Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

Nature Communications

Volumn 3, Issue , 2012, Pages

  Orsenigo, Fabrizio ^a   Giampietro, Costanza ^a   Ferrari, Aldo ^b   Corada, Monica ^a   Galaup, Ariane ^c   Sigismund, Sara ^a   Ristagno, Giuseppe ^d   Maddaluno, Luigi ^a   Koh, Gou Young ^e   Franco, Davide ^b   Kurtcuoglu, Vartan ^b,f   Poulikakos, Dimos ^b   Baluk, Peter ^g   McDonald, Donald ^g   Grazia Lampugnani, Maria ^d   Dejana, Elisabetta ^a,h  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b ETH ZURICH   (Switzerland)

^c INSERM   (France)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^e Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^f UNIVERSITY OF ZURICH   (Switzerland)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; HISTAMINE; VASCULAR ENDOTHELIAL CADHERIN;

PERMEABILITY;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL JUNCTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; POINT MUTATION; PROTEIN PHOSPHORYLATION; SHEAR STRESS; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY SPECIFICITY; ANTIGENS, CD; ARTERIES; BRADYKININ; CADHERINS; CAPILLARY PERMEABILITY; ENDOCYTOSIS; ENZYME ACTIVATION; HEMODYNAMICS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; SRC-FAMILY KINASES; STRESS, MECHANICAL; UBIQUITINATION; VEINS;

EID: 84870688010     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2199     Document Type: Article

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