LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis

Breast Cancer Research and Treatment

Volumn 131, Issue 3, 2012, Pages 791-800

  Wang, Zhi Yu ^a   Loo, Tjing Yung ^b   Shen, Jian Gang ^a   Wang, Neng ^a   Wang, Dong Mei ^c   Yang, De Po ^c   Mo, Sui Lin ^c   Guan, Xin Yuan ^d   Chen, Jian Ping ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIMED Medical Institute   (Hong Kong)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Breast cancer; LDH A; Mitochondrion; Oxidative stress

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE ISOENZYME 5; PROGESTERONE RECEPTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CARCINOGENESIS; CARCINOGENICITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GENE SEQUENCE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MENOPAUSE; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; ISOENZYMES; L-LACTATE DEHYDROGENASE; MICE; MITOCHONDRIA; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84856213516     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1466-6     Document Type: Article

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