Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor/Ca2+ release channel (RyR1): Sites and nature of oxidative modification

Journal of Biological Chemistry

Volumn 288, Issue 32, 2013, Pages 22961-22971

  Sun, Qi An ^a   Wang, Benlian ^a   Miyagi, Masaru ^a   Hess, Douglas T ^a   Stamler, Jonathan S ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYS RESIDUES; OXIDATIVE MODIFICATION; OXYGEN TENSION; REDOX REGULATION; RYANODINE RECEPTORS; S-NITROSYLATION; SKELETAL MUSCLE;

MASS SPECTROMETRY; OXYGEN;

MUSCLE;

1,4 DIHYDROPYRIDINE RECEPTOR; CALCIUM CHANNEL L TYPE; CYSTINE; DISULFIDE; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 12; GLUTATHIONYLATED NORSULFENAMIDE; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; RYANODINE RECEPTOR 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CENTRAL CORE DISEASE; CONTROLLED STUDY; CYTOPLASM; ISOTOPE LABELING; MALIGNANT HYPERTHERMIA; MASS SPECTROMETRY; MEMBRANE VESICLE; NITROSYLATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; RABBIT; REGULATORY MECHANISM; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

DISULFIDE; REACTIVE OXYGEN SPECIES (ROS); REDOX REGULATION; REDOX SIGNALING; RYANODINE RECEPTOR; S-OXIDATION; SKELETAL MUSCLE;

ANIMALS; CALCIUM; HYDROGEN PEROXIDE; MUSCLE PROTEINS; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXYGEN; PROTEIN STRUCTURE, TERTIARY; RABBITS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 84881399508     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.480228     Document Type: Article

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