Recombinant vaccines against infectious hematopoietic necrosis virus: Production by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials

Diseases of Aquatic Organisms

Volumn 44, Issue 1, 2001, Pages 17-27

  Simon, B ^a   Nomellini, J ^a   Chiou, P ^a   Bingle, W ^a   Thornton, J ^a   Smit, J ^a   Leong, J A ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Caulobacter crescentus; Fish virus; IHNV; Infectious hematopoietic necrosis virus; Rhabdovirus; S layer; T cell epitopes; Type I secretion; Vaccines

Indexed keywords

AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CAULOBACTER CRESCENTUS; INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS; RAINBOW TROUT; RECOMBINANT VACCINE; SURVIVAL; TETANUS TOXIN; VACCINE PRODUCTION; VIRUS GLYCOPROTEIN;

ANIMALIA; BACTERIA (MICROORGANISMS); CAULOBACTER VIBRIOIDES; INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS; MAMMALIA; ONCORHYNCHUS MYKISS; RHABDOVIRIDAE; SALMONIDAE;

EID: 0035951383     PISSN: 01775103     EISSN: None     Source Type: Journal    
DOI: 10.3354/dao044017     Document Type: Article

References (37)

1. Genetic Immunization of rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis virus
2. Recombinant fusion peptides containing single or multiple repeats of a ubiquitous T-helper epitope are highly immunogenic
3. The Caulobacter crescentus paracrystalline S-layer protein is secreted by a ABC transporter (type I) secretion apparatus
4. Specific-purpose plasmid cloning vectors II. Broad host range, high copy number, RSF1010-derived vectors, and a host-vector system for gene cloning in Pseudomonas
5. High-level expression vectors for Caulobacter crescentus incorporating the transcription/translation initiation regions of the paracrystalline surface-layer-protein gene
6. Linker mutagenesis of the Caulobacter crescentus S-layer protein: Toward a definition of an N-terminal anchoring region and a C-terminal secretion signal and the potential for heterologous protein secretion
7. Cell-surface display of a Pseudomonas aeruginosa strain K pilin peptide within the paracrystalline S-layer of Caulobacter crescentus
8. Secretion of the Caulobacter crescentus S-layer protein: Further localization of the C-terminal secretion signal and its use for secretion of recombinant proteins
9. Infectious hematopoietic necrosis virus (IHNV)
10. Plaquing procedure for IHNV
11. Serological identification of infectious hematopoietic necrosis virus in fixed tissue culture cells by alkaline phosphatase immunocytochemistry
12. General principles of fish vaccination
13. IHNV persistently infects chinook salmon embryo cells
14. The glycoprotein of infectious hematopoietic necrosis virus elicits neutralizing antibody and protective responses
15. Comparison of representative strains of infectious hematopoietic necrosis virus by serological neutralization and cross-protection assays
16. Transformation of freshwater and marine Caulobacters by electroporation
17. Expression in Escherichia coli of an epitope of the glycoprotein of infectious hematopoietic necrosis virus against viral challenge
18. A rapid boiling method for the preparation of bacterial plasmids
19. Occurrence of different types of infectious hematopoietic necrosis virus in fish
20. Rapid and efficient cosmid cloning
21. Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity
22. Nucleotide sequence of a cDNA clone carrying the glycoprotein gene of infectious hematopoietic necrosis virus (IHNV), a fish rhabdovirus
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction
25. Viral vaccines for aquaculture
26. Fish vaccine antigens produced or delivered by recombinant DNA technologies
27. Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
28. Cloning of the major protein of the Caulobacter crescentus periodic surface layer: Detection and characterization of the cloned peptide by protein expression assays
29. Caulobacter crescentus pilin: Purification, chemical characterization and amino-terminal amino acid sequence of a structural protein regulated during development
30. The S-layer of Caulobacter crescentus: Three-dimensional image reconstruction and structure analysis by electron microscopy
31. Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination
32. The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers
33. Molecular filtration for recovery of waterborne viruses of fish
34. Epitope mapping and characterization of the infectious hematopoietic necrosis virus glycoprotein using fusion proteins synthesized in Escherichia coli