Novel peptide with a specific calcium-binding capacity from whey protein hydrolysate and the possible chelating mode

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 42, 2014, Pages 10274-10282

  Zhao, Lina ^a   Huang, Qimin ^a   Huang, Shunli ^a   Lin, Jiaping ^a   Wang, Shaoyun ^a   Huang, Yifan ^a   Hong, Jing ^a   Rao, Pingfan ^a  

^a FUZHOU UNIVERSITY   (China)

Author keywords

Calcium binding peptide; Characterization; Chelating mode; Purification; Whey protein

Indexed keywords

PURIFICATION;

CALCIUM BINDING; NOVEL PEPTIDES; WHEY PROTEIN HYDROLYSATES; WHEY PROTEINS;

CHARACTERIZATION;

CALCIUM; CALCIUM INTAKE; MILK PROTEIN; PEPTIDE; PROTEIN HYDROLYSATE; WHEY PROTEIN;

ANALYSIS; CALCIUM INTAKE; CHEMICAL MODEL; CHEMISTRY; HUMAN; METABOLISM;

CALCIUM; CALCIUM, DIETARY; HUMANS; MILK PROTEINS; MODELS, CHEMICAL; PEPTIDES; PROTEIN HYDROLYSATES;

EID: 84908426237     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf502412f     Document Type: Article

References (36)

1. O'Keeffe, M. B.; FitzGerald, R. J. Antioxidant effects of enzymatic hydrolysates of whey protein concentrate on cultured human endothelial cells. Int. Dairy J. 2014, 36, 128-135.
2. O'Loughlin, I. B.; Murray, B. A.; Brodkorb, A.; FitzGerald, R. J.; Kelly, P. M. Production of whey protein isolate hydrolysate fractions with enriched ACE-inhibitory activity. Int. Dairy J. 2014, 38, 101-103.
3. Zhao, L. N.; Huang, S. L.; Cai, X. X.; Hong, J.; Wang, S. Y. A specific peptide with calcium chelating capacity isolated from whey protein hydrolysate. J. Funct. Foods 2014, 10, 46-53.
4. Xu, R. Calcium binding of peptides derived from enzymatic hydrolysates of whey protein concentrate. Int. J. Dairy Technol. 2009, 62, 170-173.
5. Bennett, T.; Desmond, A.; Harrington, M.; McDonagh, D.; FitzGerald, R.; Flynn, A.; Cashman, K. D. The effect of high intakes of casein and casein phosphopeptide on calcium absorption in the rat. Br. J. Nutr. 2000, 83, 673-680.
6. Kim, S.; Shin, H.; Lim, J. Separation of calcium-binding protein derived from enzymatic hydrolysates of cheese whey protein. Asian-Australas. J. Anim. Sci. 2004, 17, 712-718.
7. Singh, G.; Muthukumarappan, K. Influence of calcium fortification on sensory, physical and rheological characteristics of fruit yogurt. LWT - Food Sci. Technol. 2008, 41, 1145-1152.
8. Guéguen, L.; Pointillart, A. The bioavailability of dietary calcium. J. Am. Coll. Nutr. 2000, 19, 119S-136S.
9. Cilla, A.; Lagarda, M. J.; Alegría, A.; de Ancos, B.; Cano, M. P.; Sánchez-Moreno, C.; Plaza, L.; Barberá, R. Effect of processing and food matrix on calcium and phosphorous bioavailability from milkbased fruit beverages in Caco-2 cells. Food Res. Int. 2011, 44, 3030-3038.
10. Kim, S.; Lim, J. Calcium-binding peptides derived from tryptic hydrolysates of cheese whey protein. Asian-Australas. J. Anim. Sci. 2004, 17, 1459-1464.
11. Lee, S. H.; Song, K. B. Isolation of a calcium-binding peptide from enzymatic hydrolysates of porcine blood plasma protein. J. Korean Soc. Appl. Biol. Chem. 2009, 52, 290-294.
12. Bronner, F.; Pansu, D. Nutritional aspects of calcium absorption. J. Nutr. 1999, 129, 9-12.
13. Rerat, A.; Nunes, C. S.; Mendy, F.; Roger, L. Amino acid absorption and production of pancreatic hormones in nonanaesthetized pigs after duodenal infusions of a milk enzymic hydrolysate or free amino acids. Br. J. Nutr. 1988, 60, 121-136.
14. Chaud, M. V.; Izumi, C.; Nahaal, Z.; Shuhama, T.; Bianchi, M. D. L. P.; Freitas, O. D. Iron derivatives from casein hydrolysates as a potential source in the treatment of iron deficiency. J. Agric. Food Chem. 2002, 50, 871-877.
15. Kim, S.; Seo, I.; Khan, M.; Ki, K.; Lee, W.; Lee, H.; Shin, H.; Kim, H. Enzymatic hydrolysis of heated whey: Iron-binding ability of peptides and antigenic protein fractions. J. Dairy Sci. 2007, 90, 4033-4042.
16. Sato, R.; Shindo, M.; Gunshin, H.; Noguchi, T.; Naito, H. Characterization of phosphopeptide derived from bovine β-casein: An inhibitor to intraintestinal precipitation of calcium phosphate. Biochim. Biophys. Acta 1991, 1077, 413-415.
17. Gitelman, H. J. An improved automated procedure for the determination of calcium in biological specimens. Anal. Biochem. 1967, 18, 521-531.
18. Chen, D.; Liu, Z.; Huang, W.; Zhao, Y.; Dong, S.; Zeng, M. Purification and characterisation of a zinc-binding peptide from oyster protein hydrolysate. J. Funct. Foods 2013, 5, 689-697.
19. Zhou, J.; Wang, X.; Ai, T.; Cheng, X.; Guo, H.; Teng, G.; Mao, X. Preparation and characterization of β-lactoglobulin hydrolysate-iron complexes. J. Dairy Sci. 2012, 95, 4230-4236.
20. Megías, C.; Pedroche, J.; Yust, M. M.; Girón-Calle, J.; Alaiz, M.; Millán, F.; Vioque, J. Affinity purification of copper-chelating peptides from sunflower protein hydrolysates. J. Agric. Food Chem. 2007, 55, 6509-6514.
21. Huang, G. R.; Ren, Z. Y.; Jiang, J. X.; Chen, W. W. Purification of a hepta-peptide with iron binding activity from shrimp processing by-products hydrolysates. Adv. J. Food Sci. Technol. 2012, 4, 207-212.
22. Huang, G.; Ren, L.; Jiang, J. Purification of a histidinecontaining peptide with calcium binding activity from shrimp processing byproducts hydrolysate. Eur. Food Res. Technol. 2011, 232, 281-287.
23. Huang, G.; Ren, Z.; Jiang, J. Separation of iron-binding peptides from shrimp processing by-products hydrolysates. Food Bioprocess Technol. 2011, 4, 1527-1532.
24. 3+-L-amino acid complexes at pH 6.60. J. Agric. Food Chem. 1995, 43, 1436-1443.
25. 3+. J. Agric. Food Chem. 2009, 57, 4593-4597.
26. Miquel, E.; Farré, R. Effects and future trends of casein phosphopeptides on zinc bioavailability. Trends Food Sci. Technol. 2007, 18, 139-143.
27. Jung, W. K.; Karawita, R.; Heo, S. J.; Lee, B. J.; Kim, S. K.; Jeon, Y. J. Recovery of a novel Ca-binding peptide from Alaska Pollack (Theragra chalcogramma) backbone by pepsinolytic hydrolysis. Process Biochem. 2006, 41, 2097-2100.
28. Jung, W. K.; Park, P. J.; Byun, H. G.; Moon, S. H.; Kim, S. K. Preparation of hoki (Johnius belengerii ) bone oligophosphopeptide with a high affinity to calcium by carnivorous intestine crude proteinase. Food Chem. 2005, 91, 333-340.
29. Wu, H. H.; Liu, Z. Y.; Zhao, Y. H.; Zeng, M. Y. Enzymatic preparation and characterization of iron-chelating peptides from anchovy (Engraulis japonicus) muscle protein. Food Res. Int. 2012, 48, 435-441.
30. 2+ complex of an ethidium-peptide conjugate. Inorg. Chem. 1999, 38, 1368-1370.
31. Armas, A.; Sonois, V.; Mothes, E.; Mazarguil, H.; Faller, P. Zinc(II) binds to the neuroprotective peptide humanin. J. Inorg. Biochem. 2006, 100, 1672-1678.
32. Blindauer, C. A.; Harvey, I.; Bunyan, K. E.; Stewart, A. J.; Sleep, D.; Harrison, D. J.; Berezenko, S.; Sadler, P. J. Structure, properties, and engineering of the major zinc binding site on human albumin. J. Biol. Chem. 2009, 284, 23116-23124.
33. Reddi, A. R.; Guzman, T. R.; Breece, R. M.; Tierney, D. L.; Gibney, B. R. Deducing the energetic cost of protein folding in zinc finger proteins using designed metallopeptides. J. Am. Chem. Soc. 2007, 129, 12815-12827.
34. Beyer, R. L.; Hoang, H. N.; Appleton, T. G.; Fairlie, D. P. Metal clips induce folding of a short unstructured peptide into an α-helix via turn conformations in water. Kinetic versus thermodynamic products. J. Am. Chem. Soc. 2004, 126, 15096-15105.
35. Bao, X. L.; Lv, Y.; Yang, B. C.; Ren, C. G.; Guo, S. T. A study of the soluble complexes formed during calcium binding by soybean protein hydrolysates. J. Food Sci. 2008, 73, C117-C121.
36. Wang, X.; Zhou, J.; Tong, P.; Mao, X. Zinc-binding capacity of yak casein hydrolysate and the zinc-releasing characteristics of casein hydrolysate-zinc complexes. J. Dairy Sci. 2011, 94, 2731-2740.