Spinal procaine is less neurotoxic than mepivacaine, prilocaine and bupivacaine in rats

Regional Anesthesia and Pain Medicine

Volumn 34, Issue 3, 2009, Pages 189-195

  Takenami, Tamie ^a   Yagishita, Saburo ^b   Nara, Yoshihiro ^a   Tsai, Yang Hsi ^c   Hiruma, Hiromi ^a   Kawakami, Tadashi ^a   Hoka, Sumio ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KANAGAWA REHABILITATION CENTER   (Japan)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; GLUCOSE; MEPIVACAINE; PRILOCAINE; PROCAINE; LOCAL ANESTHETIC AGENT;

ANESTHETIC RECOVERY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CAUDA EQUINA; CONTROLLED STUDY; DORSAL ROOT; ELECTRON MICROSCOPY; HISTOPATHOLOGY; MALE; MOBILIZATION; NERVE FIBER DEGENERATION; NEUROLOGIC EXAMINATION; NEUROTOXICITY; NONHUMAN; OSMOLARITY; PERCEPTIVE THRESHOLD; PH MEASUREMENT; PRIORITY JOURNAL; RAT; SPINAL ANESTHESIA; TISSUE INJURY; VENTRAL ROOT; WALKING; WHITE MATTER; ANIMAL; ANIMAL BEHAVIOR; BACK; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; CONVALESCENCE; DRUG EFFECT; INTRASPINAL DRUG ADMINISTRATION; NERVE DEGENERATION; NERVE FIBER; PAIN THRESHOLD; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL CORD; SPINAL ROOT; TIME; TOXICITY AND INTOXICATION; ULTRASTRUCTURE; WISTAR RAT;

ANESTHETICS, LOCAL; ANIMALS; AXONS; BEHAVIOR, ANIMAL; BUPIVACAINE; INJECTIONS, SPINAL; LUMBOSACRAL REGION; MALE; MEPIVACAINE; MODELS, ANIMAL; NERVE DEGENERATION; NEUROTOXICITY SYNDROMES; PAIN THRESHOLD; PRILOCAINE; PROCAINE; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL NERVE ROOTS; TIME FACTORS; WALKING;

EID: 70349232474     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1097/AAP.0b013e31819a27bd     Document Type: Article

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