메뉴 건너뛰기




Volumn 63, Issue 10, 2014, Pages 1587-1595

ClC-3 chloride channel/antiporter defect contributes to inflammatory bowel disease in humans and mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CHLORIDE CHANNEL; CLC 3 PROTEIN; DEXTRAN SULFATE; POLYPEPTIDE ANTIBIOTIC AGENT; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1; CLC 3 CHANNEL; CLC-3 CHANNEL;

EID: 84908540197     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-305168     Document Type: Article
Times cited : (46)

References (45)
  • 2
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy KJ, Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011;474:298-306.
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 3
    • 33847381116 scopus 로고    scopus 로고
    • The fundamental basis of inflammatory bowel disease
    • Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 2007;117:514-21.
    • (2007) J Clin Invest , vol.117 , pp. 514-521
    • Strober, W.1    Fuss, I.2    Mannon, P.3
  • 4
    • 0030053385 scopus 로고    scopus 로고
    • Unifying hypothesis for inflammatory bowel disease and associated colon cancer: Sticking the pieces together with sugar
    • Rhodes JM. Unifying hypothesis for inflammatory bowel disease and associated colon cancer: sticking the pieces together with sugar. Lancet 1996;347:40-4.
    • (1996) Lancet , vol.347 , pp. 40-44
    • Rhodes, J.M.1
  • 5
    • 0242678327 scopus 로고    scopus 로고
    • Increased enterocyte apoptosis in inflamed areas of Crohn's disease
    • Di Sabatino A, Ciccocioppo R, Luinetti O, et al. Increased enterocyte apoptosis in inflamed areas of Crohn's disease. Dis Colon Rectum 2003;46:1498-507.
    • (2003) Dis Colon Rectum , vol.46 , pp. 1498-1507
    • Di Sabatino, A.1    Ciccocioppo, R.2    Luinetti, O.3
  • 6
    • 28144437207 scopus 로고    scopus 로고
    • Paneth cells: Their role in innate immunity and inflammatory disease
    • Elphick DA, Mahida YR. Paneth cells: their role in innate immunity and inflammatory disease. Gut 2005;54:1802-9.
    • (2005) Gut , vol.54 , pp. 1802-1809
    • Elphick, D.A.1    Mahida, Y.R.2
  • 7
    • 59849113041 scopus 로고    scopus 로고
    • The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF
    • Frey MR, Edelblum KL, Mullane MT, et al. The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF. Gastroenterology 2009;136:217-26.
    • (2009) Gastroenterology , vol.136 , pp. 217-226
    • Frey, M.R.1    Edelblum, K.L.2    Mullane, M.T.3
  • 8
    • 80052845560 scopus 로고    scopus 로고
    • Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
    • Gunther C, Martini E, Wittkopf N, et al. Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 2011;477:335-9.
    • (2011) Nature , vol.477 , pp. 335-339
    • Gunther, C.1    Martini, E.2    Wittkopf, N.3
  • 9
    • 0036064749 scopus 로고    scopus 로고
    • Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery
    • Hagiwara C, Tanaka M, Kudo H. Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery. J Gastroenterol Hepatol 2002;17:758-64.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 758-764
    • Hagiwara, C.1    Tanaka, M.2    Kudo, H.3
  • 10
    • 34047173496 scopus 로고    scopus 로고
    • Epithelial NEMO links innate immunity to chronic intestinal inflammation
    • Nenci A, Becker C, Wullaert A, et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 2007;446:557-61.
    • (2007) Nature , vol.446 , pp. 557-561
    • Nenci, A.1    Becker, C.2    Wullaert, A.3
  • 11
    • 79955501236 scopus 로고    scopus 로고
    • PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
    • Qiu W, Wu B, Wang X, et al. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest 2011;121:1722-32.
    • (2011) J Clin Invest , vol.121 , pp. 1722-1732
    • Qiu, W.1    Wu, B.2    Wang, X.3
  • 12
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • Vaishnava S, Behrendt CL, Ismail AS, et al. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci USA 2008;105:20858-63.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3
  • 14
    • 0031456376 scopus 로고    scopus 로고
    • Molecular identification of a volume-regulated chloride channel
    • Duan D, Winter C, Cowley S, et al. Molecular identification of a volume-regulated chloride channel. Nature 1997;390:417-21.
    • (1997) Nature , vol.390 , pp. 417-421
    • Duan, D.1    Winter, C.2    Cowley, S.3
  • 15
    • 77951782126 scopus 로고    scopus 로고
    • Chloride channels: Often enigmatic, rarely predictable
    • Duran C, Thompson CH, Xiao Q, et al. Chloride channels: often enigmatic, rarely predictable. Annu Rev Physiol 2010;72:95-121.
    • (2010) Annu Rev Physiol , vol.72 , pp. 95-121
    • Duran, C.1    Thompson, C.H.2    Xiao, Q.3
  • 16
    • 14844290889 scopus 로고    scopus 로고
    • - concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells
    • - concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells. J Biol Chem 2005;280:7301-8.
    • (2005) J Biol Chem , vol.280 , pp. 7301-7308
    • Zhou, J.G.1    Ren, J.L.2    Qiu, Q.Y.3
  • 17
    • 84873690749 scopus 로고    scopus 로고
    • Chloride in vesicular trafficking and function
    • Stauber T, Jentsch TJ. Chloride in vesicular trafficking and function. Annu Rev Physiol 2013;75:453-77.
    • (2013) Annu Rev Physiol , vol.75 , pp. 453-477
    • Stauber, T.1    Jentsch, T.J.2
  • 18
    • 79551502232 scopus 로고    scopus 로고
    • A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation
    • Chu X, Filali M, Stanic B, et al. A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation. Arterioscler Thromb Vasc Biol 2011;31:345-51.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 345-351
    • Chu, X.1    Filali, M.2    Stanic, B.3
  • 19
    • 70349484215 scopus 로고    scopus 로고
    • The granular chloride channel ClC-3 is permissive for insulin secretion
    • Deriy LV, Gomez EA, Jacobson DA, et al . The granular chloride channel ClC-3 is permissive for insulin secretion. Cell Metab 2009;10:316-23.
    • (2009) Cell Metab , vol.10 , pp. 316-323
    • Deriy, L.V.1    Gomez, E.A.2    Jacobson, D.A.3
  • 20
    • 33744907004 scopus 로고    scopus 로고
    • - channel in cell volume regulation, proliferation and apoptosis in vascular smooth muscle cells
    • - channel in cell volume regulation, proliferation and apoptosis in vascular smooth muscle cells. Trends Pharmacol Sci 2006;27:290-6.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 290-296
    • Guan, Y.Y.1    Wang, G.L.2    Zhou, J.G.3
  • 21
    • 55249114962 scopus 로고    scopus 로고
    • ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells
    • Habela CW, Olsen ML, Sontheimer H. ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells. J Neurosci 2008;28:9205-17.
    • (2008) J Neurosci , vol.28 , pp. 9205-9217
    • Habela, C.W.1    Olsen, M.L.2    Sontheimer, H.3
  • 22
    • 13244277880 scopus 로고    scopus 로고
    • Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
    • Maeda S, Hsu LC, Liu H, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 2005;307:734-8.
    • (2005) Science , vol.307 , pp. 734-738
    • Maeda, S.1    Hsu, L.C.2    Liu, H.3
  • 23
    • 79955788115 scopus 로고    scopus 로고
    • ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway
    • Qian Y, Du YH, Tang YB, et al. ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway. Apoptosis 2011;16:468-77.
    • (2011) Apoptosis , vol.16 , pp. 468-477
    • Qian, Y.1    Du, Y.H.2    Tang, Y.B.3
  • 24
    • 79953206228 scopus 로고    scopus 로고
    • Presynaptic CLC-3 determines quantal size of inhibitory transmission in the hippocampus
    • Riazanski V, Deriy LV, Shevchenko PD, et al. Presynaptic CLC-3 determines quantal size of inhibitory transmission in the hippocampus. Nat Neurosci 2011;14:487-94.
    • (2011) Nat Neurosci , vol.14 , pp. 487-494
    • Riazanski, V.1    Deriy, L.V.2    Shevchenko, P.D.3
  • 25
    • 17744375755 scopus 로고    scopus 로고
    • Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus
    • Stobrawa SM, Breiderhoff T, Takamori S, et al . Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Neuron 2001;29:185-96.
    • (2001) Neuron , vol.29 , pp. 185-196
    • Stobrawa, S.M.1    Breiderhoff, T.2    Takamori, S.3
  • 26
    • 83755225789 scopus 로고    scopus 로고
    • Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning
    • Bozeat ND, Xiang SY, Ye LL, et al. Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning. Cell Physiol Biochem 2011;28:1265-78.
    • (2011) Cell Physiol Biochem , vol.28 , pp. 1265-1278
    • Bozeat, N.D.1    Xiang, S.Y.2    Ye, L.L.3
  • 27
    • 79955529748 scopus 로고    scopus 로고
    • Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis
    • Hong L, Xie ZZ, Du YH, et al. Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis. Atherosclerosis 2011;216:59-66.
    • (2011) Atherosclerosis , vol.216 , pp. 59-66
    • Hong, L.1    Xie, Z.Z.2    Du, Y.H.3
  • 28
    • 34848885825 scopus 로고    scopus 로고
    • Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3
    • Miller FJ Jr, Filali M, Huss GJ, et al. Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3. Circ Res 2007;101:663-71.
    • (2007) Circ Res , vol.101 , pp. 663-671
    • Miller, F.J.1    Filali, M.2    Huss, G.J.3
  • 29
    • 34249279188 scopus 로고    scopus 로고
    • Alteration of volume-regulated chloride movement in rat cerebrovascular smooth muscle cells during hypertension
    • Shi XL, Wang GL, Zhang Z, et al. Alteration of volume-regulated chloride movement in rat cerebrovascular smooth muscle cells during hypertension. Hypertension 2007;49:1371-7.
    • (2007) Hypertension , vol.49 , pp. 1371-1377
    • Shi, X.L.1    Wang, G.L.2    Zhang, Z.3
  • 30
    • 84868198420 scopus 로고    scopus 로고
    • Decrease of intracellular chloride concentration promotes endothelial cell inflammation by activating nuclear factor-kappaB pathway
    • Yang H, Huang LY, Zeng DY, et al. Decrease of intracellular chloride concentration promotes endothelial cell inflammation by activating nuclear factor-kappaB pathway. Hypertension 2012;60:1287-93.
    • (2012) Hypertension , vol.60 , pp. 1287-1293
    • Yang, H.1    Huang, L.Y.2    Zeng, D.Y.3
  • 31
    • 33744963881 scopus 로고    scopus 로고
    • Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration
    • Moreland JG, Davis AP, Bailey G, et al. Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration. J Biol Chem 2006;281:12277-88.
    • (2006) J Biol Chem , vol.281 , pp. 12277-12288
    • Moreland, J.G.1    Davis, A.P.2    Bailey, G.3
  • 32
    • 36349022790 scopus 로고    scopus 로고
    • Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3
    • Moreland JG, Davis AP, Matsuda JJ, et al. Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3. J Biol Chem 2007;282:33958-67.
    • (2007) J Biol Chem , vol.282 , pp. 33958-33967
    • Moreland, J.G.1    Davis, A.P.2    Matsuda, J.J.3
  • 33
    • 0035827526 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase
    • 2+/calmodulin-dependent protein kinase. J Biol Chem 2001;276:20093-100.
    • (2001) J Biol Chem , vol.276 , pp. 20093-20100
    • Huang, P.1    Liu, J.2    Di, A.3
  • 35
    • 77950002937 scopus 로고    scopus 로고
    • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
    • Zaki MH, Boyd KL, Vogel P, et al. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010;32:379-91.
    • (2010) Immunity , vol.32 , pp. 379-391
    • Zaki, M.H.1    Boyd, K.L.2    Vogel, P.3
  • 36
    • 0035818549 scopus 로고    scopus 로고
    • IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation
    • Siegmund B, Lehr HA, Fantuzzi G, et al. IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci USA 2001;98:13249-54.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13249-13254
    • Siegmund, B.1    Lehr, H.A.2    Fantuzzi, G.3
  • 37
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004;118:285-96.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 38
    • 0035821249 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
    • Furuta GT, Turner JR, Taylor CT, et al. Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med 2001;193:1027-34.
    • (2001) J Exp Med , vol.193 , pp. 1027-1034
    • Furuta, G.T.1    Turner, J.R.2    Taylor, C.T.3
  • 39
    • 84861462548 scopus 로고    scopus 로고
    • Oxidative stress in inflammation-based gastrointestinal tract diseases: Challenges and opportunities
    • Kim YJ, Kim EH, Hahm KB. Oxidative stress in inflammation-based gastrointestinal tract diseases: challenges and opportunities. J Gastroenterol Hepatol 2012;27:1004-10.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 1004-1010
    • Kim, Y.J.1    Kim, E.H.2    Hahm, K.B.3
  • 40
    • 34249313567 scopus 로고    scopus 로고
    • Paneth cells, defensins, and the commensal microbiota: A hypothesis on intimate interplay at the intestinal mucosa
    • Salzman NH, Underwood MA, Bevins CL. Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa. Semin Immunol 2007;19:70-83.
    • (2007) Semin Immunol , vol.19 , pp. 70-83
    • Salzman, N.H.1    Underwood, M.A.2    Bevins, C.L.3
  • 41
    • 79955552936 scopus 로고    scopus 로고
    • Interactions between the host innate immune system and microbes in inflammatory bowel disease
    • Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology 2011;140:1729-37.
    • (2011) Gastroenterology , vol.140 , pp. 1729-1737
    • Abraham, C.1    Medzhitov, R.2
  • 42
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science 2012;336:1268-73.
    • (2012) Science , vol.336 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    Macpherson, A.J.3
  • 43
    • 6344235300 scopus 로고    scopus 로고
    • Dual roles of plasmalemmal chloride channels in induction of cell death
    • Okada Y, Maeno E, Shimizu T, et al. Dual roles of plasmalemmal chloride channels in induction of cell death. Pflugers Arch 2004;448:287-95.
    • (2004) Pflugers Arch , vol.448 , pp. 287-295
    • Okada, Y.1    Maeno, E.2    Shimizu, T.3
  • 44
    • 84859777452 scopus 로고    scopus 로고
    • The role of VDAC in cell death: Friend or foe?
    • McCommis KS, Baines CP. The role of VDAC in cell death: friend or foe? Biochim Biophys Acta 2012;1818:1444- 50.
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 1444-1450
    • McCommis, K.S.1    Baines, C.P.2
  • 45
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • Zamzami N, Kroemer G. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2001;2:67-71.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.