Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 5185-5197

  Sjoelund, Virginie ^a   Smelkinson, Margery ^a   Nita Lazar, Aleksandra ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

innate immunity; macrophage; phosphoproteomics; SILAC; TLR2; TLR4; TLR7; toll like receptors

Indexed keywords

AMINO ACID; CALNEXIN; CYCLIN DEPENDENT KINASE 18; CYTOSKELETON PROTEIN; FOCAL ADHESION KINASE; GUANOSINE TRIPHOSPHATASE; JANUS KINASE; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PHOSPHOLIPASE C; PHOSPHOPEPTIDE; PROTEIN; REACTIVE OXYGEN METABOLITE; RESIQUIMOD; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7; STABLE ISOTOPE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHOPROTEIN; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CHROMATOGRAPHY; CYTOSKELETON; ENDOCYTOSIS; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PHOSPHORYLATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; STRONG CATION EXCHANGE CHROMATOGRAPHY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; MACROPHAGE ACTIVATION; METABOLISM; PHOSPHORYLATION; PROCEDURES; PROTEOMICS;

ANIMALS; CELLS, CULTURED; IMIDAZOLES; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; PHAGOCYTOSIS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEOMICS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 84908891783     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5002466     Document Type: Article

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