Differential analyses of angiogenesis and expression of growth factors in micro- and macrovascular endothelial cells of type 2 diabetic rats

Life Sciences

Volumn 84, Issue 7-8, 2009, Pages 240-249

  Wang, X H ^a   Chen, S F ^a   Jin, H M ^a   Hu, R M ^b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Angiogenesis; Flk 1; Flt 1; GK rat; Microvascular endothelial cells; Type 2 diabetes; VEGF

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; BASIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; TIE 1 RECEPTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; AORTIC ENDOTHELIAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GOTO KAKIZAKI RAT; MYOCARDIAL MICROVASCULAR ENDOTHELIAL CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT; WOUND HEALING;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

RATTUS; RATTUS NORVEGICUS;

EID: 58249116901     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.12.010     Document Type: Article

References (49)

1. Abaci A., Oguzhan A., Kahraman S., Eryol N.K., Unal S., Arinc H., and Ergin A. Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation 99 17 (1999) 2239-2242
2. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 2 (2004) 281-297
3. Barzilay J.I., Kronmal R.A., Bittner V., Eaker E., Evans C., and Foster E.D. Coronary artery disease and coronary artery bypass grafting in diabetic patients aged > or = 65 years (report from the Coronary Artery Surgery Study [CASS] Registry). American Journal of Cardiology 74 4 (1994) 334-339
4. Bitto A., Minutoli L., Galeano M.R., Altavilla D., Polito F., Fiumara T., Calo M., Lo Cascio P., Zentilin L., Giacca M., and Squadrito F. Angiopoietin-1 gene transfer improves the impaired wound healing of the genetically diabetic mice without increasing VEGF expression. Clinical Science (London) 114 12 (2008) 707-718
5. Boodhwani M., Sodha N.R., Mieno S., Xu S.H., Feng J., Ramlawi B., Clements R.T., and Sellke F.W. Functional, cellular, and molecular characterization of the angiogenic response to chronic myocardial ischemia in diabetes. Circulation 116 11 Suppl (2007) I31-37
6. Chen S.F., Li S.H., and Ding F.Y. Three drugs inhibit phospholipase A2-induced high permeability of endothelial monolayers. Zhongguo Yao Li Xue Bao 15 4 (1994) 299-302
7. Cheng B., Liu H.W., Fu X.B., Sun T.Z., and Sheng Z.Y. Recombinant human platelet-derived growth factor enhanced dermal wound healing by a pathway involving ERK and c-fos in diabetic rats. Journal of Dermatological Science 45 3 (2007) 193-201
8. Cho C.H., Sung H.K., Kim K.T., Cheon H.G., Oh G.T., Hong H.J., Yoo O.J., and Koh G.Y. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proceedings of the National Academy of Sciences of the United States of America 103 13 (2006) 4946-4951
9. Chou E., Suzuma I., Way K.J., Opland D., Clermont A.C., Naruse K., Suzuma K., Bowling N.L., Vlahos C.J., Aiello L.P., and King G.L. Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation 105 3 (2002) 373-379
10. Chung A.W., Hsiang Y.N., Matzke L.A., McManus B.M., van Breemen C., and Okon E.B. Reduced expression of vascular endothelial growth factor paralleled with the increased angiostatin expression resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in human type 2 diabetic arterial vasculature. Circulation Research 99 2 (2006) 140-148
11. Duffy A., Liew A., O'Sullivan J., Avalos G., Samali A., and O'Brien T. Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins. Endothelium 13 1 (2006) 9-16
12. Duraisamy Y., Slevin M., Smith N., Bailey J., Zweit J., Smith C., Ahmed N., and Gaffney J. Effect of glycation on basic fibroblast growth factor induced angiogenesis and activation of associated signal transduction pathways in vascular endothelial cells: possible relevance to wound healing in diabetes. Angiogenesis 4 4 (2001) 277-288
13. Emanueli C., Caporali A., Krankel N., Cristofaro B., Van Linthout S., and Madeddu P. Type-2 diabetic Lepr(db/db) mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia. Frontiers in Bioscience 12 (2007) 2003-2012
14. Ettenson D.S., and Gotlieb A.I. Centrosomes, microtubules, and microfilaments in the reendothelialization and remodeling of double-sided in vitro wounds. Laboratory Investigation 66 6 (1992) 722-733
15. Facchiano F., D'Arcangelo D., Russo K., Fogliano V., Mennella C., Ragone R., Zambruno G., Carbone V., Ribatti D., Peschle C., Capogrossi M.C., and Facchiano A. Glycated fibroblast growth factor-2 is quickly produced in vitro upon low-millimolar glucose treatment and detected in vivo in diabetic mice. Molecular Endocrinology 20 11 (2006) 2806-2818
16. Farhangkhoee H., Khan Z.A., Kaur H., Xin X., Chen S., and Chakrabarti S. Vascular endothelial dysfunction in diabetic cardiomyopathy: pathogenesis and potential treatment targets. Pharmacology & Therapeutics 111 2 (2006) 384-399
17. Galli J., Fakhrai-Rad H., Kamel A., Marcus C., Norgren S., and Luthman H. Pathophysiological and genetic characterization of the major diabetes locus in GK rats. Diabetes 48 12 (1999) 2463-2470
18. Giannini S., Cresci B., Manuelli C., Pala L., and Rotella C.M. Diabetic microangiopathy: IGFBP control endothelial cell growth by a common mechanism in spite of their species specificity and tissue peculiarity. Journal of Endocrinological Investigation 29 8 (2006) 754-763
19. Goto Y., Kakizaki M., and Masaki N. Production of spontaneous diabetic rats by repetition of selective breeding. Tohoku Journal of Experimental Medicine 119 1 (1976) 85-90
20. Gu J.W., and Adair T.H. Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells. American Journal of Physiology 273 2 Pt 2 (1997) H628-633
21. Gustafsson T., and Kraus W.E. Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathology. Frontiers of Bioscience 6 (2001) D75-89
22. Harry L.E., and Paleolog E.M. From the cradle to the clinic: VEGF in developmental, physiological, and pathological angiogenesis. Birth Defects Res C Embryo Today 69 4 (2003) 363-374
23. Janssen U., Phillips A.O., and Floege J. Rodent models of nephropathy associated with type II diabetes. Journal of Nephrology 12 3 (1999) 159-172
24. Janssen U., Vassiliadou A., Riley S.G., Phillips A.O., and Floege J. The quest for a model of type II diabetes with nephropathy: the Goto Kakizaki rat. Journal of Nephrology 17 6 (2004) 769-773
25. Kappas N.C., Zeng G., Chappell J.C., Kearney J.B., Hazarika S., Kallianos K.G., Patterson C., Annex B.H., and Bautch V.L. The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. Journal of Cell Biology 181 5 (2008) 847-858
26. King G.L., Buzney S.M., Kahn C.R., Hetu N., Buchwald S., Macdonald S.G., and Rand L.I. Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels. Journal of Clinical Investigation 71 4 (1983) 974-979
27. Kuehbacher A., Urbich C., Zeiher A.M., and Dimmeler S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circulation Research 101 1 (2007) 59-68
28. Li H., Fu X., Zhang L., Huang Q., Wu Z., and Sun T. Research of PDGF-BB gel on the wound healing of diabetic rats and its pharmacodynamics. Journal of Surgical Research 145 1 (2008) 41-48
29. Marfella R., Esposito K., Nappo F., Siniscalchi M., Sasso F.C., Portoghese M., Di Marino M.P., Baldi A., Cuzzocrea S., Di Filippo C., Barboso G., Baldi F., Rossi F., D'Amico M., and Giugliano D. Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes. Diabetes 53 9 (2004) 2383-2391
30. Melidonis A., Tournis S., Kouvaras G., Baltaretsou E., Hadanis S., Hajissavas I., Tsatsoulis A., and Foussas S. Comparison of coronary collateral circulation in diabetic and nondiabetic patients suffering from coronary artery disease. Clinical Cardiology 22 7 (1999) 465-471
31. Michaud S.E., Dussault S., Groleau J., Haddad P., and Rivard A. Cigarette smoke exposure impairs VEGF-induced endothelial cell migration: role of NO and reactive oxygen species. Journal of Molecular and Cellular Cardiology 41 2 (2006) 275-284
32. Movassat J., Saulnier C., Serradas P., and Portha B. Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat. Diabetologia 40 8 (1997) 916-925
33. Ning Y.X., Wang X.H., Jin H.M., Zhao F.D., and Yin L.H. Study on the cytological characteristics of rat myocardium microvascular endothelial cells in culture of primary passage by microarray. Chinese Journal of Pathophysiology 21 12 (2005) 2295-2300
34. Okada H., Woodcock-Mitchell J., Mitchell J., Sakamoto T., Marutsuka K., Sobel B.E., and Fujii S. Induction of plasminogen activator inhibitor type 1 and type 1 collagen expression in rat cardiac microvascular endothelial cells by interleukin-1 and its dependence on oxygen-centered free radicals. Circulation 97 21 (1998) 2175-2182
35. Okruhlicova L., Tribulova N., Weismann P., and Sotnikova R. Ultrastructure and histochemistry of rat myocardial capillary endothelial cells in response to diabetes and hypertension. Cell Research 15 7 (2005) 532-538
36. Pollman M.J., Naumovski L., and Gibbons G.H. Endothelial cell apoptosis in capillary network remodeling. Journal of Cellular Physiology 178 3 (1999) 359-370
37. Poy M.N., Eliasson L., Krutzfeldt J., Kuwajima S., Ma X., Macdonald P.E., Pfeffer S., Tuschl T., Rajewsky N., Rorsman P., and Stoffel M. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432 7014 (2004) 226-230
38. Rabinovsky E.D., and Draghia-Akli R. Insulin-like growth factor I plasmid therapy promotes in vivo angiogenesis. Molecular Theraphy 9 1 (2004) 46-55
39. Roberts D.M., Kearney J.B., Johnson J.H., Rosenberg M.P., Kumar R., and Bautch V.L. The vascular endothelial growth factor (VEGF) receptor Flt-1 (VEGFR-1) modulates Flk-1 (VEGFR-2) signaling during blood vessel formation. American Journal of Pathology 164 5 (2004) 1531-1535
40. Rymaszewski Z., Szymanski P.T., Abplanalp W.A., Myatt L., Di Salvo J., and Cohen R.M. Human retinal vascular cells differ from umbilical cells in synthetic functions and their response to glucose. Proceedings of the Society for Experimental Biology and Medicine 199 2 (1992) 183-191
41. Sasso F.C., Carbonara O., Persico E., D'Ambrosio R., Coppola L., Nasti R., Campana B., Moschella S., Torella R., and Cozzolino D. Increased vascular endothelial growth factor mRNA expression in the heart of streptozotocin-induced diabetic rats. Metabolism 52 6 (2003) 675-678
42. Sasso F.C., Torella D., Carbonara O., Ellison G.M., Torella M., Scardone M., Marra C., Nasti R., Marfella R., Cozzolino D., Indolfi C., Cotrufo M., Torella R., and Salvatore T. Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease. Journal of the American College of Cardiology 46 5 (2005) 827-834
43. Semenza G.L. HIF-1 and mechanisms of hypoxia sensing. Current Opinion in Cell Biology 13 2 (2001) 167-171
44. Tirabassi R.S., Flanagan J.F., Wu T., Kislauskis E.H., Birckbichler P.J., and Guberski D.L. The BBZDR/Wor rat model for investigating the complications of type 2 diabetes mellitus. ILAR Journal 45 3 (2004) 292-302
45. Toblli J.E., Cao G., DeRosa G., Di Gennaro F., and Forcada P. Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats. American Journal of Hypertension 17 2 (2004) 172-180
46. Waltenberger J. Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications. Cardiovascular Research 49 3 (2001) 554-560
47. Wu G., Mannam A.P., Wu J., Kirbis S., Shie J.L., Chen C., Laham R.J., Sellke F.W., and Li J. Hypoxia induces myocyte-dependent COX-2 regulation in endothelial cells: role of VEGF. American Journal of Physiology. Heart and Circulatory Physiology 285 6 (2003) H2420-2429
48. Wu L., Fan J., and Belasco J.G. MicroRNAs direct rapid deadenylation of mRNA. Proceedings of the National Academy of Sciences of the United States of America 103 11 (2006) 4034-4039
49. Yarom R., Zirkin H., Stammler G., and Rose A.G. Human coronary microvessels in diabetes and ischaemia. Morphometric study of autopsy material. Journal of Pathology 166 3 (1992) 265-270