Ligustilide inhibits microglia-mediated proinflammatory cytokines production and inflammatory pain

Brain Research Bulletin

Volumn 109, Issue , 2014, Pages 54-60

  Zhu, Ming Di ^a   Zhao, Lin Xia ^a   Wang, Xiao Tian ^a   Gao, Yong Jing ^a   Zhang, Zhi Jun ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Complete freund's adjuvant; Inflammatory pain; Ligustilide; Lipopolysaccharide; Microglia; Proinflammatory cytokines

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGUSTILIDE; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; ANTIINFLAMMATORY AGENT; CALCIUM BINDING PROTEIN; CYTOKINE; FREUND ADJUVANT; GAMMA BUTYROLACTONE;

ADULT; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; HYPERALGESIA; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY PAIN; MALE; MICROGLIA; MICROGLIAL CELL CULTURE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; INFLAMMATION; METABOLISM; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PATHOLOGY; SPINAL CORD; TIME; TRANSFORMED CELL LINE;

4-BUTYROLACTONE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CALCIUM-BINDING PROTEINS; CELL LINE, TRANSFORMED; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FREUND'S ADJUVANT; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MICE; MICROFILAMENT PROTEINS; MICROGLIA; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RNA, MESSENGER; SPINAL CORD; TIME FACTORS;

EID: 84908375175     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2014.10.002     Document Type: Article

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