Protein kinase Cβ1 and protein kinase Cβ2 activate p57 mitogen- activated protein kinase and block differentiation in colon carcinoma cells

Cell Growth and Differentiation

Volumn 7, Issue 5, 1996, Pages 587-594

  Sauma, Samir ^a   Zhongfa, Yan ^a   Ohno, Shigeo ^b   Friedman, Eileen ^a,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CALCIUM; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN BASIC PROTEIN; PHOSPHATIDYLSERINE; PROTEIN KINASE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ARTICLE; CARCINOMA CELL; CELL DIFFERENTIATION; CELL GROWTH; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH RATE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

ALTERNATIVE SPLICING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; CELL DIVISION; CLONE CELLS; COLONIC NEOPLASMS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 10244235304     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Boulton, T. G., Nye, S. H., Robbins, D. J., Ip. N. Y., Radziejewska, E., Morgenbesser, S. D., DePinho, R. A., Panaytatos, N., Cobb, M. H., and Yancopoulos, G. D. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell, 65: 663-675, 1991.
2. Robbins, D. J., Zhen, E., Cheng, M., Xu, S., Ebert, D., and Cobb, M. H. MAP kinases erk1 and erk2: pleiotropic enzymes in a ubiquitous signalling network. Adv. Cancer Res., 63: 93-116, 1994.
3. Anderson, N. G., Maller, J. L., Tonks, N. K., and Sturgill, T. W. Requirement for integration of signals from two distinct phosphorylation pathway for activation of MAP kinase. Nature (Lond.), 343: 651-653, 1990.
4. Seger, R., Ahn, N. G., Boulton, T. G., Yancopoulos, G. D., Panayotatos, N., Radziejewska, E., Ericson, L., Bratlein, R. L., Cobb, M. H., and Krebs, E. G. Microtubule-associated protein 2 kinases ERK1 and ERK2 undergo phosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. Proc. Natl. Acad. Sci. USA, 88: 6142-6146, 1991.
5. Rossomando, A. J., Payne, D. M., Weber, M. J., and Sturgill, T. W. Evidence that pp42, a major tyrosine kinase target protein, is a mitogen activated serine/threonine protein kinase. Proc. Natl. Acad. Sci. USA, 86: 6940-6943, 1989.
6. Lee, H., Ghose-Dastidar, J., Winawer, S., and Friedman, E. Signal transduction through ERK-like pp57 blocked in differentiated cells having low PKCβ activity. J. Biol. Chem., 268: 5255-5263, 1993.
7. Lee, H., Hsu, S., Winawer, S., and Friedman, E. Signal transduction through ERK-like pp57 blocked in differentiated colon carcinoma cells having low levels of c-src kinase. J. Biol. Chem., 268: 8181-8187, 1993.
8. Kubo, K., Ohno, S., and Suzuki, K. Primary structure of human protein kinase CβI and βII differ only in their C-terminal sequences. FEBS Lett., 223: 138-142, 1987.
9. Hafez, M. M., Infante, D., Winawer, S., and Friedman, E. TGF-β1 acts as an autocrine negative regulator in colon enterocytic differentiation but not in goblet cell maturation. Cell Growth & Differ., 1: 617-626, 1990.
10. Hafez, M. M., Hsu, S., Yan, Z., Winawer, S., and Friedman, E. Two roles for TGF-β1 in colon enterocytic differentiation. Cell Growth & Differ., 3: 753-762, 1992.
11. Pulverer, B. J., Kyriaskia, J. M., Avruch, J., Nikolakaki, E., and Woodgett, J. R. Phosphorylation of c-jun mediated by MAP kinases. Nature (Lond.), 353: 670-674, 1991.
12. Derijard, B., Hibi, M., Wu, I-H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. JNK1: a protein kinase stimulated by UV light and Ha-ras that binds and phosphorylates the c-jun activation domain. Cell, 76: 1025-1037, 1994.
13. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J. R. The stress-activated protein kinase subfamily of c-Jun kinases. Nature (Lond.), 369: 156-160, 1994.
14. Howe, I. R., Leevers, S. J., Gomez, N., Nakielny, S., Cohen, P., and Marshall, C. J. Activation of the MAP kinase pathway by the protein kinase raf. Cell, 71: 335-342, 1992.
15. Sozeri, O., Vollmer, K., Liyanage, M., Frith, D., Kour, G., Mark, G. E., II, and Stabel, S. Activation of the c-raf protein kinase by PKC phosphorylation. Oncogene, 7: 2259-2262, 1992.
16. Kolch, W., Heidecker, G., Kochs, G., Hummel, R., Vahidl, H., Mischak, H., Finkenzeller, G., Marme, D., and Rapp, U. R. PKCα activates Raf-1 by direct phosphorylation. Nature (Lond.), 364: 249-252, 1993.
17. Saxon, M. L., Zhao, X., and Black, J. D. Activation of PKC isozymes is associated with post-mitotic events in intestinal epithelial cells in situ. J. Cell Biol., 126: 747-763, 1994.
18. Gregorio, C. C., Kubo, R. T., Bankert, R. N., and Repasky, E. A. Translocation of spectrin and PKC to a cyloplasmic aggregate upon lymphocyte activation. Proc. Natl. Acad. Sci. USA, 89: 4947-4951, 1992.
19. Murray, N. R., Baumgardner, G. P., Burns, D. J., and Fields, A. P. PKC isozypes in human erythroleukemia K562 cell proliferation and differentiation. J. Biol. Chem., 268: 15847-15853, 1993.
20. Borner, C., Ueffig, M., Jaken, S., Parker, P. J., and Weinstein, I. B. Two closely related isoforms of PKC produce reciprocal effects on the growth of rat fibroblasts. J. Biol. Chem., 270: 78-86, 1995.
21. II PKC-selective nuclear membrane activation factor in human leukemic cells. J. Biol. Chem., 269: 21385-21390, 1994.
22. Choi, P. M., Tchou-Wong, K-M., and Weinstein, I. B. Overexpression of PKC in HT29 colon cancer cells causes growth inhibition and tumor suppression. Mol. Cell. Biol., 10: 4650-4657, 1990.
23. 2+-dependent kinases in human colon carcinomas. Cancer Res., 48: 3964-3972, 1988.
24. Kahl-Rainer, P., Karner-Hanusch, J., Weiss, W., and Marian, B. Five of six PKC isozymes present in normal mucosa show reduced protein levels during tumor development in the human colon. Carcinogenesis (Lond.), 15: 779-784, 1994.
25. Friedman, E. A., Higgins, P. J., Lipkin, M., Shinya, H., and Gelb, A. M. Tissue culture of human epithelial cells from benign colonic tumors. In Vitro (Rockville), 17: 632-644, 1981.
26. Friedman, E. Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and deoxycholic acid. Cancer Res., 41: 4588-4599, 1981.
27. Friedman, A., Isakkson, P., Rafter, J., Marian, D., Winawer, S., and Newmark, H. Fecal diglycerides as selective endogenous mitogens for premalignant and malignant human colonic epithelial cells. Cancer Res., 49: 544-548, 1989.
28. Hsu, S., Huang, F., Hafez, M., Winawer, S., and Friedman, E. Colon carcinoma cells switch their response to TGF-β1 with tumor progression. Cell Growth & Differ., 5: 267-275, 1994.