Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A

FEBS Letters

Volumn 588, Issue 23, 2014, Pages 4487-4496

  Stanger, Karen ^a   Maurer, Till ^a   Kaluarachchi, Harini ^a   Coons, Mary ^a   Franke, Yvonne ^a   Hannoush, Rami N ^a  

^a GENENTECH INC   (United States)

Author keywords

Cyclotide; Cystine knot peptide; MCoTI II; Recombinant expression; Sortase Protein engineering

Indexed keywords

AMIDE; CYCLOTIDE; CYCLOTIDE MCOTI II; PEPTIDE; RECOMBINANT CYSTINE KNOT PEPTIDE; SORTASE; SORTASE A; UNCLASSIFIED DRUG; AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; CYCLOPEPTIDE; CYSTEINE PROTEINASE; CYSTINE; RECOMBINANT PROTEIN;

ARTICLE; BIOMIMETICS; BIOSYNTHESIS; CATALYSIS; CYCLIZATION; ENZYME ACTIVITY; ENZYME ENGINEERING; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; CYCLIZATION; CYSTEINE ENDOPEPTIDASES; CYSTINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS;

EID: 84910617831     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.10.020     Document Type: Article

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