Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 5008-5021

  McDonagh, Brian ^a   Sakellariou, Giorgos K ^a   Smith, Neil T ^a   Brownridge, Philip ^b   Jackson, Malcolm J ^a  

^a William Henry Duncan Building   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

aconitase and sirtuin1; aging; Grp78; Redox proteomics; skeletal muscle metabolism

Indexed keywords

CHAPERONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTEINE; DJ 1 PROTEIN; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; PROTEOME; REGULATOR PROTEIN; ACONITATE HYDRATASE; FRUCTOSE BISPHOSPHATE ALDOLASE; MUSCLE PROTEIN;

AGING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; GASTROCNEMIUS MUSCLE; GLUCOSE METABOLISM; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OXIDATION; PROTEIN FUNCTION; PROTEOMICS; SARCOPENIA; SKELETAL MUSCLE; ACETYLATION; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSIOLOGY; PROCEDURES; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ACETYLATION; ACONITATE HYDRATASE; AGING; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CYSTEINE; FRUCTOSE-BISPHOSPHATE ALDOLASE; MALE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84908895052     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5006394     Document Type: Article

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