Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins

Cell Death and Differentiation

Volumn 18, Issue 11, 2011, Pages 1711-1725

  Torii, S ^a   Goto, Y ^a   Ishizawa, T ^a   Hoshi, H ^a   Goryo, K ^a   Yasumoto, K ^a   Fukumura, H ^a   Sogawa, K ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

apoptosis; Bcl xL; HIF 1alpha; IPAS

Indexed keywords

CASPASE 3; COBALT CHLORIDE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 3ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITORY PAS DOMAIN PROTEIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL XL; PROTEIN MCL 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL STRAIN; CELL STRAIN HEK293; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CASPASE 3; CELL LINE; COBALT; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOCHONDRIA; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 80053958281     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.47     Document Type: Article

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