S-layers: Principles and applications

FEMS Microbiology Reviews

Volumn 38, Issue 5, 2014, Pages 823-864

  Sleytr, Uwe B ^a   Schuster, Bernhard ^a   Egelseer, Eva Maria ^a   Pum, Dietmar ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

Bacterial surface layers; Biomimetics; Crystalline cell surface layers (S layers); Nanobiotechnology; Self assembly; Synthetic biology

Indexed keywords

ANTIFOULING AGENT; EXOENZYME S; LIPOSOME; NANOPARTICLE; VACCINE; MEMBRANE PROTEIN; S-LAYER PROTEINS;

ARCHAEON; ARTICLE; BIOMINERALIZATION; BIOREMEDIATION; BIOSYNTHESIS; CELL ADHESION; CELL DIVISION; CELL FUNCTION; CELL ISOLATION; CELL SHAPE; CELL STRUCTURE; CELL SURFACE; CLINICAL TRIAL (TOPIC); CYTOCHEMISTRY; CYTOGENETICS; CYTOPATHOGENIC EFFECT; HUMAN; IN VITRO STUDY; LIPID MEMBRANE; MATERIAL COATING; MOLECULAR RECOGNITION; MORPHOGENESIS; NONHUMAN; PROTEIN LIPID INTERACTION; SURFACE LAYER; SURFACE PROPERTY; ULTRAFILTRATION; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIUM; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; ULTRASTRUCTURE;

ARCHAEA; BACTERIA (MICROORGANISMS); PROKARYOTA;

ARCHAEA; BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; MEMBRANE GLYCOPROTEINS;

EID: 84908593075     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/1574-6976.12063     Document Type: Article

References (408)

1. Abdul Halim MF, Pfeiffer F, Zou J et al. (2013) Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein. Mol Microbiol 88: 1164-1175.
2. Akca E, Claus H, Schultz N, Karbach G, Schlott B, Debaerdemaeker T, Declercq JP & König H (2002) Genes and derived amino acid sequences of S-layer proteins from mesophilic, thermophilic, and extremely thermophilic methanococci. Extremophiles 6: 351-358.
3. Albers SV & Meyer BH (2011) The archaeal cell envelope. Nat Rev Microbiol 9: 414-426.
4. Amselem S, Yogev A, Zawoznik E & Friedman D (1994) Emulsomes, a novel drug delivery technology. Proc Contr Rel Soc 21: 668-669.
5. Andresen TL, Jensen SS & Jørgensen K (2005) Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release. Prog Lipid Res 44: 68-97.
6. Antikainen J, Anton L, Sillanpaa J & Korhonen TK (2002) Domains in the S-layer protein CbsA of Lactobacillus crispatus involved in adherence to collagens, laminin and lipoteichoic acids and in self-assembly. Mol Microbiol 46: 381-394.
7. Arbing MA, Chan S, Shin A, Phan T, Ahn CJ, Rohlin L & Gunsalus RP (2012) Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans. P Natl Acad Sci USA 109: 11812-11817.
8. Ariel N, Zvi A, Grosfeld H, Gat O, Inbar Y, Velan B, Cohen S & Shafferman A (2002) Search for potential vaccine candidate open reading frames in the Bacillus anthracis virulence plasmid pXO1: in silico and in vitro screening. Infect Immun 70: 6817-6827.
9. Ausiello CM, Cerquetti M, Fedele G, Spensieri F, Palazzo R, Nasso M, Frezza S & Mastrantonio P (2006) Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells. Microbes Infect 8: 2640-2646.
10. Avall-Jääskeläinen S & Palva A (2005) Lactobacillus surface layers and their applications. FEMS Microbiol Rev 29: 511-529.
11. Avall-Jääskeläinen S, Kylä-Nikkilä K, Kahala M, Miikkulainen-Lahti T & Palva A (2002) Surface display of foreign epitopes on the Lactobacillus brevis S-layer. Appl Environ Microbiol 68: 5943-5951.
12. Avall-Jääskeläinen S, Hynonen U, Ilk N, Pum D, Sleytr UB & Palva A (2008) Identification and characterization of domains responsible for self-assembly and cell wall binding of the surface layer protein of Lactobacillus brevis ATCC 8287. BMC Microbiol 8: 165.
13. Badelt-Lichtblau H, Kainz B, Völlenkle C, Egelseer EM, Sleytr UB, Pum D & Ilk N (2009) Genetic Engineering of the S-Layer Protein SbpA of Lysinibacillus sphaericus CCM 2177 for the Generation of Functionalized Nanoarrays. Bioconjug Chem 20: 895-903.
14. Bangham AD, Standish MM & Watkins JC (1965) Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 13: 238-252.
15. 2+ triggered S-layer assembly. Nature 487: 119-122.
16. Baumeister W & Engelhardt H (1987) Three-Dimensional Structure of Bacterial Surface Layers, Vol. 6 (Harris JR & Horne RW, eds), pp. 109-154. Academic Press, Inc., London.
17. Bayley H & Cremer PS (2001) Stochastic sensors inspired by biology. Nature 413: 226-230.
18. Bergkvist M, Mark SS, Yang X, Angert ER & Batt CA (2004) Bionanofabrication of ordered nanoparticle arrays: effect of particle properties and adsorption conditions. J Phys Chem B 108: 8241-8248.
19. Beveridge TJ (1979) Surface arrays on the wall of Sporosarcina ureae. J Bacteriol 139: 1039-1048.
20. Beveridge TJ (1994) Bacterial S-layers. Curr Opin Struct Biol 4: 204-212.
21. Beveridge TJ & Graham LL (1991) Surface layers of bacteria. Microbiol Rev 55: 684-705.
22. Beveridge TJ, Pouwels PH, Sara M et al. (1997) Functions of S-layers. FEMS Microbiol Rev 20: 99-149.
23. Bingle WH, Nomellini JF & Smit J (1997a) Cell-surface display of a Pseudomonas aeruginosa strain K pilin peptide within the paracrystalline S-layer of Caulobacter crescentus. Mol Microbiol 26: 277-288.
24. Bingle WH, Nomellini JF & Smit J (1997b) Linker mutagenesis of the Caulobacter crescentus S-layer protein: toward a definition of an N-terminal anchoring region and a C-terminal secretion signal and the potential for heterologous protein secretion. J Bacteriol 179: 601-611.
25. Blaser MJ (1998) Campylobacter fetus-emerging infection and model system for bacterial pathogenesis at mucosal surfaces. Clin Infect Dis 27: 256-258.
26. Blaser MJ, Smith PF, Repine JE & Joiner KA (1988) Pathogenesis of Campylobacter fetus infections. Failure of encapsulated Campylobacter fetus to bind C3b explains serum and phagocytosis resistance. J Clin Invest 81: 1434-1444.
27. Blaser MJ, Wang E, Tummuru MK, Washburn R, Fujimoto S & Labigne A (1994) High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. Mol Microbiol 14: 453-462.
28. Blendon RJ, Benson JM, DesRoches CM, Pollard WE, Parvanta C & Herrmann MJ (2002) The impact of anthrax attacks on the American public. MedGenMed 4: 1.
29. Bobeth M, Blecha A, Blüher A, Mertig M, Korkmaz N, Ostermann K, Rödel G & Pompe W (2011) Formation of tubes during self-assembly of bacterial surface layers. Langmuir 27: 15102-15111.
30. Bohle B, Breitwieser A, Zwölfer B, Jahn-Schmid B, Sára M, Sleytr UB & Ebner C (2004) A novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity. J Immunol 172: 6642-6648.
31. Brechtel E & Bahl H (1999) In Thermoanaerobacterium thermosulfurigenes EM1 S-layer homology domains do not attach to peptidoglycan. J Bacteriol 181: 5017-5023.
32. Breitwieser A, Gruber K & Sleytr UB (1992) Evidence for an S-layer protein pool in the peptidoglycan of Bacillus stearothermophilus. J Bacteriol 174: 8008-8015.
33. Breitwieser A, Küpcü S, Howorka S, Weigert S, Langer C, Hoffmann-Sommergruber K, Scheiner O, Sleytr UB & Sára M (1996) 2-D protein crystals as an immobilization matrix for producing reaction zones in dipstick-style immunoassays. Biotechniques 21: 918-925.
34. Breitwieser A, Mader C, Schocher I, Hoffmann-Sommergruber K, Aberer W, Scheiner O, Sleytr UB & Sára M (1998) A novel dipstick developed for rapid Bet v 1-specific IgE detection: recombinant allergen immobilized via a monoclonal antibody to crystalline bacterial cell-surface layers. Allergy 53: 786-793.
35. Breitwieser A, Egelseer EM, Moll D, Ilk N, Hotzy C, Bohle B, Ebner C, Sleytr UB & Sára M (2002) A recombinant bacterial cell surface (S-layer)-major birch pollen allergen-fusion protein (rSbsC/Bet v1) maintains the ability to self- assemble into regularly structured monomolecular lattices and the functionality of the allergen. Protein Eng 15: 243-249.
36. Brinton CC, McNary JC & Carnaham J (1969) Purification and in vitro assembly of a curved network of identical protein subunits from the outer surface of a Bacillus. Bact Proc 48.
37. Brown F, Dougan G, Hoey EM, Martin S, Rima BK & Trudgett A (1993) Vaccine Design. John Wiley & Sons, England, UK.
38. Buckmire FLA (1971) A protective role for a cell wall protein layer of Spirillum serpens against infection by Bdellovibrio bacteriovorus. Bact Proc 43.
39. Calabi E, Calabi F, Phillips AD & Fairweather NF (2002) Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues. Infect Immun 70: 5770-5778.
40. Callahan C, Castanha ER, Fox KF & Fox A (2008) The Bacillus cereus containing sub-branch most closely related to Bacillus anthracis, have single amino acid substitutions in small acid-soluble proteins, while remaining sub-branches are more variable. Mol Cell Probes 22: 207-211.
41. Candela T, Mignot T, Hagnerelle X, Haustant M & Fouet A (2005) Genetic analysis of Bacillus anthracis Sap S-layer protein crystallization domain. Microbiology 151: 1485-1490.
42. Castellana ET & Cremer PS (2006) Solid supported lipid bilayers: from biophysical studies to sensor design. Surf Sci Rep 61: 429-444.
43. Cava F, de Pedro MA, Schwarz H, Henne A & Berenguer J (2004) Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria. Mol Microbiol 52: 677-690.
44. Cerquetti M, Serafino A, Sebastianelli A & Mastrantonio P (2002) Binding of Clostridium difficile to Caco-2 epithelial cell line and to extracellular matrix proteins. FEMS Immunol Med Microbiol 32: 211-218.
45. Chan YH & Boxer SG (2007) Model membrane systems and their applications. Curr Opin Chem Biol 11: 581-587.
46. Chart H, Shaw DH, Ishiguro EE & Trust TJ (1984) Structural and immunochemical homoGeneity of Aeromonas salmonicida lipopolysaccharide. J Bacteriol 158: 16-22.
47. Chauvaux S, Matuschek M & Beguin P (1999) Distinct affinity of binding sites for S-layer homologous domains in Clostridium thermocellum and Bacillus anthracis cell envelopes. J Bacteriol 181: 2455-2458.
48. Chung S, Shin SH, Bertozzi CR & De Yoreo JJ (2010) Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics. P Natl Acad Sci USA 107: 16536-16541.
49. Claus H & König H (2010) Cell envelopes of methanogens. Prokaryotic Cell Wall Compounds - Structure and Biochemistry (König H, Claus H & Varma A, eds), pp. 231-251. Springer-Verlag, Berlin.
50. Claus H, Akca E, Debaerdemaeker T, Evrard C, Declercq JP, Harris JR, Schlott B & König H (2005) Molecular organization of selected prokaryotic S-layer proteins. Can J Microbiol 51: 731-743.
51. Cline SW, Lam WL, Charlebois RL, Schalkwyk LC & Doolittle WF (1989) Transformation methods for halophilic archaebacteria. Can J Microbiol 35: 148-152.
52. Cohen-Bazire G, Kunisawa R & Pfennig N (1969) Comparative study of the structure of gas vacuoles. J Bacteriol 100: 1049-1061.
53. Comolli LR, Siegerist CE, Shin SH, Bertozzi C, Regan W, Zettl A & De Yoreo J (2013) Conformational transitions at an S-layer growing boundary resolved by cryo-TEM. Angew Chem Int Edit 52: 4829-4832.
54. Cottin-Bizonne C, Barrat J-L, Bocquet L & Charlaix E (2003) Low-friction flows of liquid at nanopatterned interfaces. Nat Mater 2: 237-240.
55. Crowther RA & Sleytr UB (1977) An analysis of the fine structure of the surface layers from two strains of Clostridia, including correction for distorted images. J Ultrastruct Res 58: 41-49.
56. Cui HF, Ye JS, Leitmannova Liu A & Ti Tien H (2006) Lipid Microvesicles: on the Four Decades of Liposome Research. Advances in Planar Lipid Bilayers and Liposomes, Vol. 4 (Leitmannova Liu A & Ti Tien H, eds), pp. 1-48. Academic Press, London.
57. de la Fuente-Núñez C, Mertens J, Smit J & Hancock REW (2012) Bacterial surface layer protects against antimicrobial peptides. Appl Environ Microbiol 78: 5452-5456.
58. De Rosa M (1996) Archaeal lipids: structural features and supramolecular organization. Thin Solid Films 284-285: 13-17.
59. De Yoreo JJ, Chung S & Nielsen MH (2013) The dynamics and energetics of matrix assembly and mineralization. Calcif Tissue Int 93: 316-328.
60. Demarche S, Sugihara K, Zambelli T, Tiefenauer L & Vörös J (2011) Techniques for recording reconstituted ion channels. Analyst 136: 1077-1089.
61. Diederich A, Sponer C, Pum D, Sleytr UB & Lösche M (1996) Reciprocal influence between the protein and lipid components of a lipid-protein membrane model. Colloids Surf, B 6: 335-346.
62. Doig P, McCubbin WD, Kay CM & Trust TJ (1993) Distribution of surface-exposed and non-accessible amino acid sequences among the two major structural domains of the S-layer protein of Aeromonas salmonicida. J Mol Biol 233: 753-765.
63. Dordic A, Egelseer EM, Tesarz M, Sleytr UB, Keller W & Pavkov-Keller T (2012) Crystallization of domains involved in self-assembly of the S-layer protein SbsC. Acta Crystallogr Sect F Struct Biol Cryst Commun 68: 1511-1514.
64. Drudy D, Calabi E, Kyne L, Sougioultzis S, Kelly E, Fairweather N & Kelly CP (2004) Human antibody response to surface layer proteins in Clostridium difficile infection. FEMS Immunol Med Microbiol 41: 237-242.
65. Dubreuil JD, Kostrzynska M, Austin JW & Trust TJ (1990) Antigenic differences among Campylobacter fetus S-layer proteins. J Bacteriol 172: 5035-5043.
66. Duncan G, Tarling CA, Bingle WH, Nomellini JF, Yamage M, Dorocicz IR, Withers SG & Smit J (2005) Evaluation of a new system for developing particulate enzymes based on the surface (S)-layer protein (RsaA) of Caulobacter crescentus: fusion with the beta-1, 4-glycanase (Cex) from the cellulolytic bacterium Cellulomonas fimi yields a robust, catalytically active product. Appl Biochem Biotechnol 127: 95-110.
67. Dworkin J, Tummuru MK & Blaser MJ (1995) Segmental conservation of sapA sequences in type B Campylobacter fetus cells. J Biol Chem 270: 15093-15101.
68. Ebner A, Kienberger F, Huber C et al. (2006) Atomic-force-microscopy imaging and molecular-recognition-force microscopy of recrystallized heterotetramers comprising an S-layer-streptavidin fusion protein. Chembiochem 7: 588-591.
69. Egelseer E, Schocher I, Sara M & Sleytr UB (1995) The S-layer from Bacillus stearothermophilus DSM 2358 functions as an adhesion site for a high-molecular-weight amylase. J Bacteriol 177: 1444-1451.
70. Egelseer EM, Schocher I, Sleytr UB & Sára M (1996) Evidence that an N-terminal S-layer protein fragment triggers the release of a cell-associated high-molecular-weight amylase in Bacillus stearothermophilus ATCC 12980. J Bacteriol 178: 5602-5609.
71. Egelseer EM, Leitner K, Jarosch M, Hotzy C, Zayni S, Sleytr UB & Sára M (1998) The S-layer proteins of two Bacillus stearothermophilus wild-type strains are bound via their N-terminal region to a secondary cell wall polymer of identical chemical composition. J Bacteriol 180: 1488-1495.
72. Egelseer EM, Idris R, Jarosch M, Danhorn T, Sleytr UB & Sára M (2000) ISBst12, a novel type of insertion-sequence element causing loss of S-layer-gene expression in Bacillus stearothermophilus ATCC 12980. Microbiology 146(Pt 9): 2175-2183.
73. Egelseer EM, Sára M, Pum D, Schuster B & Sleytr UB (2008) Genetically engineered S-layer proteins and S-layer-specific heteropolysaccharides as components of a versatile molecular construction kit for applications in nanobiotechnology. NanoBioTechnology (Shoseyov O & Levy I, eds), pp. 55-86. Humana Press, Totowa, NJ.
74. Egelseer EM, Ilk N, Pum D, Messner P, Schäffer C, Schuster B & Sleytr UB (2010) S-Layers, microbial, biotechnological applications. The Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, Vol. 7 (Flickinger MC, ed.), pp. 4424-4448. John Wiley & Sons, Inc., Hoboken, NJ.
75. Eichler J & Adams MW (2005) Posttranslational protein modification in Archaea. Microbiol Mol Biol Rev 69: 393-425.
76. Eichler J & Maupin-Furlow J (2013) Post-translation modification in Archaea: lessons from Haloferax volcanii and other haloarchaea. FEMS Microbiol Rev 37: 583-606.
77. Eichler J, Abu-Qarn M, Konrad Z, Magidovich H, Plavner N & Yurist-Doutsch S (2010) The cell envelope of Haloarchaea: staying in shape in a world of salt. Prokaryotic Cell Wall Compounds - Structure and Biochemistry (König H, Claus H & Varma A, eds), pp. 253-270. Springer-Verlag, Berlin.
78. Ellis C & Smith A (2004) Highlighting the pitfalls and possibilities of drug research. Nat Rev Drug Discov 3: 238-278.
79. Engelhardt H (2007) Mechanism of osmoprotection by archaeal S-layers: a theoretical study. J Struct Biol 160: 190-199.
80. Engelhardt H & Peters J (1998) Structural research on surface layers: a focus on stability, surface layer homology domains, and surface layer-cell wall interactions. J Struct Biol 124: 276-302.
81. Etienne-Toumelin I, Sirard JC, Duflot E, Mock M & Fouet A (1995) Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene. J Bacteriol 177: 614-620.
82. Fagan RP, Albesa-Jové D, Qazi O, Svergun DI, Brown KA & Fairweather NF (2009) Structural insights into the molecular organization of the S-layer from Clostridium difficile. Mol Microbiol 71: 1308-1322.
83. Ferner-Ortner J, Mader C, Ilk N, Sleytr UB & Egelseer EM (2007) High-affinity interaction between the S-layer protein SbsC and the secondary cell wall polymer of Geobacillus stearothermophilus ATCC 12980 determined by surface plasmon resonance technology. J Bacteriol 189: 7154-7158.
84. Ferner-Ortner-Bleckmann J, Huber-Gries C, Pavkov T, Keller W, Mader C, Ilk N, Sleytr UB & Egelseer EM (2009) The high-molecular-mass amylase (HMMA) of Geobacillus stearothermophilus ATCC 12980 interacts with the cell wall components by virtue of three specific binding regions. Mol Microbiol 72: 1448-1461.
85. Ferner-Ortner-Bleckmann J, Schrems A, Ilk N, Egelseer EM, Sleytr UB & Schuster B (2011) Multitechnique study on a recombinantly produced Bacillus halodurans laccase and an S-layer/laccase fusion protein. Biointerphases 6: 63.
86. Ferner-Ortner-Bleckmann J, Gelbmann N, Tesarz M, Egelseer EM & Sleytr UB (2013) Surface-layer lattices as patterning element for multimeric extremozymes. Small 9: 3887-3894.
87. Foligné B, Deutsch S-M, Breton J, Cousin FJ, Dewulf J, Samson M, Pot B & Jan G (2010) Promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo. Appl Environ Microbiol 76: 8259-8264.
88. Fujino T, Beguin P & Aubert JP (1993) Organization of a Clostridium thermocellum gene cluster encoding the cellulosomal scaffolding protein CipA and a protein possibly involved in attachment of the cellulosome to the cell surface. J Bacteriol 175: 1891-1899.
89. Galdiero S, Galdiero M & Pedone C (2007) β-barrel membrane bacterial proteins: structure, function, assembly and interaction with lipids. Curr Protein Pept Sci 8: 63-82.
90. Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C & Galdiero M (2010) The presence of a single N-terminal histidine residue enhances the fusogenic properties of a membranotropic peptide derived from herpes simplex virus type 1 glycoprotein H. J Biol Chem 285: 17123-17136.
91. Gerstein M & Hegyi H (1998) Comparing genomes in terms of protein structure: surveys of a finite parts list. FEMS Microbiol Rev 22: 277-304.
92. Gerstmayr M, Ilk N, Schabussova I, Jahn-Schmid B, Egelseer EM, Sleytr UB, Ebner C & Bohle B (2007) A novel approach to specific allergy treatment: the recombinant allergen-S-layer fusion protein rSbsC-Bet v 1 matures dendritic cells that prime Th0/Th1 and IL-10-producing regulatory T cells. J Immunol 179: 7270-7275.
93. Gerstmayr M, Ilk N, Jahn-Schmid B, Sleytr UB & Bohle B (2009) Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity. Int Arch Allergy Immunol 149: 231-238.
94. Gil D, Carazo JM & Marabini R (2006) On the nature of 2D crystal unbending. J Struct Biol 156: 546-555.
95. Göbel C, Schuster B, Baurecht D, Sleytr UB & Pum D (2010) S-layer templated bioinspired synthesis of silica. Colloids Surf B Biointerfaces 75: 565-572.
96. Graham LL, Beveridge TJ & Nanninga N (1991) Periplasmic space and the concept of the periplasm. Trends Biochem Sci 16: 328-329.
97. Graham LL, Friel T & Woodman RL (2008) Fibronectin enhances Campylobacter fetus interaction with extracellular matrix components and INT 407 cells. Can J Microbiol 54: 37-47.
98. Gruber K & Sleytr UB (1988) Localized insertion of new S-layer during growth of Bacillus stearothermophilus strains. Arch Microbiol 149: 485-491.
99. Gruber K & Sleytr UB (1991) Influence of an S-layer on surface properties of Bacillus stearothermophilus. Arch Microbiol 156: 181-185.
100. Guerrant RL, Lahita RG, Winn WC Jr & Roberts RB (1978) Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections. Am J Med 65: 584-592.
101. Gufler PC, Pum D, Sleytr UB & Schuster B (2004) Highly robust lipid membranes on crystalline S-layer supports investigated by electrochemical impedance spectroscopy. Biochim Biophys Acta 1661: 154-165.
102. Györvary E, Wetzer B, Sleytr UB, Sinner A, Offenhäusser A & Knoll W (1999) Lateral diffusion of lipids in silane-, dextran-, and S-layer-supported mono- and bilayers. Langmuir 15: 1337-1347.
103. Györvary ES, Stein O, Pum D & Sleytr UB (2003) Self-assembly and recrystallization of bacterial S-layer proteins at silicon supports imaged in real time by atomic force microscopy. J Microsc 212: 300-306.
104. Györvary E, Schroedter A, Talapin DV, Weller H, Pum D & Sleytr UB (2004) Formation of nanoparticle arrays on S-layer protein lattices. J Nanosci Nanotechnol 4: 115-120.
105. Haft DH, Payne SH & Selengut JD (2012) Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification. J Bacteriol 194: 36-48.
106. Hall SR, Shenton W, Engelhardt H & Mann S (2001) Site-specific organization of gold nanoparticles by biomolecular templating. Chemphyschem 3: 184-186.
107. Hancock REW & Chapple DS (1999) Peptide antibiotics. Antimicrob Agents Chemother 43: 1317-1323.
108. Hanford MJ & Peeples TL (2002) Archaeal tetraether lipids: unique structures and applications. Appl Biochem Biotechnol 97: 45-62.
109. Harris WF (1975) Negative wedge disclinations of rotation 2pi radians and topological changes of membraneous systems. Philos Mag 32: 37-41.
110. Harris WF (1978) Dislocations, disclinations and dispirations: distraction in very naughty crystals. S Afr J Sci 74: 332-338.
111. Harris WF & Scriven LE (1970) Function of dislocations in cell walls and membranes. Nature 228: 827-829.
112. Harris WF & Scriven LE (1971) Intrinsic disclinations as dislocation sources and sinks in surface crystals. J Appl Phys 42: 3309-3312.
113. Henderson R, Baldwin JM, Downing KH, Lepault J & Zemlin F (1986) Structure of purple membrane from Halobacterium halobium: recording, measurement and evaluation of electron micrographs at 3.5 Å resolution. Ultramicroscopy 19: 147-178.
114. Hianik T, Küpcü S, Sleytr UB, Rybar P, Krivanek R & Kaatze U (1999) Interaction of crystalline bacterial cell surface proteins with lipid bilayers in liposomes. Coll Surf A 147: 331-339.
115. Hirn R, Schuster B, Sleytr UB & Bayerl TM (1999) The effect of S-layer protein adsorption and crystallization on the collective motion of a planar lipid bilayer studied by dynamic light scattering. Biophys J 77: 2066-2074.
116. Hollmann A, Delfederico L, Glikmann G, De Antoni G, Semorile L & Disalvo EA (2007) Characterization of liposomes coated with S-layer proteins from Lactobacilli. Biochim Biophy Acta 1768: 393-400.
117. Holt SC & Leadbetter ER (1969) Comparative ultrastructure of selected aerobic spore forming bacteria: a freeze-etching study. Bacteriol Rev 33: 346-378.
118. Horejs C, Pum D, Sleytr UB & Tscheliessnig R (2008) Structure prediction of an S-layer protein by the mean force method. J Chem Phys 128: 065106.
119. Horejs C, Pum D, Sleytr UB, Peterlik H, Jungbauer A & Tscheliessnig R (2010) Surface layer protein characterization by small angle x-ray scattering and a fractal mean force concept: from protein structure to nanodisk assemblies. J Chem Phys 133: 175102.
120. Horejs C, Ristl R, Tscheliessnig R, Sleytr UB & Pum D (2011a) Single-molecule force spectroscopy reveals the individual mechanical unfolding pathways of a surface layer protein. J Biol Chem 286: 27416-27424.
121. Horejs C, Gollner H, Pum D, Sleytr UB, Peterlik H, Jungbauer A & Tscheliessnig R (2011b) Atomistic structure of monomolecular surface layer self-assemblies: toward functionalized nanostructures. ACS Nano 5: 2288-2297.
122. Houwink AL (1953) A macromolecular monolayer in the cell wall of Spirillum spec. Biochim Biophys Acta 10: 360-366.
123. Houwink AL & Le Poole JB (1952) Eine Struktur in der Zellmembran einer Bakterie. Physikalische Verhandlungen 3: 98.
124. Hovmöller S, Sjögren A & Wang DN (1988) The structure of crystalline bacterial surface layers. Prog Biophys Mol Biol 51: 131-163.
125. Howard LV, Dalton DD & McCoubrey JWK (1982) Expansion of the tetragonally arrayed cell wall protein layer during growth of Bacillus sphaericus. J Bacteriol 149: 748-757.
126. Huber C, Ilk N, Rünzler D, Egelseer EM, Weigert S, Sleytr UB & Sára M (2005) The three S-layer-like homology motifs of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 are not sufficient for binding to the pyruvylated secondary cell wall polymer. Mol Microbiol 55: 197-205.
127. Huber C, Egelseer EM, Ilk N, Sleytr UB & Sára M (2006a) S-layer-streptavidin fusion proteins and S-layer-specific heteropolysaccharides as part of a biomolecular construction kit for application in nanobiotechnology. Microelectron Eng 83: 1589-1593.
128. Huber C, Liu J, Egelseer EM, Moll D, Knoll W, Sleytr UB & Sára M (2006b) Heterotetramers formed by an S-layer-streptavidin fusion protein and core-streptavidin as nanoarrayed template for biochip development. Small 2: 142-150.
129. Hynonen U & Palva A (2013) Lactobacillus surface layer proteins: structure, function and applications. Appl Microbiol Biotechnol 97: 5225-5243.
130. Ilk N, Kosma P, Puchberger M, Egelseer EM, Mayer HF, Sleytr UB & Sára M (1999) Structural and functional analyses of the secondary cell wall polymer of Bacillus sphaericus CCM 2177 that serves as an S-layer-specific anchor. J Bacteriol 181: 7643-7646.
131. Ilk N, Völlenkle C, Egelseer EM, Breitwieser A, Sleytr UB & Sára M (2002) Molecular characterization of the S-layer gene, sbpA, of Bacillus sphaericus CCM 2177 and production of a functional S-layer fusion protein with the ability to recrystallize in a defined orientation while presenting the fused allergen. Appl Environ Microbiol 68: 3251-3260.
132. Ilk N, Küpcü S, Moncayo G, Klimt S, Ecker RC, Hofer-Warbinek R, Egelseer EM, Sleytr UB & Sára M (2004) A functional chimaeric S-layer-enhanced green fluorescent protein to follow the uptake of S-layer-coated liposomes into eukaryotic cells. Biochem J 379: 441-448.
133. Ilk N, Egelseer EM & Sleytr UB (2011a) S-layer fusion proteins-construction principles and applications. Curr Opin Biotechnol 22: 824-831.
134. Ilk N, Schumi CT, Bohle B, Egelseer EM & Sleytr UB (2011b) Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive Bacillus subtilis 1012 for the potential application as vaccines for immunotherapy of atopic allergy. Microb Cell Fact 10: 6.
135. Jackman JA, Knoll W & Cho N-J (2012) Biotechnology applications of tethered lipid bilayer membranes. Materials 5: 2637-2657.
136. Jaenicke R, Welsch R, Sára M & Sleytr UB (1985) Stability and self-assembly of the S-layer protein of the cell wall of Bacillus stearothermophilus. Biol Chem Hoppe Seyler 366: 663-670.
137. Jahn-Schmid B, Messner P, Unger FM, Sleytr UB, Scheiner O & Kraft D (1996a) Toward selective elicitation of TH1-controlled vaccination responses: vaccine applications of bacterial surface layer proteins. J Biotechnol 44: 225-231.
138. Jahn-Schmid B, Graninger M, Glozik M, Küpcü S, Ebner C, Unger FM, Sleytr UB & Messner P (1996b) Immunoreactivity of allergen (Bet v 1) conjugated to crystalline bacterial cell surface layers (S-layers). Immunotechnology 2: 103-113.
139. Jahn-Schmid B, Siemann U, Zenker A, Bohle B, Messner P, Unger FM, Sleytr UB, Scheiner O, Kraft D & Ebner C (1997) Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12. Int Immunol 9: 1867-1874.
140. Janesch B, Messner P & Schäffer C (2013) Are the surface layer homology domains essential for cell surface display and glycosylation of the S-layer protein from Paenibacillus alvei CCM 2051T? J Bacteriol 195: 565-575.
141. Jarosch M, Egelseer EM, Mattanovich D, Sleytr UB & Sára M (2000) S-layer gene sbsC of Bacillus stearothermophilus ATCC 12980: molecular characterization and heterologous expression in Escherichia coli. Microbiology 146(Pt 2): 273-281.
142. Jarosch M, Egelseer EM, Huber C, Moll D, Mattanovich D, Sleytr UB & Sára M (2001) Analysis of the structure-function relationship of the S-layer protein SbsC of Bacillus stearothermophilus ATCC 12980 by producing truncated forms. Microbiology 147: 1353-1363.
143. Ji Y-L, An Q-F, Zhao Q, Sun W-D, Lee K-R, Chen H-L & Gao C-J (2012) Novel composite nanofiltration membranes containing zwitterions with high permeate flux and improved anti-fouling performance. J Membr Sci 390-391: 243-253.
144. Jing H, Takagi J, Liu JH, Lindgren S, Zhang RG, Joachimiak A, Wang JH & Springer TA (2002) Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins. Structure 10: 1453-1464.
145. Kainz B, Steiner K, Sleytr UB, Pum D & Toca-Herrera JL (2010a) Fluorescence energy transfer in the bi-fluorescent S-layer tandem fusion protein ECFP-SgsE-YFP. J Struct Biol 172: 276-283.
146. Kainz B, Steiner K, Moller M, Pum D, Schäffer C, Sleytr UB & Toca-Herrera JL (2010b) Absorption, steady-state fluorescence, fluorescence lifetime, and 2D self-assembly properties of engineered fluorescent S-layer fusion proteins of Geobacillus stearothermophilus NRS 2004/3a. Biomacromolecules 11: 207-214.
147. Kandiba L, Guan Z & Eichler J (2013) Lipid modification gives rise to two distinct Haloferax volcanii S-layer glycoprotein populations. Biochim Biophy Acta 1828: 938-943.
148. Keizer HM, Dorvel BR, Andersson M et al. (2007) Functional ion channels in tethered bilayer membranes - implications for biosensors. ChemBioChem 8: 1246-1250.
149. Keizer HM, Andersson M, Chase C, Laratta WP, Proemsey JB, Tabb J, Long JR & Duran RS (2008) Prolonged stochastic single ion channel recordings in S-layer protein stabilized lipid bilayer membranes. Colloids Surf, B 65: 178-185.
150. Kelly CP & LaMont JT (1998) Clostridium difficile infection. Annu Rev Med 49: 375-390.
151. Kepplinger C (2007) Anchoring of lipid assemblies to native and modified S-layer lattices - a nanobiotechnological study. Thesis, University of Natural Resources and Life Sciences, Vienna, Austria.
152. Kepplinger C, Ilk N, Sleytr UB & Schuster B (2009) Intact lipid vesicles reversibly tethered to a bacterial S-layer protein lattice. Soft Matter 5: 325-333.
153. Kern J, Wilton R, Zhang R, Binkowski TA, Joachimiak A & Schneewind O (2011) Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem 286: 26042-26049.
154. Kiene E (2011) Potential and limitations of S-layers as support for planar lipid bilayers. Thesis, University of Natural Resources and Life Sciences, Vienna, Austria.
155. Kikuchi A, Sagami H & Ogura K (1999) Evidence for covalent attachment of diphytanylglyceryl phosphate to the cell-surface glycoprotein of Halobacterium halobium. J Biol Chem 274: 18011-18016.
156. Klingl A, Moissl-Eichinger C, Wanner G, Zweck J, Huber H, Thomm M & Rachel R (2011) Analysis of the surface proteins of Acidithiobacillus ferrooxidans strain SP5/1 and the new, pyrite-oxidizing Acidithiobacillus isolate HV2/2, and their possible involvement in pyrite oxidation. Arch Microbiol 193: 867-882.
157. Knoll W, Naumann R, Friedrich M et al. (2008) Solid supported lipid membranes: new concepts for the biomimetic functionalization of solid surfaces. Biointerphases 3: FA125-FA135.
158. König H, Claus H & Akca E (2004) Cell wall structure of mesophilic, thermophilic and hyperthermophilic archaea. Origins (Seckbach J, ed.), pp. 283-298. Kluwer, Dordrecht.
159. König H, Claus H & Varma A (2010) Prokaryotic Cell Wall Compounds - Structure and Biochemistry. Springer, Berlin.
160. Konrad Z & Eichler J (2002) Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation. Biochem J 366: 959-964.
161. Konstantinov SR, Smidt H, de Vos WM et al. (2008) S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. P Natl Acad Sci USA 105: 19474-19479.
162. Kosma P, Wugeditsch T, Christian R, Zayni S & Messner P (1995) Glycan structure of a heptose-containing S-layer glycoprotein of Bacillus thermoaerophilus. Glycobiology 5: 791-796.
163. Koval SF (1993) Predation on bacteria possessing S-layers. Advances on Paracrystalline Bacterial Surface Layers, Vol. 252 (Beveridge TJ & Koval SF, eds), pp. 85-92. Plenum Press, New York.
164. Koval SF & Murray RG (1984) The isolation of surface array proteins from bacteria. Can J Biochem Cell Biol 62: 1181-1189.
165. Krivanek R, Rybar P, Küpcü S, Sleytr UB & Hianik T (2002) Affinity interactions on a liposome surface detected by ultrasound velocimetry. Bioelectrochemistry 55: 57-59.
166. Küpcü S, Sára M & Sleytr UB (1993) Influence of covalent attachment of low molecular weight substances on the rejection and adsorption properties of crystalline proteinaceous ultrafiltration membranes. Desalination 90: 65-76.
167. Küpcü S, Sára M & Sleytr UB (1995a) Liposomes coated with crystalline bacterial cells surface protein (S-layer) as immobilization structures for macromolecules. Biochim Biophys Acta 1235: 263-269.
168. Küpcü S, Mader C & Sára M (1995b) The crystalline cell surface layer of Thermoanaerobacter thermohydrosulfuricus L111-69 as an immobilization matrix: influence of the morphological properties and the pore size of the matrix on activity loss of covalently bound enzymes. Biotechnol Appl Biochem 21: 275-286.
169. Küpcü S, Sleytr UB & Sara M (1996) Two-dimensional paracrystalline glycoprotein S-layers as a novel matrix for the immobilization of human IgG and their use as microparticles in immunoassays. J Immunol Methods 196: 73-84.
170. Küpcü S, Lohner K, Mader C & Sleytr UB (1998) Microcalorimetric study on the phase behaviour of S-layer coated liposomes. Mol Membr Biol 15: 69-74.
171. Larisch V-D (2012) Characterization of the ryanodine receptor 1 in model lipid membranes. Master Thesis, University of Natural Resources and Life Sciences, Vienna, Austria.
172. Lemaire M, Ohayon H, Gounon P, Fujino T & Beguin P (1995) OlpB, a new outer layer protein of Clostridium thermocellum, and binding of its S-layer-like domains to components of the cell envelope. J Bacteriol 177: 2451-2459.
173. Lemaire M, Miras I, Gounon P & Beguin P (1998) Identification of a region responsible for binding to the cell wall within the S-layer protein of Clostridium thermocellum. Microbiology 144: 211-217.
174. Linder MB (2009) Hydrophobins: proteins that self assemble at interfaces. Curr Opin Colloid Interface Sci 14: 356-363.
175. Lopez AE, Moreno-Flores S, Pum D, Sleytr UB & Toca-Herrera JL (2010) Surface dependence of protein nanocrystal formation. Small 6: 396-403.
176. López AE, Pum D, Sleytr UB & Toca-Herrera JL (2011) Influence of surface chemistry and protein concentration on the adsorption rate and S-layer crystal formation. Phys Chem Chem Phys 13: 11905-11913.
177. Lortal S, van Heijenoort J, Gruber K & Sleytr UB (1992) S-layer of Lactobacillus helveticus ATCC 12046: isolation, chemical characterization and re-formation after extraction with lithium chloride. J Gen Microbiol 138: 611-618.
178. Lortal S, Rouault A, Cesselin B & Sleytr UB (1993) Paracrystalline surface layers of dairy propionibacteria. Appl Environ Microbiol 59: 2369-2374.
179. Mader C, Küpcü S, Sára M & Sleytr UB (1999) Stabilizing effect of an S-layer on liposomes towards thermal or mechanical stress. Biochim Biophys Acta 1418: 106-116.
180. Mader C, Küpcü S, Sleytr UB & Sára M (2000) S-layer-coated liposomes as a versatile system for entrapping and binding target molecules. Biochim Biophys Acta 1463: 142-150.
181. Mader C, Huber C, Moll D, Sleytr UB & Sára M (2004) Interaction of the crystalline bacterial cell surface layer protein SbsB and the secondary cell wall polymer of Geobacillus stearothermophilus PV72 assessed by real-time surface plasmon resonance biosensor technology. J Bacteriol 186: 1758-1768.
182. Malcolm AJ, Messner P, Sleytr UB, Smith RH & Unger FM (1993a) Crystalline bacterial cell surface layers (S-layers) as combined carrier/adjuvants for conjugated vaccines. Immobilized Macromolecules: Application Potentials (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 195-207. Springer-Verlag, London, UK.
183. Malcolm AJ, Best MW, Szarka RJ, Mosleh Z, Unger FM, Messner P & Sleytr UB (1993b) Surface layers of Bacillus alvei as a carrier for a Streptococcus pneunoniae conjugate vaccine. Bacterial Paracrystalline Surface Layers, Vol. 252 (Beveridge J & Koval SF, eds), pp. 219-233. Plenum Press, New York, NY.
184. Martinez MG, Prado Acosta M, Candurra NA & Ruzal SM (2012) S-layer proteins of Lactobacillus acidophilus inhibits JUNV infection. Biochem Biophys Res Commun 422: 590-595.
185. Maslyuk VV, Mertig I, Bredow T, Mertig M, Vyalikh DV & Molodtsov SL (2008) Electronic structure of bacterial surface protein layers. Phys Rev B 77: 45419.
186. May A, Pusztahelyi T, Hoffmann N, Fischer RJ & Bahl H (2006) Mutagenesis of conserved charged amino acids in SLH domains of Thermoanaerobacterium thermosulfurigenes EM1 affects attachment to cell wall sacculi. Arch Microbiol 185: 263-269.
187. Mertig M, Kirsch R, Pompe W & Engelhardt H (1999) Fabrication of highly orineted nanocluster arrays by biomolecular templating. Eur Phys J D D 9: 45-48.
188. Mescher MF & Strominger JL (1976) Purification and characterization of a prokaryotic glucoprotein from the cell envelope of Halobacterium salinarium. J Biol Chem 251: 2005-2014.
189. Mesnage S, Tosi-Couture E, Mock M, Gounon P & Fouet A (1997) Molecular characterization of the Bacillus anthracis main S-layer component: evidence that it is the major cell-associated antigen. Mol Microbiol 23: 1147-1155.
190. Mesnage S, Tosi-Couture E, Gounon P, Mock M & Fouet A (1998) The capsule and S-layer: two independent and yet compatible macromolecular structures in Bacillus anthracis. J Bacteriol 180: 52-58.
191. Mesnage S, Tosi-Couture E & Fouet A (1999a) Production and cell surface anchoring of functional fusions between the SLH motifs of the Bacillus anthracis S-layer proteins and the Bacillus subtilis levansucrase. Mol Microbiol 31: 927-936.
192. Mesnage S, Tosi-Couture E, Mock M & Fouet A (1999b) The S-layer homology domain as a means for anchoring heterologous proteins on the cell surface of Bacillus anthracis. J Appl Microbiol 87: 256-260.
193. Mesnage S, Weber-Levy M, Haustant M, Mock M & Fouet A (1999c) Cell surface-exposed tetanus toxin fragment C produced by recombinant Bacillus anthracis protects against tetanus toxin. Infect Immun 67: 4847-4850.
194. Mesnage S, Fontaine T, Mignot T, Delepierre M, Mock M & Fouet A (2000) Bacterial SLH domain proteins are non-covalently anchored to the cell surface via a conserved mechanism involving wall polysaccharide pyruvylation. EMBO J 19: 4473-4484.
195. Messner P & Sleytr UB (1991a) Bacterial surface layer glycoproteins. Glycobiology 1: 545-551.
196. Messner P & Sleytr UB (1991b) The use of freeze-etching and freeze-drying to evaluate crystalline cell surface layers (S-layers). Microbial Cell Surface Analysis Structural and Physicochemical Methods (Mozes N, Handley PS, Busscher HJ & Rouxhet PG, eds), pp. 109-125. VCH Publishers, New York.
197. Messner P & Sleytr UB (1992) Crystalline bacterial cell-surface layers. Adv Microb Physiol 33: 213-275.
198. Messner P, Pum D & Sleytr UB (1986a) Characterization of the ultrastructure and the self-assembly of the surface layer of Bacillus stearothermophilus strain NRS 2004/3a. J Ultrastruct Mol Struct Res 97: 73-88.
199. Messner P, Pum D, Sára M, Stetter KO & Sleytr UB (1986b) Ultrastructure of the cell envelope of the archaebacteria Thermoproteus tenax and Thermoproteus neutrophilus. J Bacteriol 166: 1046-1054.
200. Messner P, Mazid MA, Unger FM & Sleytr UB (1992) Artificial antigens. Synthetic carbohydrate haptens immobilized on crystalline bacterial surface layer glycoproteins. Carbohydr Res 233: 175-184.
201. Messner P, Unger FM & Sleytr UB (1996) Vaccine development based on S-layer technology. Crystalline Bacterial Cell Surface Proteins (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 161-173. R.G. Landes, Academic Press, Austin, TX.
202. Messner P, Steiner K, Zarschler K & Schäffer C (2008) S-layer nanoglycobiology of bacteria. Carbohydr Res 343: 1934-1951.
203. Messner P, Egelseer EM, Sleytr UB & Schäffer C (2009) Bacterial surface layer glycoproteins and 'non-classical' secondary cell wall polymers. Microbial Glycobiology: Structures, Relevance and Applications (Moran A, Holst O, Brennan PJ & von Itzstein M, eds), pp. 109-128. Elsevier, San Diego.
204. Messner P, Schäffer C, Egelseer EM & Sleytr UB (2010) Occurrence, structure, chemistry, genetics, morphogenesis, and function of S-layers. Prokaryotic Cell Wall Compounds - Structure and Biochemistry, Vol. Chapter 2 (König H, Claus H & Varma A, eds), pp. 53-109. Springer, Heidelberg, Germany.
205. Messner P, Schäffer C & Kosma P (2013) Bacterial cell-envelope glycoconjugates. Adv Carbohydr Chem Biochem 69: 209-272.
206. Mignot T, Mesnage S, Couture-Tosi E, Mock M & Fouet A (2002) Developmental switch of S-layer protein synthesis in Bacillus anthracis. Mol Microbiol 43: 1615-1627.
207. Moll D, Huber C, Schlegel B, Pum D, Sleytr UB & Sára M (2002) S-layer-streptavidin fusion proteins as template for nanopatterned molecular arrays. P Natl Acad Sci USA 99: 14646-14651.
208. Moreno-Flores S, Kasry A, Butt HJ, Vavilala C, Schmittel M, Pum D, Sleytr UB & Toca-Herrera JL (2008) From native to non-native two-dimensional protein lattices through underlying hydrophilic/hydrophobic nanoprotrusions. Angew Chem Int Ed 47: 4707-4710.
209. Müller DJ, Baumeister W & Engel A (1996) Conformational change of the hexagonally packed intermediate layer of Deinococcus radiodurans monitored by atomic force microscopy. J Bacteriol 178: 3025-3030.
210. Müller DJ, Baumeister W & Engel A (1999) Controlled unzipping of a bacterial surface layer with atomic force microscopy. P Natl Acad Sci USA 96: 13170-13174.
211. Nabarro FRN & Harris WF (1971) Presence and function of disclinations in surface coats of unicellular organisms. Nature 232: 423.
212. Neubauer A, Pum D & Sleytr UB (1993) An amperometric glucose sensor based on isoporous crystalline protein membranes as immobilization matrix. Anal Lett 26: 1347-1360.
213. Neubauer A, Hödl C, Pum D & Sleytr UB (1994) A multistep enzyme sensor for sucrose based on S-layer microparticles as immobilization matrix. Anal Lett 27: 849-865.
214. Neubauer A, Pum D & Sleytr UB (1996) Fibre-optic glucose biosensor using enzyme membranes with 2-D crystalline structure. Biosens Bioelectron 11: 317-325.
215. Ni Eidhin DB, O'Brien JB, McCabe MS, Athie-Morales V & Kelleher DP (2008) Active immunization of hamsters against Clostridium difficile infection using surface-layer protein. FEMS Immunol Med Microbiol 52: 207-218.
216. Nikolelis DP, Hianik T & Krull UJ (1999) Biosensors based on thin lipid films and liposomes. Electroanalysis 11: 7-15.
217. Nomellini JF, Küpcü S, Sleytr UB & Smit J (1997) Factors controlling in vitro recrystallization of the Caulobacter crescentus paracrystalline S-layer. J Bacteriol 179: 6349-6354.
218. Nomellini JF, Duncan G, Dorocicz IR & Smit J (2007) S-layer mediated display of the IgG-binding domain of streptococcal Protein G on the surface of Caulobacter crescentus - development of an immuno-active reagent. Appl Environ Microbiol 73: 3245-3253.
219. Nomellini JF, Li C, Lavallee D, Shanina I, Cavacini LA, Horwitz MS & Smit J (2010) Development of an HIV-1 specific microbicide using Caulobacter crescentus S-layer mediated display of CD4 and MIP1alpha. PLoS One 5: e10366.
220. Norville JE, Kelly DF, Knight TF Jr, Belcher AM & Walz T (2007) 7A projection map of the S-layer protein sbpA obtained with trehalose-embedded monolayer crystals. J Struct Biol 160: 313-323.
221. Novotny R, Pföstl A, Messner P & Schäffer C (2004) Genetic organization of chromosomal S-layer glycan biosynthesis loci of Bacillaceae. Glycoconj J 20: 435-447.
222. Nußer E, Hartmann E, Allmeier H, König H, Paul G & Stetter KO (1988) A glycoprotein surface layer covers the pseudomurein sacculus of the extreme thermophile Methanothermus fervidus. Crystalline Bacterial Cell Surface Layers (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 21-25. Springer-Verlag, Berlin.
223. O'Brien JB, McCabe MS, Athie-Morales V, McDonald GS, Ni Eidhin DB & Kelleher DP (2005) Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins. FEMS Microbiol Lett 246: 199-205.
224. O'Connor E & Shand R (2002) Halocins and sulfolobicins: the emerging story of archaeal protein and peptide antibiotics. J Ind Microbiol Biotechnol 28: 23-31.
225. Patel J, Zhang Q, McKay RM, Vincent R & Xu Z (2010) Genetic engineering of Caulobacter crescentus for removal of cadmium from water. Appl Biochem Biotechnol 160: 232-243.
226. Pavkov T, Egelseer EM, Tesarz M, Svergun DI, Sleytr UB & Keller W (2008) The structure and binding behavior of the bacterial cell surface layer protein SbsC. Structure 16: 1226-1237.
227. Pavkov-Keller T, Howorka S & Keller W (2011) The structure of bacterial S-layer proteins. Molecular Assembly in Natural and Engineered Systems, Vol. 103 (Howorka S, ed.), pp. 73-130. Elsevier Academic Press Inc., Burlington.
228. Pechine S, Deneve C, Le Monnier A, Hoys S, Janoir C & Collignon A (2011) Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen. FEMS Immunol Med Microbiol 63: 73-81.
229. Penfold J, Thomas RK & Shen HH (2012) Adsorption and self-assembly of biosurfactants studied by neutron reflectivity and small angle neutron scattering: glycolipids, lipopeptides and proteins. Soft Matter 8: 578-591.
230. Petersen BO, Sára M, Mader C et al. (2008) Structural characterization of the acid-degraded secondary cell wall polymer of Geobacillus stearothermophilus PV72/p2. Carbohydr Res 343: 1346-1358.
231. Picher MM, Küpcü S, Huang CJ, Dostalek J, Pum D, Sleytr UB & Ertl P (2013) Nanobiotechnology advanced antifouling surfaces for the continuous electrochemical monitoring of glucose in whole blood using a lab-on-a-chip. Lab Chip 13: 1780-1789.
232. Pleschberger M, Neubauer A, Egelseer EM, Weigert S, Lindner B, Sleytr UB, Muyldermans S & Sára M (2003) Generation of a functional monomolecular protein lattice consisting of an S-layer fusion protein comprising the variable domain of a camel heavy chain antibody. Bioconjug Chem 14: 440-448.
233. Pleschberger M, Saerens D, Weigert S, Sleytr UB, Muyldermans S, Sára M & Egelseer EM (2004) An S-layer heavy chain camel antibody fusion protein for generation of a nanopatterned sensing layer to detect the prostate-specific antigen by surface plasmon resonance technology. Bioconjug Chem 15: 664-671.
234. Pleschberger M, Hildner F, Rünzler D, Gelbmann N, Mayer HF, Sleytr UB & Egelseer EM (2013) Identification of a novel gene cluster in the upstream region of the S-layer gene sbpA involved in cell wall metabolism of Lysinibacillus sphaericus CCM 2177 and characterization of the recombinantly produced autolysin and pyruvyl transferase. Arch Microbiol 195: 323-337.
235. Pollmann K, Raff J, Merroun M, Fahmy K & Selenska-Pobell S (2006) Metal binding by bacteria from uranium mining waste piles and its technological applications. Biotechnol Adv 24: 58-68.
236. Poobalane S, Thompson KD, Ardo L, Verjan N, Han HJ, Jeney G, Hirono I, Aoki T & Adams A (2010) Production and efficacy of an Aeromonas hydrophila recombinant S-layer protein vaccine for fish. Vaccine 28: 3540-3547.
237. Posch G, Andrukhov O, Vinogradov E, Lindner B, Messner P, Holst O & Schäffer C (2013) Structure and immunogenicity of the rough-type lipopolysaccharide from the periodontal pathogen Tannerella forsythia. Clin Vaccine Immunol 20: 945-953.
238. Powell MF & Newman MJ (1995) Vaccine Design: The Subunit and Adjuvant Approach. Plenum Press, New York, NY.
239. Prangishvili D, Holz I, Stieger E, Nickell S, Kristjansson JK & Zillig W (2000) Sulfolobicins, specific proteinaceous toxins produced by strains of the extremely thermophilic archaeal genus Sulfolobus. J Bacteriol 182: 2985-2988.
240. Pum D & Sleytr UB (1994) Large-scale reconstruction of crystalline bacterial surface layer proteins at the air-water interface and on lipids. Thin Solid Films 244: 882-886.
241. Pum D & Sleytr UB (1995a) Monomolecular reassembly of a crystalline bacterial cell surface layer (S layer) on untreated and modified silicon surfaces. Supramol Sci 2: 193-197.
242. Pum D & Sleytr UB (1995b) Anisotropic crystal growth of the S-layer of Bacillus sphaericus CCM 2177 at the air/water interface. Colloids Surf A Physicochem Eng Asp 102: 99-104.
243. Pum D & Sleytr UB (2009) S-layer proteins for assembling ordered nanoparticle arrays. Nanobioelectronics - For Electronics, Biology, and Medicine (Offenhäuser A & Rinaldi R, eds), pp. 167-180. Springer, New York.
244. Pum D, Sára M & Sleytr UB (1989) Structure, surface charge, and self-assembly of the S-layer lattice from Bacillus coagulans E38-66. J Bacteriol 171: 5296-5303.
245. Pum D, Messner P & Sleytr UB (1991) Role of the S layer in morphogenesis and cell division of the archaebacterium Methanocorpusculum sinense. J Bacteriol 173: 6865-6873.
246. Pum D, Weinhandl M, Hödl C & Sleytr UB (1993) Large-scale recrystallization of the S-layer of Bacillus coagulans E38-66 at the air/water interface and on lipid films. J Bacteriol 175: 2762-2766.
247. Pum D, Sara M, Schuster B & Sleytr UB (2006) Bacterial surface layer proteins: a simple but versatile biological self-assembly system in Nature. Nanotechnology: Science and Computation (Chen J, Jonoska N & Rozenberg G, ed.), pp. 277-292. Springer, Berlin.
248. Pum D, Tang J, Hinterdorfer P, Toca-Herrera JL & Sleytr UB (2010) S-layer protein lattices studied by scanning force microscopy. Biomimetic and Bioinspired Nanomaterials, Vol. 7 (Kumar C, ed.), pp. 459-510. Wiley-VCH, Weinheim.
249. Queitsch U, Hamann C, Schäffel F, Rellinghaus B, Schultz L, Blüher A & Mertig M (2009) Toward dense biotemplated magnetic nanoparticle arrays: probing the particle-template interaction. J Phys Chem C 113: 10471-10476.
250. Rachel R (2010) Cell envelopes of crenarchaeota and nanoarchaeota. Prokaryotic Cell Wall Compounds - Structure and Biochemistry, Vol. Chapter 9 (König H, Claus H & Varma A, eds), pp. 271-291. Springer, Heidelberg, Germany.
251. Reimhult E & Kumar K (2008) Membrane biosensor platforms using nano- and microporous supports. Trends Biotechnol 26: 82-89.
252. Remsen CC, Watson SW, Waterbury JB & Trüper HG (1968) Fine structure of Ectothiorhodospira mobilis Pelsh. J Bacteriol 95: 2374-2392.
253. Riedmann EM, Kyd JM, Smith AM, Gomez-Gallego S, Jalava K, Cripps AW & Lubitz W (2003) Construction of recombinant S-layer proteins (rSbsA) and their expression in bacterial ghosts-a delivery system for the nontypeable Haemophilus influenzae antigen Omp26. FEMS Immunol Med Microbiol 37: 185-192.
254. Ries W, Hotzy C, Schocher I, Sleytr UB & Sára M (1997) Evidence that the N-terminal part of the S-layer protein from Bacillus stearothermophilus PV72/p2 recognizes a secondary cell wall polymer. J Bacteriol 179: 3892-3898.
255. Ristl R, Steiner K, Zarschler K, Zayni S, Messner P & Schäffer C (2011) The S-layer glycome-adding to the sugar coat of bacteria. Int J Microbiol 2011: 127870.
256. Robards AW & Sleytr UB (1985) Freeze-fracture replication. Low Temperature Methods in Biological Electron Microscopy, Vol. 10 (Glauert AM, ed.), pp. 309-459. Elsevier, Amsterdam.
257. Roberts K, Grief C, Hills GJ & Shaw PJ (1985) Cell wall glycoproteins: structure and function. J Cell Sci Suppl 2: 105-127.
258. Rothbauer M, Kupcu S, Sticker D, Sleytr UB & Ertl P (2013) Exploitation of S-Layer Anisotropy: pH-Dependent Nanolayer Orientation for Cellular Micropatterning. ACS Nano 7: 8020-8030.
259. Rünzler D, Huber C, Moll D, Köhler G & Sára M (2004) Biophysical characterization of the entire bacterial surface layer protein SbsB and its two distinct functional domains. J Biol Chem 279: 5207-5215.
260. Salamitou S, Raynaud O, Lemaire M, Coughlan M, Beguin P & Aubert JP (1994a) Recognition specificity of the duplicated segments present in Clostridium thermocellum endoglucanase CelD and in the cellulosome-integrating protein CipA. J Bacteriol 176: 2822-2827.
261. Salamitou S, Lemaire M, Fujino T, Ohayon H, Gounon P, Beguin P & Aubert JP (1994b) Subcellular localization of Clostridium thermocellum ORF3p, a protein carrying a receptor for the docking sequence borne by the catalytic components of the cellulosome. J Bacteriol 176: 2828-2834.
262. Sára M & Sleytr UB (1987a) Charge distribution on the S layer of Bacillus stearothermophilus NRS 1536/3c and importance of charged groups for morphogenesis and function. J Bacteriol 169: 2804-2809.
263. Sára M & Sleytr UB (1987b) Molecular sieving through S layers of Bacillus stearothermophilus strains. J Bacteriol 169: 4092-4098.
264. Sára M & Sleytr UB (1987c) Production and characteristics of ultrafiltration membranes with uniform pores from two-dimensional arrays of proteins. J Membr Sci 33: 27-49.
265. Sára M & Sleytr UB (1988) Membrane Biotechnology: two-dimensional Protein Crystals for Ultrafiltration Purposes. Biotechnology, Vol. 6b (Rehm HJ, ed.), pp. 615-636. VCH, Weinheim.
266. Sára M & Sleytr UB (1989) Use of regularly structured bacterial cell envelope layers as matrix for the immobilization of macromolecules. Appl Microbiol Biotechnol 30: 184-189.
267. Sára M & Sleytr UB (1993) Relevance of charged groups for the integrity of the S-layer from Bacillus coagulans E38-66 and for molecular interactions. J Bacteriol 175: 2248-2254.
268. Sára M & Sleytr UB (1994) Comparative studies of S-layer proteins from Bacillus stearothermophilus strains expressed during growth in continuous culture under oxygen-limited and non-oxygen-limited conditions. J Bacteriol 176: 7182-7189.
269. Sára M, Kalsner I & Sleytr UB (1988a) Surface properties from the S-layer of Clostridium thermosaccharolyticum D120-70 and Clostridium thermohydrosulfuricum L111-69. Arch Microbiol 149: 527-533.
270. Sára M, Manigley C, Wolf G & Sleytr UB (1988b) Isoporous ultrafiltration membranes from bacterial cell envelope layers. J Membr Sci 36: 179-186.
271. Sára M, Küpcü S & Sleytr UB (1989) Localization of the carbohydrate residue of the S-layer glycoprotein from Clostridium thermohydrosulfuricum L111-69. Arch Microbiol 151: 416-420.
272. Sára M, Moser-Thier K, Kainz U & Sleytr UB (1990) Characterization of S-layers from mesophilic Bacillaceae and studies on their protective role towards muramidases. Arch Microbiol 153: 209-214.
273. Sára M, Pum D & Sleytr UB (1992) Permeability and charge-dependent adsorption properties of the S-layer lattice from Bacillus coagulans E38-66. J Bacteriol 174: 3487-3493.
274. Sára M, Küpcü S, Weiner C, Weigert S & Sleytr UB (1993) S-layers as immobilization and affinity matrices. Advances in Bacterial Paracrystalline Surface Layers, Vol. 252 (Beveridge TJ & Koval SF, eds), pp. 195-204. Plenum Press, New York & London.
275. Sára M, Küpcü S & Sleytr UB (1996a) Biotechnological applications of S-layers. Crystalline Bacterial Cell Surface Proteins (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 133-159. R. G. Landes Company and Academic Press, Inc., Austin, TX.
276. Sára M, Kuen B, Mayer HF, Mandl F, Schuster KC & Sleytr UB (1996b) Dynamics in oxygen-induced changes in S-layer protein synthesis from Bacillus stearothermophilus PV72 and the S-layer-deficient variant T5 in continuous culture and studies of the cell wall composition. J Bacteriol 178: 2108-2117.
277. Sára M, Egelseer EM, Dekitsch C & Sleytr UB (1998) Identification of two binding domains, one for peptidoglycan and another for a secondary cell wall polymer, on the N-terminal part of the S-layer protein SbsB from Bacillus stearothermophilus PV72/p2. J Bacteriol 180: 6780-6783.
278. Sára M, Pum D, Huber C, Ilk N, Pleschberger M & Sleytr UB (2006a) Nanoscale patterning of S-layer proteins as a natural self-assembly system. Biological and Pharmaceutical Nanomaterials Nanotechnologies for the Life Sciences, Vol. 2 (Kumar C, ed.), pp. 219-252. Wiley-VCH, Weinheim, Germany.
279. Sára M, Egelseer EM, Huber C, Ilk N, Pleschberger M, Pum D & Sleytr UB (2006b) S-layer proteins: potential application in nano(bio)technology. Microbial Bionanotechnology: Biological Self-Assembly Systems and Biopolymer-Based Nanostructures (Bernd Rehm MU, ed.), pp. 307-338. Horizon Bioscience, Palmerston North, New Zealand.
280. Saxton WO & Baumeister W (1982) The correlation averaging of a regularly arranged bacterial cell envelope protein. J Microsc 127: 127-138.
281. Saxton WO, Baumeister W & Hahn M (1984) Three-dimensional reconstruction of imperfect two-dimensional crystals. Ultramicroscopy 13: 57-70.
282. Schäffer C & Messner P (2004) Surface-layer glycoproteins: an example for the diversity of bacterial glycosylation with promising impacts on nanobiotechnology. Glycobiology 14: 31R-42R.
283. Schäffer C, Kählig H, Christian R, Schulz G, Zayni S & Messner P (1999) The diacetamidodideoxyuronic-acid-containing glycan chain of Bacillus stearothermophilus NRS 2004/3a represents the secondary cell-wall polymer of wild-type B. stearothermophilus strains. Microbiology 145: 1575-1583.
284. Schäffer C, Novotny R, Küpcü S, Zayni S, Scheberl A, Friedmann J, Sleytr UB & Messner P (2007) Novel biocatalysts based on S-layer self-assembly of Geobacillus stearothermophilus NRS 2004/3a: a nanobiotechnological approach. Small 3: 1549-1559.
285. Scherrer R & Gerhard P (1971) Molecular sieving by the Bacillus megatherium cell wall and protoplast. J Bacteriol 107: 718-735.
286. Scholz H, Hummel S, Witte A, Lubitz W & Kuen B (2000) The transposable element IS4712 prevents S-layer gene (sbsA) expression in Bacillus stearothermophilus and also affects the synthesis of altered surface layer proteins. Arch Microbiol 174: 97-103.
287. Scholz HC, Riedmann E, Witte A, Lubitz W & Kuen B (2001) S-layer variation in Bacillus stearothermophilus PV72 is based on DNA rearrangements between the chromosome and the naturally occurring megaplasmids. J Bacteriol 183: 1672-1679.
288. Schrems A, Kibrom A, Küpcü S, Kiene E, Sleytr UB & Schuster B (2011a) Bilayer lipid membrane formation on a chemically modified S-layer lattice. Langmuir 27: 3731-3738.
289. Schrems A, Larisch VD, Stanetty C, Dutter K, Damiati S, Sleytr UB & Schuster B (2011b) Liposome fusion on proteinaceous S-layer lattices triggered via b-diketone ligand-europium(III) complex formation. Soft Matter 7: 5514-5518.
290. Schrems A, Larisch VD, Sleytr UB, Hohenegger M, Lohner K & Schuster B (2013) Insertion of an anionic analogue of the antimicrobial peptide PGLa in lipid architectures including S-layer supported lipid bilayers. Curr Nanosci 9: 262-270.
291. Schultze-Lam S & Beveridge TJ (1994a) Physicochemical characteristics of the mineral-forming S-layer from the cyanobacterium Synechococcus strain GL24. Can J Microbiol 40: 216-233.
292. Schultze-Lam S & Beveridge TJ (1994b) Nucleation of celestite and strontianite on a cyanobacterial S-layer. Appl Environ Microbiol 60: 447-453.
293. Schultze-Lam S, Harauz G & Beveridge TJ (1992) Participation of a cyanobacterial S-layer in fine-grain mineral formation. J Bacteriol 174: 7971-7981.
294. Schuster B (2005) Biomimetic design of nano-patterned membranes. NanoBiotechnology 1: 153-164.
295. Schuster B & Sleytr UB (2000) S-layer-supported lipid membranes. J Biotechnol 74: 233-254.
296. Schuster B & Sleytr UB (2002a) The effect of hydrostatic pressure on S-layer-supported lipid membranes. Biochim Biophys Acta 1563: 29-34.
297. Schuster B & Sleytr UB (2002b) Single channel recordings of alpha-hemolysin reconstituted in S-layer-supported lipid bilayers. Bioelectrochemistry 55: 5-7.
298. Schuster B & Sleytr UB (2005) 2D-Protein Crystals (S-Layers) as Support for Lipid Membranes. Advances in Planar Lipid Bilayers and Liposomes, Vol. 1 (Tien TH & Ottova A, eds), pp. 247-293. Elsevier Science, Amsterdam, The Netherlands.
299. Schuster B & Sleytr UB (2006) Biomimetic S-layer supported lipid membranes. Curr Nanosci 2: 143-152.
300. Schuster B & Sleytr UB (2009a) Tailor-made crystalline structures of truncated S-layer proteins on heteropolysaccharides. Soft Matter 5: 334-341.
301. Schuster B & Sleytr UB (2009b) Composite S-layer lipid structures. J Struct Biol 168: 207-216.
302. Schuster B & Sleytr UB (2013) Nanotechnology with S-Layer Proteins. Protein Nanotechnology: Protocols, Instrumentation and Applications, 2nd edn, Vol. 996 (Gerrard JA, ed.), pp. 153-175. Humana Press, Springer Science + Business Media, New York.
303. Schuster B, Pum D & Sleytr UB (1997) Planar supported lipid membranes. FEMS Microbiol Rev 20: 159-162.
304. Schuster B, Pum D & Sleytr UB (1998a) Voltage clamp studies on S-layer-supported tetraether lipid membranes. Biochim Biophys Acta 1369: 51-60.
305. Schuster B, Pum D, Braha O, Bayley H & Sleytr UB (1998b) Self-assembled α-hemolysin pores in an S-layer-supported lipid bilayer. Biochim Biophys Acta 1370: 280-288.
306. Schuster B, Sleytr UB, Diederich A, Bahr G & Winterhalter M (1999) Probing the stability of S-layer-supported planar lipid membranes. Eur Biophys J 28: 583-590.
307. Schuster B, Pum D, Sára M, Braha O, Bayley H & Sleytr UB (2001) S-layer ultrafiltration membranes: a new support for stabilizing functionalized lipid membranes. Langmuir 17: 499-503.
308. Schuster B, Gufler PC, Pum D & Sleytr UB (2003a) Interplay of phospholipase A2 with S-layer-supported lipid monolayers. Langmuir 19: 3393-3397.
309. Schuster B, Weigert S, Pum D, Sára M & Sleytr UB (2003b) New method for generating tetraether lipid membranes on porous supports. Langmuir 19: 2392-2397.
310. Schuster B, Gufler PC, Pum D & Sleytr UB (2004) S-layer proteins as supporting scaffoldings for functional lipid membranes. IEEE Trans Nanobioscience 3: 16-21.
311. Schuster B, Györvary E, Pum D & Sleytr UB (2005) Nanotechnology with S-layer proteins. Methods Mol Biol 300: 101-123.
312. Schuster B, Pum D, Sára M & Sleytr UB (2006) S-Layer proteins as key components of a versatile molecular construction kit for biomedical Nanotechnology. Mini Rev Med Chem 6: 909-920.
313. Schuster B, Pum D & Sleytr UB (2008) S-layer stabilized lipid membranes. Biointerphases 3: FA3-FA11.
314. Schuster B, Kepplinger C & Sleytr UB (2010) Biomimetic S-layer stabilized lipid membranes. Biomimetics in Biophysics: Model Systems, Experimental Techniques and Computation (Toca-Herrera JL, ed.), pp. 1-12. Research Signpost, Kerala, India.
315. Schuster D, Küpcü S, Belton DJ, Perry CC, Stöger-Pollach M, Sleytr UB & Pum D (2013) Construction of silica enhanced S-layer protein cages. Acta Biomater 9: 5689-5697.
316. Shenton W, Pum D, Sleytr UB & Mann S (1997) Synthesis of CdS superlattices using self-assembled bacterial S-layers. Nature 389: 585-587.
317. Shin SH, Chung S, Sanii B, Comolli LR, Bertozzi CR & De Yoreo JJ (2012) Direct observation of kinetic traps associated with structural transformations leading to multiple pathways of S-layer assembly. P Natl Acad Sci USA 109: 12968-12973.
318. Shin S-H, Comolli LR, Tscheliessnig R, Wang C, Nam KT, Hexemer A, Siegerist CE, De Yoreo JJ & Bertozzi CR (2013) Self-assembly of 'S-Bilayers', a step toward expanding the dimensionality of S-layer assemblies. ACS Nano 7: 4946-4953.
319. Simon B, Nomellini JF, Chiou P, Binale W, Thornton J, Smit J & Leong JA (2001) Recombinant vaccines against infectious hematopoietic necrosis virus: production line by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials. Dis Aquat Organ 44: 400-402.
320. Sleytr UB (1975) Heterologous reattachment of regular arrays of glycoproteins on bacterial surfaces. Nature 257: 400-402.
321. Sleytr UB (1976) Self-assembly of the hexagonally and tetragonally arranged subunits of bacterial surface layers and their reattachement to cell walls. J Ultrastruct Res 55: 360-377.
322. Sleytr UB (1978) Regular arrays of macromolecules on bacterial cell walls: structure, chemistry, assembly, and function. Int Rev Cytol 53: 1-62.
323. Sleytr UB & Beveridge TJ (1999) Bacterial S-layers. Trends Microbiol 7: 253-260.
324. Sleytr UB & Glauert AM (1975) Analysis of regular arrays of subunits on bacterial surfaces: evidence for a dynamic process of assembly. J Ultrastruct Res 50: 103-116.
325. Sleytr UB & Glauert AM (1976) Ultrastructure of the cell walls of two closely related clostridia that possess different regular arrays of surface subunits. J Bacteriol 126: 869-882.
326. Sleytr UB & Messner P (1983) Crystalline surface layers on bacteria. Annu Rev Microbiol 37: 311-339.
327. Sleytr UB & Messner P (1989) Self-assembly of crystalline bacterial cell surface layers (S-layers). Electron Microscopy of Subcellular Dynamics (Plattner H, ed.), pp. 13-31. CRC Press, Boca Raton, Florida.
328. Sleytr UB & Messner P (2009) Crystalline bacterial cell surface layers (S-layers). Encyclopedia of Microbiology, Vol. 1 (Schaechter M, ed.), pp. 89-98. Academic Press/Elsevier Science, San Diego.
329. Sleytr UB & Plohberger R (1980) The dynamic process of assembly of two-dimensional arrays of macromolecules on bacterial cell walls. Electron Microscopy at Molecular Dimensions (Baumeister W & Vogell W, eds), pp. 36-47. Springer-Verlag, Berlin, Heidelberg, New York.
330. Sleytr UB & Sára M (1986) Ultrafiltration membranes with uniform pores from crystalline bacterial cell envelope layers. Appl Microbiol Biotechnol 25: 83-90.
331. Sleytr UB & Sára M (1988) Structure with membranes having continuous pores. US Patent Number 4, 752, 395.
332. Sleytr UB & Sára M (1997) Bacterial and archaeal S-layer proteins: structure-function relationships and their biotechnological applications. Trends Biotechnol 15: 20-26.
333. Sleytr UB & Thorne KJ (1976) Chemical characterization of the regularly arranged surface layers of Clostridium thermosaccharolyticum and Clostridium thermohydrosulfuricum. J Bacteriol 126: 377-383.
334. Sleytr U, Adam H & Klaushofer H (1968) Die Feinstruktur der Zellwandoberfläche von zwei thermophilen Clostridienarten, dargestellt mit Hilfe der Gefrierätztechnik. Mikroskopie (Wien) 23: 1-10.
335. Sleytr UB, Adams H & Klaushofer H (1969) Die Feinstruktur der Konidien von Aspergillus niger, V. Tiegh., dargestellt mit Hilfe der Gefrierätztechnik. Mikroskopie 25: 320-331.
336. Sleytr UB, Sára M, Küpcü Z & Messner P (1986) Structural and chemical characterization of S-layers of selected strains of Bacillus stearothermophilus and Desulfotomaculum nigrificans. Arch Microbiol 146: 19-24.
337. Sleytr UB, Messner P & Pum D (1988a) Analysis of crystalline bacterial surface layers by freeze-etching, metal shadowing, negative staining and ultrathin sectioning. Electron Microsc in Microbiology, Vol. 20 (Mayer F, ed.), pp. 29-60. Academic Press, Ltd., London.
338. Sleytr UB, Messner P, Pum D & Sára M (1988b) Crystalline Bacterial Cell Surface Layers, pp. 193. Springer, Berlin.
339. Sleytr UB, Mundt W & Messner P (1989) Pharmazeutische Struktur mit an Proteinträgern gebundenen Wirkstoffen. EP O 306 473 B1.
340. Sleytr UB, Mundt W & Messner P (1991) Immunogenic composition containing ordered carriers. US Patent Nr 5, 043, 158.
341. Sleytr UB, Messner P, Pum D & Sára M (1993a) Crystalline bacterial cell surface layers. Mol Microbiol 10: 911-916.
342. Sleytr UB, Messner P, Pum D & Sára M (1993b) Immobilised Macromolecules: Application Potentials. Springer-Verlag, London, UK.
343. Sleytr UB, Messner P, Pum D & Sára M (1996a) Crystalline surface layers on eubacteria and archaeobacteria. Crystalline Bacterial Cell Surface Proteins (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 211-225. R. G. Landes Company and Academic Press, Inc., Austin, TX.
344. Sleytr UB, Messner P, Pum D & Sára M (1996b) Occurence, location, ultrastructure and morphogenesis of S layers. Crystalline Bacterial Cell Surface Proteins (S Layers) (Sleytr UB, Messner P, Pum D & Sára M, eds), pp. 5-33. R. G. Landes Company and Academic Press, Inc., Austin, TX.
345. Sleytr UB, Messner P, Pum D & Sára M (1999) Crystalline bacterial cell surface layers (S-layers): from supramolecular cell structure to biomimetics and nanotechnology. Angew Chem Int Ed 38: 1034-1054.
346. Sleytr UB, Sara M, Mader C, Schuster B & Unger FM (2000) Use of secondary cell wall polymer of procaryotic microorganisms. EP 1285003A1.
347. Sleytr UB, Pum D, Schuster B & Sára M (2001) Molecular nanotechnology and nanobiotechnology with two-dimensional protein crystals (S-layers). Nano-Surface Chemistry (Rosoff M, ed.), pp. 333-389. Marcel Dekker, New York, Basle.
348. Sleytr UB, Sára M, Pum D, Schuster B, Messner P & Schäffer C (2002) Self-assembly protein systems: microbial S-layers. Biopolymers Polyamides and Complex Proteinaceous Materials I, Vol. 1st edn. (Steinbüchel A & Fahnestock SR, eds), pp. 285-338. Wiley-VCH, Weinheim.
349. Sleytr UB, Pum D, Sára M & Schuster B (2004) Molecular nanotechnology and nanobiotechnology with 2-D protein crystals. Encylopedia of Nanoscience and Nanotechnology, Vol. 5 (Nalwa HS, ed.), pp. 693-702. Academic Press, San Diego.
350. Sleytr UB, Sára M, Pum D & Schuster B (2005) Crystalline bacterial cell surface layers (S-layers): a versatile self-assembly system. Supramolecular Polymers (Ciferri A, ed.), pp. 583-612. Taylor & Francis Group, Boca Raton.
351. Sleytr UB, Sara M, Mader C, Schuster B & Unger FM (2006) Use of secondary cell wall polymer of procaryotic microorganisms. US Patent Number 7, 125, 707 B2.
352. Sleytr UB, Egelseer EM, Ilk N, Pum D & Schuster B (2007a) S-layers as a basic building block in a molecular construction kit. FEBS J 274: 323-334.
353. Sleytr UB, Huber C, Ilk N, Pum D, Schuster B & Egelseer EM (2007b) S-Layers as a tool kit for nanobiotechnological applications. FEMS Microbiol Lett 267: 131-144.
354. Sleytr UB, Egelseer EM, Ilk N, Messner P, Schäffer C, Pum D & Schuster B (2010) Nanobiotechnological applications of S-layers. Prokaryotic Cell Wall Compounds - Structure and Biochemistry (König H, Claus H & Varma A, eds), pp. 459-481. Springer, Heidelberg, Germany.
355. Sleytr UB, Schuster B, Egelseer EM, Pum D, Horejs CM, Tscheliessnig R & Ilk N (2011) Nanobiotechnology with S-layer proteins as building blocks. Progress in Molecular Biology and Translational Science, Molecular Assembly in Natural and Engineered Systems, Vol. 103 (Howorka S, ed.), pp. 277-352. Elsevier Academic Press Inc., Burlington.
356. Sleytr UB, Pum D, Egelseer EM, Ilk N & Schuster B (2013) S-layer proteins. Handbook of Biofunctional Surfaces (Knoll W, ed.), pp. 507-568. Pan Stanford Publishing, Singapore.
357. Smarda J, Smajs D, Komrska J & Krzyzanek V (2002) S-layers on cell walls of cyanobacteria. Micron 33: 257-277.
358. Smibert RM (1978) The genus Campylobacter. Annu Rev Microbiol 32: 673-709.
359. Smit J & Agabian N (1982) Cell surface patterning and morphoGenesis; bioGenesis of a periodic surface array during Caulobacter development. J Cell Biol 95: 41-49.
360. Smit J & Todd WJ (1986) Colloidal gold labels for immunocytochemical analysis of microbes. Ultrastructure Techniques for Microorganisms (Aldrich HC & Todd WJ, eds), pp. 469-519. Plenum Press, New York.
361. Smit E, Oling F, Demel R, Martinez B & Pouwels PH (2001) The S-layer protein of Lactobacillus acidophilus ATCC 4356: identification and characterisation of domains responsible for S-protein assembly and cell wall binding. J Mol Biol 305: 245-257.
362. Smit E, Jager D, Martinez B, Tielen FJ & Pouwels PH (2002) Structural and functional analysis of the S-layer protein crystallisation domain of Lactobacillus acidophilus ATCC 4356: evidence for protein-protein interaction of two subdomains. J Mol Biol 324: 953-964.
363. Smith RH, Messner P, Lamontagne LR, Sleytr UB & Unger FM (1993) Induction of T-cell immunity to oligosaccharide antigens immobilized on crystalline bacterial surface layers (S-layers). Vaccine 11: 919-924.
364. Srinivasan N & Kumar S (2012) Ordered and disordered proteins as nanomaterial building blocks. Wiley Interdiscip Rev Nanomed Nanobiotechnol 4: 204-218.
365. Steinem C & Janshoff A (2010) Multicomponent membranes on solid substrates: interfaces for protein binding. Curr Opin Colloid Interface Sci 15: 479-488.
366. Steiner K, Hanreich A, Kainz B, Hitchen PG, Dell A, Messner P & Schäffer C (2008) Recombinant glycans on an S-layer self-assembly protein: a new dimension for nanopatterned biomaterials. Small 4: 1728-1740.
367. Stetter KO (1999) Extremophiles and their adaptation to hot environments. FEBS Lett 452: 22-25.
368. Stimson E, Virji M, Makepeace K et al. (1995) Meningococcal pilin: a glycoprotein substituted with digalactosyl 2, 4-diacetamido-2, 4, 6-trideoxyhexose. Mol Microbiol 17: 1201-1214.
369. Sturm E, Egelseer E, Sára M & Sleytr UB (1993) Can S-layers of Bacillaceae control the release of their own exoproteins? Advances in Bacterial Paracrystalline Surface Layers, Vol. 252 (Beveridge TJ & Koval SF, eds), pp. 297-301. Plenum Press, New York & London.
370. Sugawara M & Hirano A (2005) Design and application of planar bilayer lipid membranes containing biological ion channels for chemical sensing. Advances in Planar Lipid Bilayers and Liposomes, Vol. 1 (Ottova A & Tien TH, eds), pp. 221-245. Elsevier Science, Amsterdam, the Netherlands.
371. Sumper M, Berg E, Mengele R & Strobel I (1990) Primary structure and glycosylation of the S-layer protein of Haloferax volcanii. J Bacteriol 172: 7111-7118.
372. Szabo Z & Pohlschroder M (2012) Diversity and subcellular distribution of archaeal secreted proteins. Front Microbiol 3: 207.
373. Tang J, Ebner A, Huber C, Ilk N, Zhu R, Pastushenko V, Sara M & Hinterdorfer P (2007) High resolution atomic force microscopy imaging and single molecule force microscopy studies of S-layer-strep-tag I and S-layer-strep-tag II proteins. Biophys J Suppl S: 513A.
374. Tarlovsky Y, Fabian M, Solomaha E, Honsa E, Olson JS & Maresso AW (2013) A Bacillus anthracis S-layer homology protein that binds heme and mediates heme delivery to IsdC. J Bacteriol 192: 3503-3511.
375. Thomas S, Austin JW, McCubbin WD, Kay CM & Trust TJ (1992) Roles of structural domains in the morphology and surface anchoring of the tetragonal paracrystalline array of Aeromonas hydrophila. Biochemical characterization of the major structural domain. J Mol Biol 228: 652-661.
376. Thompson SA & Blaser MJ (2000) Pathogenesis of Campylobacter fetus infections. Campylobacter (Nachamkin I & Blaser MJ, eds), pp. 321-347. American Society for Microbiology, Washington, DC.
377. Thompson JB & Ferris FG (1990) Cyanobacterial precipitation of gypsum, calcite, and magnesite from natural alkaline lake water. Geology 18: 995-998.
378. Thornley MJ, Glauert AM & Sleytr UB (1974) Structure and assembly of bacterial surface layers composed of regular arrays of subunits. Philos Trans R Soc Lond B Biol Sci 268: 147-153.
379. Tiefenauer L & Demarche S (2012) Challenges in the development of functional assays of membrane proteins. Materials 5: 2205-2242.
380. Tien TH & Ottova-Leitmannova A (2000) Membrane Biophysics: As Viewed From Experimental Bilayer Lipid Membranes. Elsevier, Amsterdam.
381. Toca-Herrera JL, Krastev R, Bosio V, Küpcü S, Pum D, Fery A, Sára M & Sleytr UB (2005) Recrystallization of bacterial S-layers on flat polyelectrolyte surfaces and hollow polyelectrolyte capsules. Small 1: 339-348.
382. Trojanowicz M (2001) Miniaturized biochemical sensing devices based on planar lipid membranes. Fresenius J Anal Chem 372: 246-260.
383. Trust TJ, Kay WW & Ishiguro EE (1983) Cell surface hydrophobicity and macrophage association of Aeromonas salmonicida. Curr Microbiol 9: 315-318.
384. Tschiggerl H, Casey JL, Parisi K, Foley M & Sleytr UB (2008a) Display of a peptide mimotope on a crystalline bacterial cell surface layer (S-layer) lattice for diagnosis of Epstein-Barr virus infection. Bioconjug Chem 19: 860-865.
385. Tschiggerl H, Breitwieser A, de Roo G, Verwoerd T, Schäffer C & Sleytr UB (2008b) Exploitation of the S-layer self-assembly system for site directed immobilization of enzymes demonstrated for an extremophilic laminarinase from Pyrococcus furiosus. J Biotechnol 133: 403-411.
386. Tsuboi A, Uchihi R, Tabata R, Takahashi Y, Hashiba H, Sasaki T, Yamagata H, Tsukagoshi N & Udaka S (1986) Characterization of the genes coding for two major cell wall proteins from protein-producing Bacillus brevis 47: complete nucleotide sequence of the outer wall protein gene. J Bacteriol 168: 365-373.
387. Uchida M, Harada T, Enkhtuya J, Kusumoto A, Kobayashi Y, Chiba S, Shyaka A & Kawamoto K (2012) Protective effect of Bacillus anthracis surface protein EA1 against anthrax in mice. Biochem Biophys Res Commun 421: 323-328.
388. Ücisik MH, Kupcu S, Schuster B & Sleytr UB (2013a) Characterization of CurcuEmulsomes: nanoformulation for enhanced solubility and delivery of curcumin. J Nanobiotechnology 11: 37.
389. Ücisik MH, Kupcu S, Debreczeny M, Schuster B & Sleytr UB (2013b) S-layer coated emulsomes as potential nanocarriers. Small 9: 2895-2904.
390. Vadillo-Rodríguez V, Busscher HJ, Norde W, de Vries J & van der Mei HC (2004) Dynamic cell surface hydrophobicity of Lactobacillus strains with and without surface layer proteins. J Bacteriol 186: 6647-6650.
391. Velásquez L & Dussan J (2009) Biosorption and bioaccumulation of heavy metals on dead and living biomass of Bacillus sphaericus. J Hazard Mater 167: 713-716.
392. Viviani B, Gardoni F & Marinovich M (2007) Cytokines and neuronal ion channels in health and disease. Int Rev Neurobiol 82: 247-263.
393. Völkel D, Zimmermann K, Breitwieser A, Pable S, Glatzel M, Scheiflinger F, Schwarz HP, Sára M, Sleytr UB & Dorner F (2003) Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers. Transfusion 43: 1677-1682.
394. Völlenkle C, Weigert S, Ilk N, Egelseer E, Weber V, Loth F, Falkenhagen D, Sleytr UB & Sára M (2004) Construction of a functional S-layer fusion protein comprising an immunoglobulin G-binding domain for development of specific adsorbents for extracorporeal blood purification. Appl Environ Microbiol 70: 1514-1521.
395. Vyalikh DV, Danzenbächer S, Mertig M, Kirchner A, Pompe W, Dedkov YS & Molodtsov SL (2004) Electronic structure of regular bacterial surface layers. Phys Rev Lett 93: 238103.
396. Vyas SP, Subhedar R & Jain S (2006) Development and characterization of emulsomes for sustained and targeted delivery of an antiviral agent to liver. J Pharm Pharmacol 58: 321-326.
397. Walper SA, Anderson GP, Brozozog Lee PA, Glaven RH, Liu JL, Bernstein RD, Zabetakis D, Johnson L, Czarnecki JM & Goldman ER (2012) Rugged single domain antibody detection elements for Bacillus anthracis spores and vegetative cells. PLoS One 7: e32801.
398. Wang YT, Oh SY, Hendrickx AP, Lunderberg JM & Schneewind O (2013) Bacillus cereus G9241 S-layer assembly contributes to the pathogenesis of anthrax-like disease in mice. J Bacteriol 195: 596-605.
399. Weigert S & Sára M (1995) Surface modification of an ultrafiltration membrane with crystalline structure and studies on interactions with selected protein molecules. J Memb Sci 106: 147-159.
400. Weiner C, Sára M & Sleytr UB (1994a) Novel protein A affinity matrix prepared from two-dimensional protein crystals. Biotechnol Bioeng 43: 321-330.
401. Weiner C, Sára M, Dasgupta G & Sleytr UB (1994b) Affinity cross-flow filtration: purification of IgG with a novel protein A affinity matrix prepared from two-dimensional protein crystals. Biotechnol Bioeng 44: 55-65.
402. Wetzer B, Pfandler A, Györvary E, Pum D, Lösche M & Sleytr UB (1998) S-Layer reconstitution at phospholipid monolayers. Langmuir 14: 6899-6906.
403. Weygand M, Wetzer B, Pum D, Sleytr UB, Cuvillier N, Kjaer K, Howes PB & Losche M (1999) Bacterial S-layer protein coupling to lipids: X-ray reflectivity and grazing incidence diffraction studies. Biophys J 76: 458-468.
404. Weygand M, Schalke M, Howes PB, Kjaer K, Friedmann J, Wetzer B, Pum D, Sleytr UB & Lösche M (2000) Coupling of protein sheet crystals (S-layers) to phospholipid monolayers. J Mater Chem 10: 141-148.
405. Weygand M, Kjaer K, Howes PB, Wetzer B, Pum D, Sleytr UB & Lösche M (2002) Structural reorganization of phospholipid headgroups upon recrystallization of an S-layer lattice. J Phys Chem B 106: 5793-5799.
406. Whitman WB, Coleman DC & Wiebe WJ (1998) Prokaryotes: the unseen majority. P Natl Acad Sci USA 95: 6578-6583.
407. Wildhaber I & Baumeister W (1987) The cell envelope of Thermoproteus tenax: three-dimensional structure of the surface layer and its role in shape-maintainance. EMBO J 6: 1475-1480.
408. Wimley WC & Hristova K (2011) Antimicrobial Peptides; Successes, Challenges and Unanswered Questions. J Membr Biol 239: 27-34.