메뉴 건너뛰기




Volumn 37, Issue 11, 2013, Pages 1473-1480

Defective regulation of adipose tissue autophagy in obesity

Author keywords

beclin; CHOP; GPR78; mTOR; p62; PERK

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 84887849242     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2013.27     Document Type: Article
Times cited : (99)

References (31)
  • 1
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444: 840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 3
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306: 457-461.
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Yilmaz, E.3    Lee, A.H.4    Iwakoshi, N.N.5    Ozdelen, E.6
  • 4
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010; 140: 900-917.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 5
    • 84855605795 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress, obesity and diabetes
    • Cnop M, Foufelle F, Velloso LA. Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 2012; 18: 59-68.
    • (2012) Trends Mol Med , vol.18 , pp. 59-68
    • Cnop, M.1    Foufelle, F.2    Velloso, L.A.3
  • 6
    • 58149484392 scopus 로고    scopus 로고
    • Inflammation and endoplasmic reticulum stress in obesity and diabetes
    • Hotamisligil GS. Inflammation and endoplasmic reticulum stress in obesity and diabetes. Int J Obes (Lond) 2008; 32(Suppl 7): S52-S54.
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 7
    • Hotamisligil, G.S.1
  • 7
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • Yang L, Li P, Fu S, Calay ES, Hotamisligil GS. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010; 11: 467-478.
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 8
    • 41749114288 scopus 로고    scopus 로고
    • Autophagy: Basic principles and relevance to disease
    • Kundu M, Thompson CB. Autophagy: basic principles and relevance to disease. Annu Rev Pathol 2008; 3: 427-455.
    • (2008) Annu Rev Pathol , vol.3 , pp. 427-455
    • Kundu, M.1    Thompson, C.B.2
  • 9
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 10
    • 34250864795 scopus 로고    scopus 로고
    • Protein turnover via autophagy: Implications for metabolism
    • Mizushima N, Klionsky DJ. Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr 2007; 27: 19-40.
    • (2007) Annu Rev Nutr , vol.27 , pp. 19-40
    • Mizushima, N.1    Klionsky, D.J.2
  • 13
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 15
    • 53549131963 scopus 로고    scopus 로고
    • A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery
    • Tang F, Watkins JW, Bermudez M, Gray R, Gaban A, Portie K et al. A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery. Autophagy 2008; 4: 874-886.
    • (2008) Autophagy , vol.4 , pp. 874-886
    • Tang, F.1    Watkins, J.W.2    Bermudez, M.3    Gray, R.4    Gaban, A.5    Portie, K.6
  • 17
    • 0026499896 scopus 로고
    • Gastrointestinal surgery for severe obesity: National institutes of health consensus development conference statement
    • Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement. Am J Clin Nutr 1992; 55(2 Suppl): 615S-619S.
    • (1992) Am J Clin Nutr , vol.55 , Issue.2 SUPPL.
  • 19
    • 0042767611 scopus 로고    scopus 로고
    • Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity
    • Rossmeisl M, Rim JS, Koza RA, Kozak LP. Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity. Diabetes 2003; 52: 1958-1966.
    • (2003) Diabetes , vol.52 , pp. 1958-1966
    • Rossmeisl, M.1    Rim, J.S.2    Koza, R.A.3    Kozak, L.P.4
  • 20
    • 33947618988 scopus 로고    scopus 로고
    • Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
    • De Souza CT, Araujo EP, Stoppiglia LF, Pauli JR, Ropelle E, Rocco SA et al. Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action. FASEB J 2007; 21: 1153-1163.
    • (2007) FASEB J , vol.21 , pp. 1153-1163
    • De Souza, C.T.1    Araujo, E.P.2    Stoppiglia, L.F.3    Pauli, J.R.4    Ropelle, E.5    Rocco, S.A.6
  • 21
    • 77954251401 scopus 로고    scopus 로고
    • Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes
    • Ost A, Svensson K, Ruishalme I, Brannmark C, Franck N, Krook H et al. Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes. Mol Med 2010; 16: 235-246.
    • (2010) Mol Med , vol.16 , pp. 235-246
    • Ost, A.1    Svensson, K.2    Ruishalme, I.3    Brannmark, C.4    Franck, N.5    Krook, H.6
  • 22
    • 73949124173 scopus 로고    scopus 로고
    • Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogen-esis
    • Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogen-esis. Proc Natl Acad Sci USA 2009; 106: 19860-19865.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19860-19865
    • Zhang, Y.1    Goldman, S.2    Baerga, R.3    Zhao, Y.4    Komatsu, M.5    Jin, S.6
  • 23
    • 75149123563 scopus 로고    scopus 로고
    • Autophagy and adipogenesis: Implications in obesity and type II diabetes
    • Goldman S, Zhang Y, Jin S. Autophagy and adipogenesis: implications in obesity and type II diabetes. Autophagy 2010; 6: 179-181.
    • (2010) Autophagy , vol.6 , pp. 179-181
    • Goldman, S.1    Zhang, Y.2    Jin, S.3
  • 24
    • 81055140893 scopus 로고    scopus 로고
    • Feedback on fat: P62-mTORC1-autophagy connections
    • Moscat J, Diaz-Meco MT. Feedback on fat: p62-mTORC1-autophagy connections. Cell 2011; 147: 724-727.
    • (2011) Cell , vol.147 , pp. 724-727
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 25
    • 77956834462 scopus 로고    scopus 로고
    • Autophagy: A potential link between obesity and insulin resistance
    • Codogno P, Meijer AJ. Autophagy: a potential link between obesity and insulin resistance. Cell Metab 2010; 11: 449-451.
    • (2010) Cell Metab , vol.11 , pp. 449-451
    • Codogno, P.1    Meijer, A.J.2
  • 26
    • 0038120873 scopus 로고    scopus 로고
    • Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients
    • Kopp HP, Kopp CW, Festa A, Krzyzanowska K, Kriwanek S, Minar E et al. Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients. Arterioscler Thromb Vasc Biol 2003; 23: 1042-1047.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1042-1047
    • Kopp, H.P.1    Kopp, C.W.2    Festa, A.3    Krzyzanowska, K.4    Kriwanek, S.5    Minar, E.6
  • 27
    • 77955364936 scopus 로고    scopus 로고
    • Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: A study with the euglycemic-hyperinsulinemic clamp
    • Lima MM, Pareja JC, Alegre SM, Geloneze SR, Kahn SE, Astiarraga BD et al. Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: a study with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab 2010; 95: 3871-3875.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 3871-3875
    • Lima, M.M.1    Pareja, J.C.2    Alegre, S.M.3    Geloneze, S.R.4    Kahn, S.E.5    Astiarraga, B.D.6
  • 28
    • 79959453241 scopus 로고    scopus 로고
    • Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects
    • van de Sande-Lee S, Pereira FR, Cintra DE, Fernandes PT, Cardoso AR, Garlipp CR et al. Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects. Diabetes 2011; 60: 1699-1704.
    • (2011) Diabetes , vol.60 , pp. 1699-1704
    • Van De Sande-Lee, S.1    Pereira, F.R.2    Cintra, D.E.3    Fernandes, P.T.4    Cardoso, A.R.5    Garlipp, C.R.6
  • 29
    • 84858281134 scopus 로고    scopus 로고
    • PGC1alpha gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery
    • Geloneze SR, Geloneze B, Morari J, Matos-Souza JR, Lima MM, Chaim EA et al. PGC1alpha gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery. Int J Obes (Lond) 2012; 36: 363-368.
    • (2012) Int J Obes (Lond) , vol.36 , pp. 363-368
    • Geloneze, S.R.1    Geloneze, B.2    Morari, J.3    Matos-Souza, J.R.4    Lima, M.M.5    Chaim, E.A.6
  • 31
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot JL, Hugol D et al. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 2006; 55: 1554-1561.
    • (2006) Diabetes , vol.55 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3    Guilhem, G.4    Bouillot, J.L.5    Hugol, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.