Blockade of spinal nerves attenuates myocardial apoptosis in acute myocardial ischaemia/infarction in rats

European Journal of Anaesthesiology

Volumn 27, Issue 2, 2010, Pages 146-152

  Guoa, Zheng ^a   Wang, Jin Ping ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspases; Coronary circulation; Epidural; Myocardial infarction; Naesthesia

Indexed keywords

CASPASE; CASPASE 3; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; ROPIVACAINE; AMIDE; LOCAL ANESTHETIC AGENT;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; EPIDURAL ANESTHESIA; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; NERVE BLOCK; NERVE CELL; NICK END LABELING; NONHUMAN; RAT; SHAM PROCEDURE; SPINAL NERVE; ST SEGMENT; ANIMAL; DISEASE MODEL; DRUG EFFECT; MALE; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

AMIDES; ANESTHESIA, EPIDURAL; ANESTHETICS, LOCAL; ANIMALS; APOPTOSIS; CASPASE 3; DISEASE MODELS, ANIMAL; IN SITU NICK-END LABELING; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; NERVE BLOCK; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 77950355543     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e32832e08f8     Document Type: Article

References (24)

1. Haunstetter A, Izumo S. Apoptosis. Basic mechanisms and implications for cardiovascular disease. Circ Res 1998; 82:1111-1129.
2. Haunstetter A, Izumo S. Toward antiapoptosis as a new treatment modality. Circ Res 2000; 86:371-376.
3. Schömig A. Catecholamines in myocardial ischemia: Systemic and cardiac release. Circulation 1990; 82:II-13-II-22.
4. Franco-Cereceda A. Calcitonin gene-related peptide and tachykinins in relation to local sensory control of cardiac contractility and coronary vascular tone. Acta Physiol Scand Suppl 1988; 569:1-63.
5. Franco-Cereceda A, Saria A, Lundberg JM. Differential release of calcitonin gene-related peptide and neuropeptide Y from the isolated heart by capsaicin, ischaemia, nicotine, bradykinin and ouabain. Acta Physiol Scand 1989; 135:173-187.
6. Milner P, Ralevic V, Hopwood AM, et al. Ultrastructural localisation of substance P and choline acetyltransferase in endothelial cells of rat coronary artery and release of substance P and acetylcholine during hypoxia. Experientia 1989; 45:121-125.
7. Mair J, Lechleitner P, Langle T, et al. Plasma CGRP in acute myocardial infarction. Lancet 1990; 335:168.
8. Zhang JW, Guo Z. Changes in substance P in myocardial and dorsal root gangion following coronary artery occlusion in rats. Chin Crit Care Med 2006; 18:201-205.
9. Guo Z, Niu YL, Zhang JW, Yao TP. Coronary artery occlusion alters expression of substance P and its mRNA in spinal dorsal horn in rats. Neuroscience 2007; 145:669-675.
10. Adams KFJR. Pathophysiologic role of the rennin-angiotensin- aldosterone and sympathetic nervous systems in heart failure. Am J Health Syst Pharm 2004; 61 (Suppl 2):S4-S13.
11. Fliss H, Gattinger D. Apoptosis in ischemic and reperfused rat myocardium. Circ Res 1996; 79:949-956.
12. Saraste A, Pulkki K, Kallojoki M, et al. Apoptosis in human acute myocardial infarction. Circulation 1997; 95:320-323.
13. Kajstura J, Cheng W, Reiss K, et al. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 1996; 74:86-107.
14. Bialik S, Geenan DL, Sasson IE, et al. Myocardial apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Invest 1997; 100:1363-1372.
15. Davis RF, DeBoer LWV, Maroko PR. Thoracic epidural anesthesia reduces myocardial infarct size after coronary artery occlusion in dogs. Anesth Analg 1986; 65:711-717.
16. Malliani A. The conceptualisation of cardiac pain as a nonspecific and unreliable alarm system. In: Gebhart GF, editor. Visceral pain, progress in pain research and management. Seattle, WA: IASP Press; 1995. pp. 63- 74.
17. Dart AM, Du XJ. Unexpected drug effects on autonomic function during myocardial ischaemia. Cardiovasc Res 1993; 27:906-914.
18. Mann DL, Kent RL, Parsons B, Cooper G. Adrenergic effects on the biology of the adult mammalian cardiocyte. Circulation 1992; 85:790-804.
19. Communal C, Singh K, David R, Colucci WS. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the ß-adrenergic pathway. Circulation 1998; 98:1329-1334.
20. Blomberg S, Emanuelsson H, Ricksten SE. Thoracic epidural anesthesia and central hemodynamics in patients with unstable angina pectoris. Anesth Analg 1989; 69:558-562. (Pubitemid 20043241)
21. Klassen GA, Bramwell RS, Bromage PR, Zborowska-Sluis DT. The effect of acute sympathectomy by epidural anesthesia on the canine coronary circulation. Anesthesiology 1980; 52:8-15.
22. Magnusdottir H, Kirno K, Ricksten SE, Elam M. High thoracic epidural anesthesia does not inhibit sympathetic nerve activity in the lower extremities. Anesthesiology 1999; 91:1299-1304.
23. Kirnö K, Friberg P, Grzegorczyk A, et al. Thoracic epidural anesthesia during coronary artery bypass surgery: Effects on cardiac sympathetic activity, myocardial blood flow and metabolism and central hemodynamics. Anesth Analg 1994; 79:1075-1081.
24. Kilickan L, Gonca S, Dalcik C, et al. General anesthesia with thoracic epidural anesthesia in the cardiopulmonary bypass surgery reduces apoptosis by upregulating antiapoptotic protein Bcl-2. J Cardiovasc Surg 2006; 47:315-322.