Quantitative proteomic approach to understand metabolic adaptation in non-small cell lung cancer

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 4695-4704

  Martín Bernabé, Alfonso ^a,b,c,d   Cortés, Roldán ^a   Lehmann, Sylvia G ^b,c,d   Seve, Michel ^b,c,d   Cascante, Marta ^a   Bourgoin Voillard, Sandrine ^b,c,d,e  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTE FOR ADVANCED BIOSCIENCES   (France)

^c INSERM   (France)

^d GRENOBLE UNIVERSITY HOSPITAL   (France)

^e UNIV GRENOBLE ALPES   (France)

Author keywords

cancer metabolism; drug resistance; iTRAQ quantitative proteomic approach; NSCLC

Indexed keywords

BIOLOGICAL MARKER; ENZYME; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; K RAS PROTEIN; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; LACTATE DEHYDROGENASE B; PENTOSE PHOSPHATE; PHOSPHOGLUCONATE DEHYDROGENASE; PROTEIN; PYRUVATE KINASE; PYRUVATE KINASE M2; TRANSKETOLASE; UNCLASSIFIED DRUG; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

A549 CELL LINE; ANALYTIC METHOD; ARTICLE; BRONCHUS; CANCER CELL; CONTROLLED STUDY; ENZYME ACTIVITY; FRACTIONATION; GLYCOLYSIS; HUMAN; HUMAN CELL; ISOELECTRIC FOCUSING; ITRAQ; LUNG CANCER CELL LINE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NON SMALL CELL LUNG CANCER; NUCLEOTIDE SEQUENCE; OFFGEL ISOELECTROFOCUSING; PENTOSE PHOSPHATE CYCLE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN TARGETING; PROTEOMICS; QUANTITATIVE ANALYSIS; RECEPTOR UPREGULATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVERSED PHASE NANOLIQUID CHROMATOGRAPHY; SCREENING TEST; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING; CARCINOMA, NON-SMALL-CELL LUNG; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SCREENING; LIQUID CHROMATOGRAPHY; METABOLISM; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE;

BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; PENTOSE PHOSPHATE PATHWAY; PROTEOMICS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 84908884096     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500327v     Document Type: Article

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