Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in rat heart through mineralocorticoid receptor blockade

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Martín Fernández, Beatriz ^a,b   De Las Heras, Natalia ^a   Valero Muñoz, María ^a   Ballesteros, Sandra ^a   Yao, Yi Zhou ^b   Stanton, Peter G ^b   Fuller, Peter J ^b   Lahera, Vicente ^a  

^a SCHOOL OF MEDICINE   (Spain)

^b HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE A; MESSENGER RNA; MINERALOCORTICOID ANTAGONIST; MINERALOCORTICOID RECEPTOR; PLANT EXTRACT; PROANTHOCYANIDIN; PROANTHOCYANIDIN RICH ALMOND SKIN EXTRACT; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SPIRONOLACTONE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; IMMEDIATE EARLY PROTEIN; PROTEIN SERINE THREONINE KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE;

ALMOND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CTGF GENE; DIASTOLIC DYSFUNCTION; DRUG ISOLATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEART DISEASE; HEART HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERTENSION; MALE; MMP2 GENE; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; TGF BETA GENE; TIMP2 GENE; TREATMENT OUTCOME; ANIMAL; CELL LINE; CHEMISTRY; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; GENETICS; HEART; METABOLISM; PRUNUS; WISTAR RAT;

RATTUS;

ALDOSTERONE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; HEART; HYPERTENSION; IMMEDIATE-EARLY PROTEINS; MALE; MINERALOCORTICOID RECEPTOR ANTAGONISTS; PLANT EXTRACTS; PROANTHOCYANIDINS; PROTEIN-SERINE-THREONINE KINASES; PRUNUS; RATS; RATS, WISTAR; RECEPTORS, MINERALOCORTICOID; SPIRONOLACTONE;

EID: 84908592859     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111104     Document Type: Article

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