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Volumn 121, Issue 2, 2013, Pages 89-94

Microglial regulation of neuropathic pain

Author keywords

Microglia; Neuropathic pain; Purinergic signaling; Spinal cord; Transcription factor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CCR2; FIBRONECTIN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE LYN; PURINERGIC P2X RECEPTOR AGONIST; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X4 RECEPTOR AGONIST; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2X7 RECEPTOR AGONIST; PURINERGIC P2Y12 RECEPTOR; SECONDARY LYMPHOID TISSUE CHEMOKINE; UNCLASSIFIED DRUG;

EID: 84874130784     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.12R14CP     Document Type: Review
Times cited : (103)

References (50)
  • 1
    • 0033526651 scopus 로고    scopus 로고
    • Neuropathic pain: Aetiology, symptoms, mechanisms, and management
    • Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet. 1999;353:1959-1964.
    • (1999) Lancet. , vol.353 , pp. 1959-1964
    • Woolf, C.J.1    Mannion, R.J.2
  • 2
    • 0036829011 scopus 로고    scopus 로고
    • Can we conquer pain?
    • DOI 10.1038/nn942
    • Scholz J, Woolf CJ. Can we conquer pain? Nat Neurosci. 2002;5:1062-1067. (Pubitemid 35247200)
    • (2002) Nature Neuroscience , vol.5 , Issue.SUPPL. , pp. 1062-1067
    • Scholz, J.1    Woolf, C.J.2
  • 3
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science. 2000;288:1765-1769.
    • (2000) Science. , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 4
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: A maladap-tive response of the nervous system to damage
    • Costigan M, Scholz J, Woolf CJ. Neuropathic pain: a maladap-tive response of the nervous system to damage. Annu Rev Neurosci. 2009;32:1-32.
    • (2009) Annu Rev Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 5
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330:841-845.
    • (2010) Science. , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 7
    • 19744380563 scopus 로고    scopus 로고
    • Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • DOI 10.1126/science.1110647
    • Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science. 2005;308:1314-1318. (Pubitemid 40746128)
    • (2005) Science , vol.308 , Issue.5726 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 8
    • 36048991728 scopus 로고    scopus 로고
    • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain
    • DOI 10.1523/JNEUROSCI.3016-07.2007
    • Zhang J, Shi XQ, Echeverry S, Mogil JS, De Koninck Y, Rivest S. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J Neurosci. 2007;27:12396-12406. (Pubitemid 350085465)
    • (2007) Journal of Neuroscience , vol.27 , Issue.45 , pp. 12396-12406
    • Zhang, J.1    Xiang, Q.S.2    Echeverry, S.3    Mogil, J.S.4    De Koninck, Y.5    Rivest, S.6
  • 9
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • DOI 10.1038/nn2014, PII NN2014
    • Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007;10:1538-1543. (Pubitemid 350175883)
    • (2007) Nature Neuroscience , vol.10 , Issue.12 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.V.5
  • 10
    • 33746701380 scopus 로고    scopus 로고
    • P2X receptors as cell-surface ATP sensors in health and disease
    • DOI 10.1038/nature04886, PII NATURE04886
    • Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature. 2006;442:527-532. (Pubitemid 44167906)
    • (2006) Nature , vol.442 , Issue.7102 , pp. 527-532
    • Khakh, B.S.1    Alan North, R.2
  • 12
    • 46449134214 scopus 로고    scopus 로고
    • Purinergic signalling and disorders of the central nervous system
    • DOI 10.1038/nrd2605, PII NRD2605
    • Burnstock G. Purinergic signalling and disorders of the central nervous system. Nat Rev Drug Discov. 2008;7:575-590. (Pubitemid 351927723)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.7 , pp. 575-590
    • Burnstock, G.1
  • 13
    • 0042968804 scopus 로고    scopus 로고
    • 4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
    • DOI 10.1038/nature01786
    • Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, et al. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature. 2003; 424:778-783. (Pubitemid 37021707)
    • (2003) Nature , vol.424 , Issue.6950 , pp. 778-783
    • Tsuda, M.1    Shigemoto-Mogami, Y.2    Koizumi, S.3    Mizokoshi, A.4    Kohsaka, S.5    Salter, M.W.6    Inoue, K.7
  • 14
    • 56149096976 scopus 로고    scopus 로고
    • Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain
    • Ulmann L, Hatcher JP, Hughes JP, Chaumont S, Green PJ, Conquet F, et al. Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain. J Neurosci. 2008;28:11263-11268.
    • (2008) J Neurosci. , vol.28 , pp. 11263-11268
    • Ulmann, L.1    Hatcher, J.P.2    Hughes, J.P.3    Chaumont, S.4    Green, P.J.5    Conquet, F.6
  • 15
    • 67650222417 scopus 로고    scopus 로고
    • Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
    • Tsuda M, Kuboyama K, Inoue T, Nagata K, Tozaki-Saitoh H, Inoue K. Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays. Mol Pain. 2009;5:28.
    • (2009) Mol Pain. , vol.5 , pp. 28
    • Tsuda, M.1    Kuboyama, K.2    Inoue, T.3    Nagata, K.4    Tozaki-Saitoh, H.5    Inoue, K.6
  • 16
    • 13144276331 scopus 로고    scopus 로고
    • Neuropathic pain and spinal microglia: A big problem from molecules in 'small' glia
    • DOI 10.1016/j.tins.2004.12.002, PII S0166223604003698
    • Tsuda M, Inoue K, Salter MW. Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci. 2005;28:101-107. (Pubitemid 40178927)
    • (2005) Trends in Neurosciences , vol.28 , Issue.2 , pp. 101-107
    • Tsuda, M.1    Inoue, K.2    Salter, M.W.3
  • 17
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • Trang T, Beggs S, Wan X, Salter MW. P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation. J Neurosci. 2009;29:3518-3528.
    • (2009) J Neurosci. , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 18
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • Beggs S, Trang T, Salter MW. P2X4R+ microglia drive neuropathic pain. Nat Neurosci. 2012;15:1068-1073.
    • (2012) Nat Neurosci. , vol.15 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 20
    • 33646259685 scopus 로고    scopus 로고
    • Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X(4), a key molecule for mechanical allodynia
    • Nasu-Tada K, Koizumi S, Tsuda M, Kunifusa E, Inoue K. Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X(4), a key molecule for mechanical allodynia. Glia. 2006;53:769-775.
    • (2006) Glia. , vol.53 , pp. 769-775
    • Nasu-Tada, K.1    Koizumi, S.2    Tsuda, M.3    Kunifusa, E.4    Inoue, K.5
  • 21
    • 79960941570 scopus 로고    scopus 로고
    • Peripheral nerve injury alters blood-spinal cord barrier functional and molecular integrity through a selective inflammatory pathway
    • Echeverry S, Shi XQ, Rivest S, Zhang J. Peripheral nerve injury alters blood-spinal cord barrier functional and molecular integrity through a selective inflammatory pathway. J Neurosci. 2011;31: 10819-10828.
    • (2011) J Neurosci. , vol.31 , pp. 10819-10828
    • Echeverry, S.1    Shi, X.Q.2    Rivest, S.3    Zhang, J.4
  • 22
    • 36448966388 scopus 로고    scopus 로고
    • 4 receptor upregulation and neuropathic pain after peripheral nerve injury
    • DOI 10.1002/glia.20591
    • Tsuda M, Tozaki-Saitoh H, Masuda T, Toyomitsu E, Tezuka T, Yamamoto T, et al. Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury. Glia. 2008;56:50-58. (Pubitemid 350172730)
    • (2008) GLIA , vol.56 , Issue.1 , pp. 50-58
    • Tsuda, M.1    Tozaki-Saitoh, H.2    Masuda, T.3    Toyomitsu, E.4    Tezuka, T.5    Yamamoto, T.6    Inoue, K.7
  • 23
    • 77449099299 scopus 로고    scopus 로고
    • Mechanisms underlying fibronectin-induced upregulation of P2XR expression in microglia: Distinct roles of PI3K-Akt and MEK-ERK signaling pathways
    • Tsuda M, Toyomitsu E, Kometani M, Tozaki-Saitoh H, Inoue K. Mechanisms underlying fibronectin-induced upregulation of P2XR expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signaling pathways. J Cell Mol Med. 2009;13: 3251-3259.
    • (2009) J Cell Mol Med. , vol.13 , pp. 3251-3259
    • Tsuda, M.1    Toyomitsu, E.2    Kometani, M.3    Tozaki-Saitoh, H.4    Inoue, K.5
  • 24
    • 3042656885 scopus 로고    scopus 로고
    • 4 receptor in rat C6 glioma by tumor-associated macrophages and activated microglia
    • DOI 10.1016/j.jneuroim.2004.04.005, PII S0165572804001171
    • Guo LH, Trautmann K, Schluesener HJ. Expression of P2X4 receptor in rat C6 glioma by tumor-associated macrophages and activated microglia. J Neuroimmunol. 2004;152:67-72. (Pubitemid 38829703)
    • (2004) Journal of Neuroimmunology , vol.152 , Issue.1-2 , pp. 67-72
    • Guo, L.-H.1    Trautmann, K.2    Schluesener, H.J.3
  • 25
    • 18844415609 scopus 로고    scopus 로고
    • 4 receptor expression
    • DOI 10.1016/j.jneuroim.2005.02.016, PII S0165572805000846
    • Schwab JM, Guo L, Schluesener HJ. Spinal cord injury induces early and persistent lesional P2X4 receptor expression. J Neuro-immunol. 2005;163:185-189. (Pubitemid 40692962)
    • (2005) Journal of Neuroimmunology , vol.163 , Issue.1-2 , pp. 185-189
    • Schwab, J.M.1    Guo, L.2    Schluesener, H.J.3
  • 26
    • 79955623602 scopus 로고    scopus 로고
    • Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development
    • Biber K, Tsuda M, Tozaki-Saitoh H, Tsukamoto K, Toyomitsu E, Masuda T, et al. Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development. EMBO J. 2011;30:1864-1873.
    • (2011) EMBO J. , vol.30 , pp. 1864-1873
    • Biber, K.1    Tsuda, M.2    Tozaki-Saitoh, H.3    Tsukamoto, K.4    Toyomitsu, E.5    Masuda, T.6
  • 27
    • 36549041874 scopus 로고    scopus 로고
    • 4 receptors by lysosomal targeting, glycan protection and exocytosis
    • DOI 10.1242/jcs.010348
    • Qureshi OS, Paramasivam A, Yu JC, Murrell-Lagnado RD. Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis. J Cell Sci. 2007;120:3838-3849. (Pubitemid 350187365)
    • (2007) Journal of Cell Science , vol.120 , Issue.21 , pp. 3838-3849
    • Qureshi, O.S.1    Paramasivam, A.2    Yu, J.C.H.3    Murrell-Lagnado, R.D.4
  • 28
    • 67649395964 scopus 로고    scopus 로고
    • Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells
    • Boumechache M, Masin M, Edwardson JM, Gorecki DC, Murrell-Lagnado R. Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells. J Biol Chem. 2009;284:13446-13454.
    • (2009) J Biol Chem. , vol.284 , pp. 13446-13454
    • Boumechache, M.1    Masin, M.2    Edwardson, J.M.3    Gorecki, D.C.4    Murrell-Lagnado, R.5
  • 31
    • 0031054641 scopus 로고    scopus 로고
    • Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin
    • DOI 10.1084/jem.185.3.579
    • Ferrari D, Chiozzi P, Falzoni S, Hanau S, Di Virgilio F. Puriner-gic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J Exp Med. 1997;185: 579-582. (Pubitemid 27078376)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.3 , pp. 579-582
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Hanau, S.4    Di Virgilio, F.5
  • 32
    • 0033836116 scopus 로고    scopus 로고
    • Extracellular ATP triggers tumor necrosis factor-α release from rat microglia
    • DOI 10.1046/j.1471-4159.2000.0750965.x
    • Hide I, Tanaka M, Inoue A, Nakajima K, Kohsaka S, Inoue K, et al. Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem. 2000;75:965-972. (Pubitemid 30660484)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.3 , pp. 965-972
    • Hide, I.1    Tanaka, M.2    Inoue, A.3    Nakajima, K.4    Kohsaka, S.5    Inoue, K.6    Nakata, Y.7
  • 33
    • 0034814542 scopus 로고    scopus 로고
    • Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5
    • DOI 10.1046/j.1471-4159.2001.00514.x
    • Shigemoto-Mogami Y, Koizumi S, Tsuda M, Ohsawa K, Kohsaka S, Inoue K. Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5. J Neurochem. 2001;78:1339-1349. (Pubitemid 32899765)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.6 , pp. 1339-1349
    • Shigemoto-Mogami, Y.1    Koizumi, S.2    Tsuda, M.3    Ohsawa, K.4    Kohsaka, S.5    Inoue, K.6
  • 36
    • 80053341816 scopus 로고    scopus 로고
    • Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model
    • He WJ, Cui J, Du L, Zhao YD, Burnstock G, Zhou HD, et al. Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model. Behav Brain Res. 2012;226:163-170.
    • (2012) Behav Brain Res. , vol.226 , pp. 163-170
    • He, W.J.1    Cui, J.2    Du, L.3    Zhao, Y.D.4    Burnstock, G.5    Zhou, H.D.6
  • 37
    • 33751165071 scopus 로고    scopus 로고
    • A-740003 [N-(1-{[(cyanoimino)(5-quinolinyl-amino) methyl]amino}-2, 2-dimethylpropyl)-2-(3, 4-dimethoxy-phenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat
    • Honore P, Donnelly-Roberts D, Namovic MT, Hsieh G, Zhu CZ, Mikusa JP, et al. A-740003 [N-(1-{[(cyanoimino)(5-quinolinyl-amino) methyl]amino}-2, 2-dimethylpropyl)-2-(3, 4-dimethoxy-phenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat. J Pharmacol Exp Ther. 2006;319:1376-1385.
    • (2006) J Pharmacol Exp Ther. , vol.319 , pp. 1376-1385
    • Honore, P.1    Donnelly-Roberts, D.2    Namovic, M.T.3    Hsieh, G.4    Zhu, C.Z.5    Mikusa, J.P.6
  • 39
    • 57249111810 scopus 로고    scopus 로고
    • Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
    • Kataoka A, Tozaki-Saitoh H, Koga Y, Tsuda M, Inoue K. Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J Neurochem. 2009;108:115-125.
    • (2009) J Neurochem. , vol.108 , pp. 115-125
    • Kataoka, A.1    Tozaki-Saitoh, H.2    Koga, Y.3    Tsuda, M.4    Inoue, K.5
  • 40
    • 77954325416 scopus 로고    scopus 로고
    • P2X7 receptor activation induces CXCL2 production in micro-glia through NFAT and PKC/MAPK pathways
    • Shiratori M, Tozaki-Saitoh H, Yoshitake M, Tsuda M, Inoue K. P2X7 receptor activation induces CXCL2 production in micro-glia through NFAT and PKC/MAPK pathways. J Neurochem. 2010;114:810-819.
    • (2010) J Neurochem. , vol.114 , pp. 810-819
    • Shiratori, M.1    Tozaki-Saitoh, H.2    Yoshitake, M.3    Tsuda, M.4    Inoue, K.5
  • 41
    • 77951764686 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation
    • Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S. Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation. Pain. 2010;149:305-315.
    • (2010) Pain. , vol.149 , pp. 305-315
    • Kiguchi, N.1    Maeda, T.2    Kobayashi, Y.3    Fukazawa, Y.4    Kishioka, S.5
  • 42
    • 44949147139 scopus 로고    scopus 로고
    • P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury
    • Tozaki-Saitoh H, Tsuda M, Miyata H, Ueda K, Kohsaka S, Inoue K. P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury. J Neurosci. 2008;28: 4949-4956.
    • (2008) J Neurosci. , vol.28 , pp. 4949-4956
    • Tozaki-Saitoh, H.1    Tsuda, M.2    Miyata, H.3    Ueda, K.4    Kohsaka, S.5    Inoue, K.6
  • 43
    • 40849089273 scopus 로고    scopus 로고
    • 12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain
    • DOI 10.1523/JNEUROSCI.5589-07.2008
    • Kobayashi K, Yamanaka H, Fukuoka T, Dai Y, Obata K, Noguchi K. P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain. J Neurosci. 2008;28:2892-2902. (Pubitemid 351398864)
    • (2008) Journal of Neuroscience , vol.28 , Issue.11 , pp. 2892-2902
    • Kobayashi, K.1    Yamanaka, H.2    Fukuoka, T.3    Dai, Y.4    Obata, K.5    Noguchi, K.6
  • 45
    • 33947540584 scopus 로고    scopus 로고
    • 12 receptors in ATP-induced microglial chemotaxis
    • DOI 10.1002/glia.20489
    • Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S. Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis. Glia. 2007;55:604-616. (Pubitemid 46474302)
    • (2007) GLIA , vol.55 , Issue.6 , pp. 604-616
    • Ohsawa, K.1    Irino, Y.2    Nakamura, Y.3    Akazawa, C.4    Inoue, K.5    Kohsaka, S.6
  • 47
    • 78649362101 scopus 로고    scopus 로고
    • Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn
    • Maeda M, Tsuda M, Tozaki-Saitoh H, Inoue K, Kiyama H. Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn. Glia. 2010;58: 1838-1846.
    • (2010) Glia. , vol.58 , pp. 1838-1846
    • Maeda, M.1    Tsuda, M.2    Tozaki-Saitoh, H.3    Inoue, K.4    Kiyama, H.5
  • 48
    • 84861123981 scopus 로고    scopus 로고
    • IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
    • Masuda T, Tsuda M, Yoshinaga R, Tozaki-Saitoh H, Ozato K, Tamura T, et al. IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype. Cell Rep. 2012;1: 334-340.
    • (2012) Cell Rep. , vol.1 , pp. 334-340
    • Masuda, T.1    Tsuda, M.2    Yoshinaga, R.3    Tozaki-Saitoh, H.4    Ozato, K.5    Tamura, T.6
  • 49
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • DOI 10.1146/annurev.immunol.26.021607.090400
    • Tamura T, Yanai H, Savitsky D, Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol. 2008;26:535-584. (Pubitemid 351600385)
    • (2008) Annual Review of Immunology , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 50
    • 0028178223 scopus 로고
    • Regulation of IFN-gamma-induced nuclear expression of IFN consensus sequence binding protein in murine peritoneal macrophages
    • Politis AD, Ozato K, Coligan JE, Vogel SN. Regulation of IFN-gamma-induced nuclear expression of IFN consensus sequence binding protein in murine peritoneal macrophages. J Immunol. 1994;152:2270-2278.
    • (1994) J Immunol. , vol.152 , pp. 2270-2278
    • Politis, A.D.1    Ozato, K.2    Coligan, J.E.3    Vogel, S.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.