In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide

Journal of the American Chemical Society

Volumn 135, Issue 31, 2013, Pages 11623-11633

  Ji, Yanbin ^a   Majumder, Subhabrata ^b   Millard, Melissa ^a   Borra, Radhika ^a   Bi, Tao ^a   Elnagar, Ahmed Y ^a   Neamati, Nouri ^a   Shekhtman, Alexander ^b   Camarero, Julio A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL LINES; LINEAR PEPTIDES; NANOMOLAR AFFINITY; OVER-EXPRESSION; PROTEIN-PROTEIN INTERACTIONS; THERAPEUTIC STRATEGY; THERAPEUTIC USE; TUMOR SUPPRESSORS;

BIOCHEMISTRY; CELL CULTURE; CHEMICAL ACTIVATION; PEPTIDES; TUMORS;

SCAFFOLDS (BIOLOGY);

ANTINEOPLASTIC AGENT; CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLOTIDE; MCO PMI; NUTLIN 3; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOAVAILABILITY; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; CHEMICAL ENGINEERING; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFECT; FEMALE; IN VIVO STUDY; MOUSE; NEOPLASM; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SERUM; UPREGULATION; WILD TYPE;

EID: 84881250938     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja405108p     Document Type: Article

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