Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Chen, Jing ^a,b   Ingham, Neil ^a,b   Kelly, John ^c   Jadeja, Shalini ^d,e   Goulding, David ^a   Pass, Johanna ^a,b   Mahajan, Vinit B ^f   Tsang, Stephen H ^g   Nijnik, Anastasia ^a,h   Jackson, Ian J ^d,e   White, Jacqueline K ^a   Forge, Andrew ^c   Jagger, Daniel ^c   Steel, Karen P ^a,b  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF IOWA   (United States)

^g New York Presbyterian Hospital   (United States)

^h MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CONNEXIN 26; CONNEXIN 30; CRE RECOMBINASE; KCNJ10 PROTEIN; KCNQ1 PROTEIN; MEMBRANE PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPINSTER HOMOLOG 2 PROTEIN; TRANSCRIPTION FACTOR SOX10; UNCLASSIFIED DRUG; ANION TRANSPORT PROTEIN; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPNS2 PROTEIN, HUMAN;

ADULT; ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUDITORY RESPONSE; CAPILLARY PERMEABILITY; CELL STRUCTURE; COCHLEA POTENTIAL; CONTROLLED STUDY; CORTI ORGAN; DOWN REGULATION; ENDOTHELIUM CELL; ERYTHROCYTE; GENE; GENE MUTATION; HAIR CELL; HEARING IMPAIRMENT; MALE; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RETINA CAPILLARY; RETINA DEGENERATION; SENSITIVITY ANALYSIS; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINSTER HOMOLOG 2 GENE; STRIA VASCULARIS; THROMBOCYTE; ANALOGS AND DERIVATIVES; ANIMAL; ANTERIOR EYE SEGMENT; COCHLEA; COCHLEAR HAIR CELL; DEFICIENCY; GENETICS; INNER EAR; METABOLISM; ONSET AGE; ORGANOGENESIS; PATHOLOGY; ZEBRA FISH;

AGE OF ONSET; ANIMALS; ANION TRANSPORT PROTEINS; ANTERIOR EYE SEGMENT; COCHLEA; EAR, INNER; HAIR CELLS, AUDITORY; HEARING LOSS; LYSOPHOSPHOLIPIDS; MICE; ORGANOGENESIS; SPHINGOSINE; STRIA VASCULARIS; ZEBRAFISH;

EID: 84908340276     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004688     Document Type: Article

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