Kinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites

Biophysical Journal

Volumn 107, Issue 9, 2014, Pages 2204-2213

  Scarabelli, Guido ^a   Grant, Barry J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; KIF11 PROTEIN, HUMAN; KINESIN; NUCLEOTIDE; PROTEIN BINDING;

ALLOSTERISM; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MICROTUBULE; MOLECULAR DYNAMICS; MOTION; MUTATION; PROTEIN CONFORMATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; BINDING SITES; HUMANS; KINESIN; MICROTUBULES; MOLECULAR DYNAMICS SIMULATION; MOTION; MUTATION; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84908544641     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2014.09.019     Document Type: Article

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