Real-time structural transitions are coupled to chemical steps in ATP hydrolysis by Eg5 kinesin

Journal of Biological Chemistry

Volumn 285, Issue 15, 2010, Pages 11073-11077

  Jun, Bokkyoo ^a   Kim, Sunyoung ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; BIOCHEMICAL LEVEL; BIOLOGICAL REACTION; BOND CLEAVAGES; BOUND STATE; CATALYTIC BASE; CATALYTIC CYCLES; CHEMICAL ENERGY; CONFORMATIONAL SWITCHING; CONTINUOUS OBSERVATION; DRIVE FORCE; ENERGY TRANSDUCTION; IN-VITRO; INORGANIC PHOSPHATES; KEY ELEMENTS; KINESINS; LEAVING GROUPS; MECHANICAL MOTIONS; MECHANOCHEMICALS; MOTOR DOMAIN; MOTOR PROTEINS; PROTON ABSTRACTION; SPECTRAL MARKERS; STRUCTURAL MODIFICATIONS; STRUCTURAL TRANSITIONS; TWO STAGE; UV PHOTOLYSIS;

CHEMICAL BONDS; CHEMICAL ELEMENTS; CONFORMATIONS; COORDINATION REACTIONS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROLYSIS; PHOTOLYSIS; PROTEINS;

AUTOMOBILE EXHIBITIONS;

ADENOSINE TRIPHOSPHATE; KINESIN 5; PHOSPHATE; WATER;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ESCHERICHIA COLI; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN MODIFICATION; ULTRAVIOLET RADIATION; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BIOCHEMISTRY; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROLYSIS; KINESIN; PHOSPHATES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 77951221121     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C110.103762     Document Type: Article

References (32)

1. Vale, R. D. (1996) J. Cell Biol. 135, 291-302
2. Wojcik, E. J., Dalrymple, N. A., Alford, S. R., Walker, R. A., and Kim, S. (2004) Biochemistry 43, 9939-9949
3. Du, X., Frei, H., and Kim, S. H. (2000) J. Biol. Chem. 275, 8492-8500
4. Allin, C., and Gerwert, K. (2001) Biochemistry 40, 3037-3046
5. Liu, M., and Barth, A. (2002) Biopolymers. 67, 267-270
6. White, E. M., Holland, A. R., and MacDonald, G. (2008) Biochemistry 47, 84-91
7. Braiman, M. S., Ahl, P. L., and Rothschild, K. J. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 5221-5225
8. Learman, S. S., Kim, C. D., Stevens, N. S., Kim, S., Wojcik, E. J., and Walker, R. A. (2009) Biochemistry 48, 1754-1762
9. Cepus, V., Ulbrich, C., Allin, C., Troullier, A., and Gerwert, K. (1998) Methods Enzymol. 291, 223-245
10. Barth, A., von Germar, F., Kreutz, W., and Mäntele, W. (1996) J. Biol. Chem. 271, 30637-30646
11. Cochran, J. C., Gatial, J. E., 3rd, Kapoor, T. M., and Gilbert, S. P. (2005) J. Biol. Chem. 280, 12658-12667
12. Maliga, Z., Kapoor, T. M., and Mitchison, T. J. (2002) Chem. Biol. 9, 989-996
13. DeBonis, S., Simorre, J. P., Crevel, I., Lebeau, L., Skoufias, D. A., Blangy, A., Ebel, C., Gans, P., Cross, R., Hackney, D. D., Wade, R. H., and Kozielski, F. (2003) Biochemistry 42, 338-349
14. Yan, Y., Sardana, V., Xu, B., Homnick, C., Halczenko, W., Buser, C. A., Schaber, M., Hartman, G. D., Huber, H. E., and Kuo, L. C. (2004) J. Mol. Biol. 335, 547-554
15. Asmis, K. R., Pivonka, N. L., Santambrogio, G., Brümmer, M., Kaposta, C., Neumark, D. M., and Wöste, L. (2003) Science 299, 1375-1377
16. Parke, C. L., Wojcik, E. J., Kim, S., and Worthylake, D. K. (2010) J. Biol. Chem. 285, 5859-5867
17. Cheng, H., Nikolic-Hughes, I., Wang, J. H., Deng, H., O'Brien, P. J., Wu, L., Zhang, Z. Y., Herschlag, D., and Callender, R. (2002) J. Am. Chem. Soc. 124, 11295-11306
18. Krimm, S., and Bandekar, J. (1986) in Advances in Protein Chemistry (Anfinsen, C. B., Edsall, J. T., and Richards, F. M., eds), pp 181-364, Academic Press, New York
19. Surewicz, W. K., Mantsch, H. H., and Chapman, D. (1993) Biochemistry 32, 389-394
20. Jackson, M., and Mantsch, H. H. (1995) Crit. Rev. Biochem. Mol. Biol. 30, 95-120
21. Goormaghtigh, E., Cabiaux, V., and Ruysschaert, J. M. (1994) Subcell. Biochem. 23, 329-362
22. Prestrelski, S. J., Byler, D. M., and Thompson, M. P. (1991) Int. J. Peptide Protein Res. 37, 508-512
23. Barth, A., and Zscherp, C. (2002) Q. Rev. Biophys. 35, 369-430
24. Fabian, H., and Schultz, C. P. (2000) in Encyclopedia of Analytical Chemistry (Meyers, R. A., ed) pp 5779-5803, John Wiley & Sons Ltd., Chichester, UK
25. Li, G., and Cui, Q. (2004) J. Phys. Chem. B. 108, 3342-3357
26. Ahmad, Z., and Senior, A. E. (2004) J. Biol. Chem. 279, 46057-46064
27. Dittrich, M., Hayashi, S., and Schulten, K. (2004) Biophys. J. 87, 2954-2967
28. Scheidig, A. J., Burmester, C., and Goody, R. S. (1999) Structure 7, 1311-1324
29. Garczarek, F., and Gerwert, K. (2006) Nature 439, 109-112
30. Mathias, G., and Marx, D. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 6980-6985
31. Baer, M., Mathias, G., Kuo, I. F., Tobias, D. J., Mundy, C. J., and Marx, D. (2008) Chemphyschem 9, 2703-2707
32. Turner, J., Anderson, R., Guo, J., Beraud, C., Fletterick, R., and Sakowicz, R. (2001) J. Biol. Chem. 276, 25496-25502