Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis

Arthritis and Rheumatism

Volumn 58, Issue 9, 2008, Pages 2675-2685

  Hamada, Takashi ^a   Torikai, Motofumi ^a   Kuwazuru, Ai ^a,b   Tanaka, Motoyuki ^a   Horai, Naoto ^a,b   Fukuda, Takeshi ^b   Yamada, Shingo ^c   Nagayama, Shinichi ^a,b   Hashiguchi, Kanehisa ^d   Sunahara, Nobuhiko ^e   Fukuzaki, Koichiro ^b   Nagata, Ryoichi ^b   Komiya, Setsuro ^a   Maruyama, Ikuro ^a   Fukuda, Takeo ^a   Abeyama, Kazuhiro ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^c SHINO TEST CORPORATION   (Japan)

^d Hashiguchi Orthopaedic Surgery Clinic   (Japan)

^e Kagoshima Red Cross Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LACTIC ACID; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTHRITIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; COUPLING FACTOR; EXTRACELLULAR SPACE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXEMIA; INFLAMMATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PSEUDOGOUT; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; TISSUE DISTRIBUTION;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANOXIA; ARTHRITIS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HMGB1 PROTEIN; HUMANS; INFLAMMATION; INTERLEUKIN-1; JOINTS; L-LACTATE DEHYDROGENASE; LACTIC ACID; MALE; MICE; MIDDLE AGED; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 51849133187     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23729     Document Type: Article

References (46)

1. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002;418:191-5.
2. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999;285:248-51.
3. Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, et al. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 2003;48:971-81.
4. Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, et al. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel anti-inflammatory mechanism. J Clin Invest 2005;115:1267-74.
5. Pullerits R, Jonsson IM, Verdrengh M, Bokarewa M, Andersson U, Erlandsson-Harris H, et al. High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis. Arthritis Rheum 2003;48:1693-700.
6. Kokkola R, Sundberg E, Ulfgren AK, Palmblad K, Li J, Wang H, et al. High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. Arthritis Rheum 2002;46:2598-603.
7. Kokkola R, Li J, Sundberg E, Aveberger AC, Palmblad K, Yang H, et al. Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum 2003;48:2052-8.
8. Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, Shelhamer JH, et al. Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 2003;101:2652-60.
9. Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000;192:565-70.
10. Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, et al. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol 2005;61:1-9.
11. Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001;108:949-55.
12. Abeyama K, Eng W, Jester JV, Vink AA, Edelbaum D, Cockerell CJ, et al. A role for NF-κB-dependent gene transactivation in sunburn. J Clin Invest 2000;105:1751-9.
13. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J Clin Invest 1998;101:890-8.
14. Gallucci S, Lolkema M, Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat Med 1999;5:1249-55.
15. Brenchley PE. Angiogenesis in inflammatory joint disease: a target for therapeutic intervention. Clin Exp Immunol 2000;121:426-9.
16. Peters CL, Morris CJ, Mapp PI, Blake DR, Lewis CE, Winrow VR. The transcription factors hypoxia-inducible factor 1α and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis. Arthritis Rheum 2004;50:291-6.
17. Holmdahl R, Jansson L, Andersson M, Larsson E. Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis. Immunology 1988;65:305-10.
18. Ahmed M, Bjurholm A, Schultzberg M, Theodorsson E, Kreicbergs A. Increased levels of substance P and calcitonin gene-related peptide in rat adjuvant arthritis: a combined immunohistochemical and radioimmunoassay analysis. Arthritis Rheum 1995;38:699-709.
19. Kennedy AS, Raleigh JA, Perez GM, Calkins DP, Thrall DE, Novotny DB, et al. Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays. Int J Radiat Oncol Biol Phys 1997;37:897-905.
20. Hassl A, Aspock H. Purification of egg yolk immunoglobulins: a two-step procedure using hydrophobic interaction chromatography and gel filtration. J Immunol Methods 1988;110:225-8.
21. 3 synthesis in macrophages from inflammatory arthritic joints. Int J Immunother 1994;10:1-9.
22. Smith SJ, Hayes ME, Selby PL, Mawer EB. Autocrine control of vitamin D metabolism in synovial cells from arthritic patients. Ann Rheum Dis 1999;58:372-8.
23. Abeyama K, Kawahara K, Iino S, Hamada T, Arimura S, Matsushita K, et al. Antibiotic cyclic AMP signaling by "primed" leukocytes confers anti-inflammatory cytoprotection. J Leukoc Biol 2003;74:908-15.
24. Meshkini A, Yazdanparast R. Induction of megakaryocytic differentiation in chronic myelogenous leukemia cell K562 by 3-hydrogenkwadaphnin. J Biochem Mol Biol 2007;40:944-51.
25. Kobayashi T, Okamoto K, Kobata T, Hasunuma T, Sumida T, Nishioka K. Tumor necrosis factor α regulation of the Fas-mediated apoptosis-signaling pathway in synovial cells. Arthritis Rheum 1999;42:519-26.
26. Koehler NK, Genain CP, Giesser B, Hauser SL. The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study. J Immunol 2002;168:5920-7.
27. Bokarewa M, Nagaev I, Dahlberg L, Smith U, Tarkowski A. Resistin, an adipokine with potent proinflammatory properties. J Immunol 2005;74:5789-95.
28. Strunk J, Heinemann E, Neeck G, Schmidt KL, Lange U. A new approach to studying angiogenesis in rheumatoid arthritis by means of power Doppler ultrasonography and measurement of serum vascular endothelial growth factor. Rheumatology (Oxford) 2004;43:1480-3.
29. Yamada S, Inoue K, Yakabe K, Imaizumi H, Maruyama I. High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2. Clin Chem 2003;49:1535-7.
30. Mansson B, Carey D, Alini M, Ionescu M, Rosenberg LC, Poole AR, et al. Cartilage and bone metabolism in rheumatoid arthritis: differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. J Clin Invest 1995;95:1071-7.
31. Brook I, Controni G. Rapid diagnosis of septic arthritis by quantitative analysis of joint fluid lactic acid with a monotest lactate kit. J Clin Microbiol 1978;8:676-9.
32. Hinman RS, Crossley KM, McConnell J, Bennell KL. Does the application of tape influence quadriceps sensorimotor function in knee osteoarthritis? Rheumatology (Oxford) 2004;43:331-6.
33. Kortekangas P, Peltola O, Toivanen A, Aro HT. Synovial fluid L-lactic acid in acute arthritis of the adult knee joint. Scand J Rheumatol 1995;24:98-101.
34. Nishimura K, Solchaga LA, Caplan AI, Yoo JU, Goldberg VM, Johnstone B. Chondroprogenitor cells of synovial tissue. Arthritis Rheum 1999;42:2631-7.
35. Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, et al. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003;22:5551-60.
36. Loeser RF. Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide [editorial]. Arthritis Rheum 2006;54:1357-60.
37. Roux CH, Guillemin F, Boini S, Longuetaud F, Arnault N, Hercberg S, et al. Impact of musculoskeletal disorders on quality of life: an inception cohort study. Ann Rheum Dis 2005;64:606-11.
38. Suurmeijer TP, Waltz M, Mourn T, Guillemin F, van Sonderen FL, Briancon S, et al. Quality of life profiles in the first years of rheumatoid arthritis: results from the EURIDISS longitudinal study. Arthritis Rheum 2001;45:111-21.
39. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998;93:165-76.
40. Roodman GD. Regulation of osteoclast differentiation. Ann N Y Acad Sci 2006;1068:100-9.
41. Turner RT, Evans GL, Wakley GK. Reduced chondroclast differentiation results in increased cancellous bone volume in estrogen-treated growing rats. Endocrinology 1994;134:461-6.
42. Giatromanolaki A, Sivridis E, Maltezos E, Athanassou N, Papazoglou D, Gatter KC, et al. Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis. Arthritis Res Ther 2003;5:193-201.
43. Wei XQ, Charles IG, Smith A, Ure J, Feng GJ, Huang FP, et al. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 1995;375:408-11.
44. Palmer LA, Doctor A, Chhabra P, Sheram ML, Laubach VE, Karlinsey MZ, et al. S-nitrosothiols signal hypoxia-mimetic vascular pathology. J Clin Invest 2007;117:2592-601.
45. Varia MA, Calkins-Adams DP, Rinker LH, Kennedy AS, Novotny DB, Fowler WC, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol 1998;71:270-7.
46. Hoppe G, Talcott KE, Bhattacharya SK, Crabb JW, Sears JE. Molecular basis for the redox control of nuclear transport of the structural chromatin protein HMGB1. Exp Cell Res 2006;312:3526-38.