Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 5, 2014, Pages 1837-1842

  Goulet, Adeline ^a,d   Major, Jennifer ^b   Jun, Yonggun ^c   Gross, Steven P ^c   Rosenfeld, Steven S ^b   Moores, Carolyn A ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CNRS   (France)

Author keywords

Cancer; Macromolecular assemblies; Mitosis; Molecular motors

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; KINESIN 5;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYOELECTRON MICROSCOPY; ENZYME CONFORMATION; ENZYME STRUCTURE; HYDROLYSIS; MICROTUBULE; MITOSIS; PRIORITY JOURNAL;

CANCER; MACROMOLECULAR ASSEMBLIES; MITOSIS; MOLECULAR MOTORS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; KINESIN; KINETICS; MICROTUBULES; MITOSIS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84893496828     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1319848111     Document Type: Article

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