Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia

Neuropharmacology

Volumn 60, Issue 6, 2011, Pages 823-831

  Or, Terry C T ^a,b   Yang, Cindy L H ^a   Law, Anna H Y ^a,b   Li, James C B ^a,b   Lau, Allan S Y ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

BV 2; Human peripheral blood monocyte derived macrophages (PBMac); Ligusticum chuanxiong (LCX); Lipopolysaccharide (LPS); Microglia; Mitogen activated protein kinases (MAPK); mRNA stability; Nitric oxide; Nuclear factor kappa B (NF B); Senkyunolide A; Tumor necrosis factor alpha (TNF ); Z Ligustilide

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGUSTICUM CHUANXIONG EXTRACT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SENKYUNOLIDE A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; Z LIGUSTILIDE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY TEST; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING;

4-BUTYROLACTONE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOFURANS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79952447872     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.12.002     Document Type: Article

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