-
1
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444: 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
3
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306: 457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
4
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010; 140: 900-917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
5
-
-
84855605795
-
Endoplasmic reticulum stress, obesity and diabetes
-
Cnop M, Foufelle F, Velloso LA. Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 2012; 18: 59-68.
-
(2012)
Trends Mol Med
, vol.18
, pp. 59-68
-
-
Cnop, M.1
Foufelle, F.2
Velloso, L.A.3
-
6
-
-
58149484392
-
Inflammation and endoplasmic reticulum stress in obesity and diabetes
-
Hotamisligil GS. Inflammation and endoplasmic reticulum stress in obesity and diabetes. Int J Obes (Lond) 2008; 32(Suppl 7): S52-S54.
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.SUPPL. 7
-
-
Hotamisligil, G.S.1
-
7
-
-
77956400005
-
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
-
Yang L, Li P, Fu S, Calay ES, Hotamisligil GS. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010; 11: 467-478.
-
(2010)
Cell Metab
, vol.11
, pp. 467-478
-
-
Yang, L.1
Li, P.2
Fu, S.3
Calay, E.S.4
Hotamisligil, G.S.5
-
8
-
-
41749114288
-
Autophagy: Basic principles and relevance to disease
-
Kundu M, Thompson CB. Autophagy: basic principles and relevance to disease. Annu Rev Pathol 2008; 3: 427-455.
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 427-455
-
-
Kundu, M.1
Thompson, C.B.2
-
9
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
10
-
-
34250864795
-
Protein turnover via autophagy: Implications for metabolism
-
Mizushima N, Klionsky DJ. Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr 2007; 27: 19-40.
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 19-40
-
-
Mizushima, N.1
Klionsky, D.J.2
-
11
-
-
58049204465
-
Autophagy and pattern recognition receptors in innate immunity
-
Delgado M, Singh S, De Haro S, Master S, Ponpuak M, Dinkins C et al. Autophagy and pattern recognition receptors in innate immunity. Immunol Rev 2009; 227: 189-202.
-
(2009)
Immunol Rev
, vol.227
, pp. 189-202
-
-
Delgado, M.1
Singh, S.2
De Haro, S.3
Master, S.4
Ponpuak, M.5
Dinkins, C.6
-
13
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
14
-
-
79951690345
-
Altered autophagy in human adipose tissues in obesity
-
Kovsan J, Bluher M, Tarnovscki T, Kloting N, Kirshtein B, Madar L et al. Altered autophagy in human adipose tissues in obesity. J Clin Endocrinol Metab 2011; 96: E268-E277.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Kovsan, J.1
Bluher, M.2
Tarnovscki, T.3
Kloting, N.4
Kirshtein, B.5
Madar, L.6
-
15
-
-
53549131963
-
A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery
-
Tang F, Watkins JW, Bermudez M, Gray R, Gaban A, Portie K et al. A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery. Autophagy 2008; 4: 874-886.
-
(2008)
Autophagy
, vol.4
, pp. 874-886
-
-
Tang, F.1
Watkins, J.W.2
Bermudez, M.3
Gray, R.4
Gaban, A.5
Portie, K.6
-
17
-
-
0026499896
-
Gastrointestinal surgery for severe obesity: National institutes of health consensus development conference statement
-
Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement. Am J Clin Nutr 1992; 55(2 Suppl): 615S-619S.
-
(1992)
Am J Clin Nutr
, vol.55
, Issue.2 SUPPL.
-
-
-
18
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8: 445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
-
19
-
-
0042767611
-
Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity
-
Rossmeisl M, Rim JS, Koza RA, Kozak LP. Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity. Diabetes 2003; 52: 1958-1966.
-
(2003)
Diabetes
, vol.52
, pp. 1958-1966
-
-
Rossmeisl, M.1
Rim, J.S.2
Koza, R.A.3
Kozak, L.P.4
-
20
-
-
33947618988
-
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
-
De Souza CT, Araujo EP, Stoppiglia LF, Pauli JR, Ropelle E, Rocco SA et al. Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action. FASEB J 2007; 21: 1153-1163.
-
(2007)
FASEB J
, vol.21
, pp. 1153-1163
-
-
De Souza, C.T.1
Araujo, E.P.2
Stoppiglia, L.F.3
Pauli, J.R.4
Ropelle, E.5
Rocco, S.A.6
-
21
-
-
77954251401
-
Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes
-
Ost A, Svensson K, Ruishalme I, Brannmark C, Franck N, Krook H et al. Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes. Mol Med 2010; 16: 235-246.
-
(2010)
Mol Med
, vol.16
, pp. 235-246
-
-
Ost, A.1
Svensson, K.2
Ruishalme, I.3
Brannmark, C.4
Franck, N.5
Krook, H.6
-
22
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogen-esis
-
Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogen-esis. Proc Natl Acad Sci USA 2009; 106: 19860-19865.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.6
-
23
-
-
75149123563
-
Autophagy and adipogenesis: Implications in obesity and type II diabetes
-
Goldman S, Zhang Y, Jin S. Autophagy and adipogenesis: implications in obesity and type II diabetes. Autophagy 2010; 6: 179-181.
-
(2010)
Autophagy
, vol.6
, pp. 179-181
-
-
Goldman, S.1
Zhang, Y.2
Jin, S.3
-
24
-
-
81055140893
-
Feedback on fat: P62-mTORC1-autophagy connections
-
Moscat J, Diaz-Meco MT. Feedback on fat: p62-mTORC1-autophagy connections. Cell 2011; 147: 724-727.
-
(2011)
Cell
, vol.147
, pp. 724-727
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
25
-
-
77956834462
-
Autophagy: A potential link between obesity and insulin resistance
-
Codogno P, Meijer AJ. Autophagy: a potential link between obesity and insulin resistance. Cell Metab 2010; 11: 449-451.
-
(2010)
Cell Metab
, vol.11
, pp. 449-451
-
-
Codogno, P.1
Meijer, A.J.2
-
26
-
-
0038120873
-
Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients
-
Kopp HP, Kopp CW, Festa A, Krzyzanowska K, Kriwanek S, Minar E et al. Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients. Arterioscler Thromb Vasc Biol 2003; 23: 1042-1047.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1042-1047
-
-
Kopp, H.P.1
Kopp, C.W.2
Festa, A.3
Krzyzanowska, K.4
Kriwanek, S.5
Minar, E.6
-
27
-
-
77955364936
-
Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: A study with the euglycemic-hyperinsulinemic clamp
-
Lima MM, Pareja JC, Alegre SM, Geloneze SR, Kahn SE, Astiarraga BD et al. Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: a study with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab 2010; 95: 3871-3875.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 3871-3875
-
-
Lima, M.M.1
Pareja, J.C.2
Alegre, S.M.3
Geloneze, S.R.4
Kahn, S.E.5
Astiarraga, B.D.6
-
28
-
-
79959453241
-
Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects
-
van de Sande-Lee S, Pereira FR, Cintra DE, Fernandes PT, Cardoso AR, Garlipp CR et al. Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects. Diabetes 2011; 60: 1699-1704.
-
(2011)
Diabetes
, vol.60
, pp. 1699-1704
-
-
Van De Sande-Lee, S.1
Pereira, F.R.2
Cintra, D.E.3
Fernandes, P.T.4
Cardoso, A.R.5
Garlipp, C.R.6
-
29
-
-
84858281134
-
PGC1alpha gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery
-
Geloneze SR, Geloneze B, Morari J, Matos-Souza JR, Lima MM, Chaim EA et al. PGC1alpha gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery. Int J Obes (Lond) 2012; 36: 363-368.
-
(2012)
Int J Obes (Lond)
, vol.36
, pp. 363-368
-
-
Geloneze, S.R.1
Geloneze, B.2
Morari, J.3
Matos-Souza, J.R.4
Lima, M.M.5
Chaim, E.A.6
-
30
-
-
62749178966
-
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
-
Gregor MF, Yang L, Fabbrini E, Mohammed BS, Eagon JC, Hotamisligil GS et al. Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes 2009; 58: 693-700.
-
(2009)
Diabetes
, vol.58
, pp. 693-700
-
-
Gregor, M.F.1
Yang, L.2
Fabbrini, E.3
Mohammed, B.S.4
Eagon, J.C.5
Hotamisligil, G.S.6
-
31
-
-
33748314535
-
Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
-
Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot JL, Hugol D et al. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 2006; 55: 1554-1561.
-
(2006)
Diabetes
, vol.55
, pp. 1554-1561
-
-
Cancello, R.1
Tordjman, J.2
Poitou, C.3
Guilhem, G.4
Bouillot, J.L.5
Hugol, D.6
|