Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1β-induced neurotoxicity

European Journal of Pharmacology

Volumn 626, Issue 2-3, 2010, Pages 219-228

  McNamee, Eoin N ^a   Ryan, Karen M ^a   Kilroy, Dana ^a   Connor, Thomas J ^a  

^a Trinity Biomedical Sciences Institute   (Ireland)

Author keywords

adrenoceptor; Glial cell; IL 1 ; IL 1ra; IL 1RII; Neuroprotection; Noradrenaline

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; NORADRENALIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GLIA CELL; MICROGLIA; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MICROGLIA; NEUROGLIA; NEURONS; NOREPINEPHRINE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, INTERLEUKIN-1 TYPE II; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 70849110410     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.054     Document Type: Article

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