Efficient cardiomyogenic differentiation of bone marrow mesenchymal stromal cells by combination of Wnt11 and bone morphogenetic protein 2

Experimental Biology and Medicine

Volumn 237, Issue 7, 2012, Pages 768-776

  Zhang, Zhifeng ^a   Li, Huixian ^a   Ma, Zhifeng ^a   Feng, Junqing ^a   Gao, Pan ^a   Dong, Hongyan ^a   Zhang, Zhongming ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

BM MSCs; BMP 2; Cardiomyocyte; Differentiation; Wnt11

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CD11B ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; HERMES ANTIGEN; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; THY 1 ANTIGEN; TRANSCRIPTION FACTOR NKX2.5; TROPONIN I; WNT11 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; COCULTURE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STROMA CELL; MICROENVIRONMENT; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMAL CELLS; MICE; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WNT PROTEINS;

EID: 84865336270     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2012.011291     Document Type: Article

References (27)

1. Flaherty MP, Abdel-Latif A, Li Q, Hunt G, Ranjan S, Ou Q, Tang XL, Johnson RK, Bolli R, Dawn B. Noncanonical Wnt11 signaling was sufficient to induce cardiomyogenic differentiation in unfractionated bone marrow mononuclear cells. Circulation 2008;117:2241-52
2. Povelones M, Nusse R. Wnt signaling sees spots. Nat Cell Biol 2002;4:E249-250
3. Nakamura T, Sano M, Songyang Z, Schneider MD. A Wnt and bcatenin-dependent pathway for mammalian cardiac myogenesis. Proc Natl Acad Sci USA 2003;100:5834-9
4. Belema Bedada F, Technau A, Ebelt H, Schulze M, Braun T. Activation of myogenic differentiation pathways in adult bone marrow-derived stem cells. Mol Cell Biol 2005;25:9509-19
5. Zhang H, Bradley A. Mice deficient for BMP2 was nonviable and has defects in amnion/chorion and cardiac development. Development 1996;122:2977-86
6. Schneider MD, Gaussin V, Lyons KM. Tempting fate: BMP signals for cardiac morphogenesis. Cytokine Growth Factor Rev 2003;14:1-4.
7. Tomescot A, Leschik J, Bellamy V, Dubois G, Messas E, Bruneval P, Desnos M, Hagège AA, Amit M, Itskovitz J, Menasché P, Pucéat M. Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats. Stem Cells 2007;25:2200-5.
8. Xu M, Wani M, Dai YS, Wang J, Yan M, Ayub A, Ashraf M. Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes. Circulation 2004;110:2658-65
9. Brandon C, Eisenberg LM, Eisenberg CA. Wnt signaling modulates the diversification of hematopoietic cells. Blood 2000;96:4132-41
10. Fox V, Gokhale PJ, Walsh JR, Matin M, Jones M, Andrews PW. Cell-cell signaling through notch regulates human embryonic stem cell proliferation. Stem Cells 2008;123:715-23
11. Zuba-Surma EK, Abdel-Latif A, Case J, Tiwari S, Hunt G, Kucia M, Vincent RJ, Ranjan S, Ratajczak MZ, Srour EF, Bolli R, Dawn B. Sca-1 expression is associated with decreased cardiomyogenic differentiation potential of skeletal muscle-derived adult primitive cells. J Mol Cell Cardiol 2006;41:650-60
12. Wang JS, Shum-Tim D, Galipeau J, Chedrawy E, Eliopoulos N, Chiu RC. Marrow stromal cells for cellular cardiomyoplasty feasibility and potential clinical advantages. J Thorac Cardiovasc Surg 2000;20:999-1006.
13. Wang JS, Shum-Tim D, Chedrawy E, Chiu RC. The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiologic and therapeutic implications. J Thorac Cardiovasc Surg 2001;122:699-705
14. Bianchi G, Muraglia A, Daga A, Corte G, Cancedda R, Quarto R. Microenviornment and stem properties of bone marrow-derived mesenchymal cells. Wound Repair Regen 2001;9:460-6
15. Yau TM, Tomita S, Weisel RD, Jia ZQ, Tumiati LC, Mickle DA, Li RK. Benefical effect of autologous cell transplantation on infarcted heart fuction: comparison between bone marrow stromal cells and heart cells. Ann Thorac Surg 2003;75:169-76
16. Rangappa S, Entwistle JW, Wechsler AS, Kresh JY. Cardiomyocytemediated contact programs human mesenchymal stem cells to express cardiogenic phenotype. J Thorac Cardiovasc Surg 2003;126:124-32.
17. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate in farcted myocardium. Nature 2001;410:701-5
18. Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes Dev 1997;11:3286-305
19. Pandur P, Lasche M, Eisenberg LM, Kuhl M. Wnt11 activation of a non-canonical Wnt signalling pathway was required for cardiogenesis. Nature 2002;418:636-41
20. Koyanagi M, Haendeler J, Badorff C, Brandes RP, Hoffmann J, Pandur P, Zeiher AM, Kuhl M, Dimmeler S. Non-canonical Wnt signaling enhances differentiation of human circulating progenitor cells to cardiomyogenic cells. J Biol Chem 2005;280:16838-42
21. Sabbah HN, Sharov VG, Gupta RC, Mishra S, Rastogi S, Undrovinas AI, Chaudhry PA, Todor A, Mishima T, Tanhehco EJ, Suzuki G. Reversal of chronic molecular and cellular abnormalities due to heart failure by passive mechanical ventricular containment. Circ Res 2003;93:1095-101.
22. Schultheiss TM, Burch JB, Lassar AB. A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev 1997;11:451-62
23. Monzen K, Nagai R, Komuro I. A role for bone morphogenetic protein signaling in cardiomyocyte differentiation. Trends Cardiovasc Med 2002;12:263-9
24. Izumi M, Fujio Y, Kunisada K, Negoro S, Tone E, Funamoto M, Osugi T, Oshima Y, Nakaoka Y, Kishimoto T, Yamauchi-Takihara K, Hirota H. Bone morphogenetic protein-2 inhibits serum deprivation-induced apoptosis of neonatal cardiac myocytes through activation of the Smad1 pathway. J Biol Chem 2001;276:31133-41
25. Kawai T, Takahashi T, Esaki M, Ushikoshi H, Nagano S, Fujiwara H, Kosai K. Efficient cardiomyogenic differentiation of embryonic stem cell by fibroblast growth factor 2 and bone morphogenetic protein 2. Circ J 2002;68:691-702
26. Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, Kinoshita M, Hattori F, Fukami S, Shimazaki T, Ogawa S, Okano H, Fukuda K. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol 2005;23:607-11
27. Shim WS, Jiang S, Wong P, Tan J, Chua YL, Tan YS, Sin YK, Lim CH, Chua T, Teh M, Liu TC, Sim E. Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte like cells. Biochem Biophys Res Commun 2004;324:481-8