Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 12, 2014, Pages 1672-1682

  Abdel Shakor, Abo Bakr ^a,b   Atia, Mona ^a   Ismail, Ismail Ahmed ^a,c   Alshehri, Ali ^b   El Refaey, Hesham ^b   Kwiatkowska, Katarzyna ^d   Sobota, Andrzej ^d  

^a Assiut University   (Egypt)

^b KING KHALID UNIVERSITY   (Saudi Arabia)

^c TAIBAH UNIVERSITY   (Saudi Arabia)

^d NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Apoptosis; Ceramide; Curcumin; HL60 cells; Multidrug resistance

Indexed keywords

3,3' (1,4 PHENYLENE)BIS[N [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL]ACRYLAMIDE]; CASPASE 3; CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; CURCUMIN; CYCLOSPORIN A; PROTEIN BAX; PROTEIN BCL 2; SPHINGOMYELIN PHOSPHODIESTERASE; GLUCOSYLTRANSFERASE; MULTIDRUG RESISTANCE PROTEIN; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL VIABILITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HL 60 CELL LINE; HUMAN; HUMAN CELL; LIPID STORAGE; MULTIDRUG RESISTANCE; BIOLOGICAL MODEL; CELL SURVIVAL; DRUG EFFECTS; DRUG RESISTANCE; ENZYMOLOGY; LEUKEMIA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL SURVIVAL; CERAMIDES; CURCUMIN; DOWN-REGULATION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; GLUCOSYLTRANSFERASES; HL-60 CELLS; HUMANS; LEUKEMIA; MODELS, BIOLOGICAL; P-GLYCOPROTEIN; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE; VINCRISTINE;

EID: 84908544681     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.09.006     Document Type: Article

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