Hypoxic trophoblast HMGB1 induces endothelial cell hyperpermeability via the trl-4/caveolin-1 pathway

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 5000-5012

  Jiang, Rongzhen ^a   Cai, Jingjing ^b   Zhu, Zhaowei ^c   Chen, Dandan ^b   Wang, Jiemei ^b   Wang, Qingde ^b   Teng, Yincheng ^a   Huang, Yajuan ^a   Tao, Minfang ^a   Xia, Aibin ^b   Xue, Min ^b   Zhou, Shenghua ^c   Chen, Alex F ^b  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^b THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; GLYCYRRHIZIC ACID; HIGH MOBILITY GROUP B1 PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; CAV1 PROTEIN, MOUSE; CULTURE MEDIUM; HMGB1 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL HYPOXIA; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; EDEMA; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOLAYER CULTURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; TROPHOBLAST; WESTERN BLOTTING; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHARMACOLOGY; PREGNANCY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANOXIA; CAVEOLIN 1; CELL LINE; CELL MEMBRANE PERMEABILITY; CULTURE MEDIA, CONDITIONED; FEMALE; GENE EXPRESSION REGULATION; GLYCYRRHIZIC ACID; HMGB1 PROTEIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PREGNANCY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TROPHOBLASTS;

EID: 84910110997     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1303445     Document Type: Article

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