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Volumn 80, Issue 8, 2010, Pages 1230-1237

The PKCβ/HuR/VEGF pathway in diabetic retinopathy

Author keywords

Diabetes; Embryonic lethal abnormal vision protein; PKC; Retina; VEGF

Indexed keywords

EMBRYONIC LETHAL ABNORMAL VISION PROTEIN; GLUCOSE; HUR PROTEIN; MESSENGER RNA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA INHIBITOR; PROTEIN KINASE C BETA1; PROTEIN KINASE C BETA2; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; ELAV-LIKE PROTEIN 1; MEMBRANE ANTIGEN; PROTEIN KINASE C;

EID: 77956226516     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.06.033     Document Type: Article
Times cited : (102)

References (65)
  • 1
    • 39449130466 scopus 로고    scopus 로고
    • Update on the treatment of diabetic retinopathy
    • Wilkinson-Berka J.L., Miller A.G. Update on the treatment of diabetic retinopathy. Sci World J 2008, 8:98-120.
    • (2008) Sci World J , vol.8 , pp. 98-120
    • Wilkinson-Berka, J.L.1    Miller, A.G.2
  • 2
    • 0036460325 scopus 로고    scopus 로고
    • Diabetic retinopathy. A clinical update
    • Porta M., Bandello F. Diabetic retinopathy. A clinical update. Diabetologia 2002, 45:1617-1634.
    • (2002) Diabetologia , vol.45 , pp. 1617-1634
    • Porta, M.1    Bandello, F.2
  • 3
    • 66349093990 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N. Vascular endothelial growth factor. Arterioscler Thromb Vasc Biol 2009, 29:789-791.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 789-791
    • Ferrara, N.1
  • 4
    • 14944361800 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor in ocular health and disease
    • Adamis A.P., Shima D.T. The role of vascular endothelial growth factor in ocular health and disease. Retina 2005, 25:111-118.
    • (2005) Retina , vol.25 , pp. 111-118
    • Adamis, A.P.1    Shima, D.T.2
  • 5
    • 0042898974 scopus 로고
    • Vascular morphogenesis in the retina of the cat
    • Michaelson I.C. Vascular morphogenesis in the retina of the cat. J Anat 1948, 82:167-174.
    • (1948) J Anat , vol.82 , pp. 167-174
    • Michaelson, I.C.1
  • 6
    • 55849126672 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and diabetic complications
    • Wirostko B., Wong T.Y., Simó R. Vascular endothelial growth factor and diabetic complications. Prog Retin Eye Res 2008, 27:608-621.
    • (2008) Prog Retin Eye Res , vol.27 , pp. 608-621
    • Wirostko, B.1    Wong, T.Y.2    Simó, R.3
  • 8
    • 77956231461 scopus 로고    scopus 로고
    • ERK1/2 signaling pathways involved in VEGF release in diabetic rat retina
    • [Epub ahead of print], May
    • Ye X., Xu G., Chang Q., Fan J., Sun Z., Qin Y., et al. ERK1/2 signaling pathways involved in VEGF release in diabetic rat retina. Invest Ophthalmol Vis Sci 2010, (May). [Epub ahead of print].
    • (2010) Invest Ophthalmol Vis Sci
    • Ye, X.1    Xu, G.2    Chang, Q.3    Fan, J.4    Sun, Z.5    Qin, Y.6
  • 9
    • 37549062567 scopus 로고    scopus 로고
    • Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina
    • Yokota T., Utsunomiya K., Taniguchi K., Gojo A., Kurata H., Tajima N. Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina. Jpn J Ophthalmol 2007, 51:424-430.
    • (2007) Jpn J Ophthalmol , vol.51 , pp. 424-430
    • Yokota, T.1    Utsunomiya, K.2    Taniguchi, K.3    Gojo, A.4    Kurata, H.5    Tajima, N.6
  • 10
  • 11
    • 34250771556 scopus 로고    scopus 로고
    • The aging brain, a key target for the future: the protein kinase C involvement
    • Pascale A., Amadio M., Govoni S., Battaini F. The aging brain, a key target for the future: the protein kinase C involvement. Pharmacol Res 2007, 55:560-569.
    • (2007) Pharmacol Res , vol.55 , pp. 560-569
    • Pascale, A.1    Amadio, M.2    Govoni, S.3    Battaini, F.4
  • 12
    • 2942532719 scopus 로고    scopus 로고
    • Emerging targets for the pharmacology of learning and memory
    • Amadio M., Govoni S., Alkon D.L., Pascale A. Emerging targets for the pharmacology of learning and memory. Pharmacol Res 2004, 50:111-122.
    • (2004) Pharmacol Res , vol.50 , pp. 111-122
    • Amadio, M.1    Govoni, S.2    Alkon, D.L.3    Pascale, A.4
  • 13
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • Koya D., King G.L. Protein kinase C activation and the development of diabetic complications. Diabetes 1998, 47:859-866.
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 14
    • 0034852862 scopus 로고    scopus 로고
    • Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes
    • Idris I., Gray S., Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 2001, 44:659-673.
    • (2001) Diabetologia , vol.44 , pp. 659-673
    • Idris, I.1    Gray, S.2    Donnelly, R.3
  • 15
    • 0036939182 scopus 로고    scopus 로고
    • The potential role of PKC beta in diabetic retinopathy and macular edema
    • Aiello L.P. The potential role of PKC beta in diabetic retinopathy and macular edema. Surv Ophthalmol 2002, 47:S263-269.
    • (2002) Surv Ophthalmol , vol.47
    • Aiello, L.P.1
  • 16
    • 34250702110 scopus 로고    scopus 로고
    • The role of protein kinase C activation and the vascular complications of diabetes
    • Das Evcimen N., King G.L. The role of protein kinase C activation and the vascular complications of diabetes. Pharmacol Res 2007, 55:498-510.
    • (2007) Pharmacol Res , vol.55 , pp. 498-510
    • Das Evcimen, N.1    King, G.L.2
  • 17
    • 50949089640 scopus 로고    scopus 로고
    • Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway
    • Kim Y.H., Kim Y.S., Park C.H., Chung I.Y., Yoo J.M., Kim J.G., et al. Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway. Diabetes 2008, 57:2181-2190.
    • (2008) Diabetes , vol.57 , pp. 2181-2190
    • Kim, Y.H.1    Kim, Y.S.2    Park, C.H.3    Chung, I.Y.4    Yoo, J.M.5    Kim, J.G.6
  • 18
    • 39149083402 scopus 로고    scopus 로고
    • PKCbetaII/HuR/VEGF: a new molecular cascade in retinal pericytes for the regulation of VEGF gene expression
    • Amadio M., Scapagnini G., Lupo G., Drago F., Govoni S., Pascale A. PKCbetaII/HuR/VEGF: a new molecular cascade in retinal pericytes for the regulation of VEGF gene expression. Pharmacol Res 2008, 57:60-66.
    • (2008) Pharmacol Res , vol.57 , pp. 60-66
    • Amadio, M.1    Scapagnini, G.2    Lupo, G.3    Drago, F.4    Govoni, S.5    Pascale, A.6
  • 20
    • 38849117246 scopus 로고    scopus 로고
    • RNA-protein interactions and control of mRNA stability in neurons
    • Bolognani F., Perrone-Bizzozero N.I. RNA-protein interactions and control of mRNA stability in neurons. J Neurosci Res 2008, 86:481-489.
    • (2008) J Neurosci Res , vol.86 , pp. 481-489
    • Bolognani, F.1    Perrone-Bizzozero, N.I.2
  • 21
    • 0030044039 scopus 로고    scopus 로고
    • Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
    • Levy A.P., Levy N.S., Goldberg M.A. Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J Biol Chem 1996, 271:2746-2753.
    • (1996) J Biol Chem , vol.271 , pp. 2746-2753
    • Levy, A.P.1    Levy, N.S.2    Goldberg, M.A.3
  • 22
    • 0032513043 scopus 로고    scopus 로고
    • Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
    • Levy N.S., Chung S., Furneaux H., Levy A.P. Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J Biol Chem 1998, 273:6417-6423.
    • (1998) J Biol Chem , vol.273 , pp. 6417-6423
    • Levy, N.S.1    Chung, S.2    Furneaux, H.3    Levy, A.P.4
  • 23
    • 0036784268 scopus 로고    scopus 로고
    • Hu protein R-mediated posttranscriptional regulation of VEGF expression in rat gastrocnemius muscle
    • Tang K., Breen E.C., Wagner P.D. Hu protein R-mediated posttranscriptional regulation of VEGF expression in rat gastrocnemius muscle. Am J Physiol Heart Circ Physiol 2002, 283:H1497-1504.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Tang, K.1    Breen, E.C.2    Wagner, P.D.3
  • 24
    • 13544267632 scopus 로고    scopus 로고
    • New horizons for VEGF. Is there a role for nuclear localization?
    • Lejbkowicz F., Goldberg-Cohen I., Levy A.P. New horizons for VEGF. Is there a role for nuclear localization?. Acta Histochem 2005, 106:405-411.
    • (2005) Acta Histochem , vol.106 , pp. 405-411
    • Lejbkowicz, F.1    Goldberg-Cohen, I.2    Levy, A.P.3
  • 25
    • 0034060569 scopus 로고    scopus 로고
    • The protein kinase C beta-specific inhibitor LY379196 blocks TPA-induced monocytic differentiation of HL60 cells
    • Slosberg E.D., Yao Y., Xing F., Ikui A., Jirousek M.R., Weinstein I.B. The protein kinase C beta-specific inhibitor LY379196 blocks TPA-induced monocytic differentiation of HL60 cells. Mol Carcinog 2000, 27:166-176.
    • (2000) Mol Carcinog , vol.27 , pp. 166-176
    • Slosberg, E.D.1    Yao, Y.2    Xing, F.3    Ikui, A.4    Jirousek, M.R.5    Weinstein, I.B.6
  • 26
    • 0030598928 scopus 로고    scopus 로고
    • Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex
    • Pascale A., Fortino I., Govoni S., Trabucchi M., Wetsel W.C., Battaini F. Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex. Neurosci Lett 1996, 214:99-102.
    • (1996) Neurosci Lett , vol.214 , pp. 99-102
    • Pascale, A.1    Fortino, I.2    Govoni, S.3    Trabucchi, M.4    Wetsel, W.C.5    Battaini, F.6
  • 27
    • 0033578720 scopus 로고    scopus 로고
    • Coordinated movement of RACK1 with activated betaII PKC
    • Ron D., Jiang Z., Yao L., Vagts A., Diamond I., Gordon A. Coordinated movement of RACK1 with activated betaII PKC. J Biol Chem 1999, 274:27039-27046.
    • (1999) J Biol Chem , vol.274 , pp. 27039-27046
    • Ron, D.1    Jiang, Z.2    Yao, L.3    Vagts, A.4    Diamond, I.5    Gordon, A.6
  • 28
    • 0842342611 scopus 로고    scopus 로고
    • Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory
    • Pascale A., Gusev P.A., Amadio M., Dottorini T., Govoni S., Alkon D.L., et al. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. Proc Natl Acad Sci USA 2004, 101:1217-1222.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1217-1222
    • Pascale, A.1    Gusev, P.A.2    Amadio, M.3    Dottorini, T.4    Govoni, S.5    Alkon, D.L.6
  • 29
    • 24744459025 scopus 로고    scopus 로고
    • Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway
    • Pascale A., Amadio M., Scapagnini G. Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proc Natl Acad Sci USA 2005, 102:12065-12070.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12065-12070
    • Pascale, A.1    Amadio, M.2    Scapagnini, G.3
  • 30
    • 34447635434 scopus 로고    scopus 로고
    • Effect of insulin on acetylcholine-evoked amylase release and calcium mobilization in streptozotocin-induced diabetic rat pancreatic acinar cells
    • Patel R., Pariente J.A., Martinez M.A., Salido G.M., Singh J. Effect of insulin on acetylcholine-evoked amylase release and calcium mobilization in streptozotocin-induced diabetic rat pancreatic acinar cells. Ann N Y Acad Sci 2006, 1084:58-70.
    • (2006) Ann N Y Acad Sci , vol.1084 , pp. 58-70
    • Patel, R.1    Pariente, J.A.2    Martinez, M.A.3    Salido, G.M.4    Singh, J.5
  • 31
    • 13344293711 scopus 로고    scopus 로고
    • Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
    • Ishii H., Jirousek M.R., Koya D. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science 1996, 272:728-731.
    • (1996) Science , vol.272 , pp. 728-731
    • Ishii, H.1    Jirousek, M.R.2    Koya, D.3
  • 32
    • 8544251332 scopus 로고    scopus 로고
    • Protein kinase Cbeta II regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo
    • Liu Y., Su W., Thompson E.A., Leitges M., Murray N.R., Fields A.P. Protein kinase Cbeta II regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo. J Biol Chem 2004, 279:45556-45563.
    • (2004) J Biol Chem , vol.279 , pp. 45556-45563
    • Liu, Y.1    Su, W.2    Thompson, E.A.3    Leitges, M.4    Murray, N.R.5    Fields, A.P.6
  • 33
    • 77449100906 scopus 로고    scopus 로고
    • Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine
    • Kusari J., Zhou S.X., Padillo E., Clarke K.G., Gil D.W. Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine. Invest Ophthalmol Vis Sci 2010, 51:1044-1051.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1044-1051
    • Kusari, J.1    Zhou, S.X.2    Padillo, E.3    Clarke, K.G.4    Gil, D.W.5
  • 34
    • 1842855296 scopus 로고    scopus 로고
    • Blood-retinal barrier breakdown induced by activation of protein kinase C via vascular endothelial growth factor in streptozotocin-induced diabetic rats
    • Xu X., Zhu Q., Xia X., Zhang S., Gu Q., Luo D. Blood-retinal barrier breakdown induced by activation of protein kinase C via vascular endothelial growth factor in streptozotocin-induced diabetic rats. Curr Eye Res 2004, 28:251-256.
    • (2004) Curr Eye Res , vol.28 , pp. 251-256
    • Xu, X.1    Zhu, Q.2    Xia, X.3    Zhang, S.4    Gu, Q.5    Luo, D.6
  • 35
    • 56149110128 scopus 로고    scopus 로고
    • Amelioration of diabetes-associated abnormalities in the vitreous fluid by an inhibitor of albumin glycation
    • Cohen M.P., Hud E., Wu V.Y., Shearman C.W. Amelioration of diabetes-associated abnormalities in the vitreous fluid by an inhibitor of albumin glycation. Invest Ophthalmol Vis Sci 2008, 49:5089-5093.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 5089-5093
    • Cohen, M.P.1    Hud, E.2    Wu, V.Y.3    Shearman, C.W.4
  • 36
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group
    • DCCT Research Group
    • DCCT Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993, 329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 37
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: a unifying mechanism
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005, 54:1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 38
    • 0037154156 scopus 로고    scopus 로고
    • Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization
    • Suzuma K., Takahara N., Suzuma I. Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization. Proc Natl Acad Sci USA 2002, 99:721-726.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 721-726
    • Suzuma, K.1    Takahara, N.2    Suzuma, I.3
  • 39
    • 33845522286 scopus 로고    scopus 로고
    • Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice
    • Ohshiro Y., Ma R.C., Yasuda Y. Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice. Diabetes 2006, 55:3112-3120.
    • (2006) Diabetes , vol.55 , pp. 3112-3120
    • Ohshiro, Y.1    Ma, R.C.2    Yasuda, Y.3
  • 40
    • 23944474255 scopus 로고    scopus 로고
    • Expression of 14-3-3 zeta and interaction with protein kinase C in the rat retina in early diabetes
    • Kim Y.H., Kim Y.S., Kang S.S. Expression of 14-3-3 zeta and interaction with protein kinase C in the rat retina in early diabetes. Diabetologia 2005, 48:1411-1415.
    • (2005) Diabetologia , vol.48 , pp. 1411-1415
    • Kim, Y.H.1    Kim, Y.S.2    Kang, S.S.3
  • 41
    • 33846880290 scopus 로고    scopus 로고
    • N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats
    • Xia Z., Kuo K.H., Nagareddy P.R. N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats. Cardiovasc Res 2007, 73:770-782.
    • (2007) Cardiovasc Res , vol.73 , pp. 770-782
    • Xia, Z.1    Kuo, K.H.2    Nagareddy, P.R.3
  • 42
    • 41149157859 scopus 로고    scopus 로고
    • Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control
    • Langham R.G., Kelly D.J., Gow R.M., Zhang Y., Cox A.J., Qi W., et al. Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control. Diabetologia 2008, 51:668-674.
    • (2008) Diabetologia , vol.51 , pp. 668-674
    • Langham, R.G.1    Kelly, D.J.2    Gow, R.M.3    Zhang, Y.4    Cox, A.J.5    Qi, W.6
  • 43
    • 0036517850 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNFα suppression
    • Joussen A.M., Poulaki V., Mitsiades N., Kirchhof B., Koizumi K., Döhmen S., et al. Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNFα suppression. FASEB J 2002, 16:438-440.
    • (2002) FASEB J , vol.16 , pp. 438-440
    • Joussen, A.M.1    Poulaki, V.2    Mitsiades, N.3    Kirchhof, B.4    Koizumi, K.5    Döhmen, S.6
  • 44
    • 15644366961 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor
    • Aiello L.P., Bursell S.E., Clermont A., Duh E., Ishii H., Takagi C., et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes 1997, 46:1473-1480.
    • (1997) Diabetes , vol.46 , pp. 1473-1480
    • Aiello, L.P.1    Bursell, S.E.2    Clermont, A.3    Duh, E.4    Ishii, H.5    Takagi, C.6
  • 45
    • 44049099969 scopus 로고    scopus 로고
    • Protein kinase C beta inhibitors: a new therapeutic target for diabetic nephropathy and vascular complications
    • Budhiraja S., Singh J. Protein kinase C beta inhibitors: a new therapeutic target for diabetic nephropathy and vascular complications. Fundam Clin Pharmacol 2008, 22:231-240.
    • (2008) Fundam Clin Pharmacol , vol.22 , pp. 231-240
    • Budhiraja, S.1    Singh, J.2
  • 46
    • 43249114710 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis
    • Shibuya M. Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis. BMB Rep 2008, 41:278-286.
    • (2008) BMB Rep , vol.41 , pp. 278-286
    • Shibuya, M.1
  • 48
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: are there unifying principles?
    • Barreau C., Paillard L., Osborne H.B. AU-rich elements and associated factors: are there unifying principles?. Nucleic Acids Res 2006, 33:7138-7150.
    • (2006) Nucleic Acids Res , vol.33 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 49
    • 0034725054 scopus 로고    scopus 로고
    • Structural determinants for post-transcriptional stabilization of lactate dehydrogenase A mRNA by the protein kinase C signal pathway
    • Short S., Tian D., Short M.L., Jungmann R.A. Structural determinants for post-transcriptional stabilization of lactate dehydrogenase A mRNA by the protein kinase C signal pathway. J Biol Chem 2000, 275:12963-12969.
    • (2000) J Biol Chem , vol.275 , pp. 12963-12969
    • Short, S.1    Tian, D.2    Short, M.L.3    Jungmann, R.A.4
  • 50
    • 69049088805 scopus 로고    scopus 로고
    • Discovery of small peptides derived from embryonic lethal abnormal vision proteins structure showing RNA-stabilizing properties
    • Rossi D., Amadio M., Carnevale Baraglia A., Azzolina O., Ratti A., Govoni S., et al. Discovery of small peptides derived from embryonic lethal abnormal vision proteins structure showing RNA-stabilizing properties. J Med Chem 2009, 52:5017-5019.
    • (2009) J Med Chem , vol.52 , pp. 5017-5019
    • Rossi, D.1    Amadio, M.2    Carnevale Baraglia, A.3    Azzolina, O.4    Ratti, A.5    Govoni, S.6
  • 51
    • 33746233388 scopus 로고    scopus 로고
    • RNA-binding proteins: a lesson in repression
    • Wells D.G. RNA-binding proteins: a lesson in repression. J Neurosci 2006, 26:7135-7138.
    • (2006) J Neurosci , vol.26 , pp. 7135-7138
    • Wells, D.G.1
  • 52
    • 0033524475 scopus 로고    scopus 로고
    • Why is Hu where? Shuttling of early-response-gene messenger RNA subsets
    • Keene J.D. Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. Proc Natl Acad Sci USA 1999, 96:5-7.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5-7
    • Keene, J.D.1
  • 53
    • 0031939649 scopus 로고    scopus 로고
    • Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat
    • Hammes H.P., Lin J., Bretzel R.G., Brownlee M., Breier G. Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat. Diabetes 1998, 47:401-406.
    • (1998) Diabetes , vol.47 , pp. 401-406
    • Hammes, H.P.1    Lin, J.2    Bretzel, R.G.3    Brownlee, M.4    Breier, G.5
  • 54
    • 48849105733 scopus 로고    scopus 로고
    • Dexamethasone inhibits leukocyte accumulation and vascular permeability in retina of streptozotocin-induced diabetic rats via reducing vascular endothelial growth factor and intercellular adhesion molecule-1 expression
    • Wang K., Wang Y., Gao L., Li X., Li M., Guo J. Dexamethasone inhibits leukocyte accumulation and vascular permeability in retina of streptozotocin-induced diabetic rats via reducing vascular endothelial growth factor and intercellular adhesion molecule-1 expression. Biol Pharm Bull 2008, 31:1541-1546.
    • (2008) Biol Pharm Bull , vol.31 , pp. 1541-1546
    • Wang, K.1    Wang, Y.2    Gao, L.3    Li, X.4    Li, M.5    Guo, J.6
  • 56
    • 69349088835 scopus 로고    scopus 로고
    • Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response
    • Brucklacher R.M., Patel K.M., VanGuilder H.D., Bixler G.V., Barber A.J., Antonetti D.A., et al. Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics 2008, 1:26.
    • (2008) BMC Med Genomics , vol.1 , pp. 26
    • Brucklacher, R.M.1    Patel, K.M.2    VanGuilder, H.D.3    Bixler, G.V.4    Barber, A.J.5    Antonetti, D.A.6
  • 57
    • 27544481345 scopus 로고    scopus 로고
    • Efficacy of troxerutin on streptozotocin-induced rat model in the early stage of diabetic retinopathy
    • Chung H.K., Choi S.M., Ahn B.O., Kwak H.H., Kim J.H., Kim W.B. Efficacy of troxerutin on streptozotocin-induced rat model in the early stage of diabetic retinopathy. Arzneimittelforschung 2005, 55:573-580.
    • (2005) Arzneimittelforschung , vol.55 , pp. 573-580
    • Chung, H.K.1    Choi, S.M.2    Ahn, B.O.3    Kwak, H.H.4    Kim, J.H.5    Kim, W.B.6
  • 58
    • 57349135602 scopus 로고    scopus 로고
    • Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR
    • Amadio M., Scapagnini G., Laforenza U. Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR. Curr Pharm Des 2008, 14:2651-2658.
    • (2008) Curr Pharm Des , vol.14 , pp. 2651-2658
    • Amadio, M.1    Scapagnini, G.2    Laforenza, U.3
  • 60
    • 0141643318 scopus 로고    scopus 로고
    • Chronic ethanol exposure increases the binding of HuR to the TNFalpha 3'-untranslated region in macrophages
    • McMullen M.R., Cocuzzi E., Hatzoglou M., Nagy L.E. Chronic ethanol exposure increases the binding of HuR to the TNFalpha 3'-untranslated region in macrophages. J Biol Chem 2003, 278:38333-38341.
    • (2003) J Biol Chem , vol.278 , pp. 38333-38341
    • McMullen, M.R.1    Cocuzzi, E.2    Hatzoglou, M.3    Nagy, L.E.4
  • 62
    • 68149089755 scopus 로고    scopus 로고
    • Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM)
    • Ayalasomayajula S.P., Ashton P., Kompella U.B. Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM). J Ocul Pharmacol Ther 2009, 25:97-103.
    • (2009) J Ocul Pharmacol Ther , vol.25 , pp. 97-103
    • Ayalasomayajula, S.P.1    Ashton, P.2    Kompella, U.B.3
  • 63
    • 77749304040 scopus 로고    scopus 로고
    • Inhibition of protein kinase C delta attenuates blood-retinal barrier breakdown in diabetic retinopathy
    • Kim J.H., Kim J.H., Jun H.O., Yu Y.S., Kim K.W. Inhibition of protein kinase C delta attenuates blood-retinal barrier breakdown in diabetic retinopathy. Am J Pathol 2010, 176:1517-1524.
    • (2010) Am J Pathol , vol.176 , pp. 1517-1524
    • Kim, J.H.1    Kim, J.H.2    Jun, H.O.3    Yu, Y.S.4    Kim, K.W.5
  • 64
    • 0031737671 scopus 로고    scopus 로고
    • Vascular permeability in experimental diabetes associated with reduced endothelial occludin content
    • Antonetti D.A., Barber A.J., Khin S., Lieth E., Tarbell J.M., Gardner T.W. Vascular permeability in experimental diabetes associated with reduced endothelial occludin content. Diabetes 1998, 47:1953-1959.
    • (1998) Diabetes , vol.47 , pp. 1953-1959
    • Antonetti, D.A.1    Barber, A.J.2    Khin, S.3    Lieth, E.4    Tarbell, J.M.5    Gardner, T.W.6
  • 65
    • 18544377343 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation
    • Podar K., Tai Y.T., Lin B.K., Narsimhan R.P., Sattler M., Kijima T., et al. Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation. J Biol Chem 2002, 277:7875-7881.
    • (2002) J Biol Chem , vol.277 , pp. 7875-7881
    • Podar, K.1    Tai, Y.T.2    Lin, B.K.3    Narsimhan, R.P.4    Sattler, M.5    Kijima, T.6


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