Z-ligustilide activates the Nrf2/HO-1 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro

Brain Research

Volumn 1520, Issue , 2013, Pages 168-177

  Peng, Bin ^a   Zhao, Peng ^a,b   Lu, Ya Peng ^a   Chen, Miao Miao ^a   Sun, Hua ^a   Wu, Xiao Mei ^a   Zhu, Li ^a  

^a NANTONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Heme oxygenase 1; Ischemia; NF E2 related factor 2; Rat; Z ligustilide

Indexed keywords

HEME OXYGENASE 1; LIGUSTILIDE; NORPHENAZONE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; Z LIGUSTILIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NISSL STAINING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIMARY SOMATOSENSORY CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; RNA EXTRACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; THERAPY EFFECT; UPREGULATION; WESTERN BLOTTING;

4-BUTYROLACTONE; ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; CELL LINE; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; HEME OXYGENASE-1; HUMANS; MALE; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANGELICA SINENSIS; RATTUS; RODENTIA;

EID: 84879176501     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.05.009     Document Type: Article

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