Axinellamines as broad-spectrum antibacterial agents: Scalable synthesis and biology

Journal of the American Chemical Society

Volumn 136, Issue 43, 2014, Pages 15403-15413

  Rodriguez, Rodrigo A ^a   Barrios Steed, Danielle ^a   Kawamata, Yu ^a   Su, Shun ^a   Smith, Peter A ^b   Steed, Tyler C ^c   Romesberg, Floyd E ^a   Baran, Phil S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b RQx Pharmaceuticals Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY;

ANTI-BACTERIAL AGENTS; ANTIBACTERIAL ACTION; ANTIBIOTIC-RESISTANT BACTERIA; CELLULAR MORPHOLOGY; CHEMICAL ARCHITECTURE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE STRAINS; MARINE NATURAL PRODUCTS;

BACTERIA;

ANTIINFECTIVE AGENT; AXINELLAMINE; IMIDAZOLE; NATURAL PRODUCT; PYRROLE; UNCLASSIFIED DRUG; GUANIDINE; IMIDAZOLE DERIVATIVE; OXIDE; PYRROLE DERIVATIVE; SPIRO COMPOUND;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL STRUCTURE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG STABILITY; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; HUMAN; NONHUMAN; BACTERIUM; CHEMISTRY; CYCLIZATION; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACTERIA; CHEMISTRY TECHNIQUES, SYNTHETIC; CYCLIZATION; GUANIDINE; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; OXIDES; PYRROLES; SPIRO COMPOUNDS;

EID: 84908636986     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja508632y     Document Type: Article

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