메뉴 건너뛰기




Volumn 145, Issue 7, 2004, Pages 3153-3157

Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; COLLAGEN; CYCLOOXYGENASE 2; DEOXYCORTICOSTERONE; EPLERENONE; MINERALOCORTICOID ANTAGONIST; OSTEOPONTIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM CHLORIDE; STEROID;

EID: 3042647297     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0005     Document Type: Article
Times cited : (99)

References (33)
  • 2
    • 0027081410 scopus 로고
    • Mineralocorticoid excess, dietary sodium, and myocardial fibrosis
    • Brilla CG, Weber KT 1992 Mineralocorticoid excess, dietary sodium, and myocardial fibrosis. J Lab Clin Med 120:893-901
    • (1992) J Lab Clin Med , vol.120 , pp. 893-901
    • Brilla, C.G.1    Weber, K.T.2
  • 3
    • 0028290539 scopus 로고
    • Mineralocorticoids, hypertension, and cardiac fibrosis
    • Young M, Fullerton M, Dilley R, Funder J 1994 Mineralocorticoids, hypertension, and cardiac fibrosis. J Clin Invest 93:2578-2583
    • (1994) J Clin Invest , vol.93 , pp. 2578-2583
    • Young, M.1    Fullerton, M.2    Dilley, R.3    Funder, J.4
  • 4
    • 0027227646 scopus 로고
    • Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism
    • Brilla CG, Matsubara LS, Weber KT 1993 Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism. J Mol Cell Cardiol 25:563-575
    • (1993) J Mol Cell Cardiol , vol.25 , pp. 563-575
    • Brilla, C.G.1    Matsubara, L.S.2    Weber, K.T.3
  • 5
    • 0029805353 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system in experimental mineralocorticoid-salt-induced cardiac fibrosis
    • Young MJ, Funder JW 1996 The renin-angiotensin-aldosterone system in experimental mineralocorticoid-salt-induced cardiac fibrosis. Am J Physiol 271:E883-E888
    • (1996) Am J Physiol , vol.271
    • Young, M.J.1    Funder, J.W.2
  • 6
    • 0029863964 scopus 로고    scopus 로고
    • Mineralocorticoids, salt, hypertension: Effects on the heart
    • Young MJ, Funder JW 1996 Mineralocorticoids, salt, hypertension: effects on the heart. Steroids 61:233-235
    • (1996) Steroids , vol.61 , pp. 233-235
    • Young, M.J.1    Funder, J.W.2
  • 8
    • 0029098580 scopus 로고
    • Temporal differences in fibroblast proliferation and phenotype expression in response to chronic administration of angiotensin II or aldosterone
    • Campbell SE, Janicki JS, Weber KT 1995 Temporal differences in fibroblast proliferation and phenotype expression in response to chronic administration of angiotensin II or aldosterone. J Mol Cell Cardiol 27:1545-1560
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 1545-1560
    • Campbell, S.E.1    Janicki, J.S.2    Weber, K.T.3
  • 9
    • 0037373553 scopus 로고    scopus 로고
    • Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: Effects of 11β-hydroxysteroid dehydrogenase inactivation
    • Young MJ, Moussa L, Dilley R, Funder JW 2003 Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11β-hydroxysteroid dehydrogenase inactivation. Endocrinology 144:1121-1125
    • (2003) Endocrinology , vol.144 , pp. 1121-1125
    • Young, M.J.1    Moussa, L.2    Dilley, R.3    Funder, J.W.4
  • 10
    • 0034920217 scopus 로고    scopus 로고
    • Experimental cardiac fibrosis: Differential time course of responses to mineralocorticoid-salt administration
    • Fujisawa G, Dilley R, Fullerton MJ, Funder JW 2001 Experimental cardiac fibrosis: differential time course of responses to mineralocorticoid-salt administration. Endocrinology 142:3625-3631
    • (2001) Endocrinology , vol.142 , pp. 3625-3631
    • Fujisawa, G.1    Dilley, R.2    Fullerton, M.J.3    Funder, J.W.4
  • 12
    • 0031600240 scopus 로고    scopus 로고
    • Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats
    • Rocha R, Chander PN, Khanna K, Zuckerman A, Stier Jr CT 1998 Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 31:451-458
    • (1998) Hypertension , vol.31 , pp. 451-458
    • Rocha, R.1    Chander, P.N.2    Khanna, K.3    Zuckerman, A.4    Stier Jr., C.T.5
  • 13
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES)
    • Rales Investigators
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B 2000 Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Rales Investigators. Circulation 102:2700-2706
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 14
    • 0037016007 scopus 로고    scopus 로고
    • Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure
    • Suzuki G, Morita H, Mishima T, Sharov VG, Todor A, Tanheco EJ, Rudolph AE, McMahon EG, Goldstein S, Sabbah HN 2002 Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure. Circulation 106:2967-2972
    • (2002) Circulation , vol.106 , pp. 2967-2972
    • Suzuki, G.1    Morita, H.2    Mishima, T.3    Sharov, V.G.4    Todor, A.5    Tanheco, E.J.6    Rudolph, A.E.7    McMahon, E.G.8    Goldstein, S.9    Sabbah, H.N.10
  • 15
    • 0032951864 scopus 로고    scopus 로고
    • Reversal of cardiac fibrosis in deoxycorticosterone acetate-salt hypertensive rats by inhibition of the renin-angiotensin system
    • Brown L, Duce B, Miric G, Sernia C 1999 Reversal of cardiac fibrosis in deoxycorticosterone acetate-salt hypertensive rats by inhibition of the renin-angiotensin system. J Am Soc Nephrol 10(Suppl 11):S143-S148
    • (1999) J Am Soc Nephrol , vol.10 , Issue.11 SUPPL.
    • Brown, L.1    Duce, B.2    Miric, G.3    Sernia, C.4
  • 16
    • 0031790731 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of heart failure
    • Ball AM, Sole MJ 1998 Oxidative stress and the pathogenesis of heart failure. Cardiol Clin 16:665-675, viii-ix
    • (1998) Cardiol Clin , vol.16 , pp. 665-675
    • Ball, A.M.1    Sole, M.J.2
  • 17
    • 0036665229 scopus 로고    scopus 로고
    • Oxidative stress, nitric oxide, and vascular disease
    • Jeremy JY, Yim AP, Wan S, Angelini GD 2002 Oxidative stress, nitric oxide, and vascular disease. J Card Surg 17:324-327
    • (2002) J Card Surg , vol.17 , pp. 324-327
    • Jeremy, J.Y.1    Yim, A.P.2    Wan, S.3    Angelini, G.D.4
  • 18
    • 10744223948 scopus 로고    scopus 로고
    • Correlation of oxidative stress with activity of matrix metalloproteinase in patients with coronary artery disease. Possible role for left ventricular remodelling
    • Kameda K, Matsunaga T, Abe N, Hanada H, Ishizaka H, Ono H, Saitoh M, Fukui K, Fukuda I, Osanai T, Okumura K 2003 Correlation of oxidative stress with activity of matrix metalloproteinase in patients with coronary artery disease. Possible role for left ventricular remodelling. Eur Heart J 24:2180-2185
    • (2003) Eur Heart J , vol.24 , pp. 2180-2185
    • Kameda, K.1    Matsunaga, T.2    Abe, N.3    Hanada, H.4    Ishizaka, H.5    Ono, H.6    Saitoh, M.7    Fukui, K.8    Fukuda, I.9    Osanai, T.10    Okumura, K.11
  • 19
    • 0036089571 scopus 로고    scopus 로고
    • Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure
    • Sorescu D, Griendling KK 2002 Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congest Heart Fail 8:132-140
    • (2002) Congest Heart Fail , vol.8 , pp. 132-140
    • Sorescu, D.1    Griendling, K.K.2
  • 21
    • 0029661428 scopus 로고    scopus 로고
    • phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
    • phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem 271:23317-23321
    • (1996) J Biol Chem , vol.271 , pp. 23317-23321
    • Ushio-Fukai, M.1    Zafari, A.M.2    Fukui, T.3    Ishizaka, N.4    Griendling, K.K.5
  • 22
    • 0036841807 scopus 로고    scopus 로고
    • Aldosterone-induced inflammation in the rat heart: Role of oxidative stress
    • Sun Y, Zhang J, Lu L, Chen SS, Quinn MT, Weber KT 2002 Aldosterone-induced inflammation in the rat heart: role of oxidative stress. Am J Pathol 161:1773-1781
    • (2002) Am J Pathol , vol.161 , pp. 1773-1781
    • Sun, Y.1    Zhang, J.2    Lu, L.3    Chen, S.S.4    Quinn, M.T.5    Weber, K.T.6
  • 23
    • 0036841861 scopus 로고    scopus 로고
    • NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels
    • Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, Dominiczak AF 2002 NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension 40:755-762
    • (2002) Hypertension , vol.40 , pp. 755-762
    • Hamilton, C.A.1    Brosnan, M.J.2    Al-Benna, S.3    Berg, G.4    Dominiczak, A.F.5
  • 24
    • 0033781454 scopus 로고    scopus 로고
    • Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
    • Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M 2000 Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 20:2175-2183
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2175-2183
    • Griendling, K.K.1    Sorescu, D.2    Lassegue, B.3    Ushio-Fukai, M.4
  • 25
    • 0034126304 scopus 로고    scopus 로고
    • Effects of probucol on changes of antioxidant enzymes in adriamycin-induced cardiomyopathy in rats
    • Li T, Danelisen I, Bello-Klein A, Singal PK 2000 Effects of probucol on changes of antioxidant enzymes in adriamycin-induced cardiomyopathy in rats. Cardiovasc Res 46:523-530
    • (2000) Cardiovasc Res , vol.46 , pp. 523-530
    • Li, T.1    Danelisen, I.2    Bello-Klein, A.3    Singal, P.K.4
  • 26
    • 0034617071 scopus 로고    scopus 로고
    • phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ Res 87:26-32
    • (2000) Circ Res , vol.87 , pp. 26-32
    • Gorlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Dehghani, F.5    Busse, R.6
  • 27
    • 0033625558 scopus 로고    scopus 로고
    • Role of 11β-hydroxysteroid dehydrogenase in nongenomic aldosterone effects in human arteries
    • Alzamora R, Michea L, Marusic ET 2000 Role of 11β-hydroxysteroid dehydrogenase in nongenomic aldosterone effects in human arteries. Hypertension 35:1099-1104
    • (2000) Hypertension , vol.35 , pp. 1099-1104
    • Alzamora, R.1    Michea, L.2    Marusic, E.T.3
  • 28
    • 0041419403 scopus 로고    scopus 로고
    • Mineralocorticoid action and sodium-hydrogen exchange: Studies in experimental cardiac fibrosis
    • Young M, Funder J 2003 Mineralocorticoid action and sodium-hydrogen exchange: studies in experimental cardiac fibrosis. Endocrinology 144:3848-3851
    • (2003) Endocrinology , vol.144 , pp. 3848-3851
    • Young, M.1    Funder, J.2
  • 29
    • 0030444810 scopus 로고    scopus 로고
    • Exclusion of corticosterone from epithelial mineralocorticoid receptors is insufficient for selectivity of aldosterone action: In vivo binding studies
    • Funder J, Myles K 1996 Exclusion of corticosterone from epithelial mineralocorticoid receptors is insufficient for selectivity of aldosterone action: in vivo binding studies. Endocrinology 137:5264-5268
    • (1996) Endocrinology , vol.137 , pp. 5264-5268
    • Funder, J.1    Myles, K.2
  • 31
    • 0035943051 scopus 로고    scopus 로고
    • Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries
    • Ward MR, Kanellakis P, Ramsey D, Funder J, Bobik A 2001 Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. Circulation 104:467-472
    • (2001) Circulation , vol.104 , pp. 467-472
    • Ward, M.R.1    Kanellakis, P.2    Ramsey, D.3    Funder, J.4    Bobik, A.5
  • 32
    • 1942518234 scopus 로고    scopus 로고
    • Is aldosterone bad for the heart?
    • Funder JW 2004 Is aldosterone bad for the heart? Trends Endocrinol Metab 15:139-142
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 139-142
    • Funder, J.W.1
  • 33
    • 0348149133 scopus 로고    scopus 로고
    • The role of mineralocorticoid receptor antagonists in the treatment of cardiac failure
    • Funder JW 2003 The role of mineralocorticoid receptor antagonists in the treatment of cardiac failure. Expert Opin Invest Drugs 12:1963-1969
    • (2003) Expert Opin Invest Drugs , vol.12 , pp. 1963-1969
    • Funder, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.