Upregulation of miR-184 enhances the malignant biological behavior of human glioma cell line A172 by targeting FIH-1

Cellular Physiology and Biochemistry

Volumn 34, Issue 4, 2014, Pages 1125-1136

  Yuan, Qinghua ^a   Gao, Weida ^a   Liu, Bo ^b   Ye, Wei ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b DAQING OILFIELD CO LTD   (China)

Author keywords

FIH 1; Human glioma cancer; Malignant biological behavior; MiR 184

Indexed keywords

FACTOR INHIBITING HIF 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MATRIGEL; MEMBRANE PROTEIN; MESSENGER RNA; MIR 184; UNCLASSIFIED DRUG; HIF1AN PROTEIN, HUMAN; MICRORNA; MIRN184 MICRORNA, HUMAN; MIXED FUNCTION OXIDASE; REPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL ASSAY; CELL GROWTH; CELL INVASION; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INHIBITION KINETICS; LUCIFERASE ASSAY; PHENOTYPE; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; TUMOR CELL LINE; TUMOR INVASION;

APOPTOSIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MICRORNAS; MIXED FUNCTION OXYGENASES; NEOPLASM INVASIVENESS; REPRESSOR PROTEINS; UP-REGULATION;

EID: 84908617267     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366326     Document Type: Article

References (31)

1. Ohgaki H, Kleihues P: Genetic alterations and signaling pathways in the evolution of gliomas. Cancer Sci 2009;100:2235-2241.
2. Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, Wesseling P, Villa S, Eisenhauer E, Gorlia T, Weller M, Lacombe D, Cairncross JG, Mirimanoff RO; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009;10: 459-466.
3. Huse JT, Holland EC: Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 2010;10:319-331.
4. Garzon R, Calin GA, Croce CM: MicroRNAs in cancer. Annu Rev Med 2009;60:167-179.
5. Kozomara A, Griffiths-Jones S: miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res 2011;39:D152-157.
6. Karsy M, Albert L, Tobias ME, Murali R, Jhanwar-Uniyal M: All-trans retinoic acid modulates cancer stem cells of glioblastoma multiforme in an MAPK-dependent manner. Anticancer Res 2010;30:4915-4920.
7. Liu C, Tang DG: MicroRNA regulation of cancer stem cells. Cancer Res 2011;71:5950-5954.
8. Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M: Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. Int J Oncol 2009;35:731-740.
9. Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B: microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 2008;68:3566-3572.
10. Semenza GL: Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-732.
11. Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK: FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002;16:1466-1471.
12. McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE, Schofield CJ: Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803. Biochem J 2002;367:571-575.
13. Kasimanickam VR, Kasimanickam RK, Dernell WS: Dysregulated microRNA clusters in response to retinoic acid and CYP26B1 inhibitor induced testicular function in dogs. PLoS One 2014;9:e99433.
14. Peng Y, Guo JJ, Liu YM, Wu XL: microRNA-34a inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expression. Biosci Rep DOI: 10.1042/BSR20140020.
15. Jeon HM, Sohn YW, Oh SY, Kim SH, Beck S, Kim S, Kim H: ID4 imparts chemoresistance and cancer stemness to glioma cells by derepressing miR-9∗-mediated suppression of SOX2. Cancer Res 2011;71:3410-3421.
16. Jiang BH, Rue E, Wang GL, Roe R, Semenza GL: Dimerization, DNA binding and transactivation properties of hypoxia-inducible factor 1. J Biol Chem 1996;271:17771-17778.
17. Huang LE, Gu J, Schau M, Bunn HF: Regulation of hypoxia-inducible factor 1 alpha is mediated by an O-2-dependent degradation domain via the ubiquitin- proteasome pathway. Proc Natl Acad Sci U S A 1998;95:7987-7992.
18. Makino Y, Cao R, Svensson K, Bertilsson G, Asman M, Tanaka H, Cao Y, Berkenstam A, Poellinger L: Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 2001;414:550-554.
19. Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG: In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways. J Pathol 2005;205:530-536.
20. Zhang ZG, Zhang QN, Wang XH, Tian JH: Hypoxia-inducible factor 1 alpha (HIF-1a) as a prognostic indicator in patients with gastric tumors: a meta-analysis. Asian Pac J Cancer Prev 2013;14:4195-4198.
21. Zhu CL, Huang Q, Liu CH, Lin XS, Xie F: Prognostic value of HIF-1a expression in patients with gastric cancer. Mol Biol Rep 2013;40:6055-6062.
22. Karsy M, Arslan E, Moy F: Current progress on understanding microRNAs in glioblastoma multiforme. Genes Cancer 2012;3;3-15.
23. Ben-Hamo R, Efroni S: Gene expression and network-based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in glioblastoma multiforme progression. Genome Med 2011;3:77.
24. Sasayama T, Nishihara M, Kondoh T, Hosoda K, Kohmura E: MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC. Int J Cancer 2009;125:1407-1413.
25. Sun L, Yan W, Wang Y, Sun G, Luo H, Zhang J, Wang X, You Y, Yang Z, Liu N: MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10. Brain Res 2011;1389:9-18.
26. Peng H, Hamanaka RB, Katsnelson J, Hao LL, Yang W, Chandel NS, Lavker RM: MicroRNA-31 targets FIH-1 to positively regulate corneal epithelial glycogen metabolism. FASEB J 2012;26:3140-3147.
27. Wang E, Zhang C, Polavaram N, Liu F, Wu G, Schroeder MA, Lau JS, Mukhopadhyay D, Jiang SW, O'Neill BP, Datta K, Li J: The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme. PLoS One. 2014;23:e86102.
28. Bruick RK: Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA, 2000;97:9082-9087.
29. Kim JY, Ahn HJ, Ryu JH, Suk K, Park JH: BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J Exp Med 2004;199:113-124.
30. Torii S, Goto Y, Ishizawa T, Hoshi H, Goryo K, Yasumoto K, Fukumura H, Sogawa K: Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins. Cell Death Differ 2011;18:1711-1725.
31. Kim MC, Cui FJ, Kim Y: Hydrogen peroxide promotes epithelial to mesenchymal transition and stemness in human malignant mesothelioma cells. Asian Pac J Cancer Prev 2013;14:3625-3630.