-
1
-
-
84858077267
-
The medical care costs of obesity: An instrumental variables approach
-
J. Cawley, and C. Meyerhoefer The medical care costs of obesity: an instrumental variables approach J. Health Econ. 31 2012 219 230
-
(2012)
J. Health Econ.
, vol.31
, pp. 219-230
-
-
Cawley, J.1
Meyerhoefer, C.2
-
2
-
-
67749129442
-
Obesity and overweight
-
WHO
-
WHO Obesity and overweight In Fact Sheet 311 2012
-
(2012)
Fact Sheet
, vol.311
-
-
-
3
-
-
0033977443
-
Genomics, genes, and environmental interaction: The role of exercise
-
M.S. Bray Genomics, genes, and environmental interaction: the role of exercise J. Appl. Physiol. 88 2000 788 792 (Pubitemid 30097127)
-
(2000)
Journal of Applied Physiology
, vol.88
, Issue.2
, pp. 788-792
-
-
Bray, M.S.1
-
4
-
-
33750510903
-
The obesity pipeline: Current strategies in the development of anti-obesity drugs
-
DOI 10.1038/nrd2136, PII NRD2136
-
D. Cooke, and S. Bloom The obesity pipeline: current strategies in the development of anti-obesity drugs Nat. Rev. Drug Discov. 5 2006 919 931 (Pubitemid 44660605)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.11
, pp. 919-931
-
-
Cooke, D.1
Bloom, S.2
-
5
-
-
0002636658
-
Protein kinase C: A structurally related family of enzymes
-
R.M. Epand, D.S. Lester, Ellis Horwood
-
P.J. Parker Protein kinase C: a structurally related family of enzymes R.M. Epand, D.S. Lester, Protein Kinase C: Current Concepts and Future Perspectives 1992 Ellis Horwood 3 24
-
(1992)
Protein Kinase C: Current Concepts and Future Perspectives
, pp. 3-24
-
-
Parker, P.J.1
-
6
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Y. Nishizuka Protein kinase C and lipid signaling for sustained cellular responses FASEB J. 9 1995 484 496
-
(1995)
FASEB J.
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
7
-
-
0028811653
-
Protein kinase C: Structure, function, and regulation
-
A.C. Newton Protein kinase C: structure, function, and regulation J. Biol. Chem. 270 1995 28495 28498
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28495-28498
-
-
Newton, A.C.1
-
8
-
-
41149161288
-
PKC isozymes in chronic cardiac disease: Possible therapeutic targets?
-
DOI 10.1146/annurev.pharmtox.48.121806.154902
-
E. Churchill, G. Budas, A. Vallentin, T. Koyanagi, D. Mochly-Rosen, and H. Khaner PKC isozymes in chronic cardiac disease: possible therapeutic targets? Annu. Rev. Pharmacol. Toxicol. 48 2008 569 599 (Pubitemid 351738164)
-
(2008)
Annual Review of Pharmacology and Toxicology
, vol.48
, pp. 569-599
-
-
Churchill, E.1
Budas, G.2
Vallentin, A.3
Koyanagi, T.4
Mochly-Rosen, D.5
-
9
-
-
84886092889
-
The tail wagging the dog-regulation of lipid metabolism by protein kinase C
-
C. Schmitz-Peiffer The tail wagging the dog-regulation of lipid metabolism by protein kinase C FEBS J. 280 2013 5371 5383
-
(2013)
FEBS J.
, vol.280
, pp. 5371-5383
-
-
Schmitz-Peiffer, C.1
-
10
-
-
0023278635
-
Expression and properties of two types of protein kinase C: Alternative splicing from a single gene
-
Y. Ono, U. Kikkawa, K. Ohita, T. Fujit, T. Kurokawa, Y. Asaoka, K. Sekiguchi, K. Ase, K. Igarashi, and Y. Nishizuka Expression and properties of two types of protein kinase C: alternative splicing from a single gene Science 236 1987 1116 1120 (Pubitemid 17113258)
-
(1987)
Science
, vol.236
, Issue.4805
, pp. 1116-1120
-
-
Ono, Y.1
Kikkawa, U.2
Ogita, K.3
-
11
-
-
0035213641
-
AGC protein kinase phosphorylation and protein kinase C
-
DOI 10.1042/0300-5127:0290860
-
P.J. Parker, and S.J. Parkinson AGC protein kinase phosphorylation and protein kinase C Biochem. Soc. Trans. 29 2001 860 863 (Pubitemid 33131794)
-
(2001)
Biochemical Society Transactions
, vol.29
, Issue.6
, pp. 860-863
-
-
Parker, P.J.1
Parkinson, S.J.2
-
12
-
-
0037337159
-
Regulation of the ABC kinases by phosphorylation: Protein kinase C as a paradigm
-
DOI 10.1042/BJ20021626
-
A.C. Newton Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm Biochem. J. 370 2003 361 371 (Pubitemid 36315124)
-
(2003)
Biochemical Journal
, vol.370
, Issue.2
, pp. 361-371
-
-
Newton, A.C.1
-
13
-
-
66349096059
-
Lipid activation of protein kinases
-
A.C. Newton Lipid activation of protein kinases J. Lipid Res. 50 2009 S266 S271
-
(2009)
J. Lipid Res.
, vol.50
-
-
Newton, A.C.1
-
14
-
-
33751570046
-
Structure of the catalytic domain of human protein kinase C β II complexed with a bisindolylmaleimide inhibitor
-
DOI 10.1021/bi061128h
-
N. Grodsky, D. Bouzida, R. Love, J. Jensen, B. Nodes, J. Nonomiya, and S. Grant Structure of the catalytic domain of human protein kinase C β II complexed with a bisindolylmaleimide inhibitor Biogeosciences 45 2006 13970 13981 (Pubitemid 44846186)
-
(2006)
Biochemistry
, vol.45
, Issue.47
, pp. 13970-13981
-
-
Grodsky, N.1
Li, Y.2
Bouzida, D.3
Love, R.4
Jensen, J.5
Nodes, B.6
Nonomiya, J.7
Grant, S.8
-
15
-
-
78650942010
-
Crystal structure and allosteric activation of protein kinase CβII
-
T.A. Leonard, B. Rozycki, L.F. Saidi, G. Hummer, and J.H. Hurley Crystal structure and allosteric activation of protein kinase CβII Cell 144 2011 55 66
-
(2011)
Cell
, vol.144
, pp. 55-66
-
-
Leonard, T.A.1
Rozycki, B.2
Saidi, L.F.3
Hummer, G.4
Hurley, J.H.5
-
16
-
-
0030764985
-
Activation of protein kinase C by tyrosine phosphorylation in response to H2O2
-
DOI 10.1073/pnas.94.21.11233
-
H. Konishi, M. Tanaka, Y. Takemura, H. Matsuzaki, Y. Ono, U. Kikkawa, and Y. Nishizuka Activation of protein kinase C by tyrosine phosphorylation in response to H2O2 Proc. Natl. Acad. Sci. U. S. A. 94 1997 11233 11237 (Pubitemid 27450981)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.21
, pp. 11233-11237
-
-
Konishi, H.1
Tanaka, M.2
Takemura, Y.3
Matsuzaki, H.4
Ono, Y.5
Kikkawa, U.6
Nishizuka, Y.7
-
18
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
DOI 10.1016/j.cub.2004.06.054, PII S0960982204004713
-
D.D. Sarbassov, S.M. Ali, D.H. Kim, D.A. Guertin, R.R. Latek, H. Erdjument-Bromage, P. Tempst, and D.M. Sabatini Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton Curr. Biol. 14 2004 1296 1302 (Pubitemid 38991819)
-
(2004)
Current Biology
, vol.14
, Issue.14
, pp. 1296-1302
-
-
Dos D. Sarbassov1
Ali, S.M.2
Kim, D.-H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
19
-
-
47949104258
-
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation, and signaling
-
T.K. Ikenoue, K. Inoki, Q. Yang, X. Zhou, and K.L. Guan Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation, and signaling EMBO J. 27 2008 1919 1931
-
(2008)
EMBO J.
, vol.27
, pp. 1919-1931
-
-
Ikenoue, T.K.1
Inoki, K.2
Yang, Q.3
Zhou, X.4
Guan, K.L.5
-
20
-
-
64149128633
-
The chaperons Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail
-
C.M. Gould, N. Kannan, S.S. Taylor, and A.C. Newton The chaperons Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail J. Biol. Chem. 284 2008 4921 4935
-
(2008)
J. Biol. Chem.
, vol.284
, pp. 4921-4935
-
-
Gould, C.M.1
Kannan, N.2
Taylor, S.S.3
Newton, A.C.4
-
21
-
-
36349030360
-
Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase
-
D. Chen, C. Gould, R. Garza, T. Gao, R.Y. Hampton, and A.C. Newton Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase J. Biol. Chem. 282 2007 33776 33780
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33776-33780
-
-
Chen, D.1
Gould, C.2
Garza, R.3
Gao, T.4
Hampton, R.Y.5
Newton, A.C.6
-
22
-
-
40749152802
-
Differential recruitment of PKC isoforms in HeLa cells during redox stress
-
A. Rimessi, R. Rizutto, and P. Pinton Differential recruitment of PKC isoforms in HeLa cells during redox stress Cell Stress Chaperones 12 2007 291 298
-
(2007)
Cell Stress Chaperones
, vol.12
, pp. 291-298
-
-
Rimessi, A.1
Rizutto, R.2
Pinton, P.3
-
23
-
-
0033996388
-
AGEs induce oxidative stress and activate protein kinase C-beta(II) in neonatal mesangial cells
-
V. Scivittaro, M.B. Ganz, and M.F. Weiss AGEs induce oxidative stress and activate protein kinase C-beta(II) in neonatal mesangial cells Am. J. Physiol. Renal Physiol. 278 2000 F676 F683
-
(2000)
Am. J. Physiol. Renal Physiol.
, vol.278
-
-
Scivittaro, V.1
Ganz, M.B.2
Weiss, M.F.3
-
24
-
-
77957364479
-
Oxidative stress stimulates apoptosis and activates NF-κB in osteoblastic cells via a PKCβ/p66shc signaling cascade: Counter regulation by estrogens or androgens
-
M. Almeida, L. Han, E. Ambrogni, S.M. Bartell, and S.C. Manolagas Oxidative stress stimulates apoptosis and activates NF-κB in osteoblastic cells via a PKCβ/p66shc signaling cascade: counter regulation by estrogens or androgens Mol. Endocrinol. 24 2010 2030 2037
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 2030-2037
-
-
Almeida, M.1
Han, L.2
Ambrogni, E.3
Bartell, S.M.4
Manolagas, S.C.5
-
25
-
-
77955916237
-
Redox control of protein kinase C: Cell and disease-specific aspects
-
C. Giogi, C. Agnoletto, C. Baldini, A. Bononi, M. Bonora, S. Marchi, S. Missiroli, S. Patergnani, F. Poletti, A. Rimessi, B. Zavan, and P. Pinton Redox control of protein kinase C: cell and disease-specific aspects Antioxid. Redox Signal. 13 2010 1051 1085
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1051-1085
-
-
Giogi, C.1
Agnoletto, C.2
Baldini, C.3
Bononi, A.4
Bonora, M.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Poletti, F.9
Rimessi, A.10
Zavan, B.11
Pinton, P.12
-
26
-
-
0034190297
-
Protein kinase C signaling and oxidative stress
-
DOI 10.1016/S0891-5849(00)00221-5, PII S0891584900002215
-
R. Gopalakrishna, and S. Jaken Protein kinase C signaling and oxidative stress Free Radic. Biol. Med. 9 2000 1349 1361 (Pubitemid 30621479)
-
(2000)
Free Radical Biology and Medicine
, vol.28
, Issue.9
, pp. 1349-1361
-
-
Gopalakrishna, R.1
Jaken, S.2
-
27
-
-
66149093022
-
Loss of protein kinase Cβ function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance
-
W. Huang, R. Bansode, M. Mehta, and K.D. Mehta Loss of protein kinase Cβ function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance Hepatology 49 2009 1525 1536
-
(2009)
Hepatology
, vol.49
, pp. 1525-1536
-
-
Huang, W.1
Bansode, R.2
Mehta, M.3
Mehta, K.D.4
-
28
-
-
0026781998
-
Cloning and characterization of the major promoter of the human protein kinase Cβ gene
-
L.M. Obeid, G.C. Blobe, L.A. Karolak, and Y.A. Hannun Cloning and characterization of the major promoter of the human protein kinase Cβ gene J. Biol. Chem. 267 1992 20804 20810
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20804-20810
-
-
Obeid, L.M.1
Blobe, G.C.2
Karolak, L.A.3
Hannun, Y.A.4
-
29
-
-
8544251332
-
Protein kinase C beta;II regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo
-
DOI 10.1074/jbc.M407701200
-
Y. Liu, W. Su, E.A. Thompson, M. Leitges, N.R. Murray, and A.P. Fields Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo J. Biol. Chem. 279 2004 45556 45563 (Pubitemid 39491542)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.44
, pp. 45556-45563
-
-
Liu, Y.1
Su, W.2
Thompson, E.A.3
Leitges, M.4
Murray, N.R.5
Fields, A.P.6
-
30
-
-
0028932995
-
Autoregulation of cloned human protein kinase C beta and gamma gene promoters in U937 cells
-
J. Mahajna, P. King, P. Parker, and J. Haley Autoregulation of cloned human protein kinase C beta and gamma gene promoters in U937 cells DNA Cell Biol. 14 1995 213 222
-
(1995)
DNA Cell Biol.
, vol.14
, pp. 213-222
-
-
Mahajna, J.1
King, P.2
Parker, P.3
Haley, J.4
-
31
-
-
84866000382
-
PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation
-
K. Hagiwara, H. Ito, T. Murate, Y. Miyata, H. Ohashi, and H. Nagai PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation Genes Chromosom. Cancer 51 2012 1024 1036
-
(2012)
Genes Chromosom. Cancer
, vol.51
, pp. 1024-1036
-
-
Hagiwara, K.1
Ito, H.2
Murate, T.3
Miyata, Y.4
Ohashi, H.5
Nagai, H.6
-
32
-
-
0026739568
-
Positive and negative regulation of the transcription of the human protein kinase C β gene
-
Y.S. Niino, S. Ohno, and K. Suzuki Positive and negative regulation of the transcription of the human protein kinase C β gene J. Biol. Chem. 267 1992 6158 6163
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 6158-6163
-
-
Niino, Y.S.1
Ohno, S.2
Suzuki, K.3
-
33
-
-
79959540803
-
Disruption of the murine protein kinase Cβ gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolism
-
W. Huang, R.R. Bansode, Y. Xie, L. Rowland, M. Mehta, and K.D. Mehta Disruption of the murine protein kinase Cβ gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolism J. Biol. Chem. 286 2011 22795 22805
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22795-22805
-
-
Huang, W.1
Bansode, R.R.2
Xie, Y.3
Rowland, L.4
Mehta, M.5
Mehta, K.D.6
-
34
-
-
22044458643
-
Increases in intracellular calcium dephosphorylate histone H3 at serine 10 in human hepatoma cells: Potential role of protein phosphatase 2A-protein kinase CβII complex
-
DOI 10.1002/jcp.20372
-
W. Huang, S. Batra, S. Korrapati, V. Mishra, and K.D. Mehta Increases in intracellular calcium dephosphorylate histone H3 at serine 10 in human hepatoma cells: potential role of protein phosphatase 2A-protein kinase CbII complex J. Cell. Physiol. 205 2005 37 46 (Pubitemid 41262849)
-
(2005)
Journal of Cellular Physiology
, vol.205
, Issue.1
, pp. 37-46
-
-
Huang, W.1
Batra, S.2
Atkins, B.A.3
Mishra, V.4
Mehta, K.D.5
-
35
-
-
3442887046
-
Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner
-
DOI 10.1194/jlr.M400088-JLR200
-
W. Huang, V. MIshra, S. Batra, I. Dillon, and K.D. Mehta Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a PKC-dependent manner J. Lipid Res. 45 2004 1519 1527 (Pubitemid 39006980)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.8
, pp. 1519-1527
-
-
Huang, W.1
Mishra, V.2
Batra, S.3
Dillon, I.4
Mehta, K.D.5
-
36
-
-
0038281516
-
Pp90RSK- and protein kinase C-dependent pathway regulates p42/44MAPK-induced LDL receptor transcription in HepG2 cells
-
DOI 10.1194/jlr.M200302-JLR200
-
G. Kapoor, B. Atkins, A. Radominska-Pandya, B. Dave, and K.D. Mehta pp90rsk and protein kinase C participate in p42/44MAPK-induced LDL receptor expression in HepG2 cells J. Lipid Res. 44 2003 584 593 (Pubitemid 37279708)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.3
, pp. 584-593
-
-
Kapoor, G.S.1
Golden, C.2
Atkins, B.3
Mehta, K.D.4
-
37
-
-
38049134621
-
PKCβ deficiency increases fatty acid oxidation and reduces fat storage
-
R. Bansode, W. Huang, S. Roy, M. Mehta, and K.D. Mehta PKCβ deficiency increases fatty acid oxidation and reduces fat storage J. Biol. Chem. 283 2008 231 236
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 231-236
-
-
Bansode, R.1
Huang, W.2
Roy, S.3
Mehta, M.4
Mehta, K.D.5
-
38
-
-
84863278878
-
PKCβ deficiency attenuates obesity syndrome of ob/ob mice by promoting white adipose tissue remodeling
-
W. Huang, R.R. Bansode, N. Bal, M. Mehta, and K.D. Mehta PKCβ deficiency attenuates obesity syndrome of ob/ob mice by promoting white adipose tissue remodeling J. Lipid Res. 53 2012 368 378
-
(2012)
J. Lipid Res.
, vol.53
, pp. 368-378
-
-
Huang, W.1
Bansode, R.R.2
Bal, N.3
Mehta, M.4
Mehta, K.D.5
-
39
-
-
77950245008
-
Transcriptional control of brown fat development
-
S. Kajimura, P. Seale, B. M. Spiegelman, Transcriptional control of brown fat development. Cell Metab. 11 () 257-262.
-
Cell Metab.
, vol.11
, pp. 257-262
-
-
Kajimura, S.1
Seale, P.2
Spiegelman, B.M.3
-
40
-
-
64349121056
-
Transcriptional control of brown adipocyte development and physiological function-of mice and men
-
P. Seale, S. Kajimura, and B.M. Spiegelman Transcriptional control of brown adipocyte development and physiological function-of mice and men Genes Dev. 23 2009 788 797
-
(2009)
Genes Dev.
, vol.23
, pp. 788-797
-
-
Seale, P.1
Kajimura, S.2
Spiegelman, B.M.3
-
41
-
-
33748366392
-
Regulatory circuits controlling white versus brown adipocyte differentiation
-
DOI 10.1042/BJ20060402
-
J.B. Hansen, and K. Kristiansen Regulatory circuits controlling white versus brown adipocyte differentiation Biochem. J. 398 2006 153 168 (Pubitemid 44338472)
-
(2006)
Biochemical Journal
, vol.398
, Issue.2
, pp. 153-168
-
-
Hansen, J.B.1
Kristiansen, K.2
-
42
-
-
84873518501
-
Adaptive thermogenesis in adipocytes: Is beige the new brown?
-
J. Wu, P. Cohen, and B.M. Spiegelman Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev. 27 2013 234 250
-
(2013)
Genes Dev.
, vol.27
, pp. 234-250
-
-
Wu, J.1
Cohen, P.2
Spiegelman, B.M.3
-
43
-
-
20244383573
-
Protein kinase C-mediated down-regulation of β1- adrenergic receptor gene expression in rat C6 glioma cells
-
Z. Li, V.A. Vaidya, J.D. Alvaro, P.A. Iredale, R. Hsu, G. Hoffman, P.K. Curran Fitzgerald, C.A. Machida, P.H. Fishman, and R.S. Duman Protein kinase C-mediated down regulation of beta1-adrenergic receptor gene expression in rat C6 glioma cells Mol. Pharmacol. 54 1998 14 21 (Pubitemid 28337582)
-
(1998)
Molecular Pharmacology
, vol.54
, Issue.1
, pp. 14-21
-
-
Li, Z.1
Vaidya, V.A.2
Alvaro, J.D.3
Iredale, P.A.4
Hsu, R.5
Hoffman, G.6
Fitzgerald, L.7
Curran, P.K.8
Machida, C.A.9
Fishman, P.H.10
Duman, R.S.11
-
44
-
-
0028358937
-
Transcriptional down-regulation by insulin of the β3- adrenergic receptor expression in 3T3-F442A adipocytes: A mechanism for repressing the cAMP signaling pathway
-
DOI 10.1073/pnas.91.12.5677
-
B. Feve, K. Elhadri, A. Quignard-Boulange, and J. Pairault Transcriptional down-regulation by insulin of the beta3-adrenergic receptor expression in 3T3-F442A adipocytes: a mechanism for repressing the cAMP signaling pathway Proc. Natl. Acad. Sci. U. S. A. 91 1994 5677 5681 (Pubitemid 24174391)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.12
, pp. 5677-5681
-
-
Feve, B.1
Elhadri, K.2
Quignard-Boulange, A.3
Pairault, J.4
-
45
-
-
0028958853
-
Long term phorbol ester treatment down-regulates the beta3-adrenergic receptor in 3T3-F442A adipocytes
-
B. Feve, F. Pietri-Rouxel, K. Hadri, M.F. Drumare, and A.D. Strosberg Long term phorbol ester treatment down-regulates the beta3-adrenergic receptor in 3T3-F442A adipocytes J. Biol. Chem. 270 1995 10952 10959
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10952-10959
-
-
Feve, B.1
Pietri-Rouxel, F.2
Hadri, K.3
Drumare, M.F.4
Strosberg, A.D.5
-
46
-
-
77957113550
-
Weight gain related to treatment with atypical antipsychotics is due to activation of PKCβ
-
C. Pavan, V. Vindigni, L. Michelotto, A. Rimessi, G. Abatangelo, R. Corvito, P. Pinton, and B. Zavan Weight gain related to treatment with atypical antipsychotics is due to activation of PKCβ Pharmacogenetics J. 10 2010 408 417
-
(2010)
Pharmacogenetics J.
, vol.10
, pp. 408-417
-
-
Pavan, C.1
Vindigni, V.2
Michelotto, L.3
Rimessi, A.4
Abatangelo, G.5
Corvito, R.6
Pinton, P.7
Zavan, B.8
-
47
-
-
33748692452
-
Different roles of protein kinase C-βI and -δ in the regulation of adipocyte differentiation
-
DOI 10.1016/j.biocel.2006.06.009, PII S1357272506002135
-
Y. Zhou, D. Wang, F. Li, J. Shi, and J. Song Different roles of protein kinase C-βI and -δ in the regulation of adipocyte differentiation Int. J. Biochem. 38 2006 2151 2163 (Pubitemid 44397623)
-
(2006)
International Journal of Biochemistry and Cell Biology
, vol.38
, Issue.12
, pp. 2151-2163
-
-
Zhou, Y.1
Wang, D.2
Li, F.3
Shi, J.4
Song, J.5
-
48
-
-
69549124621
-
Developmentally spliced PKCβII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport
-
10.1016/j.bbrc.2009.08.063
-
E. Kleiman, G. Carter, T. Ghansah, N.A. Patel, and D.R. Cooper Developmentally spliced PKCβII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport Biochem. Biophys. Res. Commun. 388 2009 554 559 10.1016/j.bbrc.2009.08.063
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.388
, pp. 554-559
-
-
Kleiman, E.1
Carter, G.2
Ghansah, T.3
Patel, N.A.4
Cooper, D.R.5
-
49
-
-
47549105527
-
Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase CβII in the diabetic fat tissue
-
Z. Liberman, B. Plotkin, T. Tennenbaum, and H. Eldar-Finkelman Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase CβII in the diabetic fat tissue Am. J. Physiol. Endocrinol. Metab. 294 2008 E1169 E1177
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
-
-
Liberman, Z.1
Plotkin, B.2
Tennenbaum, T.3
Eldar-Finkelman, H.4
-
50
-
-
77953498526
-
Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin
-
T. Yamamoto, K. Watanabe, N. Inoue, T. Nakagawa, N. Ishigaki, T. Matsuzaka, Y. Takeuchi, K. Kobayashi, S. Yatoh, A. Takahashi, H. Suzuki, N. Yahagi, T. Gotoda, N. Yamada, and H. Shimano Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin J. Lipid Res. 51 2010 1859 1870
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1859-1870
-
-
Yamamoto, T.1
Watanabe, K.2
Inoue, N.3
Nakagawa, T.4
Ishigaki, N.5
Matsuzaka, T.6
Takeuchi, Y.7
Kobayashi, K.8
Yatoh, S.9
Takahashi, A.10
Suzuki, H.11
Yahagi, N.12
Gotoda, T.13
Yamada, N.14
Shimano, H.15
-
51
-
-
38049023940
-
Identification of a functional protein kinase Cβ promoter polymorphism in humans related to insulin resistance
-
M.A. Osterhoff, S. Heuer, M. Pfeiffer, J. Tasic, S. Kaiser, F. Isken, J. Spranger, M.O. Weickert, M. Mohlig, and F. Pfeiffer Identification of a functional protein kinase Cβ promoter polymorphism in humans related to insulin resistance Mol. Genet. Metab. 93 2008 210 215
-
(2008)
Mol. Genet. Metab.
, vol.93
, pp. 210-215
-
-
Osterhoff, M.A.1
Heuer, S.2
Pfeiffer, M.3
Tasic, J.4
Kaiser, S.5
Isken, F.6
Spranger, J.7
Weickert, M.O.8
Mohlig, M.9
Pfeiffer, F.10
-
53
-
-
34848851922
-
Angiogenesis modulates adipogenesis and obesity
-
DOI 10.1172/JCI32239
-
Y. Cao Angiogenesis modulates adipogenesis and obesity J. Clin. Invest. 117 2007 2362 2368 (Pubitemid 47494333)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2362-2368
-
-
Cao, Y.1
-
54
-
-
77956226516
-
The PKCbeta/HuR/VEGF pathway in diabetic retinopathy
-
M. Amadio, C. Bucolo, G.M. Leggio, F. Drago, S. Govoni, and A. Pascale The PKCbeta/HuR/VEGF pathway in diabetic retinopathy Biochem. Pharmacol. 80 2010 1230 1237
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1230-1237
-
-
Amadio, M.1
Bucolo, C.2
Leggio, G.M.3
Drago, F.4
Govoni, S.5
Pascale, A.6
-
55
-
-
34250773451
-
Mechanisms of obesity-associated insulin resistance: Many choices on the menu
-
DOI 10.1101/gad.1550907
-
M. Qatanani, and M.A. Lazar Mechanisms of obesity-associated insulin resistance: many choices on the menu Genes Dev. 21 2007 1443 1455 (Pubitemid 46955717)
-
(2007)
Genes and Development
, vol.21
, Issue.12
, pp. 1443-1455
-
-
Qatanani, M.1
Lazar, M.A.2
-
56
-
-
0036310147
-
Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance - Is insulin resistance initiated in the adipose tissue?
-
DOI 10.1038/sj.ijo.0802028
-
U. Smith Impaired ("diabetic") insulin signaling and action occur in fat cells long before glucose intolerance - is insulin resistance initiated in the adipose tissue? Int. J. Obes. Relat. Metab. Disord. 26 2002 897 904 (Pubitemid 34756170)
-
(2002)
International Journal of Obesity
, vol.26
, Issue.7
, pp. 897-904
-
-
Smith, U.1
-
57
-
-
77954859197
-
The role of mitochondria in the pathogenesis of type 2 diabetes
-
M.E. Patti, and S. Corvera The role of mitochondria in the pathogenesis of type 2 diabetes Endocr. Rev. 31 2010 364 395
-
(2010)
Endocr. Rev.
, vol.31
, pp. 364-395
-
-
Patti, M.E.1
Corvera, S.2
-
59
-
-
33644821858
-
Mitochondria are impaired in the adipocytes of type 2 diabetic mice
-
DOI 10.1007/s00125-006-0170-2
-
H.J. Choo, J.H. Kim, O.B. Kwon, C.S. Lee, J.Y. Mun, S.S. Han, Y.S. Yoon, G. Yoon, K.M. Choi, and Y.G. Ko Mitochondrial are impaired in the adipocytes of type 2 diabetic mice Diabetologia 49 2006 784 791 (Pubitemid 43361881)
-
(2006)
Diabetologia
, vol.49
, Issue.4
, pp. 784-791
-
-
Choo, H.-J.1
Kim, J.-H.2
Kwon, O.-B.3
Lee, C.S.4
Mun, J.Y.5
Han, S.S.6
Yoon, Y.-S.7
Yoon, G.8
Choi, K.-M.9
Ko, Y.-G.10
-
60
-
-
34347391646
-
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone
-
DOI 10.2337/db06-1135
-
J.X. Rong, Y. Qiu, M.K. Hansen, L. Zhu, V. Zhang, M. Xie, Y. Okamoto, M.D. Mattie, H. Higashiyama, S. Asano, J.C. Strum, and T.E. Ryan Adipose mitochondrial biogenesis in suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone Diabetes 56 2007 1751 1760 (Pubitemid 47025441)
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1751-1760
-
-
Rong, J.X.1
Qiu, Y.2
Hansen, M.K.3
Zhu, L.4
Zhang, V.5
Xie, M.6
Okamoto, Y.7
Mattie, M.D.8
Higashiyama, H.9
Asano, S.10
Strum, J.C.11
Ryan, T.E.12
-
61
-
-
33748305621
-
Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-α
-
DOI 10.2337/db05-1421
-
I. Dahlman, M. Forsgren, A. Sjogren, E.A. Nordstrom, M. Kaaman, E. Naslund, A. Attersand, and P. Amer Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha Diabetes 55 2006 1792 1799 (Pubitemid 44324134)
-
(2006)
Diabetes
, vol.55
, Issue.6
, pp. 1792-1799
-
-
Dahlman, I.1
Forsgren, M.2
Sjogren, A.3
Nordstrom, E.A.4
Kaaman, M.5
Naslund, E.6
Attersand, A.7
Arner, P.8
-
62
-
-
28744448555
-
Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro
-
DOI 10.1210/jc.2005-1024
-
L. Bogacka, B. Ukropcova, M. McNeil, J.M. Gimble, and S.R. Smith Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro J. Clin. Endocrinol. Metab. 90 2005 6650 6656 (Pubitemid 41759328)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.12
, pp. 6650-6656
-
-
Bogacka, I.1
Ukropcova, B.2
McNeil, M.3
Gimble, J.M.4
Smith, S.R.5
-
63
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
DOI 10.1172/JCI200421625
-
S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Y. Yamada, Y. Nakajima, O. Nakayama, M. Makishima, M. Matsuda, and I. Shimomura Increased oxidative stress in obesity and its impact on metabolic syndrome J. Clin. Invest. 114 2004 1752 1761 (Pubitemid 40385531)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.12
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
64
-
-
0037342568
-
Obesity and systemic oxidative stress: Clinical correlates of oxidative stress in the Framingham study
-
DOI 10.1161/01.ATV.0000058402.34138.11
-
J.F. Keaney, M.G. Larson, R.S. Vasan, P.W. Wilson, and I. Lipinska et al. Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study Arterioscler. Thromb. Vasc. Biol. 23 2003 434 439 (Pubitemid 36337219)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.3
, pp. 434-439
-
-
Keaney Jr., J.F.1
Larson, M.G.2
Vasan, R.S.3
Wilson, P.W.F.4
Lipinska, I.5
Corey, D.6
Massaro, J.M.7
Sutherland, P.8
Vita, J.A.9
Benjamin, E.J.10
-
65
-
-
33846817351
-
Protein kinase C β and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
-
DOI 10.1126/science.1135380
-
P. Pinton, A. Rimessi, S. Marchi, F. Orsini, E. Migliaccio, M. Giorgio, C. Contursi, S. Minucci, F. Mantovani, M.R. Wieckowski, G. Del Sal, P.G. Pelicci, and R. Rizzuto Protein kinase C β and prolylisomerase I regulate mitochondrial effects of the life-span determinant p66Shc Science 315 2007 659 663 (Pubitemid 46214712)
-
(2007)
Science
, vol.315
, Issue.5812
, pp. 659-663
-
-
Pinton, P.1
Rimessi, A.2
Marchi, S.3
Orsini, F.4
Migliaccio, E.5
Giorgio, M.6
Contursi, C.7
Minucci, S.8
Mantovani, F.9
Wieckowski, M.R.10
Del Sal, G.11
Pelicci, P.G.12
Rizzuto, R.13
-
66
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
DOI 10.1073/pnas.0336359100
-
C. Napoli, I. Martin-Padura, and F. de Nigris et al. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet Proc. Natl. Acad. Sci. U. S. A. 100 2003 2112 2116 (Pubitemid 36254582)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
De Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.G.10
-
67
-
-
57749091893
-
P66shc-generated oxidative signal promotes fat accumulation
-
I. Berniakovich, M. Trinei, and M. Stendardo et al. p66shc-generated oxidative signal promotes fat accumulation J. Biol. Chem. 283 2008 34283 34293
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34283-34293
-
-
Berniakovich, I.1
Trinei, M.2
Stendardo, M.3
-
68
-
-
78651344799
-
The Shc locus regulates insulin signaling and adiposity in mammals
-
A.A. Tomilov, J.J. Ramsey, and K. Hagopian et al. The Shc locus regulates insulin signaling and adiposity in mammals Aging Cell 10 2011 55 65
-
(2011)
Aging Cell
, vol.10
, pp. 55-65
-
-
Tomilov, A.A.1
Ramsey, J.J.2
Hagopian, K.3
-
69
-
-
84884329320
-
The protein kinase Cβ and the mitochondrial axis as key regulators of autophagy
-
S. Patergnani, S. Marchi, A. Rimessi, M. Bonora, C. Giorgi, K.D. Mehta, and P. Pinton The protein kinase Cβ and the mitochondrial axis as key regulators of autophagy Autophagy 9 2013 1367 1385
-
(2013)
Autophagy
, vol.9
, pp. 1367-1385
-
-
Patergnani, S.1
Marchi, S.2
Rimessi, A.3
Bonora, M.4
Giorgi, C.5
Mehta, K.D.6
Pinton, P.7
-
70
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
-
Y. Zhang, S. Goldman, R. Baerga, Y. Zhao, M. Komatsu, and S. Jin Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis Proc. Natl. Acad. Sci. U. S. A. 2009 106 2009 19860 19865
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.2009
, Issue.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.6
-
71
-
-
84887849242
-
Defective regulation of adipose tissue autophagy in obesity
-
V.S. Nunez, V.S. Rodrigues, F.S. Gomes, R.F. Moura, S.C. Victorio, B. Bombassaro, E.A. Chaim, J.C. Pareja, B. Geloneze, L.A. Velloso, and E.P. Araujo Defective regulation of adipose tissue autophagy in obesity Int. J. Obes. 37 2013 1473 1480
-
(2013)
Int. J. Obes.
, vol.37
, pp. 1473-1480
-
-
Nunez, V.S.1
Rodrigues, V.S.2
Gomes, F.S.3
Moura, R.F.4
Victorio, S.C.5
Bombassaro, B.6
Chaim, E.A.7
Pareja, J.C.8
Geloneze, B.9
Velloso, L.A.10
Araujo, E.P.11
-
72
-
-
84870170324
-
Autophagy activity is up-regulated in adipose tissue of obese individuals and modulates proinflammatory cytokine expression
-
H.J. Jansen, P. van Essen, T. Koenen, L.A. Joosten, M.G. Netea, C.J. Tack, and R. Stienstra Autophagy activity is up-regulated in adipose tissue of obese individuals and modulates proinflammatory cytokine expression Endocrinology 2012 153 2012 5866 5874
-
(2012)
Endocrinology
, vol.2012
, Issue.153
, pp. 5866-5874
-
-
Jansen, H.J.1
Van Essen, P.2
Koenen, T.3
Joosten, L.A.4
Netea, M.G.5
Tack, C.J.6
Stienstra, R.7
-
73
-
-
79959354999
-
Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
-
D.R. Green, L. Galluzzi, and G. Kroemer Mitochondria and the autophagy-inflammation-cell death axis in organismal aging Science 333 2011 1109 1112
-
(2011)
Science
, vol.333
, pp. 1109-1112
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
74
-
-
0028175887
-
Identification of nuclear βiI protein kinase C as a mitotic lamin kinase
-
V.L. Goss, B.A. Hocevar, L.J. Thompson, C.A. Stratton, D.J. Burns, and A.P. Fields Identification of nuclear βII protein kinase C as a mitotic lamin kinase J. Biol. Chem. 269 1994 19074 19080
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19074-19080
-
-
Goss, V.L.1
Hocevar, B.A.2
Thompson, L.J.3
Stratton, C.A.4
Burns, D.J.5
Fields, A.P.6
-
75
-
-
77950460256
-
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4
-
E. Metzer, A. Imhof, D. Patel, P. Kahl, K. Hoffmeyer, N. Friedrichs, J.M. Muller, H. Greschik, J. Kirfel, S. Ji, N. Kunowska, C. Beisenherz-Huss, T. Gunther, R. Buettner, and R. Schule Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4 Nature 464 2010 792 796
-
(2010)
Nature
, vol.464
, pp. 792-796
-
-
Metzer, E.1
Imhof, A.2
Patel, D.3
Kahl, P.4
Hoffmeyer, K.5
Friedrichs, N.6
Muller, J.M.7
Greschik, H.8
Kirfel, J.9
Ji, S.10
Kunowska, N.11
Beisenherz-Huss, C.12
Gunther, T.13
Buettner, R.14
Schule, R.15
-
76
-
-
70350353211
-
Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene
-
H. Teng, R.D. Ballim, S. Mowla, and S. Prince Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene J. Biol. Chem. 284 2009 26368 26376
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26368-26376
-
-
Teng, H.1
Ballim, R.D.2
Mowla, S.3
Prince, S.4
-
77
-
-
51549118740
-
PKCβII augments NF-κB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation
-
(35-4-3514)
-
D.L. Clarke, A. Sutcliffe, K. Deacon, D. Bradbury, L. Corbett, and A.J. Knox PKCβII augments NF-κB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation J. Immunol. 181 2008 (35-4-3514)
-
(2008)
J. Immunol.
, vol.181
-
-
Clarke, D.L.1
Sutcliffe, A.2
Deacon, K.3
Bradbury, D.4
Corbett, L.5
Knox, A.J.6
-
78
-
-
0027165075
-
Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site
-
J.C. Hsieh, P.W. Jurutka, S. Makajima, M.A. Galligan, C.A. Haussler, Y. Shimizu, N. Shimizu, G.K. Whitfield, and M.R. Haussler Phosphorylation of the human vitamin D receptor by protein kinase C: biochemical and functional evaluation of the serine 51 recognition site J. Biol. Chem. 268 1993 15118 15126 (Pubitemid 23206664)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.20
, pp. 15118-15126
-
-
Hsieh, J.-C.1
Jurutka, P.W.2
Nakajima, S.3
Galligan, M.A.4
Haussler, C.A.5
Shimizu, Y.6
Shimizu, N.7
Whitfield, G.K.8
Haussler, M.R.9
-
79
-
-
0037154156
-
Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization
-
DOI 10.1073/pnas.022644499
-
K. Suzuma, N. Takahara, I. Suzuma, K. Isshiki, K. Ueki, M. Leitges, L.P. Aiello, and G.L. King Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal vascularization Proc. Natl. Acad. Sci. U. S. A. 99 2002 721 726 (Pubitemid 34106577)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.2
, pp. 721-726
-
-
Suzuma, K.1
Takahara, N.2
Suzuma, I.3
Isshiki, K.4
Ueki, K.5
Leitges, M.6
Aiello, L.P.7
King, G.L.8
-
80
-
-
10244235304
-
Protein kinase Cβ1 and protein kinase Cβ2 activate p57 mitogen- activated protein kinase and block differentiation in colon carcinoma cells
-
S. Sauma, Z. Yan, S. Ohno, and E. Friedman Protein kinase C beta 1 and protein kinase C beta 2 activate p57 mitogen-activated protein kinase and block differentiation in colon carcinoma cells Cell Growth Differ. 7 1996 587 594 (Pubitemid 26360757)
-
(1996)
Cell Growth and Differentiation
, vol.7
, Issue.5
, pp. 587-594
-
-
Sauma, S.1
Zhongfa, Y.2
Ohno, S.3
Friedman, E.4
-
81
-
-
0033838459
-
Insulin-activated protein kinase Cβ bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells
-
DOI 10.1128/MCB.20.17.6323-6333.2000
-
P. Formisano, F. Oriente, F. Flory, M. Caruso, C. Miele, M.A. Maitan, F. Andreozzi, G. Vigliotta, G. Condorelli, and F. Beguinot Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells Mol. Cell. Biol. 20 2000 6323 6333 (Pubitemid 30650219)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.17
, pp. 6323-6333
-
-
Formisano, P.1
Oriente, F.2
Fiory, F.3
Caruso, M.4
Miele, C.5
Maitan, M.A.6
Andreozzi, F.7
Vigliotta, G.8
Condorelli, G.9
Beguinot, F.10
-
82
-
-
0036647038
-
Phosphoinositide 3-kinase mediates protein kinase C βII mRNA destabilization in rat A10 smooth muscle cell cultures exposed to high glucose
-
DOI 10.1016/S0003-9861(02)00208-4, PII S0003986102002084
-
N.A. Patel, M. Yamamoto, P. Illingsworth, D. Mancu, K. Mebert, D.S. Chappell, J.E. Watson, and D.R. Cooper Phosphoinositide 3-kinase mediates protein kinase C beta II mRNA destabilization in rat A10 smooth muscle cell cultures exposed to high glucose Arch. Biochem. Biophys. 403 2002 111 120 (Pubitemid 34848284)
-
(2002)
Archives of Biochemistry and Biophysics
, vol.403
, Issue.1
, pp. 111-120
-
-
Patel, N.A.1
Yamamoto, M.2
Illingworth, P.3
Mancu, D.4
Mebert, K.5
Chappell, D.S.6
Watson, J.E.7
Cooper, D.R.8
-
83
-
-
33644781862
-
Activation of vascular protein kinase C-beta; inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance
-
K. Naruse, C. Rask-Madsen, N. Takahara, S.W. Ha, K. Suzuma, K.J. Way, J.R. Jacobs, A.C. Clermont, K. Ueki, Y. Ohshiro, J. Zhang, A.B. Goldfine, and G.L. King Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance Diabetes 55 2006 691 698 (Pubitemid 43343225)
-
(2006)
Diabetes
, vol.55
, Issue.3
, pp. 691-698
-
-
Naruse, K.1
Rask-Madsen, C.2
Takahara, N.3
Ha, S.-W.4
Suzuma, K.5
Way, K.J.6
Jacobs, J.R.C.7
Clermont, A.C.8
Ueki, K.9
Ohshiro, Y.10
Zhang, J.11
Goldfine, A.B.12
King, G.L.13
-
84
-
-
62149150630
-
PKC-beta 1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesengial cells
-
D. Wu, F. Peng, B. Zhang, A.J. Ingram, D.J. Kelly, R.E. Gilbert, B. Gao, and J.C. Krepinsky PKC-beta 1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesengial cells J. Am. Soc. Nephrol. 20 2009 554 566
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 554-566
-
-
Wu, D.1
Peng, F.2
Zhang, B.3
Ingram, A.J.4
Kelly, D.J.5
Gilbert, R.E.6
Gao, B.7
Krepinsky, J.C.8
-
85
-
-
38949200925
-
Involvement of protein kinase C β-extracellular signal-regulating kinase1/2/p38 mitogen-activated protein kinase-heat shock protein 27 activation in hepatocellular carcinoma cell motility and invasion
-
DOI 10.1111/j.1349-7006.2007.00702.x
-
K. Guo, Y. Liu, H. Zhou, Z. Dai, J. Zhang, R. Sun, J. Chen, Q. Sun, W. Lu, X. Kang, and P. Chen Involvement of protein kinase C beta-extracellular signal-regulating kinase 1/2/p38 mitogen-activated protein kinase-heat shock protein 27 activation in hepatocellular carcinoma cell motility and invasion Cancer Sci. 99 2008 486 496 (Pubitemid 351228564)
-
(2008)
Cancer Science
, vol.29
, Issue.3
, pp. 486-496
-
-
Guo, K.1
Liu, Y.2
Zhou, H.3
Dai, Z.4
Zhang, J.5
Sun, R.6
Chen, J.7
Sun, Q.8
Lu, W.9
Kang, X.10
Chen, P.11
-
86
-
-
0031978984
-
Exercise, glucose transport, and insulin sensitivity
-
DOI 10.1146/annurev.med.49.1.235
-
L.J. Goodyear, and B.B. Kahn Exercise, glucose transport, and insulin sensitivity Annu. Rev. Med. 49 1998 235 261 (Pubitemid 28197452)
-
(1998)
Annual Review of Medicine
, vol.49
, pp. 235-261
-
-
Goodyear, L.J.1
Kahn, B.B.2
-
87
-
-
84892589850
-
Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice
-
X. Rao, J. Zhong, X. Xu, B. Jordan, S. Maurya, Z. Braunstein, T.Y. Wang, W. Huang, S. Agarawal, M. Periasamy, S. Rajagopalan, K.D. Mehta, and Q. Sun Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice PLoS One 8 2013 e81364
-
(2013)
PLoS One
, vol.8
, pp. 81364
-
-
Rao, X.1
Zhong, J.2
Xu, X.3
Jordan, B.4
Maurya, S.5
Braunstein, Z.6
Wang, T.Y.7
Huang, W.8
Agarawal, S.9
Periasamy, M.10
Rajagopalan, S.11
Mehta, K.D.12
Sun, Q.13
-
88
-
-
77953928057
-
Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain
-
A.M. Hennige, M. Heni, J. Machann, H. Staiger, T. Sartorius, M. Hoene, R. Lehmann, C. Weigert, A. Peter, A. Bornemann, S. Kroeber, A. Pujol, S. Franckhauser, F. Bosch, F. Schick, R. Lammers, and H.U. Haring Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain J. Cell. Mol. Med. 14 2010 903 913
-
(2010)
J. Cell. Mol. Med.
, vol.14
, pp. 903-913
-
-
Hennige, A.M.1
Heni, M.2
Machann, J.3
Staiger, H.4
Sartorius, T.5
Hoene, M.6
Lehmann, R.7
Weigert, C.8
Peter, A.9
Bornemann, A.10
Kroeber, S.11
Pujol, A.12
Franckhauser, S.13
Bosch, F.14
Schick, F.15
Lammers, R.16
Haring, H.U.17
-
89
-
-
0032934826
-
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: A 1H NMR spectroscopy study
-
DOI 10.1007/s001250051123
-
M. Krssak, K.F. Petersen, K.A. Dresner, L. DiPietro, S.M. Vogel, and D.L. Rothman et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study Diabetologia 42 1999 113 116 (Pubitemid 29039748)
-
(1999)
Diabetologia
, vol.42
, Issue.1
, pp. 113-116
-
-
Krssak, M.1
Falk Petersen, K.2
Dresner, A.3
DiPietro, L.4
Vogel, S.M.5
Rothman, D.L.6
Shulman, G.I.7
Roden, M.8
-
90
-
-
77952468064
-
Activation of protein kinase C isoforms and its impact on diabetic complications
-
P. Geraldes, and G.L. King Activation of protein kinase C isoforms and its impact on diabetic complications Circ. Res. 106 2010 1319 1331
-
(2010)
Circ. Res.
, vol.106
, pp. 1319-1331
-
-
Geraldes, P.1
King, G.L.2
-
91
-
-
0031860340
-
Protein kinase C activation and the development of diabetic complications
-
DOI 10.2337/diabetes.47.6.859
-
D. Koya, and G.L. King Protein kinase C activation and the development of the complications of diabetes Diabetes 47 1998 859 866 (Pubitemid 28255657)
-
(1998)
Diabetes
, vol.47
, Issue.6
, pp. 859-866
-
-
Koya, D.1
King, G.L.2
-
92
-
-
13344293711
-
Amelioration of vascular dysfunctions in diabetic rats by an oral PKC β inhibitor
-
H. Ishii, M.R. Jirousek, D. Koya, C. Takagi, P. Xia, A. Clermont, S.E. Bursell, T.S. Kern, L.M. Ballas, W.F. Heath, L.E. Stramm, E.P. Feener, and G.L. King Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor Science 272 1996 728 731 (Pubitemid 26000279)
-
(1996)
Science
, vol.272
, Issue.5262
, pp. 728-731
-
-
Ishii, H.1
Jirousek, M.R.2
Koya, D.3
Takagi, C.4
Xia, P.5
Clermont, A.6
Bursell, S.-E.7
Kern, T.S.8
Ballas, L.M.9
Heath, W.F.10
Stramm, L.E.11
Feener, E.P.12
King, G.L.13
-
93
-
-
84892671769
-
Ruboxistaurin: Review of safety and efficacy in the treatment of diabetic retinopathy
-
G. Javey, S.G. Schwartz, H.W. Flynn, L.P. Aiello, and M.J. Sheetz Ruboxistaurin: review of safety and efficacy in the treatment of diabetic retinopathy Clin. Med. Insights 2 2010 625 631
-
(2010)
Clin. Med. Insights
, vol.2
, pp. 625-631
-
-
Javey, G.1
Schwartz, S.G.2
Flynn, H.W.3
Aiello, L.P.4
Sheetz, M.J.5
-
94
-
-
58549113343
-
Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus
-
N.N. Mehta, M. Sheetz, K. Price, L. Comiskey, S. Amrutia, N. Iqbal, E.R. Mohler, and M.P. Reilly Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus Cardiovasc. Drugs Ther. 23 2009 17 24.
-
(2009)
Cardiovasc. Drugs Ther.
, vol.23
, pp. 17-24
-
-
Mehta, N.N.1
Sheetz, M.2
Price, K.3
Comiskey, L.4
Amrutia, S.5
Iqbal, N.6
Mohler, E.R.7
Reilly, M.P.8
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