurosci , vol.68 , pp. 289-294
    • Jovanova-Nesic, K.1    Nikolic, V.2    Jankovic, B.D.3
  • 114
    • 67649221284 scopus 로고    scopus 로고
    • The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines
    • Vollmar P.; Nessler S.; Kalluri S. R.; Hartung H. P.; Hemmer B. The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines. Int. J. Neuropsychopharmacol., 2008, 1-12. http://dx. doi. org/10. 1017/S1461145708009425.
    • (2008) Int. J. Neuropsychopharmacol , pp. 1-12
    • Vollmar, P.1    Nessler, S.2    Kalluri, S.R.3    Hartung, H.P.4    Hemmer, B.5
  • 115
    • 60549097585 scopus 로고    scopus 로고
    • Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis
    • Paintlia A. S.; Paintlia M. K.; Singh I.; Skoff R. B.; Singh A. K. Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis. Glia, 2008, 57, 182-93. DOI: 10. 1002/glia. 20745.
    • (2008) Glia , vol.57 , pp. 182-193
    • Paintlia, A.S.1    Paintlia, M.K.2    Singh, I.3    Skoff, R.B.4    Singh, A.K.5
  • 116
    • 0023804163 scopus 로고
    • Long-term effects of RU24722 on tyrosine hydroxylase of the rat brain
    • Labatut, R.; Richard, F.; Milne, B.; Quintin, L.; Lecestre, D.; Pujol, J. F. Long-term effects of RU24722 on tyrosine hydroxylase of the rat brain. J. Neurochem., 1988, 51, 1367-1374. DOI: 10. 1111/j. 1471-4159. 1988. tb01099. x.
    • (1988) J. Neurochem , vol.51 , pp. 1367-1374
    • Labatut, R.1    Richard, F.2    Milne, B.3    Quintin, L.4    Lecestre, D.5    Pujol, J.F.6
  • 117
    • 0025124746 scopus 로고
    • Ontogeny of tyrosine hydroxylase concentration in locus coeruleus of newborn rats: Long-term effects of RU24722
    • Zyzek, E.; Richard, F.; Bouilloux, J. P.; Pujol, J. F. Ontogeny of tyrosine hydroxylase concentration in locus coeruleus of newborn rats: long-term effects of RU24722. J. Neurochem., 1990, 55, 849-853. DOI: 10. 1111/j. 1471-4159. 1990. tb04569. x.
    • (1990) J. Neurochem , vol.55 , pp. 849-853
    • Zyzek, E.1    Richard, F.2    Bouilloux, J.P.3    Pujol, J.F.4
  • 118
    • 0029900183 scopus 로고    scopus 로고
    • Tyrosine hydroxylase expression within Balb/C and C57black/6 mouse locus coeruleus. II. Quantitative study of the enzyme level
    • Ginovart, N.; Marcel, D.; Bezin, L.; Gagne, C.; Pujol, J. F.; Weissmann D. Tyrosine hydroxylase expression within Balb/C and C57black/6 mouse locus coeruleus. II. Quantitative study of the enzyme level. Brain Res., 1996, 719, 45-55. DOI: 10. 1016/0006-8993(96)00075-3.
    • (1996) Brain Res , vol.719 , pp. 45-55
    • Ginovart, N.1    Marcel, D.2    Bezin, L.3    Gagne, C.4    Pujol, J.F.5    Weissmann, D.6
  • 119
    • 0034728660 scopus 로고    scopus 로고
    • Singular subsets of locus coeruleus neurons may recover tyrosine hydroxylase phenotype transiently expressed during development
    • Bezin, L.; Marcel, D.; Desgeorges, S.; Pujol, J. F.; Weissmann, D. Singular subsets of locus coeruleus neurons may recover tyrosine hydroxylase phenotype transiently expressed during development. Brain Res. Mol. Brain Res., 2000, 76, 275-281. DOI: 10. 1016/S0169-328X(00)00007-3.
    • (2000) Brain Res. Mol. Brain Res , vol.76 , pp. 275-281
    • Bezin, L.1    Marcel, D.2    Desgeorges, S.3    Pujol, J.F.4    Weissmann, D.5
  • 120
    • 84862823188 scopus 로고    scopus 로고
    • The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: Effects on the Locus coeruleus
    • Polak, P. E.; Kalinin, S.; Braun, D.; Sharp, A.; Lin S. X.; Feinstein, D. L. The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus. J. Neurochem., 2012, 121, 206-216. DOI: 10. 1111/j. 1471-4159. 2012. 07673. x.
    • (2012) J. Neurochem , vol.121 , pp. 206-216
    • Polak, P.E.1    Kalinin, S.2    Braun, D.3    Sharp, A.4    Lin, S.X.5    Feinstein, D.L.6
  • 121
    • 84900326653 scopus 로고    scopus 로고
    • Trauma exposure and sleep: Using a rodent model to understand sleep function in PTSD
    • Vanderheyden, W. M.; Poe, G. R.; Liberzon, I. Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD. Exp. Brain Res., 2014, 232, 1575-1584. DOI: 10. 1007/s00221-014-3890-4.
    • (2014) Exp. Brain Res , vol.232 , pp. 1575-1584
    • Vanderheyden, W.M.1    Poe, G.R.2    Liberzon, I.3
  • 122
    • 84888039502 scopus 로고    scopus 로고
    • Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus
    • Pietrzak, R. H.; Gallezot, J. D.; Ding, Y. S.; Henry, S.; Potenza, M. N.; Southwick, S. M.; Krystal, J. H.; Carson, R. E.; Neumeister, A. Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus. JAMA Psychiatry, 2013, 70, 1199-1205. doi: 10. 1001/jamapsychiatry. 2013. 399.
    • (2013) JAMA Psychiatry , vol.70 , pp. 1199-1205
    • Pietrzak, R.H.1    Gallezot, J.D.2    Ding, Y.S.3    Henry, S.4    Potenza, M.N.5    Southwick, S.M.6    Krystal, J.H.7    Carson, R.E.8    Neumeister, A.9
  • 124
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
    • Oakley, H.; Cole, S. L.; Logan, S.; Maus, E.; Shao, P.; Craft, J.; Guillozet-Bongaarts, A.; Ohno, M.; Disterhoft, J.; Van, E. L.; Berry, R.; Vassar, R. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci., 2006, 26, 10129-10140. doi: 10. 1523/JNEUROSCI. 1202-06. 2006.
    • (2006) J. Neurosci , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van, E.L.10    Berry, R.11    Vassar, R.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.