Possible role of ceramide as an indicator of chemoresistance: Decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia

Clinical Cancer Research

Volumn 9, Issue 1 I, 2003, Pages 415-423

  Itoh, Mitsuru ^a   Kitano, Toshiyuki ^a   Watanabe, Mitsumasa ^a   Kondo, Tadakazu ^a   Yabu, Takeshi ^a   Taguchi, Yoshimitu ^a   Iwai, Kazuya ^a   Tashima, Masaro ^a   Uchiyama, Takashi ^a   Okazaki, Toshiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BLEOMYCIN; CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; CYCLOPHOSPHAMIDE; CYTARABINE; DACARBAZINE; DAUNORUBICIN; DOXORUBICIN; ENOCITABINE; ETOPOSIDE; HYDROXYUREA; IDARUBICIN; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; MITOXANTRONE; MULTIDRUG RESISTANT 1 PROTEIN; N ACETYLSPHINGOSINE; PIRARUBICIN; PREDNISOLONE; PROTEIN; PROTEIN BCL 2; SPHINGOMYELIN SYNTHASE; SPHINGOSINE DERIVATIVE; SYNTHETASE; UNCLASSIFIED DRUG; VINCRISTINE;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG UPTAKE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL LINE; CELL SEPARATION; CERAMIDES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; FLOW CYTOMETRY; GLUCOSYLTRANSFERASES; HL-60 CELLS; HUMANS; LEUKEMIA; MIDDLE AGED; NEOPLASMS; PROPIDIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPHINGOSINE; TRANSFECTION; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 12244284610     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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