Inhibition of cytochrome P4502E1 by chlormethiazole attenuated acute ethanol-induced fatty liver

Chemico-Biological Interactions

Volumn 222, Issue , 2014, Pages 18-26

  Chen, Yang Yang ^a   Zhang, Cui Li ^a   Zhao, Xiu Lan ^a   Xie, Ke Qin ^a   Zeng, Tao ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Alcoholic fatty liver; Autophagy; Binge drinking; Chlormethiazole; CYP2E1; Oxidative stress

Indexed keywords

MUS;

ACYL-COA CARBOXYLASE; ADIPONECTIN; ADIPOQ PROTEIN, MOUSE; CLOMETHIAZOLE; CYTOCHROME P450 2E1 INHIBITOR; DGAT2 PROTEIN, MOUSE; DIACYLGLYCEROL ACYLTRANSFERASE; FATTY ACID SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SREBF1 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL; AUTOPHAGY; BLOOD; DISEASE MODEL; DRUG EFFECTS; FATTY LIVER, ALCOHOLIC; GENETICS; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOLOGY; PHOSPHORYLATION;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; CARBON-CARBON LIGASES; CHLORMETHIAZOLE; CYTOCHROME P-450 CYP2E1 INHIBITORS; DIACYLGLYCEROL O-ACYLTRANSFERASE; DISEASE MODELS, ANIMAL; FATTY ACID SYNTHASES; FATTY LIVER, ALCOHOLIC; MALE; MICE; OXIDATIVE STRESS; PHOSPHORYLATION; PPAR ALPHA; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84908365973     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.08.009     Document Type: Article

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