Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1)

Journal of Biological Chemistry

Volumn 289, Issue 44, 2014, Pages 30680-30689

  Lee, Sunhee ^a   Challa Malladi, Madhavi ^a,c   Bratton, Shawn B ^a,b   Wright, Casey W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c NEW YORK HOSPITAL QUEENS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINS; CELL DEATH; CHEMICAL ACTIVATION; ENZYMES; GENE EXPRESSION;

CELLULAR INHIBITORS; CLOSE PROXIMITY; E3 UBIQUITIN LIGASES; INHIBITOR OF APOPTOSIS; NUCLEAR FACTOR KAPPAB; PROTEIN COMPLEXES; SUBSTRATE RECOGNITION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTORS;

PROTEINS;

I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN P100; PROTEIN P52; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; BIRC2 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; UBIQUITIN PROTEIN LIGASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACULOVIRUS; BIRC3 GENE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; GENE; GENE TARGETING; HUMAN; HUMAN CELL; ICAM1 GENE; INTRACELLULAR SIGNALING; MOLECULAR RECOGNITION; NFKBIA GENE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; UBIQUITINATION; BINDING COMPETITION; CHEMISTRY; ENZYME STABILITY; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

BINDING, COMPETITIVE; ENZYME STABILITY; HEK293 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84908613357     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.587808     Document Type: Article

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