Role of continuous high thoracic epidural anesthesia in hippocampal apoptosis after global cerebral ischemia in rats

Cellular Physiology and Biochemistry

Volumn 34, Issue 4, 2014, Pages 1227-1240

  Li, Xuan ^a   Huo, Xing ^a   Zhang, Chongyou ^a   Ma, Xinyu ^a,b   Han, Fei ^a   Wang, Guonian ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Chifeng University   (China)

Author keywords

Apoptosis; Cerebral ischemia; Global; High thoracic epidural anesthesia (HTEA); Poly (ADP ribose) polymerase (PARP); Rats

Indexed keywords

BUPIVACAINE; MALONALDEHYDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; LOCAL ANESTHETIC AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EPIDURAL DRUG ADMINISTRATION; EPIDURAL SPACE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MORTALITY; NERVE CELL; NICK END LABELING; NISSL SUBSTANCE; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION; SYMPATHETIC BLOCKING; THORAX EPIDURAL ANESTHESIA; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN CIRCULATION; DRUG EFFECTS; EPIDURAL ANESTHESIA; GENETICS; METABOLISM; OXIDATIVE STRESS; PROCEDURES; REPERFUSION INJURY; WISTAR RAT;

ANESTHESIA, EPIDURAL; ANESTHETICS, LOCAL; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; BUPIVACAINE; CEREBROVASCULAR CIRCULATION; DOWN-REGULATION; HIPPOCAMPUS; MALE; MALONDIALDEHYDE; NEURONS; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 84908655185     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366334     Document Type: Article

References (53)

1. Liang HW, Qiu SF, Shen J, Sun LN, Wang JY, Bruce IC, Xia Q: Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus. Neurosci Lett 2008;438:116-120.
2. Sugawara T, Fujimura M, Noshita N, Kim GW, Saito A, Hayashi T, Narasimhan P, Maier CM, Chan PH: Neuronal death/survival signaling pathways in cerebral ischemia. NeuroRX 2004;1:17-25.
3. Nitatori T, Sato N, Waguri S, Karasawa Y, Araki H, Shibanai K, Kominami E, Uchiyama Y: Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci 1995;15:1001-1011.
4. Takahashi K, Pieper AA, Croul SE, Zhang J, Snyder SH, Greenberg JH: Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia. Brain Res 1999;829:46-54.
5. Lindahl T, Satoh MS, Poirier GG, Klungland A: Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem Sci 1995;20:405-411.
6. Saito A, Maier CM, Narasimhan P, Nishi T, Song YS, Yu F, Liu J, Lee YS, Nito C, Kamada H, Dodd RL, Hsieh LB, Hassid B, Kim EE, Gonzalez M, Chan PH: Oxidative stress and neuronal death/survival signaling in cerebral ischemia. Mol Neurobiol 2005;31:105-116.
7. Bedirli N, Akyurek N, Kurtipek O, Kavutcu M, Kartal S, Bayraktar AC: Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. Anesth Analg 2011;113:1226-1232.
8. Miller CL, Lampard DG, Alexander K, Brown WA: Local cerebral blood flow following transient cerebral ischemia. I. Onset of impaired reperfusion within the first hour following global ischemia. Stroke 1980;11:534-541.
9. Hauck EF, Apostel S, Hoffmann JF, Heimann A, Kempski O: Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. J Cereb Blood Flow Metab 2004;24:383-391.
10. Gupta MM, Bithal PK, Dash HH, Chaturvedi A, Mahajan RP: Effects of stellate ganglion block on cerebral haemodynamics as assessed by transcranial Doppler ultrasonography. Br J Anaesth 2005;95:669-673.
11. Westerhaus MJ, Loewy AD: Central representation of the sympathetic nervous system in the cerebral cortex. Brain Res 2001;903:117-127.
12. Murata Y, Shibata H, Chiba T: A correlative quantitative study comparing the nerve fibers in the cervical sympathetic trunk and the locus of the somata from which they originate in the rat. J Auton Nerv Syst 1982;6:323-333.
13. Higa K, Hori K, Harasawa I, Hirata K, Dan K: High thoracic epidural block relieves acute herpetic pain involving the trigeminal and cervical regions: comparison with effects of stellate ganglion block. Reg Anesth Pain Med 1998;23:25-29.
14. Kim EM, Yoon KB, Lee JH, Yoon DM, Kim do H: The effect of oxygen administration on regional cerebral oxygen saturation after stellate ganglion block on the non-blocked side. Pain Physician 2013;16:117-124.
15. Lang O, Svoboda L, Balon HR: Effect of sympathetic blockade on cerebral perfusion demonstrated on Tc-99m HMPAO SPECT. J Neurol 2002;249:108-109.
16. Chun-jing H, Shan O, Guo-dong L, Hao-xiong N, Yi-ran L, Ya-ping F: Effect of cervical sympathetic block on cerebral vasospasm after subarachnoid hemorrhage in rabbits. Acta Cir Bras 2013;28:89-93.
17. Treggiari MM, Romand JA, Martin JB, Reverdin A, Rufenacht DA, de Tribolet N: Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhage. Stroke 2003;34:961-967.
18. Kang CK, Oh ST, Chung RK, Lee H, Park CA, Kim YB, Yoo JH, Kim DY, Cho ZH: Effect of stellate ganglion block on the cerebrovascular system: magnetic resonance angiography study. Anesthesiology 2010;113:936-944.
19. ter Laan M, van Dijk JM, Elting JW, Staal MJ, Absalom AR: Sympathetic regulation of cerebral blood flow in humans: a review. Br J Anaesth 2013;111:361-367.
20. Sandor P: Nervous control of the cerebrovascular system: doubts and facts. Neurochem Int 1999;35:237-259.
21. Xiong L, Wang Y, Wang Q, Zhou Q: Cervical sympathetic trunk transection affects inducible nitric oxide synthase expression in rat hippocampus following focal cerebral ischemia/reperfusion injury. Neural Regen Res 2008;3:1084-1087.
22. Kozian A, Schilling T, Hachenberg T: Non-analgetic effects of thoracic epidural anaesthesia. Curr Opin Anesthesiol 2005;18:29-34.
23. Guo Z, Wang JP: Blockade of spinal nerves attenuates myocardial apoptosis in acute myocardial ischaemia/ infarction in rats. Eur J Anaesthesiol 2010;27:146-152.
24. Pulsinelli WA, Brierley JB: A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 1979;10:267-272.
25. Yoshizumi H, Fujibayashi Y, Kikuchi H: A new approach to the integrity of dual blood-brain barrier functions of global ischemic rats. Barrier and carrier functions. Stroke 1993;24:279-284.
26. Ostrowski RP, Colohan AR, Zhang JH: Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab 2005;25:554-571.
27. Martinez G, Musumeci G, Loreto C, Carnazza ML: Immunohistochemical changes in vulnerable rat brain regions after reversible global brain ischaemia. J Mol Histol 2007;38:295-302.
28. Cheng O, Ostrowski RP, Wu B, Liu W, Chen C, Zhang JH: Cyclooxygenase-2 mediates hyperbaric oxygen preconditioning in the rat model of transient global cerebral ischemia. Stroke 2011;42:484-490.
29. Duan YL, Wang SY, Zeng QW, Su DS, Li W, Wang XR, Zhao Z: Astroglial reaction to delta opioid peptide [D-Ala2, D-Leu5] enkephalin confers neuroprotection against global ischemia in the adult rat hippocampus. Neuroscience 2011;192:81-90.
30. Geocadin R, Ghodadra R, Kimura T, Lei H, Sherman D, Hanley D, Thakor N: A novel quantitative EEG injury measure of global cerebral ischemia. Clin Neurophysiol 2000;111:1779-1787.
31. Ji Q, Hui K, Zhang L, Sun X, Li W, Duan M: The effect of hydrogen-rich saline on the brain of rats with transient ischemia. J Surg Res 2011;168:e95-101.
32. Lee WY, Park CJ, Shin TJ, Yum KW, Yoon TG, Seo KS, Kim HJ: Only tetracaine and not other local anaesthetics induce apoptosis in rat cortical astrocytes. Br J Anaesth 2009;103:719-725.
33. Takenami T, Yagishita S, Nara Y, Tsai YH, Hiruma H, Kawakami T, Hoka S: Spinal procaine is less neurotoxic than mepivacaine, prilocaine and bupivacaine in rats. Reg Anesth Pain Med 2009;34:189-195.
34. Freise H, Lauer S, Konietzny E, Hinkelmann J, Minin E, Van Aken HK, Lerch MM, Sielenkaemper AW, Fischer LG: Hepatic effects of thoracic epidural analgesia in experimental severe acute pancreatitis. Anesthesiology 2009;111:1249-1256.
35. Freise H, Anthonsen S, Fischer LG, Van Aken HK, Sielenkamper AW: Continuous thoracic epidural anesthesia induces segmental sympathetic block in the awake rat. Anesth Analg 2005;100:255-262.
36. Tuor UI: Local distribution of the effects of sympathetic stimulation on cerebral blood flow in the rat. Brain Res 1990;529:224-231.
37. Shu CC, Hoffman WE, Thomas C, Albrecht RF: Sympathetic activity enhances glucose-related ischemic injury in the rat. Anesthesiology 1993;78:1120-1125.
38. Werner C, Hoffman WE, Thomas C, Miletich DJ, Albrecht RF: Ganglionic blockade improves neurologic outcome from incomplete ischemia in rats: partial reversal by exogenous catecholamines. Anesthesiology 1990;73:923-929.
39. Schultz JA, Hoffman WE, Albrecht RF: Sympathetic stimulation with physostigmine worsens outcome from incomplete brain ischemia in rats. Anesthesiology 1993;79:114-121.
40. Jeng JS, Yip PK, Huang SJ, Kao MC: Changes in hemodynamics of the carotid and middle cerebral arteries before and after endoscopic sympathectomy in patients with palmar hyperhidrosis: preliminary results. J Neurosurg 1999;90:463-467.
41. Murakawa K, Noma K, Ishida K, Matsuda M, Terashita K, Maeda S, Izumi R: Circulatory effects of stellate ganglion block and high thoracic epidural block. Masui 1994;43:998-1003. (in Japanese)
42. Soehle M, Heimann A, Kempski O: Postischemic application of lipid peroxidation inhibitor U-101033E reduces neuronal damage after global cerebral ischemia in rats. Stroke 1998;29:1240-1246; discussion 1246-1247.
43. Goplerud JM, Wagerle LC, Delivoria-Papadopoulos M: Sympathetic nerve modulation of regional cerebral blood flow during asphyxia in newborn piglets. Am J Physiol 1991;260:H1575-1580.
44. Nagao T, Sadoshima S, Ishitsuka T, Kusuda K, Shiokawa O, Ibayashi S, Fujishima M: Effects of acute superior cervical ganglionectomy on cerebral blood flow and metabolism in stroke-prone spontaneously hypertensive rats subjected to cerebral ischaemia. Clin Exp Pharmacol Physiol 1992;19:489-493.
45. Xu Y, Liachenko SM, Tang P, Chan PH: Faster recovery of cerebral perfusion in SOD1-overexpressed rats after cardiac arrest and resuscitation. Stroke 2009;40:2512-2518.
46. Wang Y, Liu X, Zhang D, Chen J, Liu S, Berk M: The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction. BMC Med 2013;11:32-32.
47. Smrcka M, Horky M, Otevrel F, Kuchtickova S, Kotala V, Muzik J: The onset of apoptosis of neurons induced by ischemia-reperfusion injury is delayed by transient period of hypertension in rats. Physiol Res 2003;52:117-122.
48. Satoh M, Date I, Nakajima M, Takahashi K, Iseda K, Tamiya T, Ohmoto T, Ninomiya Y, Asari S: Inhibition of poly(ADP-ribose) polymerase attenuates cerebral vasospasm after subarachnoid hemorrhage in rabbits. Stroke 2001;32:225-231.
49. Plaschke K, Kopitz J, Weigand Ma, Martin E, Bardenheuer HJ: The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia. Neurosci Lett 2000;284:109-112.
50. Huo X, Li ZX, Jiang LH, Wang HM, Qu RH, Wang GN: Effects of high thoracic epidural anesthesia on cerebral ischemia-reperfusion injury in rats. Chin J Anesthesiol 2006;26:710-713. (in Chinese)
51. Kuroda Y, Sakabe T, Nakakimura K, Oshita S, Maekawa T, Ishikawa T, Takeshita H: Epidural bupivacaine suppresses local glucose utilization in the spinal cord and brain of rats. Anesthesiology 1990;73:944-950.
52. Marganella C, Bruno V, Matrisciano F, Reale C, Nicoletti F, Melchiorri D: Comparative effects of levobupivacaine and racemic bupivacaine on excitotoxic neuronal death in culture and N-methyl-D-aspartate-induced seizures in mice. Eur J Pharmacol 2005;518:111-115.
53. Lee JR, Han SM, Leem JG, Hwang SJ: Effects of intrathecal bupivacaine in conjunction with hypothermia on neuronal protection against transient spinal cord ischemia in rats. Acta Anaesthesiol Scand 2007;51:60-67.