Oxidative stress in inflammation-based gastrointestinal tract diseases: Challenges and opportunities

Journal of Gastroenterology and Hepatology (Australia)

Volumn 27, Issue 6, 2012, Pages 1004-1010

  Kim, Yoon Jae ^a   Kim, Eun Hee ^a   Hahm, Ki Baik ^a  

^a Gachon University College of Medicine   (South Korea)

Author keywords

Antioxidant; Carcinogenesis; Inflammation; Oxidative stress; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BIOLOGICAL MARKER; CATALASE; CYCLOOXYGENASE 2; DNA; GLUTAREDOXIN; GLUTATHIONE PEROXIDASE; HEXANOYLLYSINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPROSTANE; MALONALDEHYDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN RADICAL; PANTOPRAZOLE; POLYPHENOL; PROTON PUMP INHIBITOR; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; S ADENOSYLMETHIONINE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOREDOXIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BARRETT ESOPHAGUS; CARCINOGENESIS; CELLULAR STRESS RESPONSE; COLITIS; COLORECTAL CANCER; DIGESTIVE SYSTEM CANCER; DIGESTIVE SYSTEM FUNCTION DISORDER; DIGESTIVE SYSTEM INFLAMMATION; DNA DAMAGE; DRUG INDUCED DISEASE; ENTERITIS; GASTRITIS; GASTROESOPHAGEAL REFLUX; GENE MUTATION; HELICOBACTER INFECTION; HUMAN; INTESTINE CARCINOMA; INTESTINE METAPLASIA; LIPID PEROXIDATION; LIVER CIRRHOSIS; NONHUMAN; OXIDATIVE STRESS; PANCREATITIS; PATHOGENESIS; PRECANCER; PRIORITY JOURNAL; REFLUX ESOPHAGITIS; STOMACH CANCER; ULCERATIVE COLITIS;

EID: 84861462548     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2012.07108.x     Document Type: Article

References (75)

1. Aggarwal B, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link? Biochem. Pharmacol. 2006; 72: 1605-21.
2. Kim YJ, Hong KS, Chung JW, Kim JH, Hahm KB. Prevention of colitis-associated carcinogenesis with infliximab. Cancer Prev. Res.(Phila.) 2010; 3: 1314-33.
3. Kim YJ, Lee JS, Hong KS, Chung JW, Kim JH, Hahm KB. Novel application of proton pump inhibitor for the prevention of colitis-induced colorectal carcinogenesis beyond acid suppression. Cancer Prev. Res.(Phila.) 2010; 3: 963-74.
4. Jaeschke H. Reactive oxygen and mechanisms of inflammatory liver injury: present concepts. J. Gastroenterol. Hepatol. 2011; 26 (Suppl. 1): 173-9.
5. Koike K. Hepatitis C virus contributes to hepatocarcinogenesis by modulating metabolic and intracellular signaling pathways. J. Gastroenterol. Hepatol. 2007; 22 (Suppl. 1): 108-11.
6. Klaunig JE, Kamendulis LM, Hocevar BA. Oxidative stress and oxidative damage in carcinogenesis. Toxicol. Pathol. 2011; 38: 96-109.
7. Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000; 21: 361-70.
8. Mats JM, Snchez-Jimnez FM. Role of reactive oxygen species in apoptosis: implications for cancer therapy. Int. J. Biochem. Cell Biol. 2000; 32: 157-70.
9. Kanauchi M, Nishioka H, Hashimoto T. Oxidative DNA damage and tubulointerstitial injury in diabetic nephropathy. Nephron 2002; 91: 327-9.
10. Musarrat J, Arezina Wilson J, Wani AA. Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis. Eur. J. Cancer 1996; 32A: 1209-14.
11. Wu L, Chiou CC, Chang PY, Wu JT. Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics. Clin. Chim. Acta. 2004; 339: 1-9.
12. Hahm KB, Lee KJ, Choi SY etal. Possibility of chemoprevention by the eradication of Helicobacter pylori: oxidative DNA damage and apoptosis in H.pylori infection. Am. J. Gastroenterol. 1997; 92: 1853-7.
13. Kato Y, Yoshida A, Naito M etal. Identification and quantification of N(epsilon)-(Hexanoyl)lysine in human urine by liquid chromatography/tandem mass spectrometry. Free Radic. Biol. Med. 2004; 37: 1864-74.
14. Morrow JD, Awad JA, Kato T etal. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. J. Clin. Invest. 1992; 90: 2502-7.
15. Kasai H. Chemistry-based studies on oxidative DNA damage: formation, repair, and mutagenesis. Free Radic. Biol. Med. 2002; 33: 450-6.
16. Klungland A, Rosewell I, Hollenbach S etal. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl. Acad. Sci. U. S. A. 1999; 96: 13300-5.
17. Xie Y, Yang H, Miller JH etal. Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis 2008; 29: 722-8.
18. Pathak AK, Bhutani M, Guleria R etal. Chemotherapy alone versus chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer. J. Am. Coll. Nutr. 2005; 24: 16-21.
19. Nishibayashi H, Kanayama S, Kiyohara T etal. Helicobacter pylori-induced enlarged-fold gastritis is associated with increased mutagenicity of gastric juice, increased oxidative DNA damage, and an increased risk of gastric carcinoma. J. Gastroenterol. Hepatol. 2003; 18: 1384-91.
20. Chattopadhyay MB, Cb MK, Kanna PS, Ray RS, Roy S, Chatterjee M. Combined supplementation of vanadium and beta-carotene suppresses placental glutathione S-transferase-positive foci and enhances antioxidant functions during the inhibition of diethylnitrosamine-induced rat liver carcinogenesis. J. Gastroenterol. Hepatol. 2004; 19: 683-93.
21. Phillips WA, Lord RV, Nancarrow DJ etal. Barrett's esophagus. J. Gastroenterol. Hepatol. 2011; 26: 639-48.
22. Wetscher GJ, Perdikis G, Kretchmar DH etal. Esophagitis in Sprague-Dawley rats is mediated by free radicals. Dig. Dis. Sci. 1995; 40: 1297-305.
23. Farhadi A, Fields J, Banan A, Keshavarzian A. Reactive oxygen species: are they involved in the pathogenesis of GERD, Barrett's esophagus, and the latter's progression toward esophageal cancer? Am. J. Gastroenterol. 2002; 97: 22-6.
24. Wetscher GJ, Hinder RA, Bagchi D etal. Reflux esophagitis in humans is mediated by oxygen-derived free radicals. Am. J. Surg. 1995; 170: 552-6.
25. Erbil Y, Trkoglu U, Barbaros U etal. Oxidative damage in an experimentally induced gastric and gastroduodenal reflux model. Surg. Innov. 2005; 12: 219-25.
26. Dvorak K, Payne CM, Chavarria M etal. Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus. Gut 2007; 56: 763-71.
27. Wild CP, Hardie LJ. Reflux, Barrett's oesophagus and adenocarcinoma: burning questions. Nat. Rev. Cancer 2003; 3: 676-84.
28. Chao DL, Maley C, Wu X etal. Mutagen sensitivity and neoplastic progression in patients with Barrett's esophagus: a prospective analysis. Cancer Epidemiol Biomarker Prev. 2006; 15: 1935-40.
29. Olliver JR, Hardie LJ, Gong Y etal. Risk factors, DNA damage, and disease progression in Barrett's esophagus. Cancer Epidemiol Biomarker Prev. 2005; 14: 620-5.
30. Oh TY, Lee JS, Ahn BO etal. Oxidative damages are critical in pathogenesis of reflux esophagitis: implication of antioxidants in its treatment. Free Radic. Biol. Med. 2001; 30: 905-15.
31. Martin RC, Liu Q, Wo JM, Ray MB, Li Y. Chemoprevention of carcinogenic progression to esophageal adenocarcinoma by the manganese superoxide dismutase supplementation. Clin. Cancer Res. 2007; 13: 5176-82.
32. Mork H, Scheurlen A, Al-Taie O etal. Glutathione peroxidase isoforms as part of the local antioxidative defense system in normal and Barrett's esophagus. Int. J. Cancer 2003; 105: 300-4.
33. An international association between Helicobacter pylori infection and gastric cancer. The EUROGAST Study Group. Lancet 1993; 341: 1359-62.
34. Parsonnet J, Friedman GD, Vandersteen DP etal. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 1991; 325: 1127-31.
35. Mai UE, Perez Perez GI, Allen JB, Wahl SM, Blaser MJ, Smith PD. Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa. J. Exp. Med. 1992; 175: 517-25.
36. Farinati F, Cardin R, Libera GD etal. Determinants for the development of chronic atrophic gastritis and intestinal metaplasia in the stomach. Eur. J. Cancer Prev. 1995; 4: 181-6.
37. Banerjee S, Hawksby C, Miller S, Dahill S, Beattie AD, McColl KE. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid. Gut 1994; 35: 317-22.
38. Rugge M, Cassaro M, Leandro G etal. Helicobacter pylori in promotion of gastric carcinogenesis. Dig. Dis. Sci. 1996; 41: 950-5.
39. Alam K, Arlow FL, Ma CK, Schubert TT. Decrease in ornithine decarboxylase activity after eradication of Helicobacter pylori. Am. J. Gastroenterol. 1994; 89: 888-93.
40. Davies GR, Simmonds NJ, Stevens TR etal. Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo. Gut 1994; 35: 179-85.
41. Farinati F, Cardin R, Degan P etal. Oxidative DNA damage accumulation in gastric carcinogenesis. Gut 1998; 42: 351-6.
42. Hatakeyama M. The role of Helicobacter pylori CagA in gastric carcinogenesis. Int. J. Hematol. 2006; 84: 301-8.
43. Farinati F, Cardin R, Russo VM, Busatto G, Franco M, Rugge M. Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer? Helicobacter 2003; 8: 227-34.
44. Hahm KB, Lee KJ, Kim JH, Cho SW, Chung MH. Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide. Dig. Dis. Sci. 1998; 43: 72S-7S.
45. Felley CP, Pignatelli B, Van Melle GD etal. Oxidative stress in gastric mucosa of asymptomatic humans infected with Helicobacter pylori: effect of bacterial eradication. Helicobacter 2002; 7: 342-8.
46. Ishidate T, Igarashi S, Kamatani N. Pseudodominant transmission of an autosomal recessive disease, adenine phosphoribosyltransferase deficiency. J. Pediatr. 1991; 118: 90-1.
47. Konturek PC, Kania J, Gessner U, Konturek SJ, Hahn EG, Konturek JW. Effect of vitamin C-releasing acetylsalicylic acid on gastric mucosal damage before and after Helicobacter pylori eradication therapy. Eur. J. Pharmacol. 2004; 506: 169-77.
48. Ock CY, Hong KS, Choi K etal. A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine. Biochem. Pharmacol. 2011; 81: 111-22.
49. Damiani CR, Benetton CA, Stoffel C etal. Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium. J. Gastroenterol. Hepatol. 2007; 22: 1846-51.
50. Seril DN, Liao J, Yang G, Yang CS. Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models. Carcinogenesis 2003; 24: 353-62.
51. D'Inca R, Cardin R, Benazzato L, Angriman I, Martines D, Sturniolo GC. Oxidative DNA damage in the mucosa of ulcerative colitis increases with disease duration and dysplasia. Inflamm. Bowel Dis. 2004; 10: 23-7.
52. Liao J, Seril DN, Lu G etal. Increased susceptibility of chronic ulcerative colitis-induced carcinoma development in DNA repair enzyme Ogg1 deficient mice. Mol. Carcinog. 2008; 47: 638-46.
53. Boughton-Smith NK, Evans SM, Hawkey CJ etal. Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet 1993; 342: 338-40.
54. Nair J, Gansauge F, Beger H, Dolara P, Winde G, Bartsch H. Increased etheno-DNA adducts in affected tissues of patients suffering from Crohn's disease, ulcerative colitis, and chronic pancreatitis. Antioxid. Redox Signal. 2006; 8: 1003-10.
55. Keshavarzian A, Banan A, Farhadi A etal. Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease. Gut 2003; 52: 720-8.
56. Hussain SP, Amstad P, Raja K etal. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res. 2000; 60: 3333-7.
57. Tarmin L, Yin J, Harpaz N etal. Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms. Cancer Res. 1995; 55: 2035-8.
58. Gasche C, Chang CL, Rhees J, Goel A, Boland CR. Oxidative stress increases frameshift mutations in human colorectal cancer cells. Cancer Res. 2001; 61: 7444-8.
59. Tanaka K, Namba T, Arai Y etal. Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis. J. Biol. Chem. 2007; 282: 23240-52.
60. Oz HS, Chen TS, McClain CJ, de Villiers WJ. Antioxidants as novel therapy in a murine model of colitis. J. Nutr. Biochem. 2005; 16: 297-304.
61. Najafzadeh M, Reynolds PD, Baumgartner A, Jerwood D, Anderson D. Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease. Biofactors 2007; 31: 191-200.
62. You Y, Fu J, Meng J, Huang G, Liu Y. Effect of N-acetylcysteine on the murine model of colitis induced by dextran sodium sulfate through up-regulating PON1 activity. Dig. Dis. Sci. 2009; 54: 1643-50.
63. Kolgazi M, Jahovic N, Yuksel M, Ercan F, Alican I. Alpha-lipoic acid modulates gut inflammation induced by trinitrobenzene sulfonic acid in rats. J. Gastroenterol. Hepatol. 2007; 22: 1859-65.
64. Ock CY, Kim E, Hong H etal. Prevention of colitis-associated colorectal cancer with 8-hydroxydeoxyguanosine. Cancer Prev. Res.(Phila.) 2011; 4: 1507-21.
65. Adebayo D, Bjarnason I. Is non-steroidal anti-inflammaory drug (NSAID) enteropathy clinically more important than NSAID gastropathy? Postgrad. Med. J. 2006; 82: 186-91.
66. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat. New Biol. 1971; 231: 232-5.
67. Chattopadhyay I, Bandyopadhyay U, Biswas K, Maity P, Banerjee RK. Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen. Free Radic. Biol. Med. 2006; 40: 1397-408.
68. Omatsu T, Naito Y, Handa O etal. Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury. J. Gastroenterol. 2010; 45: 692-702.
69. Lim YJ, Lee JS, Ku YS, Hahm KB. Rescue strategies against non-steroidal anti-inflammatory drug-induced gastroduodenal damage. J. Gastroenterol. Hepatol. 2009; 24: 1169-78.
70. Rehn M, Olsson A, Reckzeh K etal. Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche. Blood 2011; 118: 1534-43.
71. Wilson WR, Hay MP. Targeting hypoxia in cancer therapy. Nat. Rev. Cancer 2011; 11: 393-410.
72. Welford SM, Giaccia AJ. Hypoxia and senescence: the impact of oxygenation on tumor suppression. Mol. Cancer Res. 2011; 9: 538-44.
73. Grek CL, Tew KD. Redox metabolism and malignancy. Curr. Opin. Pharmacol. 2010; 10: 362-8.
74. Valko M, Rhodes CJ, Moncol J, Izakovic M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006; 160: 1-40.
75. Kundu JK, Surh YJ. Inflammation: gearing the journey to cancer. Mutat. Res. 2008; 659: 15-30.