Human lung cancer antigens recognized by autologous antibodies: Definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3

Cancer Research

Volumn 58, Issue 5, 1998, Pages 1034-1041

  Güre, Ali O ^a   Altorki, Nasser K ^b   Stockert, Elisabeth ^a   Scanlan, Matthew J ^a   Old, Lloyd J ^a   Chen, Yao Tseng ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXIN; COMPLEMENTARY DNA; FRUCTOSE BISPHOSPHATE ALDOLASE; RECOMBINANT DNA; RNA; TUMOR ANTIGEN;

AMINO ACID SEQUENCE; ARTICLE; CHROMOSOME 3P; CONTROLLED STUDY; DNA SEQUENCE; GENE LOCUS; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMORAL IMMUNITY; LUNG CANCER; LUNG CARCINOGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM; SOUTHERN BLOTTING; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 3; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENES, TUMOR SUPPRESSOR; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

EID: 2642712493     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Boon, T., and van der Bruggen, P. Human tumor antigens recognized by T lymphocytes. J. Exp. Med., 183: 725-729, 1996.
2. Rosenberg, S. A. Development of cancer immunotherapies based on identification of the genes encoding cancer regression antigens. J. Natl. Cancer Inst. (Bethesda), 88: 1635-1644, 1996.
3. Sahin, U., Türeci, O., Schmitt, H., Cochlovius, B., Johannes, T., Schmits, R., Stenner, F., Luo, G., Schobert, I., and Pfreundschuh, M. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc. Natl. Acad. Sci. USA, 92: 11810-11813, 1995.
4. Chen, Y. T., Scanlan, M. J., Sahin, U., Türeci, O., Güre, A. O., Tsang, S., Williamson, B., Stockert, E., Pfreundschuh, M., and Old, L. J. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc. Natl. Acad. Sci. USA, 94: 1914-1918, 1997.
5. Robbins, P. F., el-Gamil, M., Kawakami, Y., Stevens, E., Yannelli, J. R., and Rosenberg, S. A. Recognition of tyrosinase by tumor-infiltrating lymphocytes from a patient responding to immunotherapy. Cancer Res., 54: 3124-3126, 1994.
6. van der Bruggen, P., Traversari, C., Chomez, P., Lurquin, C., De Plaen, E., Van den Eynde, B., Knuth, A., and Boon, T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (Washington DC), 254: 1643-1647, 1991.
7. Brichard, V., Van Pel, A., Wolfel, T., Wolfel, C., De Plaen, E., Lethe, B., Coulie, P., and Boon, T. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 178: 489-495, 1993.
8. Güre, A. O., Türeci, O., Sahin, U., Tsang, S., Scanlan, M. J., Jager, E., Knuth, A., Pfreundschuh, M., Old, L. J., and Chen, Y. T. SSX: a multigene family with several members actively transcribed in normal testis and cancer. Int. J. Cancer, 72: 965-971, 1997.
9. Kok, K., Naylor, S. L., and Buys, C. H. Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv. Cancer Res., 71: 27-92, 1997.
10. Dracopoli, C. D., Haines, J. L., Korf, B. R., Moir, D. T., Morton, C. C., Seidman, J. G., and Smith, D. R. (eds.). Current Protocols in Human Genetics. Chapter 7.4. New York: John Wiley & Sons, Inc., 1997.
11. Kurdi-Haidar, B., Aebi, S., Heath, D., Enns, R. E., Naredi, P., Hom, D. K., and Howell, S. B. Isolation of the ATP-binding human homolog of the arsA component of the bacterial arsenite transporter. Genomics, 36: 486-491, 1996.
12. Misaki, Y., Pruijn, G. J., van der Kemp, A. W., and van Venrooij, W. J. The 56K autoantigen is identical to human annexin XI. J. Biol. Chem., 269: 4240-4246, 1994.
13. Misaki, Y., Van Venrooij, W. J., and Pruijn, G. J. Prevalence and characteristics of anti-56K/annexin XI autoantibodies in systemic autoimmune diseases. J. Rheumatol., 22: 97-102, 1995.
14. Refaeli, Y., Levy, D. N., and Weiner, D. B. The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product. Proc. Natl. Acad. Sci. USA, 92: 3621-3625, 1995.
15. Wei, M. H., Latif, F., Bader, S., Kashuba, V., Chen, J. Y., Duh, F. M., Sekido, Y., Lee, C. C., Geil, L., Kuzmin, I., Zabarovsky, E., Klein, G., Zbar, B., Minna, J. D., and Lerman, M. I. Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG. Cancer Res., 56: 1487-1492, 1996.
16. Coleman, M. P., Ambrose, H. J., Carrel, L., Nemeth, A. H., Willard, H. F., and Davies, K. E. A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status. Genomics, 31: 135-138, 1996.
17. Inoue, A., Takahashi, K. P., Kimura, M., Watanabe, T., and Morisawa, S. Molecular cloning of a RNA binding protein, S1-1. Nucleic Acids Res., 24: 2990-2997, 1996.
18. Witte, M. M., and Scott, R. E. The proliferation potential protein-related (P2P-R) gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rb1 binding shows repressed expression during terminal differentiation. Proc. Natl. Acad. Sci. USA, 94: 1212-1217, 1997.
19. Wilson, R., Ainscough, R., Anderson, K., Baynes, C., Berks, M., Bonfield, J., Burton, J., Connell, M., Copsey, T., Cooper, J., et al. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature (Lond.), 368: 32-38, 1994.
20. Seraphin, B., Simon, M., Boulet, A., and Faye, G. Mitochondrial splicing requires a protein from a novel helicase family. Nature (Lond.), 337: 84-87, 1989.
21. Takagaki, Y., MacDonald, C. C., Shenk, T., and Manley, J. L. The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proc. Natl. Acad. Sci. USA, 89: 1403-1407, 1992.
22. Brass, N., Heckel, D., Şahin, U., Pfreundschuh, M., Sybrecht, G. W., and Meese, E. Translation initiation factor eIF-4γ is encoded by an amplified gene and induces an immune response in squamous cell lung carcinoma. Hum. Mol. Genet., 6: 33-39, 1997.
23. Schapira, F. Isozymes and cancer. Adv. Cancer Res., 18: 77-153, 1973.
24. Ojika, T., Imaizumi, M., Abe, T., and Kato, K. Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer. Cancer (Phila.), 67: 2153-2158, 1991.
25. Asaka, M., Kimura, T., Meguro, T., Kato, M., Kudo, M., Miyazaki, T., and Alpert, E. Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases. J Clin. Lab. Anal., 8: 144-148, 1994.
26. Naylor, S. L., Johnson, B. E., Minna, J. D., and Sakaguchi, A. Y. Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. Nature (Lond.), 329: 451-454, 1987.
27. Yokota, J., Wada, M., Shimosato, Y., Terada, M., and Sugimura, T. Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Proc. Natl. Acad. Sci. USA. 84: 9252-9256, 1987.
28. Killary, A. M., Wolf, M. E., Giambernardi, T. A., and Naylor, S. L. Definition of a tumor suppressor locus within human chromosome 3p21-p22. Proc. Natl. Acad. Sci. USA, 89: 10877-10881, 1992.
29. Daly, M. C., Xiang, R. H., Buchhagen, D., Hensel, C. H., Garcia, D. K., Killary, A. M., Minna, J. D., and Naylor, S. L. A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity. Oncogene, 8: 1721-1729, 1993.
30. Kok, K., van den Berg, A., Veldhuis, P. M., van der Veen, A. Y., Franke, M., Schoenmakers, E. F., Hulsbeek, M. M., van der Hout, A. H., de Leij, L., van de Ven, W., and Buys, C. H. A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes. Cancer Res., 54: 4183-4187, 1994.
31. Roche, J., Boldog, F., Robinson, M., Robinson, L., Varella-Garcia, M., Swanton, M., Waggoner, B., Fishel, R., Franklin, W., Gemmill, R., and Drabkin, H. Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin. Oncogene, 12: 1289-1297, 1996.
32. Todd, M. C., Xiang, R. H., Garcia, D. K., Kerbacher, K. E., Moore, S. L., Hensel, C. H., Liu, P., Siciliano, M. J., Kok, K., van den Berg, A., Veldhuis, P., Buys, C. H., Killary, A. M., and Naylor, S. L. An 80-kb P1 clone from chromosome 3p21.3 suppresses tumor growth in vivo. Oncogene, 13: 2387-2396, 1996.
33. Baker, S. J., Preisinger, A. C., Jessup, J. M., Paraskeva, C., Markowitz, S., Willson, J. K., Hamilton, S., and Vogelstein, B. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res., 50: 7717-7722, 1990.
34. Bennett, W. P., Hollstein, M. C., He, A., Zhu, S. M., Resau, J. H., Trump, B. F., Metcalf, R. A., Welsh, J. A., Midgley, C., Lane, D. P., and Harris, C. C. Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer. Oncogene, 6: 1779-1784, 1991.
35. Takahashi, T., D'Amico, D., Chiba, I., Buchhagen, D. L., and Minna, J. D. Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer. J. Clin. Invest., 86: 363-369, 1990.
36. Bodner, S. M., Minna, J. D., Jensen, S. M., D'Amico, D., Carbone, D., Mitsudomi, T., Fedorko, J., Buchhagen, D. L., Nau, M. M., Gazdar, A. F., and Linnoila, R. I. Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation. Oncogene, 7: 743-749, 1992.
37. Mashal, R. D., and Sklar, J. Practical methods of mutation detection. Curr. Opin. Genet. Dev., 6: 275-280, 1996.
38. Yokoyama, N., Hayashi, N., Seki, T., Pante, N., Ohba, T., Nishii, K., Kuma, K., Hayashida, T., Miyata, T., Aebi, U., Fukui, M., and Nishimoto, T. A giant nucleopore protein that binds Ran/TC4. Nature (Lond.), 376: 184-188, 1995.